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Diagnostic significance of serum levels of serum amyloid A,procalcitonin,and high-mobility group box 1 in identifying necrotising enterocolitis in newborns

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2003-2011页

作者： Li-Ming Guo zhi-Hui jiang Hong-Zhen Liu Lei Zhang Department of General Surgery Qingdao Women and Children’s HospitalQingdao 266000Shandong ProvinceChina Department of Pediatric Surgery Children's Hospital Affiliated to Shandong UniversityJinan 250022Shandong ProvinceChina Department of Pediatric Surgery Jinan Children's HospitalJinan 250022Shandong ProvinceChina Department of Pediatric Surgery Qilu Hospital of Shandong University(Qingdao)Qingdao 260010Shandong ProvinceChina

BACKGROUND Necrotising enterocolitis(NEC)is a critical gastrointestinal emergency affecting premature and low-birth-weight *** amyloid A(SAA),procalcitonin(PCT),and high-mobility group box 1(HMGB1)have emerged as potential biomarkers for NEC due to their roles in inflammatory response,tissue damage,and immune *** To evaluate the diagnostic value of SAA,PCT,and HMGB1 in the context of NEC in *** The study retrospectively analysed the clinical data of 48 newborns diagnosed with NEC and 50 healthy newborns admitted to the ***,radiological,and laboratory findings,including serum SAA,PCT,and HMGB1 Levels,were collected,and specific detection methods were *** diagnostic value of the biomarkers was evaluated through statistical analysis,which was performed using chi-square test,t-test,correlation analysis,and receiver operating characteristic(ROC)*** The study demonstrated significantly elevated levels of serum SAA,PCT,and HMGB1 Levels in newborns diagnosed with NEC compared with healthy *** correlation analysis indicated strong positive correlations among serum SAA,PCT,and HMGB1 Levels and the presence of *** analysis revealed promising sensitivity and specificity for serum SAA,PCT,and HMGB1 Levels as potential diagnostic *** combined model of the three biomarkers demonstrating an extremely high area under the curve(0.908).CONCLUSION The diagnostic value of serum SAA,PCT,and HMGB1 Levels in NEC was *** biomarkers potentially improve the early detection,risk stratification,and clinical management of critical *** findings suggest that these biomarkers may aid in timely intervention and the enhancement of outcomes for neonates affected by NEC.

关键词： Serum amyloid A Procalcitonin High-mobility group box 1 Necrotising enterocolitis in newborns Serum biomarkers

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Interpenetrating network-reinforced gel polymer electrolyte for ultra-stable lithium−iodine batteries

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Carbon Energy 2024年第6期6卷 234-247页

作者： Ying jiang Peng Huang Minman Tong Bingxin Qi Tao Sun Zhongyun Xian wen Yan Chao Lai School of Chemistry and Materials Science Jiangsu Normal UniversityXuzhouJiangsuChina

Li-I_(2) batteries have attracted much interest due to their high capacity,exceptional rate performance,and low *** so,the problems of unstable Li anode/electrolyte interface and severe polyiodide shuttle in Li-I_(2) batteries need to be ***,the interfacial reactions on the Li anode and I_(2) cathode have been effectively optimized by employing a well-designed gel polymer electrolyte strengthened by cross-linked Ti-O/Si-O(GPETS).The interpenetrating network-reinforced GPETS with high ionic conductivity(1.88×10^(-3)S cm^(-1)at 25℃)and high mechanical strength endows uniform Li deposition/stripping over 1800 h(at 1.0mA cm^(-2),with a plating capacity of 3.0mAh cm^(-2)).Moreover,the GPETS abundant in surface hydroxyls is capable of capturing soluble polyiodides at the interface and accelerating their conversion kinetics,thus synergistically mitigating the shuttle *** from these properties,the use of GPETS results in a high capacity of 207 mAh g^(-1)(1 C)and an ultra-low fading rate of 0.013%per cycle over 2000 cycles(5 C).The current study provides new insights into advanced electrolytes for Li-I_(2) batteries.

