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Retrospect and Prospect of Higher Education in Chinese Medicine in Hong Kong,China

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Chinese Journal of Integrative Medicine 2017年第7期23卷 494-495页

作者： zhao zhong-zhen School of Chinese Medicine Hong Kong Baptist UniversityHong Kong SAR China

It has been 16 years since the first courses on Chinese medicine （CM） at Hong Kong Baptist University （HKBU） were *** can be said that the advancement o f CM education is a microcosm of the development of the CM in Hong Kong *** a past course director,I was closely involved with colleagues and students in this unforgettable *** Years of Difficulty Have Laid the Foundation for A Bright Future

关键词： Baptist courses director Bright created advancement curriculum pharmacy Australia earned

Synthesis and Structure of [Cu(OH)_2(H_2O)_2(4-C_5H_4N-COOH)_2]

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Chinese Journal of Structural Chemistry 2001年第6期20卷 478-480页

作者： zhong zhao-En SUN Dao-Feng South China Medical Apparatus Coorporation Ltd. Tonghe TownTongsha Road 13Guangzhou 510515China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouFujian 350002China

The hydrothermal reaction of isonicotinic acid (4-C5H4N-COOH), Cu(ClO4)(2). 6H(2)O and water at 170 degreesC gave the title compound, [Cu(OH)(2)(H2O)(2)(4-C5H4N-COOH)(2)] (1), which was analyzed by single-crystal X-ray diffraction, The complex crystallizes in triclinic space group PY with unit cell parameters: a = 6.337(2), b = 6.894(3), c = 9.178(3). alpha = 99.40(3), beta = 105.26(3), gamma 108.17(5)degrees, V = 354.1(2)Angstrom (3), Z = 1, C12H16CuN2O8, M-r = 379.81, D-c = 1.791 Mg/m(3), F(000) 197, mu (MoK alpha) = 1.589 mm(-1). The final R and wR are 0.068 and 0.170 for 1249 observed reflections with I greater than or equal to2 sigma (I). The central copper ion is in a distorted octahedron geometry completed by two nitrogen atoms from carboxylic ligand, two oxygen atoms from hydroxyl groups and two oxygen atoms from coordinated water molecules. The intermolecular hydrogen bonding leads to the formation of a three-dimensional supramolecular structure.

关键词： hydrothermal reaction copper complex intermolecular hydrogen bonding

An iterative algorithm for analysis of coupled structural-acoustic systems subject to random excitations

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Acta Mechanica Sinica 2012年第2期28卷 458-467页

作者： Guo-zhong zhao Gang Chen Zhan Kang State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of Technology116024 DalianChina

This paper analyzes the random response of structural-acoustic coupled systems. Most existing works on coupled structural-acoustic analysis are limited to systems under deterministic excitations due to high computational cost required by a random response analysis. To reduce the computational burden involved in the coupled random analysis, an iterative procedure based on the Pseudo excitation method has been developed. It is found that this algorithm has an overwhelming advantage in computing efficiency over traditional methods, as demonstrated by some numerical examples given in this paper.

关键词： Random excitation Coupled structural-acoustic systems Pseudo excitation method

Effects of afforestation on soil carbon and its fractions:a case study from the Loess Plateau,China

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Journal of Forestry Research 2018年第5期29卷 1291-1297页

作者： Yang Gao Peng Dang zhong zhao Key Laboratory of Environment and Ecology in Western China of Ministry of Education College of ForestryNorthwest A&F University

