检索结果-南通市图书馆

Acta Pharmaceutica Sinica B 2024年第4期14卷 1677-1692页

作者： Dongsheng Bai Jiawei zhao Runde Wang Jiaying Du Chen Zhou Chunyang Gu Yuxiang Wang Lulu Zhang yue zhao Na Lu State Key Laboratory of Natural Medicines Jiangsu Key Laboratory of Carcinogenesis and InterventionDepartment of PhysiologySchool of Basic Medicine and Clinical PharmacyChina Pharmaceutical UniversityNanjing 210009China Department of Clinical Pharmacology School of PharmacyNanjing Medical UniversityNanjing 211166China

Chemotherapy-induced mucositis represents a severe adverse outcome of cancer treatment,significantly curtailing the efficacy of these treatments and,in some cases,resulting in fatal *** identifying intestinal epithelial cell damage as a key factor in chemotherapy-induced mucositis,the paucity of effective treatments for such damage is *** our study,we discovered that Eubacterium coprostanoligenes promotes mucin secretion by goblet cells,thereby fortifying the integrity of the intestinal mucus *** enhanced barrier function serves to resist microbial invasion and sub-sequently reduces the inflammatory ***,this effect remains unobtrusive to the anti-tumor efficacy of chemotherapy ***,*** up-regulates the expression of AUF1,leading to the stabilization of Muc2 mRNA and an increase in mucin synthesis in goblet *** espe-cially significant finding is that *** activates the AhR pathway,thereby promoting the expression of *** summary,our results strongly indicate that *** enhances the intestinal mucus barrier,effec-tively alleviating chemotherapy-induced intestinal mucositis by activating the AhR/AUFl pathway,consequently enhancing Muc2 mRNA stability.

关键词： Chemotherapy Mucositis Eubacterium coprostanoligenes MUC2 AUF1

Identification of carbonates with high positive carbon isotope excursion from the Liaohe Group in the northeastern North China Craton and implications for the Lomagundi-Jatuli Event

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第9期67卷 2824-2844页

作者： Hongyu WANG Shuanhong ZHANG Sen WANG Linghao KONG yue zhao Qiqi ZHANG Sen GAO Guohui HU Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China Key Laboratory of Paleomagnetism and Tectonic Reconstruction Ministry of Natural ResourcesBeijing 100081China SinoProbe Laboratory Chinese Academy of Geological SciencesBeijing 100037China School of Earth Science and Mineral Resources China University of GeosciencesBeijing 100083China

The Great Oxidation Event(GOE)during the early Paleoproterozoic represents the first significant buildup in Earth’s atmospheric oxygen and resulted in a series of significant changes in the Earth’s surface *** them is the 2.22(or 2.33)–2.06 Ga Lomagundi-Jatuli Event(LJE),which is globally,the largest magnitude and longest duration,marine carbonate positive carbon isotope excursion(δ^(13)C_(V-PDB)>10‰)*** event has attracted the attention of scholars all over the ***,except for a high positive carbon isotope excursion(δ^(13)C_(V-PDB)>10‰)recently identified from marine carbonate rocks within the Daposhan Formation in the lower Fanhe Group(or the Sanchazi Group)in the Longgang Block in the northeast North China Craton(NCC),Paleoproterozoic carbonates in the NCC are characterized by a low-amplitude positive carbon isotope excursion(δ^(13)C_(V-PDB)10‰)of marine carbonate rocks occurred at about 2.15 *** co

关键词： Lomagundi-Jatuli Event(LJE) Great Oxidation Event(GOE) Carbon-oxygen isotopes Liaohe Group Marine carbonate Jiao-Liao-Ji Belt North China Craton

Assessment on gas-polyethylene terephthalate solid interface partial discharge properties of C4F7N/CO_(2)gas mixture for eco-friendly gas insulating transformer

在线全文

学校读者我要写书评

暂无评论

High Voltage 2024年第1期9卷 35-45页

作者： Song Xiao Yifan Wang Chenhua Ren Haoran Xia yue zhao Jingzi Qin Xiaoxing Zhang Yi Luo Yi Li State Key Laboratory of Power Grid Environmental Protection School of Electrical Engineering and AutomationWuhan UniversityWuhanHubeiChina Beijing International S&T Cooperation Base for Plasma Science and Energy Conversion Institute of Electrical EngineeringChinese Academy of SciencesBeijingChina State Grid Anhui Electric Power Company Anhui Electric Power Research Institute HefeiAnhuiChina Hubei Engineering Research Center for Safety Monitoring of New Energy and Power Grid Equipment School of Electrical and Electronic EngineeringHubei University of TechnologyWuhanHubeiChina