关键词： electrode/electrolyte interface gel polymer electrolytes lithium dendrites lithium−iodine batteries polyiodide shuttle

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Deliberate self-harm among pediatric psychiatric inpatients in China:A single-center retrospective study

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World Journal of Psychiatry 2024年第3期14卷 398-408页

作者： Xing-zhi jiang Huan-Huan Li Zhen-Zhen Yu Chen Wang Department of Child and Adolescent Psychiatry Shenzhen Kangning HospitalShenzhen Mental Health CenterShenzhen Key Laboratory for Psychological Healthcare and Shenzhen Institute of Mental HealthShenzhen 518020Guangdong ProvinceChina Department of Psychiatry Xiamen Xianyue HospitalXiamen 361012Fujian ProvinceChina Department of Geriatric Medicine Dalian Medical UniversityDalian 116000Liaoning ProvinceChina Department of Neurology The Second Affiliated Hospital of Xiamen Medical CollegeXiamen 361000Fujian ProvinceChina Department of Neurology and Department of Neuroscience The First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamen 361000Fujian ProvinceChina

BACKGROUND For children and adolescents,deliberate self-harm(DSH)is becoming a mental health problem of *** several studies on the prevalence and factors of DSH in the world,there is little information on DSH among children and adolescents in *** study explores the prevalence,types,associated risk factors and tendency of DSH in pediatric psychiatric inpatients in *** To understand the situation of DSH among hospitalized children and adolescents and its related *** In this study,we retrospectively studied 1414 hospitalized children and adolescents with mental illness at Xiamen Mental Health Center from 2014 to 2019,extracted the demographic and clinical data of all patients,and analyzed clinical risk factors of *** A total of 239(16.90%)patients engaged in at least one type of DSH in our ***(n=115,48.12%)was the most common type of ***(n=171,71.55%)were more likely to engage in DSH than males(n=68,28.45%).DSH was positively associated with depressive disorders[OR=3.845(2.196-6.732);P<0.01],female[OR=2.536(1.815-3.542);P<0.01],parental marital status[OR=5.387(2.254-12.875);P<0.01]and negative family history of psychiatric illness[OR=7.767(2.952-20.433);P<0.01],but not with occupation,substance use and history of physical *** Our findings suggest that for patients with depression,females,an abnormal marriage of parents,and no history of mental illness,attention should be paid to the occurrence of DSH.

关键词： Deliberate self-harm Children Adolescent Psychiatric inpatients Retrospective study

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Antibacterial properties of cerium oxide nanoparticles:Recent progresses and future challenges

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Particuology 2024年第10期93卷 264-283页

作者： Heishu Zheng Jiajing Tang Yanhua Wei Xi Deng Yingjuan Zhang Xiangyu Ma Xudong jiang zhi Ping Xu Hongbing Liao College&Hospital of Stomatology Guangxi Medical UniversityNanning530021China Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction Guangxi Medical UniversityNanning530021China The First Affiliated Hospital of Guangxi Medical University Nanning530021China School of Medicine Guangxi University of Science and TechnologyLiuzhou545005China Institute of Biomedical Health Technology and Engineering and Institute of Systems and Physical Biology Shenzhen Bay LaboratoryShenzhen518107China Australian Institute for Bioengineering and Nanotechnology(Bld 75) The University of QueenslandSt LuciaQueensland 4074Australia

Use of cerium oxide nanoparticles(CeO_(2) NPs)to optimize management of resistant microorganisms has received increasing attention due to non-specific activity of inorganic antibacterial *** the mechanism of action is essential to elucidating the antibacterial activity of CeO_(2) NPs against ***,this review aims to summarize the antibacterial mechanisms of CeO_(2) NPs and correlate the structural and physicochemical properties of CeO_(2) NPs to their antibacterial *** further summarize the strategies for the improvement of the antibacterial performance of CeO_(2) NPs and provide our opinions for future challenges as a conclusion.

关键词： Nanoparticles Cerium oxide Antibacterial activity Nanozyme Fenton reaction

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High Speed Sintering:Assessing the Influence of Energy Input on Microstructure and Mechanical Properties of Polyether Block Amide(PEBA)Parts

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Chinese Journal of Polymer Science 2024年第5期42卷 675-682,I0004,I0010页

作者： jiang-Tao Sun zhi-Yong Fan Yi-Wei Mao Wei Li Wei Zhu Dao-Sheng Cai Qing-Song Wei State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan430074China State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan430074China National Engineering Research Centre for High Efficiency Grinding Hunan UniversityChangsha410082China Wuhan EasyMFG Technology CO. LTDWuhan430074China

High speed sintering,a new powder-bed fusion additive manufacturing technology,utilizes infrared lights(IR)to intensely heat and melt polymer *** presence of defects such as porosity,which is associated with particle coalescence,is highly dependdent on the level of energy *** study investigate the influcence of energy input on porosity and its subsequent effects on the mechanical properties and microstructures of PEBA *** parts were manufactured with a variety of lamp powers,resulting in a range of energy input levels spanning from low to ***,they underwent testing using Archimedes’method,followed by tensile *** porosity,mechanical characteristics,and energy input exhibit a strong correlation;inadequate energy input was the primary cause of pore *** the reduced IR light power resulted in the following outcomes:porosity,ultimate tensile strength,and elongation of 1.37%,7.6 MPa,and 194.2%,*** the energy input was further increased,the porosity was reduced to as low as 0.05%and the ultimate tensile strength and elongation were increased to their peak values of 233.8%and 9.1 MPa,respectively.