Afforestation has been implemented to reduce soil erosion and improve the environment of the Loess Plateau,*** it increased soil organic carbon（SOC）,the stability of the increase is ***,the variations of soil inorganic carbon（SIC） following afforestation needs to be *** planting Robinia pseudoacacia,Pinus tabuliformis,and Hippophae rhamnoides on bare land on the Loess Plateau,total soil carbon（TSC） was measured and its two components,SIC and SOC,as well as the light and heavy fractions within SOC under bare lands and woodlands at the soil surface（0–20 cm）.The results show that TSC on bare land was 24.5 Mg ha^（-1） and significantly increased to 51.6 Mg ha^（-1） for ***,47.0 Mg ha^（-1） for *** and 39.9 Mg ha^（-1） for *** accumulated total soil carbon under ***,***,and ***,the heavy fraction（HFSOC） accounted for 65.2,31.7 and 76.2%,respectively; the light fraction（LF-SOC） accounted for 18.0,52.0 and 4.0%,respectively; SIC occupied 15.6,15.3 and 19.7%,*** accumulation rates of TSC under ***,***,and *** reached159.5,112.4 and 102.5 g m^（-2） a^（-1）,*** results demonstrate that afforestation on bare land has high potential for soil carbon accumulation on the Loess *** the newly sequestrated total soil carbon,the heavy fraction（HF-SOC） with a slow turnover rate accounted for a considerably high percentage,suggesting that significant sequestrated carbon can be stored in soils following ***,afforestation induces SIC *** its contribution to TSC accumulation was less than SOC,overlooking it may substantially underestimate the capacity of carbon sequestration after afforestation on the Loess Plateau.

关键词： Soil carbon sequestration Soil organic carbon Organic carbon fractions Soil inorganic carbon Afforestation

Heat stress-induced decapping of WUSCHEL mRNA enhances stem cell thermotolerance in Arabidopsis

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Molecular Plant 2024年第12期17卷 1820-1832页

作者： Sumei Liu Haijun Wu zhong zhao MOE Key Laboratory for Cellular Dynamics Hefei National Research Center for Physical Sciences at the MicroscaleThe First Affiliated Hospital of University of Science and Technology of ChinaSchool of Life SciencesDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230027China Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations Gansu Province Key Laboratory of Gene Editing for BreedingSchool of Life SciencesLanzhou UniversityLanzhou 730000China

The plasticity of stem cells in response to environmental change is critical for multicellular ***,we show that MYB3R-like directly activates the key plant stem-cell regulator WUSCHEL(WUS)by recruiting the methyltransferase ROOT INITIATION DEFECTIVE 2(RID2),which functions in m7G methylation of the 5′cap of WUS mRNA to protect it from *** and molecular analyses showed that protein-folding genes are repressed by WUS to maintain precise protein synthesis in stem cells by preventing the reuse of misfolded ***,we found that upon heat stress,the MYB3R-like/RID2 module is repressed to reduce WUS transcript abundance through decapping of nascent WUS *** releases the inhibition of protein-folding capacity in stem cells and protects them from heat shock by eliminating misfolded protein *** together,our results reveal a strategic trade-off whereby plants reduce the accuracy of protein synthesis in exchange for the survival of stem cells at high temperatures.

关键词： WUSCHEL decapping MYB3R-like methyltransferase thermotolerance

A 3D hybrid grid generation technique and a multigrid/parallel algorithm based on anisotropic agglomeration approach

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Chinese Journal of Aeronautics 2013年第1期26卷 47-62页

作者： Zhang Laiping zhao zhong Chang Xinghua He Xin State Key Laboratory of Aerodynamics China Aerodynamics Research and Development Center

A hybrid grid generation technique and a multigrid/parallel algorithm are presented in this paper for turbulence flow simulations over three-dimensional （3D） complex geometries. The hybrid grid generation technique is based on an agglomeration method of anisotropic tetrahedrons. Firstly, the complex computational domain is covered by pure tetrahedral grids, in which anisotropic tetrahedrons are adopted to discrete the boundary layer and isotropic tetrahedrons in the outer field. Then, the anisotropic tetrahedrons in the boundary layer are agglomerated to generate prismatic grids. The agglomeration method can improve the grid quality in boundary layer and reduce the grid quantity to enhance the numerical accuracy and efficiency. In order to accelerate the convergence history, a multigrid/parallel algorithm is developed also based on anisotropic agglomeration approach. The numerical results demonstrate the excellent accelerating capability of this multigrid method.