The eco-friendly insulating gas perfluoroisobutyronitrile(C_(4)F_(7)N)is potentially used in gas-insulated transformers(GIT)to replace sulphur hexafluoride(SF_(6)).However,evaluation of the long-term insulation reliability and gas–solid interface discharge decomposition characteristics of the gas–solid film insulation structure in GIT is *** authors simulated the gas–solid film insulation structure in GIT and explored the interface partial discharge(PD)characteristics of C4F7N/CO_(2)gas mixture with polyethylene terephthalate(PET).The effect of gas pressure,mixing ratio on gas–solid interface gas decomposition,PET degradation was investigated,and the interaction mechanism was *** is found that the interface PD generated three degradation regions on a PET *** gas–solid interface reaction in the electrode contact region and the discharge development trace was significantly higher than that of halation *** content of gas decomposition products decreases with the increase of gas pressure and the PD intensity of SF6-PET is inferior to that of C_(4)F_(7)N/CO_(2)under the same *** results provide reference for the development and application of C_(4)F_(7)N/CO_(2)based GIT.

关键词： interface solid insulation

A state-of-the-art review on delayed expansion of cemented paste backfill materials

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第8期43卷 3475-3500页

作者： Meng-Yuan Li Li-Jie Guo yue zhao Lei Zhang Kai Yang Xiao-Peng Peng Andrew Pan BGRIMM Technology Group Beijing 100160China National Centre for International Research On Green Metal Mining Beijing102628China Department of Civil and Mineral Engineering University of TorontoTorontoON M5S 1A4Canada

Utilizing delayed expansion cemented paste backfill materials(DECPB) in mine backfill operations offers an effective solution to the challenge of achieving proper contact between the in-situ cemented backfill mass and the roof in mined-out areas(backfill-roof contact).This article presents recent progress in both theoretical and experimental research concerning *** types and mechanisms of expansive additives,including expansive agents,foaming agents,and expansive mineral materials relevant to DECPB,are explained,along with their impact on the expansive properties and mechanical characteristics of *** composition,material characteristics,preparation methods,and controlled release mechanisms of microcapsules are *** methods for measuring the volume change rate of paste backfill slurries are *** indicates that an appropriate content of expansive additives not only enhances the expansive properties of cemented paste backfill materials but also contributes to improving their mechanical *** foaming agents and bentonite are found to be more suitable for preparing DECPB compared to expansive *** delayed expansion of cemented paste backfill material is influenced by microcapsules,with their wall materials,preparation parameters,and the alkaline slurry environment affecting their controlled release *** and optimizing precise measurement devices and methods forfor the volume change rate of cemented paste backfill materials is essential requirement for studying the performance of *** delayed expansion technology with retarding techniques in cemented paste backfill materials can provide a reliable solution for achieving proper backfill-roof contact in the future.

关键词： Paste backfill Delayed expansion Mining with backfill Expansive additives Tailings

Magnetic Bistability in the Crystaline Fullerene Radical Salt

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第17期42卷 2043-2048页

作者： Huapeng Ruan Ke Li Quanchun Sun Min Liu Zhongtao Feng Xue Dong yue zhao Xinping Wang State Key Laboratory of Coordination Chemistry School of Chemistry and Chemical EngineeringCollaborative Innovation Center of AdvancedMicrostructuresNanjing UniversityNanjingJiangsu210023China Department College of Materials and Chemical Engineering Pingxiang UniversityPingxiangJiangxi 337055China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of ScienceShanghai 200032China

Compounds with magnetic bistability is highly attractive for the construction of switches,thermal sensors,information-storage media and memory ***,we report a crystalline fullerene radical anion salt[Na(THF)_(5)]C_(60)(1),obtained by the reduction of C_(60) with Na in solution,which exhibits magnetic bistability accompanied with one magnetostructural transition,giving low temperature(LT),high temperature(HT)phases and a metastable phase.

关键词： Magnetic bistability Fullerene radical Structural transition Crystal structure Chain distortion Fullerene Magnetic materials π-πstacking

Copper-catalyzed conjugate addition of allene-derived nucleophiles to alkenyl-substituted carboxamides

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第3期35卷 239-242页

作者： Bin Fu yue zhao Xiuping Yuan Yanfei Li Jianjun Yin Simin Wang Tao Xiong Qian Zhang Jilin Province Key Laboratory of Organic Functional Molecular Design&Synthesis Department of ChemistryNortheast Normal UniversityChangchun 130024China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China School of Chemistry and Environmental Engineering Changchun University of Science and TechnologyChangchun 130012China

Catalytic Michael addition reaction represents a fundamental importance in organic synthetic *** corresponding conversions toward intrinsically low reactive enamide remains an ongoing *** herein report a copper-catalyzed conjugate addition of allenes toβ-substituted alkenyl amides,one of the most challenging Michael *** present method utilizes readily available allenes as the latent carbon-based nucleophiles and simple,commonβ-substituted alkenyl amides as starting materials,unlike previous methods that usually preinstall an activating group to improve the reactivity of amide or uses highly reactive stoichiometric quantities of ***,this approach shows good functional group compatibility and can be implemented under mild reaction conditions with excellent level of chemo-and regioselectivities.

