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大肠杆菌启动子特征元件对启动子识别的影响

北京工业大学学报 2005年第2期31卷 126-129页

作者：冉令华阮晓钢北京工业大学电子信息与控制工程学院北京100022

为了进一步研究大肠杆菌启动子的识别算法,根据大肠杆菌基因分子生物学有关理论与统计事实,对大肠杆菌启动子特征元件进行了研究.从启动子样本中选取不同的保守序列,采用2种神经网络结构.分别分析了启动子特征元件对识别的影响.研究发现... 详细信息

为了进一步研究大肠杆菌启动子的识别算法,根据大肠杆菌基因分子生物学有关理论与统计事实,对大肠杆菌启动子特征元件进行了研究.从启动子样本中选取不同的保守序列,采用2种神经网络结构.分别分析了启动子特征元件对识别的影响.研究发现.包含-10和-35区2个显著保守序列元件及其他几个非显著序列元件时,正样本和负样本的识别率最高,达到77.67％和88.45％.实验结果为进一步研究启动子的特征提取和识别算法提供了参考.

关键词：神经网络大肠杆菌启动子

高新技术企业资质认定与上市企业股价崩盘风险——基于产业政策微观实施的证据

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财经论丛 2021年第6期 78-89页

作者：孙刚郑琦浙江财经大学东方学院浙江嘉兴314408 长沙理工大学经济与管理学院湖南长沙410114

文章聚焦于“产业政策要准”这一核心问题,分析了我国高科技产业政策微观实施与资本市场信息风险的关系。文章将“高新技术企业”资质认定视为实施高科技产业政策的重要机制,研究发现获得“高新技术企业”资质认定的企业其股价崩盘风险... 详细信息

文章聚焦于“产业政策要准”这一核心问题,分析了我国高科技产业政策微观实施与资本市场信息风险的关系。文章将“高新技术企业”资质认定视为实施高科技产业政策的重要机制,研究发现获得“高新技术企业”资质认定的企业其股价崩盘风险显著降低。围绕两者间的实现机制及其价值效应,文章进一步拓展研究发现,获得“高新技术企业”资质认定后企业盈利操纵性部分显著减少,盈利稳定性更高,股价波动同步性程度更低,证券分析师盈利预测更精准,企业价值显著提升。文章从我国产业政策微观实施的视角,解释了上市企业股价崩盘风险的形成机制,表明国家宏观政策的微观实施具有抑制信息“失真”和信息“扭曲”的作用,对从产业政策执行视角厘清政治因素与资本市场信息风险定价的形成途径具有借鉴价值。

关键词：产业政策高新技术企业认定股价崩盘风险信息风险

Immediate Effect of Electro-acupuncture on Endometrial Blood Flow in Patients with Recurrent Implantation Failure:A Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第4期30卷 291-298页

作者： LAI Yuan-yuan LIU Li-ying WU Yong-na HUANG Lei zheng xiao-yan GAN Di YU Si-yi ZHONG Ying LIANG Fan-rong ZHOU Ying YANG Jie Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu(610032)China Sichuan Jinxin Xi'nan Women's and Children's Hospital Chengdu(610032)China Yuan TCM Wellness Pte.Ltd.(999002) Pulse TCM SingaporeSingapore

Objective To investigate the immediate effects of electro-acupuncture(EA)on endometrial blood flow among recurrent implantation failure(RIF)*** Eighty RIF patients,enrolled from March 2022 to December 2022,were randomly allocated into either the EA group(40 cases)or the waiting-list(WL)group(40 cases)by using a random number *** EA group underwent acupuncture at points of Shenting(GV 24),Baihui(GV 4),Benshen(GB 13),bilateral Zigong(EX-CA 1),Huangshu(KI 16),Sanyinjiao(SP 6)and Xuehai(SP10),and electric acupuncture apparatus was connected to EX-CA 1,KI 16,SP 6,and SP 10 with disperse-dense waves at 4/20 Hz frequencies for 30 min after transvaginal ultrasound,while the WL group received no *** primary outcome measured was the endometrial volume blood *** secondary outcomes included the bilateral uterine artery index,endometrial volume,endometrial blood flow type,vascular distribution index(VI^(MV))for endometrial and ovary,clinical pregnancy rate,and embryo implantation *** In the EA group,there was a notable decrease in the bilateral pulsatility index and a significant improvement in the endometrial blood flow type post-EA(P0.05).Besides,no adverse events related to EA were *** EA can promptly ameliorate VI^(MV) for the endometrial and right ovary,and endometrial blood flow *** randomized controlled trials are warranted to investigate the long-term effects of EA on blood flow of RIF patients and its implications for pregnancy outcomes.(Trial registration ***2200057377

