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HIV-1 Transmission among Injecting Drug Users is Principally Derived from Local Circulating Strains in Guangxi, China

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Biomedical and Environmental Sciences 2023年第5期36卷 418-430页

作者： CEN Ping LIANG Hua Yue yang Yuan ZHANG Fei yang Shi Xiong MO Ju Cong FENG Yi HUANG Jie Gang NING Chuan Yi HUANG chun Yuan yang Yao LIANG Na LIANG Bing Yu YE Li LIANG Hao Guangxi Key Laboratory of AIDS Prevention and Treatment School of Public HealthGuangxi Medical UniversityNanning 530021GuangxiChina Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry Life Science InstituteGuangxi Medical UniversityNanning 530021GuangxiChina Nanning Center for Disease Control and Prevention Nanning 530023GuangxiChina State Key Laboratory of Infectious Disease Prevention and Control(SKLID) Chinese Center for Disease Control and Prevention(China CDC)Collaborative Center for Diagnosis and Treatment of Infectious DiseaseBeijing 102206China

Objective The mode of human immunodeficiency virus(HIV) transmission via injection drug use(IDU)still exists, and the recent shift in IDU-related transmission of HIV infection is largely unknown. The purpose of this study was to analyze the spatiotemporal sources and dynamics of HIV-1 transmission through IDU in *** We performed a molecular epidemiological investigation of infections across Guangxi from2009 to 2019. Phylogenetic and Bayesian time-geographic analyses of HIV-1 sequences were performed to confirm the characteristics of transmission between IDUs in combination with epidemiological *** Among the 535 subjects, CRF08_BC(57.4%), CRF01_AE(28.4%), and CRF07_BC(10.7%) were the top 3 HIV strains;72.6% of infections were linked to other provinces in the transmission network;93.6% of sequence-transmitted strains were locally endemic, with the rest coming from other provinces,predominantly Guangdong and Yunnan;92.1% of the HIV transmission among people who inject drugs tended to be transmitted between HIV-positive *** HIV recombinants were high diversity, and circulating local strains were the transmission sources among IDUs in Guangxi. However, there were still cases of IDUs linked to other *** of traditional prevention strategies should be expanded, and inter-provincial collaboration between Guangxi, Yunnan, and Guangdong provinces should be strengthened.

关键词： HIV-1 Injection drug use Transmission Strain source Phylogenetics

一种适用于模块化多电平换流器的多阶段模型预测控制方法

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哈尔滨理工大学学报 2024年第2期29卷 101-109页

作者：张景明仇成王骏吴评刘春国网上海市电力公司经济技术研究院上海200233 上海电力大学电气工程学院上海200090

模块化多电平换流器(MMC)具有可扩展性强、输出电能质量高等优点,在电能传输领域受到了广泛的关注。针对传统模型预测控制权重因子设计复杂、桥臂环流谐波分量大等问题,文中提出了一种多阶段模型预测控制(MSMPC)方法。所提出MSMPC方法... 详细信息

模块化多电平换流器(MMC)具有可扩展性强、输出电能质量高等优点,在电能传输领域受到了广泛的关注。针对传统模型预测控制权重因子设计复杂、桥臂环流谐波分量大等问题,文中提出了一种多阶段模型预测控制(MSMPC)方法。所提出MSMPC方法包括三个阶段:1)第一阶段获得输出电流跟踪的参考控制选项,实现交流电流控制;2)第二阶段通过引入两个环流因子来计算前阶段控制中上、下桥臂的子模块(SMs)的最优数量;3)第三阶段提出一种子模块预测电压分组排序方法,可有效减少电压排序次数和降低开关频率。与传统的MPC方法相比,所提出的MSMPC方法避免了权重因子设计,提高了环流抑制的性能,同时降低了控制器的计算量。通过仿真和实验结果验证了所提MSMPC方法的有效性。

关键词：模块化多电平转换器多阶段模型预测控制方法环流因子电压分组排序环流抑制

悬浮物特征对砂加载混凝沉淀处理高悬浮矿井水实验的影响

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科学技术与工程 2024年第2期24卷 871-877页

作者：杨小勇张兆李甲李庭邸卫猛王雨晨卜奕丹郝春明陕西小保当矿业有限公司榆林719302 中煤(北京)环保股份有限公司北京100013 中国矿业大学(北京)化学与环境工程学院北京100083 华北科技学院化工安全学院三河065201

高悬浮物矿井水高效快速处理是解决西部六省区煤炭资源化合理利用的关键。关于原水中悬浮物特征对石英砂加载混凝沉淀效果的影响则很少有系统的研究,影响机制也不清晰。为此,选用石英砂加载混凝处理陕西小保当煤矿典型高悬浮矿井水为研... 详细信息