关键词： CuH catalysis Allenes Unsaturated amide Conjugate addition Regioselectivity

Dynamically switchable porphyrin-based molecular tweezer for on-off fullerene recognition

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第6期35卷 283-287页

作者： Zhimin Sun Xin-Hui Guo yue zhao Qing-Yu Meng Li-Juan Xing He-Lue Sun College of Chemistry and Materials Science Hebei Key Laboratory of Organic Functional MoleculesHebei Normal UniversityShijiazhuang 050024China

Herein,a novel molecular tweezer based on 2,2'-bipyridine-bridged porphyrin subunits was constructed for efficient fullerenes *** syn conformation of the molecule,which was obtained by Zn(Ⅱ)coordination,gives rise to a proper cavity to interact with fullerene guests to form a stable 1:1 complex in toluene *** exhibits distinct binding selectivity towards C_(60)over C_(70).Moreover,the fullerene recognition capacity can be adequately suppressed by importing H_(2)PO_(4)^(-)to competitively capture Zn(Ⅱ)along with syn-anti conformational ***,the molecular tweezer regenerated to bind the fullerene by introducing the Ca^(2+)into the ***,the association-disassociation process can be switched reversibly and repeatedly.

关键词： Molecular tweezer Fullerene recognition Supramolecular chemistry Conformation conversion Coordination

China-Vietnam Railway Positive Signals

在线全文

学校读者我要写书评

暂无评论

China Weekly 2024年第7期 14-17页

作者： zhao yue 不详

As China's high-speed railway technologies earn a reputation in Southeast Asia,Vietnam is set to strengthen its cooperation with China's Belt and Road Initiative on cross-border railway projects.

关键词： Vietnam railway Southeast

High-visibility ghost imaging with phase-controlled discrete classical light sources

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2024年第7期33卷 328-334页

作者：仵雪滢赵岳李利明 School of Physics and Optoelectronic Engineering Shandong University of TechnologyZibo 255049China

We take phase modulation to create discrete phase-controlled sources and realize the super-bunching effect by a phasecorrelated method. From theoretical and numerical simulations, we find the space translation invariance of the bunching effect is a key point for the ghost imaging realization. Experimentally, we create the orderly phase-correlated discrete sources which can realize high-visibility second-order ghost imaging than the result with chaotic sources. Moreover, some factors affecting the visibility of ghost image are discussed in detail.

关键词： ghost imaging high visibility space translation invariance

北京2022年冬奥会六足冰壶机器人机构设计与运动规划

在线全文

学校读者我要写书评

暂无评论

Engineering 2024年第4期35卷 15-31页

作者： Ke Yin yue Gao Feng Gao Xianbao Chen yue zhao Yuguang Xiao Qiao Sun Jing Sun School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of Mechanical System and Vibration School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China

When a curling rock slides on an ice sheet with an initial rotation,a lateral movement occurs,which is known as the curling *** force of friction between the curling rock and the ice sheet changes continually with changes in the environment;thus,the sport of curling requires great skill and *** throwing of the curling rock is a great challenge in robot design and control,and existing curling robots usually adopt a combination scheme of a wheel chassis and gripper that differs significantly from human throwing movements.A hexapod curling robot that imitates human kicking,sliding,pushing,and curling rock rotating was designed and manufactured by our group,and completed a perfect show during the Beijing 2022 Winter Olympics *** switching between the walking and throwing tasks is realized by the robot’s morphology transformation based on leg configuration *** robot’s controlling parameters,which include the kicking velocity v_(k),pushing velocity v_(p),orientation angle θc,and rotation velocityω,are determined by aiming and sliding models according to the estimated equivalent friction coefficientμ_(equ)and ratio e of the front and back *** stable errors between the target and actual stopping points converge to 0.2 and 1.105 m in the simulations and experiments,respectively,and the error shown in the experiments is close to that of a well-trained wheelchair curling *** robot holds promise for helping ice-makers rectify ice sheet friction or assisting in athlete training.

关键词： Legged robot Curling robot Winter Olympics Mechanism design Motion planning