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直接植块法构建人胚雪旺细胞人工神经

复旦学报（医学版） 2004年第5期31卷 512-514,F003页

作者：吴志伟陈峥嵘汪洋程飚复旦大学附属中山医院骨科上海医学院解剖与组织胚胎学系上海200032

目的　探索人组织工程神经的构造方法。方法　应用直接植块法将人胚雪旺细胞种植于鼠尾胶包埋的聚羟基乙酸和聚乳酸共聚物支架上 ,观察细胞在支架上的吸附迁移和生长情况。结果　直接植块法能在较短时间内使人胚雪旺细胞长满支架表面 ,... 详细信息

目的　探索人组织工程神经的构造方法。方法　应用直接植块法将人胚雪旺细胞种植于鼠尾胶包埋的聚羟基乙酸和聚乳酸共聚物支架上 ,观察细胞在支架上的吸附迁移和生长情况。结果　直接植块法能在较短时间内使人胚雪旺细胞长满支架表面 ,且保持良好的功能状态。

关键词：雪旺细胞人胚人工神经支架组织工程功能状态法能构建包埋聚羟基乙酸

Adaptive-basis decomposition-based low-rank network for efficient non-uniform motion deblurring

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Optoelectronics Letters 2025年第1期21卷 43-50页

作者： chen Lei XIONG Qingbo ZHANG wei LI Runde School of Software Henan University School of Applied Technology China University of Labor Relations

In this study, we present a unified sparsity-driven framework that significantly enhances motion deblurring performance by integrating two key components: a custom-designed dataset and a low-rank module(LRM). This framework leverages the inherent sparsity of per-pixel blur kernels to bolster both deblurring accuracy and model interpretability. Firstly, we propose an adaptive-basis decomposition-based deblurring(ADD) approach, which constructs a tailored training dataset to enhance the generalization capacity of the deblurring network. The ADD framework adaptively decomposes motion blur into sparse basis elements, effectively addressing the intricacies associated with non-uniform blurs. Secondly, an LRM is proposed to improve the interpretability of deblurring models as a plug-and-play module, primarily designed to identify and harness the intrinsic sparse features in sharp images. A series of ablation studies have been conducted to substantiate the synergistic advantages of combining the proposed ADD with the LRM for overall improvement in deblurring efficacy. Subsequently, we empirically demonstrate through rigorous experimentation that incorporating the LRM into an existing Uformer network leads to substantial enhancement in reconstruction performance. This integration yields a sparsity-guided low-rank network(SGLRN). Operating under the overarching principle of sparsity, SGLRN consistently outperforms state-of-the-art methods across multiple standard deblurring benchmarks. Comprehensive experimental results, assessed through quantitative metrics and qualitative visual evaluations, provide compelling evidence of its effectiveness. The overall deblurring results are available at Google Drive.

关键词： Image enhancement

Depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 335-345页

作者： Feng Zhang chenyang Zhang Linlin Wu wei Sun Hongliang Zhang Jianhua chen Yong Pei Songjiang Li Engineering Research Center of Ministry of Education for Carbon Emission Reduction in Metal Resource Exploitation and Utilization Hunan International Joint Research Center for Efficient and Clean Utilization of Critical Metal Mineral ResourcesSchool of Minerals Processing and BioengineeringCentral South UniversityChangsha 410083China State Key Laboratory of Mineral Processing Beijing General Research Institute of Mining&MetallurgyBeijing 100160China Hunan Provincial Key Laboratory of Micro&Nano Materials Interfaces Science College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China School of Resources Environment and MaterialsGuangxi UniversityNanning 530004China Department of Chemistry Xiangtan UniversityXiangtan 411105China China Railway Resource Group Co.Ltd Beijing 102300China

The depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite still lacked in-depth ***,the depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite was further systematically investigated with experiments and density functional theory(DFT)*** X-ray photoelectric spectroscopy(XPS)results,DFT calculation results,and frontier molecular orbital analysis indicated that sulfite ions were difficult to be adsorbed on sphalerite surface,suggesting that sulfite ions achieved depression effects on sphalerite through other non-adsorption ***,the oxygen content in the surface of sphalerite treated with sulfite ions in creased,which enhanced the hydrophilicity of the sphalerite and further increased the difference in hydrophilicity between sphalerite and ***,sulfite ions were chelated with lead ions to form PbSO_(3)in *** hydrophilic PbSO_(3)was more easily adsorbed on sphalerite than *** interaction between sulfite ions and lead ions could effectively inhibit the activation of *** addition the UV spectrum showed that after adding sulfite ions,the peak of perxanthate in the sphalerite treated xanthate solution was significantly stronger than that in the galena with xanthate solution,indicating that xanthate interacted more readily with sulfite ions and oxygen mo lecules within the sphalerite system,leading to the formation of ***,sulfite ions hardly depressed the flotation of ga lena and could promote the flotation of galena to some *** study deepened the understanding of the depression mechanism o sulfite ions on sphalerite and Pb^(2+)activated sphalerite.

关键词： sphalerite galena sulfite ion density functional theory depression mechanism

Gut microbiota-astrocyte axis: new insights into age-related cognitive decline

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Neural Regeneration Research 2025年第4期20卷 990-1008页

作者： Lan Zhang Jingge wei Xilei Liu Dai Li Xiaoqi Pang Fanglian chen Hailong Cao Ping Lei Haihe Laboratory of Cell Ecosystem Department of GeriatricsTianjin Medical University General HospitalTianjinChina Tianjin Geriatrics Institute Tianjin Medical University General HospitalTianjinChina Department of Gastroenterology and Hepatology Tianjin Medical University General HospitalNational Key Clinical SpecialtyTianjin Institute of Digestive DiseasesTianjin Key Laboratory of Digestive DiseasesTianjinChina Department of Urology Tianjin Medical University General HospitalTianjinChina Tianjin Neurological Institution Tianjin Medical University General HospitalTianjinChina

With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent *** is considered the main risk factor for cognitive decline and acts through alterations in the composition of the gut microbiota,microbial metabolites,and the functions of *** microbiota–gut–brain axis has been the focus of multiple studies and is closely associated with cognitive *** article provides a comprehensive review of the specific changes that occur in the composition of the gut microbiota and microbial metabolites in older individuals and discusses how the aging of astrocytes and reactive astrocytosis are closely related to age-related cognitive decline and neurodegenerative *** article also summarizes the gut microbiota components that affect astrocyte function,mainly through the vagus nerve,immune responses,circadian rhythms,and microbial ***,this article summarizes the mechanism by which the gut microbiota–astrocyte axis plays a role in Alzheimer’s and Parkinson’s *** findings have revealed the critical role of the microbiota–astrocyte axis in age-related cognitive decline,aiding in a deeper understanding of potential gut microbiome-based adjuvant therapy strategies for this condition.

关键词： age aging Alzheimer’s disease astrocytes cognitive decline dementia gut microbiota gut–brain axis microbial metabolites neuroinflammation Parkinson’s disease

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基于感兴趣区域提取的行人检测

计算机工程与设计 2016年第11期37卷 3035-3039页

作者：靳培飞周莉刘健戈志伟陈杰中国科学院微电子研究所北京100029

为能在单目图像中快速准确地检测出行人,提出一种基于ROI提取的行人检测算法。根据待检测图像的边缘信息提取所有可能含有行人的区域,用区域的中心点代表该区域;基于这些中心点,根据行人在图像中固有的特点,确定行人ROI区域;对该ROI区... 详细信息

为能在单目图像中快速准确地检测出行人,提出一种基于ROI提取的行人检测算法。根据待检测图像的边缘信息提取所有可能含有行人的区域,用区域的中心点代表该区域;基于这些中心点,根据行人在图像中固有的特点,确定行人ROI区域;对该ROI区域进行行人的检测。在INRIA测试集上的测试结果表明,该算法在误检率较低、检测速度较高的情况下,检测率达到95%以上,可以用于实时行人检测系统。

