检索结果-南通市图书馆

International Journal of Ophthalmology(English edition) 2024年第4期17卷 761-766页

作者： Su-Lan Wu Yi-Qi Chen Li-Jun Shen jian-Bo Mao Li Lin Ji-Wei Tao huan Chen Shi-An zhang jia-Feng yu Chen-Xi Wang Center for Rehabilitation Medicine Department of OphthalmologyZhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina The Affiliated Eye Hospital of Wenzhou Medical University in Hangzhou Hangzhou 310000Zhejiang ProvinceChina

AIM:To evaluate scleral buckling(SB)surgery using a noncontact wide-field viewing system and 23-gauge intraocular illumination for the treatment of rhegmatogenous retinal detachment in silicone oil(SO)-filled ***:Totally 9 patients(9 eyes)with retinal detachment in SO-filled eyes were retrospectively *** patients underwent non-contact wide-field viewing system-assisted buckling surgery with 23-gauge intraocular *** was removed at an appropriate time based on *** patients were followed up for at least 3mo after SO *** reattachment,complications,visual acuity and intraocular pressure(IOP)before and after surgery were ***:Patients were followed up for a mean of 8.22mo(3-22mo)after SO *** patients had retinal *** the final follow-up,visual acuity showed improvement for 8 patients,and no change for 1 *** IOP was high in 3 patients before surgery,but it stabilized after treatment;it was not affected in the other *** of the patients had infections,hemorrhage,anterior ischemia,or any other ***:This new non-contact wide-field viewing system-assisted SB surgery with 23-gauge intraocular illumination is effective and safe for retinal detachment in SO-filled eyes.

关键词： non-contact wide-field viewing system scleral buckling silicone oil-filled retinal detachment

Tumour response following preoperative chemotherapy is affected by body mass index in patients with colorectal liver metastases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第2期16卷 331-342页

作者： hua-Chuan Song Hang-Cheng Zhou Ping Gu Bing Bao Quan Sun Tian-Ming Mei Wei Cui Kang Yao huan-zhang Yao Shen-yu zhang Yong-Shuai Wang Rui-Peng Song Ji-Zhou Wang Department of General Surgery Provincial Hospital Affiliated to Anhui Medical UniversityHefei 230001Anhui ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Pathology The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Gastrointestinal Surgery Tongcheng People’s HospitalTongcheng 231400Anhui ProvinceChina Department of Gastrointestinal Surgery Suzhou Hospital Affiliated to Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina Department of General Surgery Xuancheng People’s HospitalXuancheng 242000Anhui ProvinceChina

BACKGROUND Colorectal cancer is the third most prevalent malignancy globally and ranks second in cancer-related mortality,with the liver being the primary organ of *** chemotherapy is widely recommended for initially or potentially resectable colorectal liver metastases(CRLMs).Tumour pathological response serves as the most important and intuitive indicator for assessing the efficacy of ***,the postoperative pathological results reveal that a considerable number of patients exhibit a poor response to preoperative *** mass index(BMI)is one of the factors affecting the tumori-genesis and progression of colorectal cancer as well as prognosis after various antitumour *** studies have indicated that overweight and obese patients with metastatic colorectal cancer experience worse prognoses than those with normal weight,particularly when receiving first-line chemotherapy regimens in combination with *** To explore the predictive value of BMI regarding the pathologic response following preoperative chemotherapy for *** A retrospective analysis was performed in 126 consecutive patients with CRLM who underwent hepatectomy following preoperative chemotherapy at four different hospitals from October 2019 to July *** and multivariate logistic regression models were applied to analyse potential predictors of tumour pathological *** Kaplan-Meier method with log rank test was used to compare progression-free survival(PFS)between patients with high and low ***<24.0 kg/m^(2) was defined as low BMI,and tumour regression grade 1-2 was defined as complete tumour *** Low BMI was observed in 74(58.7%)patients and complete tumour response was found in 27(21.4%)*** rate of complete tumour response was significantly higher in patients with low BMI(29.7%vs 9.6%,P=0.007).Multivariate analysis revealed that low BMI[odds ratio(OR)=4.56,95%confidence interval(CI):1

关键词： Colorectal liver metastases Body mass index Tumour regression grade Preoperative chemotherapy Hepatectomy

Catalytic Asymmetric Diastereodivergent Synthesis of 2-Alkenylindoles Bearing both Axial and Central Chirality

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Precision Chemistry 2024年第5期2卷 208-220页