高悬浮物矿井水高效快速处理是解决西部六省区煤炭资源化合理利用的关键。关于原水中悬浮物特征对石英砂加载混凝沉淀效果的影响则很少有系统的研究,影响机制也不清晰。为此,选用石英砂加载混凝处理陕西小保当煤矿典型高悬浮矿井水为研究对象,分析矿井水中悬浮物的粒径、煤岩比和初始负荷大小对石英砂加载混凝处理高悬浮物矿井水效率的影响。矿井水中悬浮物的粒径、煤岩比和初始负荷大小对石英砂加载混凝处理高悬浮物矿井水效率和沉降速度的影响明显。通常,混凝沉淀的去除效率和沉降速度随矿井水中悬浮物的粒径而显著升高,但当悬浮物的粒径过低(小于0.075 mm)后,沉降速率和去除效率明显降低。矿井水悬浮物的初始负荷过高(高于10 000 NTU)和过低(低于500 NTU)都会降低混凝去除效率和沉降速度。矿井水悬浮物中煤粉质量含量越高,砂加载混凝处理效率越低。该结果为有效提升砂加载混凝工艺的运行成效,缓解中国西部矿区水资源短缺的矛盾,同时对中国煤炭行业的绿色发展和矿区生态文明建设也具有重要的意义。

关键词：石英砂加载混凝沉淀粒径煤岩质量比初始负荷

饲粮添加黄芪复方中草药对育肥猪血清免疫指标及肉品质的影响

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饲料研究 2024年第8期47卷 37-43页

作者：杨祺福徐文思龚叶春刘懿漩马嘉晨王京仁朱金桥彭敬湖南文理学院生命与环境科学学院水产高效健康生产湖南省协同创新中心动物学湖南省高校重点实验室常德市农业生物大分子研究中心湖南常德415000 湖南惠生农业科技开发股份有限公司湖南常德415000

试验旨在研究黄芪复方中草药对育肥猪血清免疫指标、肉品质及肌肉营养成分的影响。选取250头170日龄,体况、体重相近的育肥猪,随机分为5组,每组5个重复,每个重复10头育肥猪。对照组饲喂基础饲粮,试验组分别饲喂添加0.6%、0.8%、1.0%和1... 详细信息

试验旨在研究黄芪复方中草药对育肥猪血清免疫指标、肉品质及肌肉营养成分的影响。选取250头170日龄,体况、体重相近的育肥猪,随机分为5组,每组5个重复,每个重复10头育肥猪。对照组饲喂基础饲粮,试验组分别饲喂添加0.6%、0.8%、1.0%和1.2%黄芪复方中草药(ACM)的饲粮,试验期60 d。结果显示,0.8%ACM组和1.0%ACM组育肥猪血清免疫球蛋白与补体蛋白含量显著高于对照组(P<0.05)。与对照组相比,各试验组肌肉失水率显著降低(P<0.05),肉色红度值显著提高(P<0.05),黄度值显著降低(P<0.05)。与对照组相比,试验组肉中水分含量显著降低(P<0.05),1.0%ACM组肉中粗脂肪含量显著提高(P<0.05),0.8%ACM组和1.2%ACM组肉中粗蛋白含量显著提高(P<0.05)。添加1.2%ACM显著提高了肉中总氨基酸及必需氨基酸的含量(P<0.05),添加0.8%ACM可显著提高肉中多不饱和脂肪酸含量(P<0.05)。研究表明,饲粮添加0.8%~1.0%ACM能够提高育肥猪血清免疫功能,改善猪肉品质。

关键词：黄芪育肥猪免疫功能肉品质

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新能源发电设备接入的电磁暂态仿真研究

自动化技术与应用 2024年第1期43卷 161-165页

作者：刘一民郑少明董鹏卜立之赵青春国家电网有限公司华北分部北京100053 南京南瑞继保电气有限公司江苏南京211102

构建由风力机模型、双馈感应电机模型及传动系统等构成的双馈风力发电机组(DFIG)为新能源发电设备代表,进行考虑新能源发电设备接入的电磁暂态仿真研究,深度剖析DFIG接入后的电网系统平稳运行以及电压跌落状态下的电磁暂态响应。

关键词：新能源发电设备传动系统电磁暂态仿真双馈风力发电 Crowbar保护电路

Semi-solid materials for controlled release drug formulation： current status and future prospects

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Frontiers of Chemical Science and Engineering 2014年第2期8卷 225-232页

作者： Michelle TRAN chun WANG Department of Biomedical Engineering University of Minnesota 7-105 Hasselmo Hall 312 Church Street S.E. Minneapolis MN 55455 USA

Semi-solid materials represent an important category of inactive ingredients （excipients） of pharmaceutical products. Here we review several common semisolid polymers currently used in the controlled release formulations of many drugs. These polymers are selected based on their importance and broad scope of application in FDA-approved drug products and include several polysaccharides （cellulose, starch, chitosan, alginate） and carbomers, a group of mucoadhesive synthetic polymers. Glyceride-based polymers used in self-emulsifying drug delivery systems （SEDDS） will also be discussed for its importance in formulating poorly water-soluble drugs. Unique features and advantages of each type of semi-solid materials are discussed and examples of their use in oral delivery of drugs are provided. Finally, future prospects of developing new and better semi-solid excipients are discussed with the objective of facilitating clinical translation.

