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Eight-sided fortress: a lightweight block cipher

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The Journal of China Universities of Posts and Telecommunications 2014年第1期21卷 104-108,128页

作者： LIU Xuan zhang wen-ying LIU Xiang-zhong LIU Feng School of Information Science and Engineering Shandong Normal University Science and Technology on Information Assume Laboratory State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of Sciences No.2 Middle School Attached to Shandong Normal University

In this paper, we present a new lightweight block cipher named eight-sided fortress（ESF）, which is suitable for resource-constrained environments such as sensor networks and low-cost radio rrequency identification（RFID） tags. Meanwhile, we present the specification, design rationale and evaluation results in terms of the hardware implementation. For realizing both efficiency and security in embedded systems, similar to the other lightweight block ciphers, ESF is 64 bits block length and key size is 80 bits. It is inspired from existing block cipher, PRESENT and LBlock. The encryption algorithm of ESF is based on variant Feistel structure with SPN round function, used Feistel network as an overall structure with the purpose of minimizing computational resources.

关键词： block cipher lightweight RFID tags efficiency cryptography design

Down-regulation of PTEN expression due to loss of promoter activity in human hepatocellular carcinoma cell lines

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World Journal of Gastroenterology 2005年第29期11卷 4472-4477页

作者： Dong-Zhu Ma Zhen Xu Yu-Long Liang Jian-Ming Su Zeng-Xia Li wen zhang Li-ying Wang Xi-Liang Zha Ministry of Health Key Laboratory of Glycocojugate Research Department of Biochemistry and Molecular Biology Shanghai Medical College Fudan University Shanghai 200032 China

AIM: To investigate the regulation of phosphatase and tensin homolog deleted on chromosome ten (PTEN) gene expression in human hepatocellular carcinoma (HCC) cell ***: The mRNA and protein levels of PTEN were detected by Northern blot and Western blot in HCC cell lines, respectively. Plasmids containing different fragments of PTEN promoter with Luciferase reporter were constructed and transiently transfected into HCC cell lines to study the promoter activity. DNA analysis and RT-PCR were performed to detect the mutation of PTEN promoter and PTEN ***: Either protein or mRNA levels of PTEN in L02 cells (as a control) were significantly higher than that in HCC cell lines. The profile of PTEN promoter activity in 8 cell lines was closely correlated with levels of PTEN mRNA and PTEN protein. Furthermore, the sequence analysis of 8 cells lines showed no mutation in the region of PTEN promoter and ***: PTEN expression is down-regulated in HCC cell lines probably due to loss of activity of PTEN promoter.

关键词： Phosphatase Tensin homolog Hepatocellular carcinoma

Structure and Infrared Radiation Property of Co_(1-x)ZnxFe_2O_4 Ferrites by XAFS Analysis

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Journal of Wuhan University of Technology(Materials Science) 2009年第6期24卷 907-911页

作者：张英 Inorganic Materials Department College of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou China

Co1-xZnxFe2O4 ferrites were prepared by solid state reaction. The microstructure and performance were studied by X-ray diffraction, X-ray absorption fine-structure analysis and IRE-2 infrared radiant test. It is found that infrared radiance show a nonlinear change with x, exhibiting the infrared radiance of this material improved and the average radiance in the 8-14 μm waveband reached 0.91. The Co^3＋ and Zn^2＋ ions are found to occupy both tetrahedral and octahedral sites, and correspondingly, the fraction of Fe^3＋ ions in B-site decreases nonlinearly in ferrites. The lattice parameters are found to concern with Zn^2＋, and the activation energy deduces from crystal strain and crystal vibrate increases with content Zn^2＋. The redistribution of the Co^3＋ and Zn^2＋ ions between tetrahedral and octahedral sites is related to the providing a selective tetrahedral and octahedral sites infrared radiance of Co1-xZnxFe2O4 ceramics with increasing x.

关键词： ferrites XAFS crystal structure infrared radiation property

Prevalence of high-risk human papillomavirus infection in different cervical lesion among organized health-examination women in Shanghai, China

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Chinese Medical Journal 2008年第16期121卷 1578-1582页

作者： zhang wen-ying XUE Yue-zhen CHEN Min HAN Ling LUO Man Department of Obstetrics and Gynecology Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China Department of Gynecology Obstetrics and Gynecology Hospital Fudan University Shanghai 200011 China

