检索结果-南通市图书馆

Cholangiojejunostomy for multiple biliary ducts in living donor liver transplantation: A case report

World Journal of Clinical Cases 2021年第11期9卷 2649-2654页

作者： Fei Xiao Li-Ying Sun Lin Wei zhi-Gui Zeng Wei Qu Ying Liu Hai-Ming Zhang zhi-jun zhu Liver Transplantation Center National Clinical Research Center for Digestive DiseasesBeijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Organ Transplantation Liao Cheng People's HospitalLiaocheng 252000Shandong ProvinceChina Clinical Center for Pediatric Liver Transplantation Capital Medical UniversityBeijing 100050China Beijing Key Laboratory of Tolerance Induction and Organ Protection in Transplantation Capital Medical UniversityBeijing 100050China Department of Intensive Care Unit Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Liver Transplantation Center National Clinical Research Center for Digestive DiseasesCapital Medical UniversityBeijing 100050China

BACKGROUND Laparoscopic living donor hepatectomy(LLDH)has been successfully carried out in several transplant *** reconstruction is key in living donor liver transplantation(LDLT).Reliable biliary reconstruction can effectively prevent postoperative biliary stricture and *** preoperative magnetic resonance cholangiopancreatography and intraoperative indocyanine green cholangiography have been shown to be helpful in determining optimal division points,biliary variability and limitations associated with LLDH,multiple biliary tracts are often encountered during surgery,which inhibits biliary reconstruction.A reliable cholangiojejunostomy for multiple biliary ducts has been utilized in *** procedure provides a reference for multiple biliary reconstructions after *** SUMMARY A 2-year-old girl diagnosed with ornithine transcarbamylase deficiency required liver *** to the scarcity of deceased donors,she was put on the waiting list for *** father was a suitable donor;however,after a rigorous evaluation,preoperative magnetic resonance cholangiopancreatography examination of the donor indicated the possibility of multivessel variation in the biliary ***,a laparoscopic left lateral section was performed on the donor,which met the estimated graft-to-recipient weight *** intraoperative indocyanine green cholangiography,4 biliary tracts were confirmed in the *** was difficult to reform the intrahepatic bile ducts due to their openings of more than 5 mm.A reliable cholangiojejunostomy was,therefore,utilized:Suture of the jejunum to the adjacent liver was performed around the bile duct openings with 6/0 absorbable *** the last follow-up(1 year after surgery),the patient was *** Intrahepatic cholangiojejunostomy is reliable for multiple biliary ducts after LLDH in LDLT.

关键词： Cholangiojejunostomy Living donor liver transplantation Laparoscopic left lateral section Multiple biliary ducts Treatment Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Coexistent Kaposi sarcoma and post-transplant lymphoproliferative disorder in the same lymph nodes after pediatric liver transplantation:A case report

引用

World Journal of Clinical Cases 2022年第25期10卷 9004-9011页

作者： Shu-Hong Zhang Guang-Yong Chen zhi-jun zhu Lin Wei Ying Liu Jing-Yi Liu Department of Pathology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Liver Transplantation Center National Clinical Research Center for Digestive DiseasesBeijing Friendship HospitalCapital Medical UniversityBeijing 100050China Clinical Center for Pediatric Liver Transplantation Capital Medical UniversityBeijing 100050China Department of Critical Liver Diseases Liver Research CenterBeijing Friendship HospitalCapital Medical UniversityBeijing 100050China