关键词： semi-solids polymer excipient controlledrelease drug delivery

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国内外行道树标准比对分析研究

中国标准化 2024年第15期 207-211页

作者：王延洋王本耀朱春玲潘柯良上海市绿化管理指导站上海城市树木生态应用工程技术研究中心上海新宿标准化技术服务中心上海临港共生态经济研究院

行道树是城市绿化系统的主旋律。本文从国际层面、发达国家和国内层面三个维度入手,梳理分析当前各层面开展行道树标准化活动的具体情况,并通过系统比对分析,深入剖析我国目前在开展标准研制、参与国际标准化活动、采用国外先进标准等... 详细信息

行道树是城市绿化系统的主旋律。本文从国际层面、发达国家和国内层面三个维度入手,梳理分析当前各层面开展行道树标准化活动的具体情况,并通过系统比对分析,深入剖析我国目前在开展标准研制、参与国际标准化活动、采用国外先进标准等方面存在的不足,为上海市进一步夯实行道树标准化能力提出相关建议和对策。

关键词：行道树标准比对分析

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Ultra-thin Glass Film Coated with Graphene: A New Material for Spontaneous Emission Enhancement of Quantum Emitter

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Nano-Micro Letters 2015年第3期7卷 261-267页

作者： Lu Sun chun Jiang State Key Laboratory of Advanced Optical Communication System and Networks Shanghai Jiao Tong University

We propose an ultra-thin glass film coated with graphene as a new kind of surrounding material which can greatly enhance spontaneous emission rate(SER) of dipole emitter embedded in it. With properly designed parameters,numerical results show that SER-enhanced factors as high as 1.286 9 106 can be achieved. The influences of glass film thickness and chemical potential/doping level of graphene on spontaneous emission enhancement are also studied in this paper. A comparison is made between graphene and other coating materials such as gold and silver to see their performances in SER enhancement.

关键词： Graphene surface plasmons Graphene plasmonics Quantum electrodynamics Superradiance Subwavelength structures

Warm ischemia time and elevated serum uric acid are associated with metabolic syndrome after liver transplantation with donation after cardiac death

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World Journal of Gastroenterology 2018年第43期24卷 4920-4927页

作者： Liang-Shuo Hu Yi-Chao Chai Jie zheng Jian-Hua Shi chun Zhang Min Tian Yi Lv Bo Wang Ai Jia Department of Hepatobiliary Surgery First Affiliated Hospital of Xi’an Jiaotong University Clinical Research Center First Affiliated Hospital of Xi’an Jiaotong University Department of Gastroenterology First Affiliated Hospital of Xi’an Jiaotong University

AIM To describe the prevalence of posttransplant metabolic syndrome(PTMS) after donation after cardiac death(DCD) liver transplantation(LT) and the pre-and postoperative risk *** One hundred and forty-seven subjects who underwent DCD LT from January 2012 to February 2016 were enrolled in this study. The demographics and the clinical characteristics of pre-and post-transplantation were collected for both recipients and donors. PTMS was defined according to the 2004 Adult Treatment Panel-Ⅲ criteria. All subjects were followed monthly for the initial 6 mo after discharge, and then, every 3 mo for 2 years. The subjects were followed every 6 mo or as required after 2 years *** The prevalence of PTMS after DCD donor orthotopic LT was 20/147(13.6%). Recipient's body mass index(P = 0.024), warm ischemia time(WIT)(P = 0.045), and posttransplant hyperuricemia(P = 0.001) were significantly associated with PTMS. The change in serum uric acid levels in PTMS patients was significantly higher than that in non-PTMS patients(P < 0.001). After the 1 s t mo, the level of serum uric acid of PTMS patients rose continually over a period, while it was unaltered in non-PTMS patients. After transplantation, the level of serum uric acid in PTMS patients was not associated with renal *** PTMS could occur at early stage after DCD LT with growing morbidity with the passage of time. WIT and post-LT hyperuricemia are associated with the prevalence of PTMS. An increased serum uric acid level is highly associated with PTMS and could act as a serum marker in this disease.

关键词： Posttransplant metabolic syndrome Liver transplantation Donation after cardiac death Uric acid Warm ischemia time