Background Cervical cancer is the second most common cause of death from cancer among women worldwide. Human papillomavirus （HPV） plays a central role in the etiology of cervical cancer. It is important to describe the prevalence of HPV infection in different types of cervical lesions and to explore the relation between HPV viral load and the severity of cervical lesions. Methods To describe the HPV infection prevalence and viral load in different age groups, we retrospectively investigated 6405 cases of women who were organized by their units to take health-examination. They were given Hybrid Capture II tests between January 2005 and December 2006. The correlation between HPV viral load and pathology was assessed. Results Overall HPV infection prevalence was 29.1% （1864/6405）, while in women 18-20 years old it was 54.4% （31/57）, the highest among all age groups. After declining rapidly, HPV prevalence stabilized at about 30.0% in women aged 30 and older. Of the 6405 women, 1483 women had a colposcopic biopsy and 33.2% （492/1483） were positive for HPV DNA. Twenty-one percent of women with a normal diagnosis （238/1095） had HPV infection, a statistically significantly lower prevalence than in women with cervical lesions, including those with cervical intraepithelial neoplasia （68.8% in CIN1,66.7% in CIN2, and 76.5% in CIN3） or with cervical cancer （94.1%）. The correlation coefficient between viral load and cervical lesion severity was 0.134, which was not statistically significant （P=0.075）. Viral load values in women with CINs and cervical cancer were calculated, and no significant differences were identified. Conclusions The prevalence of high-risk HPV infection among women attending hospitals for health-examination in Shanghai is similar to the worldwide rate. HPV viral load can distinguish cervical lesions from normal individuals but cannot adequately predict the severity of cervical lesions.

关键词： human papillomavirus prevalence viral load, cervical intraepithelial neoplasia uterine cervical neoplasms

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带有偏序锥的DEARA模型研究及应用

控制与决策 2018年第7期33卷 1171-1180页

作者：张炳江张文英北京信息科技大学理学院北京100192

数据包络分析(DEA)和回归分析(RA)两种方法都是处理多属性决策问题中常用的方法,前者的评价基准是基于"优秀者",后者的评价基准是基于"平均像".将这两种方法结合起来形成一个统一的评价方法,即DEARA方法,可以实现从"优秀者"到"平均像"... 详细信息

数据包络分析(DEA)和回归分析(RA)两种方法都是处理多属性决策问题中常用的方法,前者的评价基准是基于"优秀者",后者的评价基准是基于"平均像".将这两种方法结合起来形成一个统一的评价方法,即DEARA方法,可以实现从"优秀者"到"平均像"的连续评价.此外,一种锥比率DEA模型C^2WH可以利用锥比率体现决策者对样本指标和决策单元的偏好,基于此模型,提出一种带有偏序锥的DEARA模型.最后,将所提出模型应用于我国铁路运输企业的效率分析上,通过实例表明所提出的模型在处理客观数据与主观因素并存的多属性决策中的合理性.

关键词：多目标多属性决策数据包络分析回归分析约束锥绩效评价

A Comparison between Volume Responsiveness Predicted by Changes in Pulse Pressure and by Changes in Stroke Volume Induced by Passive Leg Raising

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麻醉与监护论坛 2011年第2期18卷 114-118,121页

作者： Lei Huang Wei-xing zhang wen-xun Cai ying-qun Cheng ying-xin Lin Department of Intensive Care Unit Peking University Shenzhen Hospital Shenzhen Guangdong 518036 China

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数据仓库技术在昆明电网电量分析中的应用

电网技术 2005年第14期29卷 40-44页

作者：张文英束洪春张叶昆明理工大学电力工程学院云南省昆明市650093 昆明供电局云南省昆明市650011

数据仓库技术对操作型数据转化成全面、集成的信息,以及对海量数据的查询和统计提供了有效的途径。文章在介绍数据仓库、联机分析处理概念和技术的基础上,分析了面向主题的多维数据库的建立和多维视图的展现等技术,针对昆明电网负荷管... 详细信息

数据仓库技术对操作型数据转化成全面、集成的信息,以及对海量数据的查询和统计提供了有效的途径。文章在介绍数据仓库、联机分析处理概念和技术的基础上,分析了面向主题的多维数据库的建立和多维视图的展现等技术,针对昆明电网负荷管理系统,基于微软的SQLServer2000和SQLAnalysisServices2000构建了面向电量主题的数据仓库,在数据可视化方面弥补了AnalysisServices2000的不足。同时讨论了数据仓库技术在完成电量数据的查询、统计、分析、生成各种统计报表方面的具体应用。

关键词：数据仓库电量管理联机分析多维视图数据挖掘电力系统

基于PI3K/Akt信号通路探讨乌梅丸含药血清对胰腺癌细胞增殖、侵袭、迁移和凋亡的影响

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中国实验方剂学杂志 2022年第6期28卷 34-42页