关键词：行人检测感兴趣区域分类器积分通道特征检测率

From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua Lu Jun Shen Xin Zhang Lingcong Chao Liang chen Ding Zhang Tao wei Shoudong Xu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added

Synthesis of 2-Hydroxy-2-oxo-1,4,2-benzoxazaphosphinanes

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Synthesis of 2-Hydroxy-2-oxo-1,4,2-benzoxazaphosphinanes

联合瓣膜置换术后急性肾损伤发生的相关危险因素研究

第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会

作者： WANG, Bin MIAO, zhi-wei HUANG, You chen, Ru-Yu State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China

α-Aminophosphonic acids serve as important analogs of α-amino carboxylic acids in biological systems such as peptides and proteins. Their utilities as enzyme inhibitors, antibiotics, pharmacological agents and many other applications have attracted chemists' interests for a long time.A study on the synthesis of the novel cyclic α-aminophosphonates,2-hydroxy-2-oxo-1,4,2-benzoxazaphosphinanes 5a-d has been carried out. As shown in Scheme

关键词： Taylor Synthesis of 2-Hydroxy-2-oxo-1,4,2-benzoxazaphosphinanes NMR

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中国体外循环杂志 2017年第3期15卷 148-152页

作者：张慧张涛元王淼支伟伟陈伟第四军医大学第一附属医院麻醉科西安710032 第四军医大学第一附属医院心脏外科西安710032 西北妇女儿童医院儿外科

目的研究主动脉瓣+二尖瓣联合瓣膜置换术后急性肾损伤(AKI)的发生情况及其相关危险因素。方法采用回顾性研究。收集本院心外科2011年5月1日至2013年6月30日期间行体外循环下主动脉瓣+二尖瓣联合瓣膜置换术患者400例的临床资料,采用多因... 详细信息

目的研究主动脉瓣+二尖瓣联合瓣膜置换术后急性肾损伤(AKI)的发生情况及其相关危险因素。方法采用回顾性研究。收集本院心外科2011年5月1日至2013年6月30日期间行体外循环下主动脉瓣+二尖瓣联合瓣膜置换术患者400例的临床资料,采用多因素回归方法筛选出该类手术患者术后发生AKI的危险因素。AKI诊断标准为48 h内血清肌酐水平(Scr)上升≥26.4μmol/L,或较基础值增加≥50%,和(或)尿量<0.5 ml/(kg·h)达6 h。结果 400例二尖瓣+主动脉瓣联合瓣膜置换手术患者术后AKI发病率为76%,其中11例(2.75%)需要肾脏替代疗法。单因素分析结果显示年龄、性别、体重指数、术前舒张末容积、基础肾小球滤过率(eGFR)、术前合并高血压、手术时间以及体外循环时间在AKI组和非AKI组具有明显差异。多因素非条件Logistic回归分析表明,年龄增加、男性、体重指数增加、基础eGFR<60 ml/(min·1.73 m^2)以及术前合并高血压是联合瓣膜置换术后AKI的独立危险因素,OR值分别为1.66、2.38、1.15、2.12和2.65。结论 AKI是联合瓣膜置换手术后最常见的严重并发症。高龄、男性、体重指数增加、基础eGFR<60ml/(min·1.73 m^2)以及术前合并高血压是联合瓣膜置换术后发生AKI的独立危险因素。针对AKI及其不良效应的预防和治疗策略是以后研究的重点。

关键词：急性肾损伤联合瓣膜置换术危险因素回顾性研究

A Simple Method for Synthesis of 2-phenyl N,N-Bis (2-chloroethyl)-N'-(4-methylbenzene-sulfonamino)ethyl-phosphorodia midate

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A Simple Method for Synthesis of 2-phenyl N,N-Bis (2-chloroe...