作者： Shuang Yang jia-Bo huang Da-hua Wang Ning-Yi Wang yu-yu Chen Xin-Yan Ke Hao Chen Shao-Fei Ni yu-Chen zhang Feng Shi Research Center of Chiral Functional Heterocycles School of Chemistry and Materials ScienceJiangsu Normal UniversityXuzhou 221116China Department of Chemistry Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong ProvinceShantou UniversityShantou 515063China Department of Otolaryngology Xuzhou First People’s HospitalAffiliated Xuzhou Municipal Hospital of Xuzhou Medical UniversityXuzhou 221002China School of Petrochemical Engineering Changzhou UniversityChangzhou 213164China

The catalytic asymmetric diastereodivergent synthesis of axially chiral 2-alkenylindoles was established via chiral phosphoric acid-catalyzed addition reactions of C3-unsubstituted 2-alkenylindoles with o-hydroxybenzyl alcohols under different reaction *** this strategy,two series of 2-alkenylindoles bearing both axial and central chirality were synthesized in a diastereodivergent fashion with moderate to high yields and good stereoselectivities(up to 99%yield,95:5 er,>95:5 dr).Moreover,theoretical calculations were performed on the key transition states leading to different stereoisomers,which provided an in-depth understanding of the origin of the observed stereoselectivity and diastereodivergence of the products under different reaction *** importantly,these 2-alkenylindoles were utilized in asymmetric catalysis as chiral organocatalysts and in medicinal chemistry for evaluation of their cytotoxicity,which demonstrated their potential *** study has not only established the catalytic atroposelective synthesis of axially chiral 2-alkenylindoles,but also provided an efficient strategy for catalytic asymmetric diastereodivergent construction of indole-based scaffolds bearing both axial and central chirality.

关键词： 2-Alkenylindole Axial chirality Central chirality Diastereodivergent synthesis Chiral phosphoric acid

The effect of secondary phase on corrosion behaviors of the titanium–zirconium–molybdenum alloy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tungsten 2024年第2期6卷 342-354页

作者： Song-Wei Ge Ping Hu Jie Deng Shi-Lei Li Hai-Rui Xing jia-yu Han Xing-jiang hua Li Wang Jun-Zhou Yang Bo Jin Wen zhang Kuai-She Wang School of Metallurgy Engineering Xi’an University of Architecture and TechnologyXi’an 710055China National and Local Joint Engineering Research Center for Functional Materials Processing Xi’an University of Architecture and TechnologyXi’an 710055China Western Xinxing Rare and Precious Metals Co. Ltd.Shangluo 726000China Northwest Institute for Non-Ferrous Metal Research Xi’an 710016China

As the range of applications for molybdenum and its alloys has expanded,the corrosive environment for molybdenum alloys has become more *** the past,the content of doping elements has been studied to investigate their infl uence on the corrosion performance of titanium–zirconium–molybdenum(TZM)*** this paper,it is considered that the second phase in the alloy is the main factor aff ecting the corrosion performance of TZM *** comparing the corrosion behavior of molybdenum metal and TZM alloy,the eff ect of the secondary phase on corrosion behaviors of TZM alloy has been *** results show that the second phase reduces the corrosion resistance of the TZM *** potential of the second phase is 73.7 mV higher than that of the Mo matrix,which contributes to the formation of microscopic electric *** the action of microscopic electric couples,pitting corrosion is preferentially formed at the interface between the second phase and the matrix,which accelerates the corrosion of the *** paper provides a theoretical basis for the application of TZM alloys in corrosive environments.

关键词： Secondary phase Electrochemical corrosion Titanium–zirconium–molybdenum(TZM) Galvanic corrosion Corrosion resistance

Development of a High-throughput Sequencing Platform for Detection of Viral Encephalitis Pathogens Based on Amplicon Sequencing

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第3期37卷 294-302页

作者： zhang Ya Li SU Wen Zhe WANG Rui Chen LI Yan zhang Jun Feng LIU Sheng Hui HU Dan He XU Chong Xiao YIN jia yu YIN Qi Kai HE Ying LI Fan FU Shi Hong NIE Kai LIANG Guo Dong TAO Yong XU Song Tao MA Chao Feng WANG huan yu Shaanxi University of Chinese Medicine Xianyang 712000ShaanxiChina National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China Guangzhou Center for Disease Control and Prevention Guangzhou 510000GuangdongChina Shandong Center for Disease Control and Prevention Jinan 250000ShandongChina Department of Ophthalmology Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Xi'an Center for Disease Control and Prevention Xi’an 710054ShaanxiChina