关键词： electro-acupuncture recurrent implantation failure transvaginal ultrasound endometrial receptivityanalysis randomized controlledtrial

Microbial Community Changes Along a Land-Use Gradient of Desert Soil Origin

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Pedosphere 2012年第5期22卷 593-603页

作者： WANG Bao-Zhan ZHANG Cai-Xia LIU Ji-Liang ZENG xiao-Wei LI Feng-Rui WU Yu-Cheng LIN Xian-Gui XIONG zheng-Qin XU Jian JIA Zhong-Jun Institute of Soil Science Chinese Academy of SciencesNanjing 210008(China) Nanjing Agricultural University Nanjing 210095(China) Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of SciencesLanzhou 730000(China) Qingdao Institute of BioEnergy and Bioprocess Technology Chinese Academy of SciencesQingdao 266101(China)

Soil harbors remarkably stabilize bacterial communities at the phylum level. However, no two soils have exactly the same structure of bacterial phyla. The structure of microbial community is strongly influenced by the type of land-use through changes in soil attributes. Using high-throughput pyrosequencing and quantitative polymerase chain reaction techniques, soil microbial community structures were investigated along a land-use gradient of 100- and 27-year farmlands, a 33-year Pinus forest, a 28-year poplar forest, and a 21-year shrubland, as well as a native desert from which all cultivated systems were converted. The results revealed that the dominant phylotypes in the native soil comprised primarily of Alphaproteobacteria, Actinobacteria, Bacteroidetes, and Firmicutes, accounting for 〉 71.4% of the total bacterial 16S rRNA sequence reads. Changes in land-use led to a significant decrease in these dominant phylotypes down to 33.4%. In contrast, the phylotypes with low abundance, such as Acidobaeteria, Chloroflexi, Nitrospira, and Gammaproteobaeteria, increased sharply from 4.5%-5.9% in the native soil to 20.9% 30.2% of the total 16S rRNA gene sequences in the cultivated soils except for the soil from the shrubland. These contrasting changes in the major taxa appear to be correlated with the changes in soil attributes. For instance, bacterial and archaeal amoA genes were found to be 960- and 3 800-fold more abundant in the soil from the 100-year farmland than the native soil. The changes in numerically less dominant nitrifying phylotypes are consistent with soil inorganic nitrogen dynamics. Quantification of the 16S rRNA genes demonstrated that bacteria and archaea were about two to three orders of magnitude more abundant in the cultivated soil than in the native soil. Hence, land-use type affects the soil bacterial community structure, which has profound consequences on ecosystem function.

关键词： amoA ecosystem functions land-use type polymerase chain reaction pyrosequencing

论物流专业创新人才培养——以扬州地方高校为例

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物流技术 2012年第11期31卷 478-480页

作者：霍正刚扬州大学水利科学与工程学院江苏扬州225127

探讨了物流创新人才概念以及培养物流创新人才的意义,重点分析了当前部分高校在物流创新人才培养中存在的培养理念和目标不明确等问题;最后,针对存在的问题提出相应改进措施,为我国建设创新型国家培养大批物流创新人才。

关键词：物流创新人才人才培养

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稳态温度场中螺旋位错与圆弧裂纹的交互作用

机械强度 2007年第5期29卷 779-783页

作者：肖万伸魏刚湖南大学工程力学系长沙410082

研究压电材料在稳态温度场下螺旋位错与圆弧裂纹的交互作用。综合运用复变函数分区全纯理论、解析函数奇性主部分析方法、解析延拓原理、Cauchy型积分以及Riemann边值问题求解方法,导出各复势函数之间的解析关系,进一步得到特殊情况下... 详细信息

研究压电材料在稳态温度场下螺旋位错与圆弧裂纹的交互作用。综合运用复变函数分区全纯理论、解析函数奇性主部分析方法、解析延拓原理、Cauchy型积分以及Riemann边值问题求解方法,导出各复势函数之间的解析关系,进一步得到特殊情况下所讨论问题的封闭解,并解出像力随温度梯度和位错位置变化的表达式。数值分析结果表明,温度梯度越大,像力变化越明显。

关键词：压电材料螺旋位错圆弧裂纹像力

Urban structure and the risk of influenza A(H1N1) outbreaks in municipal districts

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Chinese Science Bulletin 2014年第5期59卷 554-562页