关键词： High speed sintering Additive manufacturing Energy input Powder bed fusion PEBA

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A Model for Detecting Fake News by Integrating Domain-Specific Emotional and Semantic Features

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Computers, Materials & Continua 2024年第8期80卷 2161-2179页

作者： wen jiang Mingshu Zhang Xu’an Wang Wei Bin Xiong Zhang Kelan Ren Facheng Yan College of Cryptography Engineering Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of Network and Information Security Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of CTC&Information Engineering Engineering University of People’s Armed PoliceMinistry of EducationXi’an710086China

With the rapid spread of Internet information and the spread of fake news,the detection of fake news becomes more and more *** detection methods often rely on a single emotional or semantic feature to identify fake news,but these methods have limitations when dealing with news in specific *** order to solve the problem of weak feature correlation between data from different domains,a model for detecting fake news by integrating domain-specific emotional and semantic features is *** method makes full use of the attention mechanism,grasps the correlation between different features,and effectively improves the effect of feature *** algorithm first extracts the semantic features of news text through the Bi-LSTM(Bidirectional Long Short-Term Memory)layer to capture the contextual relevance of news ***-BiLSTM is then used to extract emotional features and predict the probability of positive and negative emotions in the *** then uses domain features as an enhancement feature and attention mechanism to fully capture more fine-grained emotional features associated with that ***,the fusion features are taken as the input of the fake news detection classifier,combined with the multi-task representation of information,and the MLP and Softmax functions are used for *** experimental results show that on the Chinese dataset Weibo21,the F1 value of this model is 0.958,4.9% higher than that of the sub-optimal model;on the English dataset FakeNewsNet,the F1 value of the detection result of this model is 0.845,1.8% higher than that of the sub-optimal model,which is advanced and feasible.

关键词： Fake news detection domain-related emotional features semantic features feature fusion

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Cross-Target Stance Detection with Sentiments-Aware Hierarchical Attention Network

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Computers, Materials and Continua 2024年第1期81卷 789-807页

作者： Ren, Kelan Yan, Facheng Chen, Honghua jiang, wen Wei, Bin Zhang, Mingshu College of Cryptographic Engineering Engineering University of PAP Xi'an 710086 China

The task of cross-target stance detection faces significant challenges due to the lack of additional background information in emerging knowledge domains and the colloquial nature of language patterns. Traditional stance detection methods often struggle with understanding limited context and have insufficient generalization across diverse sentiments and semantic structures. This paper focuses on effectively mining and utilizing sentimentsemantics knowledge for stance knowledge transfer and proposes a sentiment-aware hierarchical attention network (SentiHAN) for cross-target stance detection. SentiHAN introduces an improved hierarchical attention network designed to maximize the use of high-level representations of targets and texts at various fine-grain levels. This model integrates phrase-level combinatorial sentiment knowledge to effectively bridge the knowledge gap between known and unknown targets. By doing so, it enables a comprehensive understanding of stance representations for unknown targets across different sentiments and semantic structures. The model's ability to leverage sentimentsemantics knowledge enhances its performance in detecting stances that may not be directly observable from the immediate context. Extensive experimental results indicate that SentiHAN significantly outperforms existing benchmark methods in terms of both accuracy and robustness. Moreover, the paper employs ablation studies and visualization techniques to explore the intricate relationship between sentiment and stance. These analyses further confirm the effectiveness of sentence-level combinatorial sentiment knowledge in improving stance detection capabilities. © 2024 Tech Science Press. All rights reserved.

关键词： Semantics

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Chronic infectious unilateral giant thyroid cyst related to diabetes mellitus:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1497-1503页

作者： jiang-Bo Liu Shi-Lei Zhang wen-Long jiang Hai-Kuan Sun Hao-Chen Yang Department of Thyroid and Breast Surgery The First Affiliated HospitalCollege of Clinical MedicineHenan University of Science and TechnologyLuoyang 471000Henan ProvinceChina Clinical Medicine School The First Clinical CollegeChongqing Medical UniversityChongqing 400016China

BACKGROUND Patients rarely develop complicated infections in thyroid ***,we describe a patient with chronic infected unilateral giant thyroid cyst related to diabetes mellitus(DM).CASE SUMMARY A 66-year-old male was admitted due to an evident neck lump for 5 d after approximately 40 years of gradually progressive neck mass and 7 years of *** ultrasound and computed tomography scan showed a giant lump in the left thyroid gland *** was diagnosed with a large thyroid nodule complicated by tracheal dislocation and had surgical *** exploration revealed evident inflammatory edema and exudation between the left anterior neck muscles,the nodule and glandular ***,inflammatory lesions did not affect major neck ***,a left partial thyroidectomy was *** observation showed that the cystic thyroid mass consisted of extensive cystic wall calcification and was rich in massive rough sand-like calculi content and purulent *** pathology confirmed benign thyroid cyst with chronic *** The progression of this chronic infectious unilateral giant thyroid cyst may have been related to DM,and identifying blood vessels involvement can prevent serious complications during operation.

