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ImSpiRE: image feature-aided spatial resolution enhancement method

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Science China Life Sciences 2024年

作者： Yuwei Hua Yizhi Zhang zhenming guo Shan Bian Yong Zhang State Key Laboratory of Cardiovascular Diseases and Medical Innovation Center Institute for Regenerative Medicine Department of Neurosurgery Shanghai East Hospital Shanghai Key Laboratory of Signaling and Disease Research Frontier Science Center for Stem Cell Research School of Life Sciences and Technology Tongji University

The resolution of most spatially resolved transcriptomic technologies usually cannot attain the single-cell level, limiting their applications in biological discoveries. Here, we introduce ImSpiRE, an image feature-aided spatial resolution enhancement method for in situ capturing spatial transcriptome. Taking the information stored in histological images, ImSpiRE solves an optimal transport problem to redistribute the expression profiles of spots to construct new transcriptional profiles with enhanced resolution, together with extending the gene expression profiles into unmeasured regions. Applications to multiple datasets confirm that ImSpiRE can enhance spatial resolution to the subspot level while contributing to the discovery of tissue domains, signaling communication patterns, and spatiotemporal characterization.

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机房基础设施监控系统的应用与实践

电视技术 2024年第1期48卷 190-193页

作者：郭振明南京市浦口广电网络有限公司江苏南京211800

近年来,随着网络与数字技术的不断发展,有线电视媒体迎来新的挑战。为了主动适应媒体深度融合、“全国一网”和广电5G一体化发展新要求,保障安全播出、安全生产的任务,机房的稳定高效运行至关重要。基础设施监控系统管理各级机房设备的... 详细信息

近年来,随着网络与数字技术的不断发展,有线电视媒体迎来新的挑战。为了主动适应媒体深度融合、“全国一网”和广电5G一体化发展新要求,保障安全播出、安全生产的任务,机房的稳定高效运行至关重要。基础设施监控系统管理各级机房设备的工作状态,为机房的稳定运行提供了可靠的保障,实现了机房管理更简单、方便、及时的目标。基于此,阐述机房基础设施监控系统的的建设意义,介绍机房基础设施监控系统的应用与实践。

关键词：网点机房监控系统安防基础设施

In situ Preparation and Visible-light-driven Photocatalytic Degradation Performance of Nano 3C-SiC@Multilayer Graphene Oxide Heterostructure

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Chemical Research in Chinese Universities 2024年第3期40卷 536-547页

作者： YANG Xiaodan guo Ziqi XU Yichen LI Ziliang ZHOU Yangtao YANG zhenming ZHOU Zishuai GAO Yong ZHANG Jinsong Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016P.R.China Nano Science and Technology Institute University of Science and Technology of ChinaSuzhou 215123P.R.China Shenyang SCIENCREAT Chemicals Co. Ltd.Shenyang 110144P.R.China School of Materials Science and Engineering Northeastern UniversityShenyang 110819P.R.China

Nano 3C-SiC@multilayer graphene oxide(NS@MGO)heterostructure was in situ prepared by carbothermal reduction of pyrolyzed precursor composed of highly dispersed cured phenolic resin and silicon dioxide derived from tetraethyl *** heterojunction interface,number of layers of MGO,and defect content in graphene are the three most important factors for promoting photocatalytic *** contact between 3C-SiC nanograins and MGO layers facilitates the photogenerated electrons to migrate across the heterojunction interface and avoid the formation of SiO_(2) nanolayers on the surface of SiC *** number of MGO layers is supposed to be less than ten instead of over-thick *** concentrations of oxygenated components,considered the defect contents,decrease with the increase of sintering temperature for NS@MGO 0.175-T-150,and relative carbon content in the multilayer graphene *** to the heterostructures,properties,and photocatalytic reaction performance of the NS@MGO materials,the highest photocatalytic kinetic rate constant of 0.00891/min for NS@MGO 0.175-1500-150 shows that the significant enhancement in photocatalytic degradation activity under visible light(>420 nm)irradiation is ascribed to the advantageous synergistic effects between the nano 3C-SiC particles and the direct contact multilayer graphene oxide with appropriate layers and sufficient oxygen content of 3.51%(atomic fraction)in MGO.

关键词： Photocatalysis Multilayer graphene oxide Nano 3C-SiC Visiblelight degradation

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混沌优化用于电力系统静态负荷模型参数辨识

电力系统自动化 2000年第13期24卷 27-30页

作者：唐巍郭镇明李殿璞哈尔滨工程大学哈尔滨150001

提出了一种应用混沌优化方法进行电力系统静态负荷模型参数辨识的新策略。混沌优化方法利用混沌变量的随机性、规律性、遍历性寻优 ,能够克服传统的基于梯度寻优的辨识方法容易陷入局部极小点的不足 ,而且方法简单、快速、易于掌握。

关键词：静态负荷模型混沌优化参数辨识电力系统

An analysis of the transcriptional landscape in hypoxia-treated primary nucleus pulposus cells

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Genes & Diseases 2024年第2期11卷 558-560页

作者： Zhicai Peng Zhuo Wang Shuaichi guo Bing Tan Ruichao Cao Shengqiang Cheng Jun Chen Chunwang Xie Dehong Mao zhenming Hu Department of Orthopaedics Yongchuan Traditional Chinese Medicine Hospital of ChongqingChongqing 402160China Department of Orthopaedic Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China Department of Spine Surgery The Third Hospital of MianyangSichuan Mental Health CenterMianyangSichuan 621000China

Intervertebral disc degeneration(IDD)is the main cause of lower back *** back pain places a huge burden on society,and all current treatments for IDD cannot restore the original function of the intervertebral *** new treatments for IDD requires clarifying the mechanisms of *** hypoxia is an important feature of the nucleus pulposus because of its special anatomical *** RNA sequencing(RNA-seq),we obtained the whole transcriptome of nucleus pulposus cells(NPCs)under hypoxia and hypoxia-inducible factor(HIF1A)*** demonstrated possible effects of oxygen concentration and HIF1A on *** addition,our results showed that hypoxia can affect lipid metabolism in NPCs.

