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Effects of Different Connectivity Topologies in Small World Networks on EEG-Like Activities

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Communications in Theoretical Physics 2006年第2期45卷 373-378页

作者： lin Min zhang gui-qing chen tian-lun Department of Physics Nankai University Tianjin 300071 China

Based on our previously pulse-coupled integrate-and-fire neuron model in small world networks, we investigate the effects of different connectivity topologies on complex behavior of electroencephalographic-like signals produced by this model. We show that several times series analysis methods that are often used for analyzing complex behavior of electroencephalographic-like signals, such as reconstruction of the phase space, correlation dimension, fractal dimension, and the Hurst exponent within the rescaled range analysis （R/S）. We lind that the different connectivity topologies lead to different dynamical behaviors in models of integrate-and-fire neurons.

关键词： correlation dimension Hurst exponent small world networks

Ferroelectric artificial synapse for neuromorphic computing and flexible applications

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Fundamental Research 2023年第6期3卷 960-966页

作者： qing-Xuan Li Yi-lun Liu Yuan-Yuan Cao tian-Yu wang Hao Zhu Li Ji Wen-Jun Liu qing-qing Sun David Wei zhang lin chen State Key Laboratory of ASIC and System School of MicroelectronicsFudan UniversityShanghai 200433China National Integrated Circuit Innovation Center No.825 Zhangheng RoadShanghai 201203China

Research of artificial synapses is increasing in popularity with the development of bioelectronics and the appearance of wearable *** the high-temperature treatment process of inorganic materials is not compatible with flexible substrates,organic ferroelectric materials that are easier to process have emerged as *** organic synaptic device based on P(VDF-TrFE)was prepared in this *** device showed reliable P/E endurance over 104 cycles and a data storage retention capability at 80℃ over 104 ***,it possessed excellent synaptic functions,including short-term/long-term synaptic plasticity and spike-timing-dependent *** addition,the ferroelectric performance of the device remained stable even under bending(7 mm bending radius)or after 500 bending *** work shows that low-temperature processed organic ferroelectric materials can provide new ideas for the future development of wearable electronics and flexible artificial synapses.

关键词： Organic artificial synapse Neuromorphic computing Synaptic devices Wearable electronics Ferroelectric

AIWW:a new nutrition-screening tool for the oncologic population

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Science China(Life Sciences) 2023年第8期66卷 1831-1840页

作者： Yi-Zhong Ge Zhen-Ming Fu Qi zhang Meng-Meng Song Guo-tian Ruan Xi zhang Xiao-Wei zhang Xiang-Rui Li Kang-Ping zhang Meng Tang Xiao-Yue Liu Ming Yang Tong Liu Hai-lun Xie He-Yang zhang Zi-Wen wang Chun-Lei Hu Shi-Qi lin Rui zhang Hong-Xia Xu Wei Li Chun-Hua Song Ming Liu Jun-Qiang chen Kun-Hua wang Li Bo Ming-Hua Cong Zeng-Ning Li Zeng-Qin Guo Xiao-Bin wang Bin-Yan wang Benjamin Xu Xian-Hui Qin Xi-Ping Xu Rocco Barazzoni qing-Hua Yao Min Weng Xian Shen Han-Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group Department of Gastrointestinal Surgery/Department of Clinical Nutrition Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University Wenzhou 325000China National Clinical Research Center for Geriatric Diseases Xuanwu HospitalCapital Medical UniversityBeijing 100053China Beijing International Science and Technology Cooperation Base for Cancer Metabolism and Nutrition Beijing 100038China Key Laboratory of Cancer FSMP for State Market Regulation Beijing 100038China Cancer Center Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Colorectal Surgery Cancer Hospital of University of Chinese Academy of SciencesZhejiang Cancer HospitalHangzhou 310022China Department of Clinical Nutrition Daping HospitalArmy Medical University(Third Military Medical University)Chongqing 400042China Cancer Center of the First Hospital of Jilin University Changchun 130021China Department of Epidemiology College of Public HealthZhengzhou UniversityZhengzhou450001China Department of Colorectal Surgery the Second Affiliated Hospital of Harbin Medical UniversityHarbin 150081China Department of Gastrointestinal Surgery First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Yunnan University Kunming 650091China General Surgery Clinical Medical Center of Yunnan Province Kunming 650032China Affiliated Hospital of Yunnan University Kunming 650091China Comprehensive Oncology Department Cancer HospitalChinese Academy of Medical SciencesBeijing 100021China Department of Clinical Nutrition The First Hospital of Hebei Medical UniversityShijiazhuang 050031China Department of Medical Oncology Fujian Cancer HospitalFujian Medical University Cancer HospitalFuzhou 350014China Department of Population Family and Reproductive HealthJohns Hopkins University Bloomberg School of Public HealthBaltimore MD 21228USA Shenzhen Evergreen Medical Institute Shenzhen 518052China Department of Epid