Objective Viral encephalitis is an infectious disease severely affecting human *** is caused by a wide variety of viral pathogens,including herpes viruses,flaviviruses,enteroviruses,and other *** laboratory diagnosis of viral encephalitis is a worldwide ***,high-throughput sequencing technology has provided new tools for diagnosing central nervous system ***,In this study,we established a multipathogen detection platform for viral encephalitis based on amplicon *** We designed nine pairs of specific polymerase chain reaction(PCR)primers for the 12 viruses by reviewing the relevant *** detection ability of the primers was verified by software simulation and the detection of known positive *** sequencing was used to validate the samples,and consistency was compared with Sanger *** The results showed that the target sequences of various pathogens were obtained at a coverage depth level greater than 20×,and the sequence lengths were consistent with the sizes of the predicted *** sequences were verified using the National Center for Biotechnology Information BLAST,and all results were consistent with the results of Sanger *** Amplicon-based high-throughput sequencing technology is feasible as a supplementary method for the pathogenic detection of viral *** is also a useful tool for the high-volume screening of clinical samples.

关键词： Viral encephalitis Amplicon sequencing High-throughput sequencing Multipathogen detection

Genomic data and ecological niche modeling reveal an unusually slow rate of molecular evolution in the Cretaceous Eupteleaceae

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第4期67卷 803-816页

作者： Kun-Li Xiang Sheng-Dan Wu Lian Lian Wen-Chuang He Dan Peng huan-Wen Peng Xiao-Ni zhang Hong-Lei Li jia-yu Xue Hong-Yan Shan Gui-Xia Xu Yang Liu Zhi-Qiang Wu Wei Wang State Key Laboratory of Plant Diversity and Specialty Crops Institute of BotanyChinese Academy of SciencesBeijing 100093China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyLaboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China China National Botanical Garden Beijing 100093China State Key Laboratory of Grassland Agro-Ecosystems and College of Ecology Lanzhou UniversityLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China College of Landscape Architecture and Life Science/Institute of Special Plants Chongqing University of Arts and SciencesChongqing 402160China College of Horticulture Academy for Advanced Interdisciplinary StudiesNanjing Agricultural UniversityNanjing 210095China Fairylake Botanical Garden Shenzhen&Chinese Academy of SciencesShenzhen 518004China

Living fossils are evidence of long-term sustained ecological ***,whether living fossils have little molecular changes remains poorly known,particularly in ***,we have introduced a novel method that integrates phylogenomic,comparative genomic,and ecological niche modeling analyses to investigate the rate of molecular evolution of Eupteleaceae,a Cretaceous relict angiosperm family endemic to East *** assembled a high-quality chromosome-level nuclear genome,and the chloroplast and mitochondrial genomes of a member of Eupteleaceae(Euptelea pleiosperma).Our results show that Eupteleaceae is most basal in Ranunculales,the earliest-diverging order in eudicots,and shares an ancient whole-genome duplication event with the other *** document that Eupteleaceae has the slowest rate of molecular changes in the observed *** unusually low rate of molecular evolution of Eupteleaceae across all three independent inherited genomes and genes within each of the three genomes is in association with its conserved genome architecture,ancestral woody habit,and conserved niche *** findings reveal the evolution and adaptation of living fossil plants through large-scale environmental change and also provide new insights into early eudicot diversification.

关键词： conservation genomics eudicots evolutionary rates niche conservatism phylogenomics

2023:A year of accomplishments for the 13 Science Citation Index Expanded-and Emerging Sources Citation Index-indexed Baishideng journals

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第1期30卷 9-16页

作者： Jin-Lei Wang jia-Ping Yan jia-Ru Fan Xiang Li Xu Guo jia-Wei Li yun-Xiaojian Wu Jing-Jie Wang yu-Lu Chen Li Li Cong Lin Xin-Liang Qu Ji-Hong Liu Yan-Liang zhang Ying-Yi yuan hua-Ge yu yu-Xi Chen Yi-Xuan Cai Xiang-Di zhang Si Zhao Zi-Hang Xu Li Ma Na Ma Diao-Mei Guo Lian-Sheng Ma Baishideng Publishing Group Inc PleasantonCA 94566United States

In 2023,Baishideng Publishing Group(Baishideng)routinely published 47 openaccess journals,including 46 English-language journals and 1 Chinese-language *** successes were accomplished through the collective dedicated efforts of Baishideng staffs,Editorial Board Members,and Peer *** these 47 Baishideng journals,7 are included in the Science Citation Index Expanded(SCIE)and 6 in the Emerging Sources Citation Index(ESCI).With the support of Baishideng authors,company staffs,Editorial Board Members,and Peer Reviewers,the publication work of 2023 is about to be successfully *** editorial summarizes the 2023 activities and accomplishments of the 13 SCIEand ESCI-indexed Baishideng journals,outlines the Baishideng publishing policy changes and additions made this year,and highlights the unique advantages of Baishideng journals.