BACKGROUND Kaposi sarcoma and post-transplant lymphoproliferative disorder have been occasionally reported in post-liver transplant ***,the simultaneous occurrence of these two diseases in the same lymph nodes is very *** SUMMARY We report the case of a 19-mo-old boy,who presented with intermittent fever and enlarged cervical lymph nodes after liver *** cervical lymph nodes were biopsied,and the histopathological examinations revealed multifocal hyperplasia of spindle cells around small blood vessels,extravasated erythrocytes,and heavy infiltration of plasma cells in the cortex and medulla of the lymph *** immunohistochemical analyses of spindle cells revealed positive expression of CD34,CD31,erythroblast transformation-specific-related gene,friend leukemia integration 1,and human *** lymphoproliferative lesions expressed CD38,CD138,and multiple myeloma ***-Barr encoded RNA in situ hybridization demonstrated Epstein-Barr virus-positive lymphoid ***,we diagnosed the coexistence of Kaposi sarcoma and post-transplant lymphoproliferative disorder(plasmacytic hyperplasia)in the same lymph *** strategy included anti-CD20 monoclonal antibody(rituximab)and discontinuation of the immunosuppressant *** node biopsies during follow-up examinations revealed lymphoid *** The rare coexistence of Kaposi sarcoma and post-transplant lymphoproliferative disorder in the same lymph nodes post-liver transplantation possibly associates with immunodeficiency and Epstein-Barr virus and human herpesvirus-8 coinfection.

关键词： Kaposi sarcoma Post-transplant lymphoproliferative disorder Liver transplantation Epstein-Barr virus infections Human herpesvirus-8 Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Balloon dilatation for treatment of hepatic venous outflow obstruction following pediatric liver transplantation

引用

World Journal of Gastroenterology 2017年第46期23卷 8227-8234页

作者： zhi-Yuan Zhang Long Jin Guang Chen Tian-Hao Su zhi-jun zhu Li-Ying Sun Zhen-Chang Wang Guo-Wen Xiao Department of Interventional Radiology Beijing Friendship HospitalCapital Medical University Department of Transplantation Surgery Beijing Friendship HospitalCapital Medical University Department of Radiology Beijing Friendship HospitalCapital Medical University

AIM To assess the efficacy and safety of balloon dilatation for the treatment of hepatic venous outflow obstruction(HVOO) following pediatric liver *** A total of 246 pediatric patients underwent liver transplantation at our hospital between june 2013 and September 2016. Among these patients, five were ultimately diagnosed with HVOO. Seven procedures(two patients underwent two balloon dilatation procedures) were included in this analysis. The demographic data,types of donor and liver transplant, interventional examination and therapeutic outcomes of these five children were analyzed. The median interval time between pediatric liver transplantation and balloon dilatation procedures was 9.8 mo(range: 1-32).RESULTS Five children with HVOO were successfully treated by balloon angioplasty without stent placement, with seven procedures performed for six stenotic lesions. All children underwent successful percutaneous intervention. Among these five patients, four were treated by single balloon angioplasty, and these patients did not develop recurrent stenosis. In seven episodes of balloon angioplasty across the stenosis, the pressure gradient was 12.0 ± 8.8 mm Hg before balloon dilatation and 1.1 ± 1.5 mm Hg after the procedures, which revealed a statistically significant reduction(P < 0.05). The overall technical success rate among these seven procedures was 100%(7/7), and clinical success was achieved in all five patients(100%). The patients were followed for 4-33 mo(median: 15 mo). No significant procedural complications or procedurerelated deaths *** Balloon dilatation is an effective and safe therapeutic option for HVOO in children undergoing pediatric liver transplantation. Venous angioplasty is also recommended in cases with recurrent HVOO.

关键词： Hepatic venous outflow obstruction Pediatric liver transplantation Percutaneous transluminal balloon dilatation Pressure gradient Recurrent

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of cytomegalovirus infection on biliary disease after liver transplantation-maybe an essential factor

引用

World Journal of Clinical Cases 2021年第35期9卷 10792-10804页

作者： Jing-Yi Liu Jian-Rui Zhang Li-Ying Sun zhi-jun zhu Lin Wei Wei Qu zhi-Gui Zeng Ying Liu Xin-Yan Zhao Liver Transplantation Center Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Clinical Center for Pediatric Liver Transplantation Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China National Clinical Research Center for Digestive Diseases Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Intensive Care Unit Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China