关键词： Anisotropic agglomeration approach Hybrid mesh generation Multigrid method Parallel computation Complex geometry

Dose reconstruction with Compton camera during proton therapy via subset-driven origin ensemble and double evolutionary algorithm

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Nuclear Science and Techniques 2023年第4期34卷 135-148页

作者： Zhi-Yang Yao Yong-Shun Xiao Ji-zhong zhao Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Particle&Radiation Imaging(Tsinghua University) Ministry of EducationBeijing 100084China

Compton camera-based prompt gamma(PG) imaging has been proposed for range verification during proton therapy. However, a deviation between the PG and dose distributions, as well as the difference between the reconstructed PG and exact values, limit the effectiveness of the approach in accurate range monitoring during clinical applications. The aim of the study was to realize a PG-based dose reconstruction with a Compton camera, thereby further improving the prediction accuracy of in vivo range verification and providing a novel method for beam monitoring during proton therapy. In this paper, we present an approach based on a subset-driven origin ensemble with resolution recovery and a double evolutionary algorithm to reconstruct the dose depth profile(DDP) from the gamma events obtained by a cadmium-zinc-telluride Compton camera with limited position and energy resolution. Simulations of proton pencil beams with clinical particle rate irradiating phantoms made of different materials and the CT-based thoracic phantom were used to evaluate the feasibility of the proposed method. The results show that for the monoenergetic proton pencil beam irradiating homogeneous-material box phantom,the accuracy of the reconstructed DDP was within 0.3 mm for range prediction and within 5.2% for dose prediction. In particular, for 1.6-Gy irradiation in the therapy simulation of thoracic tumors, the range deviation of the reconstructed spreadout Bragg peak was within 0.8 mm, and the relative dose deviation in the peak area was less than 7% compared to the exact values. The results demonstrate the potential and feasibility of the proposed method in future Compton-based accurate dose reconstruction and range verification during proton therapy.

关键词： Prompt gamma imaging Dose reconstruction Range verification Origin ensemble Compton camera Evolutionary algorithm

Effect of arginine on stability of GST-ZNF191(243-368)

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Chinese Chemical Letters 2007年第3期18卷 355-356页

作者： Dong Xin zhao zhong Xian Huang Chemical Biology Lab Department of Chemistry Fudan University Shanghai 200433 China

For better understanding the chemical or biological information of ZNF191 （243-368）, we expressed the fusion protein of GST and ZNF191 （243-368）, and used it to obtain the binding DNA sequence of this zinc finger protein. But in the process of expression and purification, we found this fusion protein slowly degradated. For resolving this problem, we simultaneously added charged amino acids L-Arg and L-Glu to the solution of fusion protein, and demonstrated that this method can dramatically increase the stability of this fusion protein. This method can make the fusion protein suitable for the continuous works, especially for situations where high protein concentration and long-term stability without precipitate and degradation of protein are required.

关键词： ZNF191(243-368) GST Stability L-Arg L-Glu

STREAMLINE-EQUIVORTICITY-LINE ITERATION METHOD FOR CALCULATING STEADY FLOW OF NONUNIFORM STREAM PAST A CIRCULAR CYLINDER

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Journal of Hydrodynamics 1991年第2期3卷 1-4页

作者： Zhai, Da-xi zhao, Han-zhong Huazhong Univ of Science and Technology Wuhan China

In this paper, an iteration method is presented to calculate the steady noseparation flow past a circular cylinder with brokenline-shaped velocity profile. At each iteration step, the streamlines of the last step are considered as equivorticity lines to determine the new flow field. The iterative process is stopped when certain convergence criterion is reached. Several examples are given which show the effectiveness of the method.

关键词： Fluid Mechanics Hydrodynamics Mathematical Techniques Piecewise Linear Techniques Stream Flow