Malnutrition is a common comorbidity among patients with ***,no nutrition-screening tool has been recognized in this population.A quick and easy screening tool for nutrition with high sensitivity and easy-to-use is *** on the previous 25 nutrition-screening tools,the Delphi method was made by the members of the Chinese Society of Nutritional Oncology to choose the most useful item from each *** to these results,we built a nutrition-screening tool named age,intake,weight,and walking(AIWW).Malnutrition was defined based on the scored patient-generated subjective global assessment(PG-SGA).Concurrent validity was evaluated using the Kendall tau coefficient and kappa consistency between the malnutrition risks of AIWW,nutritional risk screening 2002(NRS-2002),and malnutrition screening tool(MST).Clinical benefit was calculated by the decision curve analysis(DCA),integrated discrimination improvement(IDI),and continuous net reclassification improvement(c NRI).A total of 11,360 patients(male,n=6,024(53.0%)were included in the final study cohort,and 6,363 patients had malnutrition based on *** on AIWW,NRS-2002,and MST,7,545,3,469,and1,840 patients were at risk of malnutrition,*** sensitivities of AIWW,NRS-2002,and MST risks were 0.910,0.531,and 0.285,and the specificities were 0.768,0.946,and *** Kendall tau coefficients of AIWW,NRS-2002,and MST risks were 0.588,0.501,and 0.326,*** area under the curve of AIWW,NRS-2002,and MST risks were0.785,0.739,and 0.630,*** IDI,c NRI,and DCA showed that AIWW is non-inferior to NRS-2002(IDI:0.002(-0.009,0.013),c NRI:-0.015(-0.049,0.020)).AIWW scores can also predict the survival of patients with *** missed diagnosis rates of AIWW,NRS-2002,and MST were 0.09%,49.0%,and 73.2%,*** showed a better nutritionscreening effect than NRS-2002 and MST for patients with cancer and could be recommended as an alternative nutritionscreening tool

关键词： nutrition-screening AIWW NRS-2002 MST cancer

Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China

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Biomedical and Environmental Sciences 2020年第12期33卷 893-905页