BACKGROUND Cytomegalovirus(CMV)infection is common in liver transplant(LT)_recipients,and biliary complications occur in a large number of *** has been reported that CMV-DNA is more detectable in bile than in *** To investigate the effects of CMV infection on biliary complications by comparing the levels of CMV-DNA in the bile and blood of patients after *** We conducted a retrospective analysis of 57 patients who underwent LT,10 of these patients had no biliary complications and 47 patients had biliary *** also compared the levels of CMV-DNA in patients’bile and blood,which were sampled *** used RNAscope technology to identify CMV in paraffin-embedded liver *** CMV-DNA was not detected in bile samples and was detected in 2 blood samples from patients without biliary *** the 47 patients with biliary complications,CMV-DNA was detected in 22 bile samples and 8 blood samples,both bile and blood samples were positive for CMV-DNA in 6 *** identification rate of CMV-DNA in blood was 17.0%,and was 46.8%in ***,tissue samples from 4 patients with biliary complications tested positive using RNAscope technology but were negative with hematoxylin and eosin *** the follow-up period,graft failure occurred in 13 patients with biliary complications,8 of whom underwent retransplantation,and 3 ***-DNA in bile was detected in 9 of 13 patients with graft *** In patients with biliary complications,the identification rate of CMV-DNA in bile was higher than that in *** CMV-DNA negative patients with biliary complications should still be monitored for CMV-related biliary tract *** occult CMV infection may also be a contributing etiological factor in the development of graft failure.

关键词： Liver transplantation Cytomegalovirus infection Graft failure Biliary complications RNAscope in situ hybridization Retrospective study

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of pure laparoscopic surgery on bile duct division of living donor left lateral section procurement

引用

Hepatobiliary Surgery and Nutrition 2023年第3期12卷 328-340,I0008-I0011页

作者： Hai-Ming Zhang Lin Wei Hong-Yu Li Li-Ying Sun Wei Qu zhi-Gui Zeng Ying Liu zhi-jun zhu Beijing Friendship Hospital Capital Medical UniversityBeijingChina Clinical Center for Pediatric Liver Transplantation Capital Medical UniversityBeijingChina National Clinical Research Center for Digestive Diseases BeijingChina

Background:Although laparoscopic living donor left lateral section liver procurements represents an established and safe procedure,there remains much discussion on this *** particular,the issue of whether laparoscopic living donor liver procurement increases the difficulty of the surgery and potential complications for recipients continue to confound experts in this ***:In this report,data from 180 cases of living donor left lateral section liver transplantation patients were analyzed *** these 180 cases,106 grafts were procured by open surgery and 74 by pure laparoscopic ***:While surgery durations and blood loss were decreased in donors from the laparoscopic surgery group,increased biliary openings of grafts and relatively high peak aspartate aminotransferase(AST)levels were present in both donors and recipients with this ***:Laparoscopic living donor left lateral section liver procurement represents a safe and effective procedure for both donors and ***,laparoscopic surgery can more frequently lead to multiple biliary tracts in the graft and its impact on the prognosis of recipients remains *** of routine X-ray based intraoperative cholangiography may help to reduce this problem.

关键词： Pure laparoscopic surgery living donor liver transplantation(LDLT) biliary complication prognosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of liver transplantation with primary hyperoxaluria type 1:Five case reports and review of literature

引用

World Journal of Clinical Cases 2023年第5期11卷 1068-1076页

作者： Xin-Yue Wang zhi-Gui Zeng zhi-jun zhu Lin Wei Wei Qu Ying Liu Yu-Le Tan jun Wang Hai-Ming Zhang Wen Shi Li-Ying Sun Department of Critical Liver Diseases Liver Research CenterBeijing Friendship HospitalCapital Medical UniversityBeijing 101100China Liver Transplantation Center Beijing Friendship HospitalCapital Medical UniversityBeijing 101100China Clinical Center for Pediatric Liver Transplantation Capital Medical UniversityBeijing 101100China National Clinical Research Center for Digestive Diseases Beijing Friendship HospitalCapital Medical UniversityBeijing 101100China Beijing Clinical Research Institute Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China