关键词： Thyroid nodule Infection Diabetes mellitus Surgery Case report

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PACS gene family-related neurological diseases: limited genotypes and diverse phenotypes

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World Journal of Pediatrics 2024年第1期20卷 82-91页

作者： Han Zhang Kai Gao Shuang Wang Yue-Hua Zhang zhi-Xian Yang Ye Wu Yu-Wu jiang Department of Pediatrics Peking University First Hospital.No.1 Xi'an Men StreetWest DistrictBeijing 100034China Bejing Key Laboratory of Molecular Diagnosis and Study on Pediatric Genetic Diseases BeijingChina Children Epilepsy Center Peking University First HospitalBeijingChina Key Laboratory for Neuroscience Ministry of Education/National Health and Family Planning CommissionPeking UniversityBeijingChina Center of Epilepsy Beijing Institute for Brain DisordersBeijingChina

Background The PACS gene family has been demonstrated to be related to intracellular vesicular *** phenotypic manifestations caused by the pathogenic variants of PACS include epilepsy,intellectual disability/developmental delay,and malformations,such as facial *** We identified seven new cases with pathogenic or likely pathogenic PACS variants using next-generation *** information obtained from these patients was analyzed along with that obtained from previously reported *** With the inclusion of the newly diagnosed cases in this study,103 cases with PACS gene family-related neurological diseases were reported,of which 43 were PACS2-related cases and the remaining were PACSI-related *** patients had seizures,which have been reported to be effectively controlled by several types of anti-seizure medications(ASMs).The most efficacious and frequently prescribed ASMs included sodium valproate(43.3%,13/30),oxcarbazepine/carbamazepine(26.7%,8/30),and levetiracetam(20%,6/30).Almost all patients had intellectual disability/developmental *** most common pathogenic missense variants were PACSI ***203Trp and PACS2 *** addition,we report a patient carrying a likely pathogenic copy number variation(CNV)(de novo heterozygous deletion of chr14:105821380-106107443,286 kilobase,destroyed part of the furin-binding region domain and the protein structure after it)with more severe and refractory late-onset *** The clinical phenotypes of the different PACS heterozygous missense variants were *** pathogenic variant sites of PACSI and PACS2 were quite limited but located in different regions.A CNV destroying part of the PACS2 gene might also be *** findings may provide an important clue for further functional studies on the pathogenic mechanism of neurological disorders related to the PACS gene family.

关键词： Developmental delay Epilepsy Intellectual disability PACSI PACS2

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Structural Properties of Ions and Polyelectrolytes in Aqueous Solutions under External Electric Fields:The Sign Effect

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Chinese Journal of Polymer Science 2024年第9期42卷 1341-1352,I0007页

作者： Cheng-jiang Lin Jun-Jun Wang Yuan jiang Shu-Li Chen Hong-Fei Li wen-Han Zhao Qing-Rong Huang Chang-Ru Rong Xiao-Zheng Duan State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei230026China National Key Laboratory of Advanced Vehicle Integration and Control China FAW Group Co.Ltd.Changchun130013China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200438China Department of Food Science Rutgers University65 Dudley RoadNew BrunswickNew Jersey08901USA

We utilize molecular dynamics simulations to investigate the microstructures of ions and polyelectrolytes in aqueous solutions under external electric *** focusing on the multi-body interactions between ionic components and H_(2)O molecules,as well as their responses to the external electric fields,we clarify several nontrivial molecular features of the ionic and polyelectrolyte solutions,such as the solvations of cations and anions,clustering of the ions,and dispersions/aggregations of polyelectrolyte chains,as well as the corresponding responses of H_(2)O molecules in these *** simulations illustrate the variations in structures of ionic solutions caused by reversing the charge sign of the ions,and elucidate the disparity in structures between anionic and cationic polyelectrolyte solutions in the presence of the external electric *** work clarifies the mechanism for the alternations in complex multi-body interactions in aqueous solutions caused by the application electric field,which can contribute to the fundamental understanding of the physical and chemical natures of ion-containing and charged polymeric systems.

关键词： Polyelectrolyte Ions Aqueous solutions External electric fields Asymmetric dipole

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