作者： Hong xiao xiaoling Lin Gerardo Chowell Cunrui Huang Lidong Gao Biyun Chen zheng Wang Liang Zhou Xinguang He Haining Liu Xixing Zhang Huisuo Yang College of Resources and Environment Science Hunan Normal University Mathematical Computational and Modeling Sciences CenterSchool of Human Evolution and Social Change Arizona State University Division of International Epidemiology and Population Studies Fogarty International Center National Institutes of Health Centre for Environment and Population Health School of Environment Griffith University Hunan Provincial Center for Disease Control and Prevention Department of Respiratory and Critical Care Medicine Beijing Institute of Respiratory Medicine Beijing Chaoyang Hospital Affiliated to Capital Medical University Changsha Municipal Center for Disease Prevention and Control Center for Disease Control and Prevention of Beijing Military Region

Changsha was one of the most affected areas during the 2009 A(H1N1)influenza pandemic in ***,we analyze the spatial–temporal dynamics of the 2009 pandemic across Changsha municipal districts,evaluate the relationship between case incidence and the local urban spatial structure and predict high-risk areas of influenza A(H1N1).We obtained epidemiological data on all cases of influenza A(H1N1)reported across municipal districts in Changsha during period May 2009–December 2010 and data on population density and basic geographic characteristics for 239 primary schools,97 middle schools,347 universities,96 malls and markets,674 business districts and 121 ***–temporal K functions,proximity models and logistic regression were used to analyze the spatial distribution pattern of influenza A(H1N1)incidence and the association between influenza A(H1N1)cases and spatial risk factors and predict the infection *** found that the 2009 influenza A(H1N1)was driven by a transmission wave from the center of the study area to surrounding areas and reported cases increased significantly after September *** also found that the distribution of influenza A(H1N1)cases was associated with population density and the presence of nearest public places,especially universities(OR=10.166).The final predictive risk map based on the multivariate logistic analysis showed high-risk areas concentrated in the center areas of the study area associated with high population *** findings support the identification of spatial risk factors and highrisk areas to guide the prioritization of preventive and mitigation efforts against future influenza pandemics.

关键词：风险图流感甲型城市结构 Logistic回归分析 logistic回归城市空间结构爆发

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20世纪50年代我国高等教育部的历史考察

高等教育研究 2019年第5期40卷 84-91页

作者：郑刚徐丹华中师范大学教育学院

高等教育部是新中国成立后独立设置的高等教育行政管理机构。在20世纪50年代,高等教育部承担领导全国高等教育及中等职业教育的职能。高等教育部推动了教育行政管理体制的改革,建立起条块分明的管理体制和校、系、教研室三级联动的组织... 详细信息

高等教育部是新中国成立后独立设置的高等教育行政管理机构。在20世纪50年代,高等教育部承担领导全国高等教育及中等职业教育的职能。高等教育部推动了教育行政管理体制的改革,建立起条块分明的管理体制和校、系、教研室三级联动的组织体系;领导了两次院系调整的实施,扭转了高校区域分布不均、系科设置错乱的状况;推进了高校教学改革开展,建立起社会主义教学制度;将中等职业纳入管理体系,弥补了工业建设对专业人才的巨大需求。高等教育部的改革经验与兴废曲折,折射出政治经济因素与教育规律的联动关系,反映出基础教育与高等教育的资源分配问题。

关键词：高等教育部教育行政管理体制院系调整教学改革

基于云图-条带法的概率地震需求分析与地震易损性分析

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工程力学 2016年第6期33卷 68-76页

作者：于晓辉吕大刚哈尔滨工业大学结构工程灾变与控制教育部重点实验室哈尔滨150090

提出一种概率地震需求分析的云图-条带法。该方法通过引入经验地震易损性分析中的数据处理方法,解决传统云图法无法处理海量非线性时程分析结果的局限。为说明该文提出方法,选取100条地震动作为输入,针对23个钢筋混凝土框架结构进行了... 详细信息

提出一种概率地震需求分析的云图-条带法。该方法通过引入经验地震易损性分析中的数据处理方法,解决传统云图法无法处理海量非线性时程分析结果的局限。为说明该文提出方法,选取100条地震动作为输入,针对23个钢筋混凝土框架结构进行了云图法分析。基于所有结构的云图结果,采用云图-条带法建立了群体结构的概率地震需求模型,并计算得到了群体结构的地震易损性。研究表明:云图-条带法可以有效地处理海量非线性时程分析结果,建立较为合理的概率地震需求模型。在输入地震动的强度范围内,群体结构整体发生严重破坏和完全破坏的概率很低,而主要以发生轻微破坏和中等破坏为主。

关键词：云图-条带法云图法条带法概率地震需求地震易损性