BACKGROUND Primary hyperoxaluria type 1(PH1)is a rare autosomal recessive disease stemming from a deficiency in liver-specific alanine-glyoxylate aminotransferase,resulting in increased endogenous oxalate deposition and end-stage renal *** transplantation is the only effective ***,its approach and timing remain *** SUMMARY We retrospectively analyzed 5 patients diagnosed with PH1 from the Liver Transplant Center of the Beijing Friendship Hospital from March 2017 to December *** cohort included 4 males and 1 *** median age at onset was 4.0 years(range:1.0-5.0),age at diagnosis was 12.2 years(range:6.7-23.5),age at liver transplantation(LT)was 12.2 years(range:7.0-25.1),and the follow-up time was 26.3 mo(range:12.8-40.1).All patients had delayed diagnosis,and 3patients had progressed to end-stage renal disease by the time they were *** patients received preemptive LT;their estimated glomerular filtration rate was maintained at>120 mL/min/1.73 m2,indicating a better *** patients received sequential liver and kidney *** transplantation,serum and urinary oxalate decreased,and liver function *** the last follow-up,the estimated glomerular filtration rates of the latter 3 patients were 179,52 and 21 mL/min/1.73 *** Different transplantation strategies should be adopted for patients based on their renal function ***-LT offers a good therapeutic approach for PH1.

关键词： Primary hyperoxaluria type 1 Liver transplantation Combined liver and kidney transplantation Sequential liver and kidney transplantation Renal calculi End-stage renal disease Case reports

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

FPGA-based position reconstruction method for neutron beam flux spatial distribution measurement in BNCT

引用

Nuclear Science and Techniques 2024年第3期35卷 96-108页

作者： Wei Jiang Ping Cao Yi-Ming Wu Xian-Ke Liu zhu-jun Fang zhi-Yong Zhang Bin Shi jun Chen State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China National Key Laboratory for Metrology and Calibration Techniques China Institute of Atomic EnergyBeijing 102413China

A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy(BNCT)is being developed based on the two-dimensional Micromegas *** address the issue of long processing times in traditional offline position reconstruction methods,this paper proposes a field programmable gate array based online position reconstruction method utilizing the micro-time projection chamber *** method encapsulates key technical aspects:a self-adaptive serial link technique built upon the dynamical adjustment of the delay chain length,fast sorting,a coordinate-matching technique based on the mapping between signal timestamps and random access memory(RAM)addresses,and a precise start point-merging technique utilizing a circular combined *** performance test of the selfadaptive serial link shows that the bit error rate of the link is better than 10-12 at a confidence level of 99%,ensuring reliable data *** experiment utilizing the readout electronics and Micromegas detector shows a spatial resolution of approximately 1.4 mm,surpassing the current method’s resolution level of 5 *** beam experiment confirms that the readout electronics system can obtain the flux spatial distribution of neutron beams online,thus validating the feasibility of the position reconstruction *** online position reconstruction method avoids traditional methods,such as bubble sorting and traversal searching,simplifies the design of the logic firmware,and reduces the time complexity from O(n2)to O(n).This study contributes to the advancement in measuring neutron beam flux for BNCT.

关键词： Position reconstruction FPGA Readout electronics Neutron flux spatial distribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evolution of Proinflammatory Cytokines in Hepatocellular Carcinoma Patients Undergoing Orthotopic Liver Transplantation

引用

Clinical oncology and cancer researeh 2011年第1期8卷 38-41页

作者： Yu-liang WANG Yu ZHANG zhi-jun zhu Rui-fa HAN Tianjin Institute of Urology Tianjin Medical University Tianjin 300211 China Department of Anesthesia Tianjin Medical University Cancer Institute and Hospital Tianjin 300060 China Orient Organ Transplant Center First Central Clinic Institute of Tianjin Medical University Key Lab for Critical Care Medicine of the Ministry of Health Tianjin 300192 China.