作者： MA Yan ZHU Dong Shan chen Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU gui Hui YANG Pu Ye BAI Jiang Feng chen Hong chen Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui wang Jing Wei SONG Fang Li SUN Sheng wang Dong Ting wang Ming Xuan wang Xiao Yan wang Yin Zhen wang Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li zhang Gong Qi zhang Jin Bo zhang lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU tian qing zhang Hua Min wang Yan Ping wang Yong Yan 无 Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Centre for Health Management and Policy Research School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China Department of Tuberculosis The Public Health Clinical Center of ChengduChengdu 610066SichuanChina Department of Infectious Disease Shaanxi Infectious Disease HospitalXi'an 610113ShaanxiChina Department of Infectious Disease Yulin Chinese Medicine HospitalYulin 719000ShaanxiChina President's Office The First Hospital of QiqiharQiqihar 161005HeilongjiangChina Department of Traditional Chinese Medicine Shangluo Central HospitalShangluo 726000ShaanxiChina Department of Traditional Chinese Medicine The People's Hospital of QitaiheQitaihe 154603HeilongjiangChina Department of Scientific Research Xianyang Central HospitalXianyang 712000ShaanxiChina Department of traditional Chinese medicine The First Affiliated Hospital of Anhui University of Traditional Chinese MedicineHefei 230012AnhuiChina Department of Infectious Disease Heping Hospital Affiliated to Changzhi Medical CollegeChangzhi 046000ShanxiChina Department of Traditional Chinese Medicine Langfang Hospital of Chinese MedicineLangfang 065000HeibeiChina Department of Traditional Chinese Medicine Xingtai Hospital of Chinese MedicineXingtai 054001HeibeiChina Department of Traditional Chinese Medicine The People's Hospital of Guangxi Zhuang Autonomous RegionNanning 168600GuangxiChina Department of Traditional Chinese Medicine The First People'sHospital of FangchenggangFangchenggang 538001GuangxiChina Department of Traditional Chinese Medicine Mianyang Hospital of Traditional Chinese MedicineMianyang 621000SichuanChina Department of Traditional Chinese Medicine Liuzhou People's HospitalLiuzhou 545006GansuChina Department of Traditional Chinese Medici

Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains *** A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of *** Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two *** Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes.

关键词： Comorbidities COVID-19 Severity Gender Age Treatment outcome

中国东部地区典型森林类型土壤有机碳储量分析

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资源科学 2006年第2期28卷 97-103页

作者：张城王绍强于贵瑞何洪林张文娟王伯伦陈庆美吴志峰中国科学院地理科学与资源研究所生态系统网络观测与模拟重点实验室北京100101 沈阳农业大学农学院沈阳110161 广东省生态环境与土壤研究所广州510650

森林土壤有机碳(SOC)是土壤有机碳库的重要组成部分,在土壤有机碳库研究中有着重要作用。本文对中国东部地区7个典型森林的土壤样区碳储量进行了野外调查与对比研究,分析了6种土壤类型和28种植被类型的SOC储量及其随深度的变化。结果表... 详细信息

森林土壤有机碳(SOC)是土壤有机碳库的重要组成部分,在土壤有机碳库研究中有着重要作用。本文对中国东部地区7个典型森林的土壤样区碳储量进行了野外调查与对比研究,分析了6种土壤类型和28种植被类型的SOC储量及其随深度的变化。结果表明,调查区域内SOC储量的分布范围在4.01kg^30.12kg/m3之间,在各土壤类型中,长白山棕黑毡土的有机碳储量最高,SOC储量为24.41kg/m3,千烟洲红壤的有机碳储量最低,SOC储量为6.47kg±1.01kg/m3;在各植被类型中,鸡公山的黄山松林SOC储量最高,SOC储量为30.12kg±22.76kg/m3。千烟洲常绿阔叶林土壤的有机碳储量最低,SOC储量为4.01kg±3.56kg/m3,部分地区SOC储量还有一定的增长潜力。年均温与SOC储量呈负相关,但7个典型森林类型土壤碳储量的分布,在由北向南的方向上没有明显的特征。初步分析认为,土地利用类型是影响本研究所调查地区SOC储量分布的主要因子。7个典型森林类型土壤碳储量随土层深度的下降而降低,其中自然林土壤碳储量降低幅度相对较大,人工林土壤碳储量降低的幅度相对较小。人工林土壤剖面上层SOC储量相对较低,导致了人工林土壤整体有机碳储量比较低。

关键词：中国东部典型森林土壤有机碳储量

低温促进表面等离激元共振效应及肌酐的超灵敏表面增强拉曼散射探测

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物理学报 2022年第14期71卷 182-191页

作者：厉桂华张梦雅马慧田悦焦安欣郑林启王畅陈明刘向东李爽崔清强李冠华山东农业大学信息科学与工程学院泰安271018 山东大学物理学院济南250100 山东大学齐鲁医学院济南市中心医院呼吸与危重症医学科济南250100 山东建筑大学理学院济南250100