作者：王熙张莹雯湖北中医药大学武汉430061 武汉市中医医院武汉430014 武汉大学中南医院武汉430071

目的:观察乌梅丸含药血清对人胰腺癌SW1990细胞增殖、侵袭、迁移和凋亡的影响,同时探讨其可能的作用机制。方法:制备乌梅丸含药血清,体外培养胰腺癌细胞株SW1990,采用细胞增殖与活性检测(CCK-8)法筛选乌梅丸含药血清最佳作用时间用于后... 详细信息

目的:观察乌梅丸含药血清对人胰腺癌SW1990细胞增殖、侵袭、迁移和凋亡的影响,同时探讨其可能的作用机制。方法:制备乌梅丸含药血清,体外培养胰腺癌细胞株SW1990,采用细胞增殖与活性检测(CCK-8)法筛选乌梅丸含药血清最佳作用时间用于后续实验;将SW1990细胞分为空白组和乌梅丸低、中、高组(含药血清2%、4%、8%),利用平板克隆实验、细胞划痕实验和细胞侵袭实验分别检测其克隆形成、迁移和侵袭能力;流式细胞术检测乌梅丸含药血清对胰腺癌SW1900细胞凋亡的影响;通过蛋白免疫印迹法(Western blot)检测SW1990细胞中凋亡相关蛋白,B细胞淋巴瘤-2(Bcl-2),Bcl-2相关X蛋白(Bax),细胞色素C(Cyt C),活化的半胱氨酸天冬氨酸蛋白水解酶-3(cleaved Caspase-3)、cleaved Caspase-9,磷脂酰肌醇3-激酶/蛋白激酶B(PI3K/Akt)通路中PI3K,磷酸化(p)-PI3K,Akt,磷酸化(p)-Akt蛋白表达水平。结果:与空白组比较,作用72 h,乌梅丸低、中、高组吸光度A显著降低(P<0.01),与乌梅丸低组比较,乌梅丸中、高组A均显著降低(P<0.01),与乌梅丸中组比较,乌梅丸高组A显著降低(P<0.01),说明乌梅丸作用72 h可呈剂量依赖性抑制SW1990细胞增殖能力,药物最佳作用时间为72 h;与空白组比较,乌梅丸低、中、高组SW1990细胞侵袭能力显著减弱(P<0.01),且呈浓度依赖性;与空白组比较,乌梅丸低、中、高组细胞克隆形成能力、迁移能力均有下降(P<0.05,P<0.01),且呈浓度依赖性;与空白组比较,乌梅丸低、中、高组细胞的总凋亡率显著升高(P<0.01),乌梅丸诱导凋亡作用随给药剂量增加而增强;与空白组比较,乌梅丸低、中、高组Bcl-2蛋白表达显著降低(P<0.01),cleaved Caspase-3,cleaved Caspase-9,Cyt C,Bax蛋白表达升高(P<0.05,P<0.01),且呈现出一定的量效关系;与空白组比较,乌梅丸低、中、高组p-PI3K,p-Akt蛋白表达均有减少(P<0.05,P<0.01),且随着剂量的增加,蛋白表达逐渐降低,p-PI3K/PI3K,p-Akt/Akt明显降低(P<0.05,P<0.01),且随着剂量的增加,比值逐渐降低。结论:乌梅丸能明显抑制胰腺癌SW1990细胞的恶性生物学行为,诱导细胞凋亡,其机制可能与抑制PI3K/Akt信号通路,下调PI3K/Akt通路中的蛋白磷酸化水平有关。

关键词：乌梅丸含药血清胰腺癌增殖侵袭转移磷脂酰肌醇3-激酶/蛋白激酶B(PI3K/Akt)信号通路

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控制系统故障检测与诊断技术的最新进展

系统工程与电子技术 2007年第4期29卷 659-664页

作者：张爱玲张文英张端金郑州大学信息工程学院河南郑州450052

对故障检测与诊断(FDD)技术在控制领域的最新进展进行了综述,内容主要包括三类基本方法,即:基于解析模型的FDD、基于信号处理和基于知识的故障检测与诊断方法。重点评述了近年来发展起来的信息融合方法、多Agent方法、鲁棒故障检测、网... 详细信息

对故障检测与诊断(FDD)技术在控制领域的最新进展进行了综述,内容主要包括三类基本方法,即:基于解析模型的FDD、基于信号处理和基于知识的故障检测与诊断方法。重点评述了近年来发展起来的信息融合方法、多Agent方法、鲁棒故障检测、网络控制系统的故障诊断等。最后介绍了故障检测与诊断技术在控制系统中的若干应用成果,并指出尚待解决的主要问题和值得进一步研究的方向。

关键词：控制系统故障检测与诊断解析模型鲁棒性