关键词： structure metabolism degeneration

Prediction of adolescent subjective well being: A machine learning approach

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General Psychiatry 2019年第5期32卷 261-268页

作者： Naixin Zhang Chuanxin Liu Zhixuan Chen Lin An Decheng Ren Fan Yuan Ruixue Yuan Lei Ji Yan Bi zhenming guo Gaini Ma Fei Xu Fengping Yang Liping Zhu Gabirel Robert Yifeng Xu Lin He Bo Bai Tao Yu Guang He Bio-X Institutes Shanghai Jiao Tong UniversityShanghaiChina Shanghai Key Laboratory of Psychotic Disorders and Brain Science and Technology Research CenterShanghai Jiao Tong UniversityShanghaiChina School of Mental Health Jining Medical UniversityShandongChina Shanghai Center for Women and Children's Health ShanghaiChina Department of psychiatry Medical University of RennesRennesFrance Institute of Neurobiology Jining Medical UniversityShandongChina

Background Subjective well-being(SWB),also known as happiness,plays an important role in evaluating both mental and physical *** deserve specific attention because they are under a great variety of stresses and are at risk for mental disorders during *** The present paper aims to predict undergraduate students1 SWB by machine learning *** Gradient Boosting Classifier which was an innovative yet validated machine learning approach was used to analyse data from 10518 Chinese *** online survey included 298 factors such as depression and *** control procedure was used to minimise biases due to online survey *** applied feature selection to achieve the balance between optimal prediction and result *** The top 20 happiness risks and protective factors were finally brought into the predicting *** 90%individuals'SWB can be predicted correctly,and the sensitivity and specificity were about 92%and 90%,*** This result identifies at-risk individuals according to new characteristics and established the foundation for adolescent prevention strategies.

关键词： prevention protective specificity

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汉语美学语境中的神学美学之思

厦门广播电视大学学报 2008年第2期11卷 65-67页

作者：郭珍明新疆艺术学院新疆乌鲁木齐830049

回眸自王国维以来的百年汉语美学历程,神学美学的叙述在三次美学热中的缺席耐人寻味。本文通过对百年汉语美学历程的反思与追溯,初步揭示神学美学在汉语学界缺席多年的历史与文化困境,进一步探讨神学美学在当今汉语美学语境中生成的现... 详细信息

回眸自王国维以来的百年汉语美学历程,神学美学的叙述在三次美学热中的缺席耐人寻味。本文通过对百年汉语美学历程的反思与追溯,初步揭示神学美学在汉语学界缺席多年的历史与文化困境,进一步探讨神学美学在当今汉语美学语境中生成的现实与前景,并认为神学美学将会成为汉语美学叙事的重要构成部分。

关键词：汉语美学美学热神性神学美学

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玩世现实主义的文化取向

新疆艺术学院学报 2008年第4期6卷 46-50页

作者：郭珍明新疆艺术学院美术学院新疆乌鲁木齐830049

玩世现实主义是中国20世纪90年代一种重要的艺术现象,是中国当代艺术在新的历史文化情境中自然变异的结果。它以玩世不恭、嘲讽调侃的艺术风格表达了新生代艺术家对当下生存状态的近距离关注,以及对政治意识形态和商业意识形态的双重消... 详细信息

玩世现实主义是中国20世纪90年代一种重要的艺术现象,是中国当代艺术在新的历史文化情境中自然变异的结果。它以玩世不恭、嘲讽调侃的艺术风格表达了新生代艺术家对当下生存状态的近距离关注,以及对政治意识形态和商业意识形态的双重消解。本文揭示了玩世现实主义的文化立场和现实诉求,并力图作出客观、中肯的学术评价。

关键词：玩世现实主义文化取向新生代

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高校社团管理系统的设计与实现

电脑与电信 2017年第1期 28-30页

作者：董彩华梁敏健郭振铭江苏海事职业技术学院信息工程学院江苏南京211100

为了提高社团管理人员的工作效率和管理水平,采用软件工程学的理念,设计一个基于B/S模式的包含社团管理、系统管理、成员管理、数据管理等管理模块的社团管理系统,该系统采用***技术以及SQL Server数据库开发语言,经过测试验证基本满足... 详细信息

为了提高社团管理人员的工作效率和管理水平,采用软件工程学的理念,设计一个基于B/S模式的包含社团管理、系统管理、成员管理、数据管理等管理模块的社团管理系统,该系统采用***技术以及SQL Server数据库开发语言,经过测试验证基本满足了功能需求。

关键词： VS2010 数据库社团管理数据管理