肌酐是肾脏疾病诊断和监测的关键生物标志物,因此,快速、灵敏的肌酐检测非常重要.本文提供了一种通过提高低温下的光子诱导电荷转移效率来促进表面增强拉曼散射光谱(SERS)活性的有效策略.采用种子生长法获得纳米金二十面体(Au_(20)),以... 详细信息

肌酐是肾脏疾病诊断和监测的关键生物标志物,因此,快速、灵敏的肌酐检测非常重要.本文提供了一种通过提高低温下的光子诱导电荷转移效率来促进表面增强拉曼散射光谱(SERS)活性的有效策略.采用种子生长法获得纳米金二十面体(Au_(20)),以此作为SERS活性基底.采用极低温(98 K)SERS检测技术实现对染料分子结晶紫(CV)和生理盐水中的肌酐含量的快速、灵敏检测.实验结果表明:常温296 K下,Au_(20)基底对CV分子的检测限(LOD)低至10^(-12) mol/L,并且信号均匀;低温98 K时,CV分子的LOD可达10^(-14) mol/L,比296 K时降低2个数量级.最后,使用Au20基底对生理盐水中的肌酐进行无标记检测.结果表明,常温296 K时该SERS基底对肌酐的LOD为10^(-6) mol/L,1619 cm^(-1)峰的线性相关系数为0.9839.低温98 K时,肌酐的浓度探测极限低至10^(-8) mol/L,1619 cm^(-1)峰的线性相关系数变为0.9973.可知,低温使肌酐浓度检测限和特征峰线性度都进一步提高.本文的工作为生物医药领域肌酐浓度的精确检测提供了新的思路.

关键词：低温表面增强拉曼散射肌酐超灵敏检测

基于聚龙一号装置的超高速飞片发射实验研究进展

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物理学报 2014年第19期63卷 262-272页

作者：王贵林郭帅沈兆武张朝辉刘仓理李军章征伟贾月松赵小明陈宏丰树平计策夏明鹤卫兵田青李勇丁瑜郭帆中国科学技术大学近代力学系合肥230027 中国工程物理研究院流体物理研究所中物院脉冲功率科学与技术重点实验室绵阳621900

磁驱动加载技术通过脉冲功率源将超大脉冲电流加载到实验负载区,从而形成随时间平滑上升的磁压力,实现对样品的准等熵压缩和超高速飞片发射.本文基于聚龙一号装置的输出特性参数,依次从负载结构、电极尺寸、电流波形和诊断系统等方面,... 详细信息

磁驱动加载技术通过脉冲功率源将超大脉冲电流加载到实验负载区,从而形成随时间平滑上升的磁压力,实现对样品的准等熵压缩和超高速飞片发射.本文基于聚龙一号装置的输出特性参数,依次从负载结构、电极尺寸、电流波形和诊断系统等方面,分别设计完成了两种负载构型的超高速飞片发射实验.其中应用单侧带状负载发射尺寸Φ10 mm×0.725 mm的LY12铝飞片速度达到11.5 km/s,磁驱动加载压力近0.9 Mbar.比较模拟计算与实验结果,飞片发射过程和最终速度基本一致.而进一步的模拟计算表明,优化的负载结构尺寸和电流波形调节方案下,将有望发射尺寸Φ8.5 mm×1 mm的铝飞片速度超过15 km/s.从模拟设计到实验开展,已初步掌握了基于多支路脉冲功率发生器的超高速飞片发射实验技术.

关键词：磁驱动加载超高速飞片发射单侧带状负载准等熵

膨胀石墨的制备及其对煤炭地下气化煤气冷凝水的净化

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硅酸盐通报 2018年第9期37卷 2722-2728页

作者：田启明邢宝林徐冰谌伦建李郑鑫史长亮李春铜王长园姚友恒张青山河南理工大学化学化工学院河南省煤炭绿色转化重点实验室焦作454003 煤炭安全生产河南省协同创新中心焦作454003 焦作市环境保护局焦作454000