OBJECTIVE To analyze the expression and levels of serum proinflammatory cytokines including tumor necrosis factor alpha （TNF-α）, and interleukin （IL）-6 in patients with hepatocellular carcinoma （HCC）, who received orthotopic liver transplantation （OLT）.METHODS The blood samples of 20 consecutive HCC patients who underwent liver transplantation were detected and analyzed for the clinical serum biochemical parameters, TNF-α and *** samples were drawn from the radial artery at planned time points： preoperatively, intraoperatively, and *** of serum TNF-α and IL-6 were detected with enzymelinked immunosorbent assay （ELISA）.RESULTS The levels of serum TNF-αand IL-6 increased significantly at reperfusion phase compared with those detected preoperatively （P 〈 0.01）, and the level of serum IL-6 remained significantly higher until the third day after the liver transplantation. There was a significant correlation between TNF-αand IL-6 （P〈0.001）.CONCLUSION This research into the effects of the proinflammatory cytokines on liver transplantation has provided new insights into the mechanisms of ischemia and reperfusion injury to OLT.

关键词： liver transplantation carcinoma hepatocellular reperfusion cytokines

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cytotoxic terpenes from Abies sibirica

引用

Chinese Chemical Letters 2012年第11期23卷 1251-1253页

作者： Gui Rong Wang Yong Li Li Wei Dong Zhang Xian Wen Yang Wen Cong Liu Ji Ye zhi jun zhu Hong Chen Department of Phytochemistry School of PharmacySecond Military Medical UniversityShanghai 200433China Department of Pharmacognosy Jilin Agricultural UniversityChangchun 130118China School of Pharmacy Shanghai Jiao Tong UniversityShanghai 200240China

One new and 16 known compounds were isolated from Abies sibirica. Their structures were assigned mainly on the basis of NMR and MS spectroscopic data. In bioassay for anti-proliferative activity against four human tumor cells, compound 7 exhibited selective anti-proliferative activity against COLO-205 tumor cell with an IC50 value of 0.9 μg/mL.

关键词： Abies sibirica Pinaceae Terpenes Triterpene

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

First case of cross-auxiliary double domino donor liver transplantation

引用

World Journal of Gastroenterology 2017年第44期23卷 7939-7944页

作者： zhi-jun zhu Lin Wei Wei Qu Li-Ying Sun Ying Liu zhi-Gui Zeng Liang Zhang En-Hui He Hai-Ming Zhang Ji-Dong Jia Zhong-Tao Zhang Liver Transplantation Center Beijing Friendship Hospital Capital Medical University National Clinical Research Center for Digestive Diseases Beijing Friendship Hospital Capital Medical University Beijing Key Laboratory of Tolerance Induction and Organ Protection in Transplantation Beijing Friendship Hospital Capital Medical University

We report a case of double domino liver transplantation in a 32-year-old woman who was diagnosed with familial amyloid polyneuropathy(FAP) and liver dysfunction. A two-stage surgical plan was designed, and one domino graft was implanted during each stage. During the firststage, an auxiliary domino liver transplantation was conducted using a domino graft from a 4-year-old female child with Wilson's disease. After removing the right lobe of the FAP patient's liver, the graft was rotated 90 degrees counterclockwise and placed along the right side of the inferior vena cava(IVC). The orifices of the left, middle, and right hepatic veins were reconstructed using an iliac vein patch and then anastomosed to the right side of the IVC. Thirty days later, a second domino liver graft was implanted. The second domino graft was from a 3-yearold female child with an ornithine carbamyl enzyme defect, and it replaced the residual native liver(left lobe). To balance the function and blood flow between the two grafts, a percutaneous transcatheter selective portal vein embolization was performed, and "the left portal vein" of the first graft was blocked 9 mo after the second transplantation. The liver function indices, blood ammonia, and 24-h urinary copper levels were normal at the end of a 3-year follow-up. These two domino donor grafts from donors with different metabolic disorders restored normal liver function. Our experience demonstrated a new approach for resolving metabolic disorders with domino grafts and utilizing explanted livers from children.

关键词： Domino liver transplantation Familial amyloid polyneuropathy Double graft Wilson's disease Ornithine transcarbamylase deficiency Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：