关键词： Baishideng Publishing Group Journal Impact Factor Open access Policy changes Policy additions Unique advantages Anxiety disorders Colorectal cancer Inflammatory bowel disease Hepatocellular carcinoma Gut microbes Atrial fibrillation

Current Mycoplasma pneumoniae epidemic among children in Shanghai:unusual pneumonia caused by usual pathogen

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第1期20卷 5-10页

作者： Xiao-Bo zhang Wen He Yong-Hao Gui Quan Lu Yong Yin jian-hua zhang Xiao-Yan Dong Ying-Wen Wang Ying-Zi Ye Hong Xu jia-yu Wang Bing Shen Dan-Ping Gu Li-Bo Wang Yi Wang Department of Respiratory Medicine Children's Hospital of Fudan University399 Wanyuan RoadShanghai 201102China State Key Laboratory of Genetic Engineering at School of Life Sciences Institute of Reproduction&DevelopmentChildren's Hospital of Fudan UniversityShanghaiChina Department of Respiratory Medicine Children's Hospital of Shanghai Jiao Tong UniversityShanghaiChina Department of Respiratory Medicine Shanghai Children's Medical CenterAffiliated to Shanghai Jiaotong University School of MedicineShanghaiChina Department of Pediatric Respiratory Xinhua HospitalAffiliated to Shanghai Jiaotong University School of MedicineShanghaiChina Department of Nursing Children's Hospital of Fudan UniversityShanghaiChina Department of Infectious Diseases Children's Hospital of Fudan UniversityShanghaiChina Department of Nephrology Children's Hospital of Fudan UniversityShanghaiChina NHC Key Laboratory of Neonatal Diseases Children's Hospital of Fudan UniversityShanghaiChina Shanghai Shenkang Hospital Development Center ShanghaiChina Center for Medical Quality Control Management of Shanghai ShanghaiChina Department of Neurology Children's Hospital of Fudan University399Wanyuan RoadShanghai 201102China

Mycoplasma pneumoniae(***),primarily transmitted through respiratory droplets when infected individuals cough or sneeze,is a common cause of communityacquired pneumonia,especially among school-age children and *** infection occurs endemically with an epidemic peak every few *** worldwide incidence confirmed by direct test methods was reported to be 8.61%between 2017 and 2020 across all age groups[1].

关键词： pneumonia epidemic respiratory

Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis:a nationwide retrospective study in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第5期20卷 506-516页

作者： Li-Wen Tan Jun-Li Wan Chun-hua Zhu Hong Xu Zheng-Kun Xia Li-Zhi Chen Xiao-Chuan Wu Fang Wang Xiao-Rong Liu Cheng-Guang Zhao Xiao-Zhong Li jian-hua Mao Xiao-Wen Wang Wen-Yan huang yu-Hong Li jian-jiang zhang Shi-Pin Feng Jun Yang jiao-jiao Liu Chun-Lin Gao Li-Ping Rong Lan-Jun Shuai Ke Xu He-jia zhang Qiu Li Ai-hua zhang Mo Wang Department of Nephrology Children’s Hospital of Chongqing Medical UniversityZhongshan 2nd Rd.136Chongqing400014China Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChildren’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Pediatrics Children’s Hospital of Chongqing Medical UniversityChongqingChina Department of Nephrology Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing210008China Department of Nephrology Children’s Hospital of Fudan UniversityNational Paediatric Medical Center of ChinaShanghaiChina Department of Pediatrics Jinling HospitalNanjing Medical UniversityNanjingChina Department of Pediatrics Jinling HospitalThe First School of Clinical MedicineSouthern Medical UniversityNanjingChina Department of Pediatrics Jinling HospitalMedical School of Nanjing UniversityNanjingChina Department of Pediatric Nephrology and Rheumatology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouChina Department of Pediatrics The Second Xiangya Hospital of Central South UniversityChangshaChina Department of Pediatrics Peking University First HospitalBeijingChina Department of Nephrology Beijing Children’s HospitalCapital Medical UniversityBeijing100045China National Center for Children’s Health BeijingChina Department of Pediatrics Shengjing Hospital of China Medical UniversityShenyangChina Department of Nephrology and Immunology Children’s Hospital of Soochow UniversitySuzhouChina Department of Nephrology Children HospitalZhejiang University School of MedicineHangzhouChina Department of Nephrology Wuhan Children’s Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science&TechnologyWuhanChina Department of Nephrology and Rheumatology Shanghai Children’s HospitalSchool