以天然石墨为原料,采用化学氧化-高温膨胀工艺制备膨胀石墨,利用扫描电镜、低温氮气物理吸附仪和红外光谱仪对膨胀石墨的表面形貌、孔结构特征及表面官能团等微观结构进行表征;并系统研究其对内蒙古褐煤地下气化煤气冷凝水中氨氮(NH3-N... 详细信息

以天然石墨为原料,采用化学氧化-高温膨胀工艺制备膨胀石墨,利用扫描电镜、低温氮气物理吸附仪和红外光谱仪对膨胀石墨的表面形貌、孔结构特征及表面官能团等微观结构进行表征;并系统研究其对内蒙古褐煤地下气化煤气冷凝水中氨氮(NH3-N)和总有机碳(TOC)的吸附净化特性。结果表明,所制膨胀石墨具有片层状三维网络结构,孔隙发达,比表面积可达27.3 m^2·g^(-1),总孔容为0.124 cm^3·g^(-1),孔径主要分布在2~10 nm,且其表面含有丰富的羰基、酚羟基等含氧官能团,是一种性能优良的介孔吸附材料。膨胀石墨对煤炭地下气化煤气冷凝水中NH_3-N和TOC具有良好的净化效果;当膨胀石墨添加量为1.5 g,吸附温度为40℃,振荡吸附时间为60 min的工艺条件下,膨胀石墨对煤气冷凝水中NH_3-N的脱除率和吸附量分别为44.35%和8.76 mg·g^(-1),TOC的脱除率和吸附量则分别为59.80%和4.07 mg·g^(-1)。

关键词：膨胀石墨煤炭地下气化煤气冷凝水氨氮总有机碳吸附净化

基于HPLC指纹图谱考察3种复合掩味佐剂对御寒颗粒汤剂成分的影响

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中华中医药杂志 2018年第3期33卷 1128-1134页

作者：姚静施钧瀚桂新景王青晓张璐康冰亚陈鹏举田亮玉李学林刘瑞新河南中医药大学第一附属医院郑州450000 河南中医药大学郑州450046 河南省食品药品检验所郑州450008

目的:探究3种复合掩味佐剂——咖啡味中药伴侣、巧克力味中药伴侣、甜橙味中药伴侣掩味前后御寒颗粒汤剂中化学成分的变化,揭示3种复合掩味佐剂对御寒颗粒汤剂的化学成分的影响。方法:以单味配方颗粒组成的御寒颗粒方为苦味载体,采用高... 详细信息

目的:探究3种复合掩味佐剂——咖啡味中药伴侣、巧克力味中药伴侣、甜橙味中药伴侣掩味前后御寒颗粒汤剂中化学成分的变化,揭示3种复合掩味佐剂对御寒颗粒汤剂的化学成分的影响。方法:以单味配方颗粒组成的御寒颗粒方为苦味载体,采用高效液相色谱法参考指纹图谱技术建立其化学成分的特征图谱测定方法,以掩味前后共有峰相对保留时间、相对峰面积的变化率以及总峰面积为指标,比较御寒颗粒汤剂掩味前后化学成分的变化。结果:掩味前后的御寒颗粒汤剂,特征图谱共有峰有22个,与原液相比,加入3类中药伴侣后的样品的共有峰相对保留时间变化率的绝对值均值分别为(0.18±0.04)%、(0.11±0.04)%、(0.17±0.06)%,均<0.2%;共有峰相对峰面积变化率的绝对值均值甜橙味为(1.81±1.26)%,<5%;咖啡味和巧克力味相对峰面积的变化率绝对值用中位数(四分位数间距)表示分别为:2.30%(1.45%-3.99%)、3.73%(2.70%-6.68%);与原液相比,总峰面积均无显著性差异。结论:3种复合掩味佐剂中,甜橙味对御寒颗粒汤剂的化学成分几乎没有影响;咖啡味和巧克力味对其汤剂的某些成分有微小的影响,但对其汤剂中化学成分的总量无显著影响,是否会影响到其汤剂的药效有待进一步临床药效学方面的研究。

关键词：复合掩味佐剂御寒颗粒掩味高效液色谱特征图谱