Background Pediatric antineutrophil cytoplasmic antibody-associated vasculitis(AAV)is a life-threatening systemic vasculitis featured by liability to renal ***,there are few studies on the risk factors and predictive models for renal outcomes of AAV in *** Data from 179 AAV children in multiple centers between January 2012 and March 2020 were collected *** risk factors and predictive model of end-stage renal disease(ESRD)in AAV were *** Renal involvement was the most typical manifestation(95.5%),and the crescent was the predominant pathological lesion(84.9%).The estimated glomerular filtration rate(eGFR)was evaluated in 114 patients,of whom 59.6%developed ESRD,and the median time to ESRD was 3.20 *** eGFR[P=0.006,odds ratio(OR)=0.955,95%confidence interval(CI)=0.924–0.987]and the percentages of global glomerulosclerosis(pGGS;P=0.018,OR=1.060,95%CI=1.010–1.112)were independent risk factors for ESRD of renal *** on the pGGS and eGFR at renal biopsy,we developed three risk grades of ESRD and one predictive *** Kaplan‒Meier curve indicated that renal outcomes were significantly different in different risk grades(P<0.001).Compared with serum creatinine at baseline,the predictive model had higher accuracy(0.86 versus 0.58,P<0.001)and a lower coefficient of variation(0.07 versus 0.92)in external *** Renal involvement is the most common manifestation of pediatric AAV in China,of which more than half deteriorates into *** predictive model based on eGFR at renal biopsy and the pGGS may be stable and accurate in speculating the risk of ESRD in AAV children.

关键词： Antineutrophil cytoplasmic antibody End-stage renal disease Glomerulonephritis Pediatric nephrology Vasculitis

Observation of spectral lines in the exceptional GRB 221009A

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第8期67卷 187-206页

作者： Yan-Qiu zhang Shao-Lin Xiong Ji-Rong Mao Shuang-Nan zhang Wang-Chen Xue Chao Zheng jia-Cong Liu Zhen zhang Xi-Lu Wang Ming-yu Ge Shu-Xu Yi Li-Ming Song Zheng-hua An Ce Cai Xin-Qiao Li Wen-Xi Peng Wen-Jun Tan Chen-Wei Wang Xiang-Yang Wen yue Wang Shuo Xiao Fan zhang Peng zhang Shi-Jie Zheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China yunnan Observatories Chinese Academy of SciencesKunming 650011China Center for Astronomical Mega-Science Chinese Academy of SciencesBeijing 100012China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China College of Physics and Hebei Key Laboratory of Photophysics Research and Application Hebei Normal UniversityShijiazhuang 050024China Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal UniversityGuiyang 550001China College of Electronic and Information Engineering Tongji UniversityShanghai 201804China

As the brightest gamma-ray burst ever observed,GRB 221009A provided a precious opportunity to explore spectral line *** this article,we performed a comprehensive spectroscopy analysis of GRB 221009A jointly with GECAM-C and Fermi/GBM data to search for emission and absorption *** the first time we investigated the line feature throughout this GRB including the most bright part where many instruments suffered problems,and identified prominent emission lines in multiple time *** central energy of the Gaussian emission line evolves from about 37 to 6 MeV,with a nearly constant ratio(about 10%)between the line width and central ***,we find that both the central energy and the energy flux of the emission line evolve with time as a power law decay with power law index of–1 and–2,*** suggest that the observed emission lines most likely origin from the blue-shifted electron positron pair annihilation 511 ke V *** find that a standard high latitude emission scenario cannot fully interpret the observation,thus we propose that the emission line comes from some dense clumps with electron positron pairs traveling together with the *** this scenario,we can use the emission line to directly,for the first time,measure the bulk Lorentz factor of the jet(Γ)and reveal its time evolution(i.e.,Γ~t^(-1))during the prompt ***,we find that the flux of the annihilation line in the co-moving frame keeps *** discoveries of the spectral line features shed new and important lights on the physics of GRB and relativistic jet.

关键词： GRB GRB 221009A emission line