AIWW:a new nutrition-screening tool for the oncologic population

作     者：Yi-Zhong Ge Zhen-Ming Fu Qi Zhang Meng-Meng Song Guo-Tian Ruan Xi Zhang Xiao-Wei Zhang Xiang-Rui Li Kang-Ping Zhang Meng Tang Xiao-Yue Liu Ming Yang Tong Liu Hai-Lun Xie He-Yang Zhang Zi-Wen Wang Chun-Lei Hu Shi-Qi Lin Rui Zhang Hong-Xia Xu Wei Li Chun-Hua Song Ming Liu Jun-Qiang Chen Kun-Hua Wang Li Bo Ming-Hua Cong Zeng-Ning Li Zeng-Qin Guo Xiao-Bin Wang Bin-Yan Wang Benjamin Xu Xian-Hui Qin Xi-Ping Xu Rocco Barazzoni Qing-Hua Yao Min Weng Xian Shen Han-Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group 

作者机构：Department of Gastrointestinal Surgery/Department of Clinical NutritionBeijing Shijitan HospitalCapital Medical UniversityBeijing 100038China The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325000China National Clinical Research Center for Geriatric DiseasesXuanwu HospitalCapital Medical UniversityBeijing 100053China Beijing International Science and Technology Cooperation Base for Cancer Metabolism and NutritionBeijing 100038China Key Laboratory of Cancer FSMP for State Market RegulationBeijing 100038China Cancer CenterRenmin Hospital of Wuhan UniversityWuhan 430060China Department of Colorectal SurgeryCancer Hospital of University of Chinese Academy of SciencesZhejiang Cancer HospitalHangzhou 310022China Department of Clinical NutritionDaping HospitalArmy Medical University(Third Military Medical University)Chongqing 400042China Cancer Center of the First Hospital of Jilin UniversityChangchun 130021China Department of EpidemiologyCollege of Public HealthZhengzhou UniversityZhengzhou450001China Department of Colorectal Surgerythe Second Affiliated Hospital of Harbin Medical UniversityHarbin 150081China Department of Gastrointestinal SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Yunnan UniversityKunming 650091China General Surgery Clinical Medical Center of Yunnan ProvinceKunming 650032China Affiliated Hospital of Yunnan UniversityKunming 650091China Comprehensive Oncology DepartmentCancer HospitalChinese Academy of Medical SciencesBeijing 100021China Department of Clinical NutritionThe First Hospital of Hebei Medical UniversityShijiazhuang 050031China Department of Medical OncologyFujian Cancer HospitalFujian Medical University Cancer HospitalFuzhou 350014China Department of PopulationFamily and Reproductive HealthJohns Hopkins University Bloomberg School of Public HealthBaltimore MD 21228USA Shenzhen Evergreen Medical InstituteShenzhen 518052China Department of EpidemiologyHarvard T.H.Chan School of Public HealthBoston MA 02115USA National Clinical Research Center for Kidney DiseaseState Key Laboratory for Organ Failure ResearchRenal DivisionNanfang HospitalSouthern Medical UniversityGuangzhou 510515China Beijing Advanced Innovation Center for Food Nutrition and Human HealthCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100193China Department of MedicalSurgical and Health SciencesUniversity of TriesteTrieste 34127Italy Department of Integrated Chinese and Western MedicineCancer Hospital of University of Chinese Academy of SciencesZhejiang Cancer HospitalHangzhou 310022China Department of Clinical NutritionThe First Affiliated Hospital of Kunming Medical UniversityKunming 650091China Department of Gastrointestinal Surgerythe Second Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000China 不详 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2023年第66卷第8期

页      面：1831-1840页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100214[医学-肿瘤学] 100215[医学-康复医学与理疗学] 10[医学] 

基　　金：supported by the Key Research and Development Program of Beijing Municipal Science and Technology Commission(D181100000218004) General Surgery Clinical Medical Center of Yunnan Province(ZX2019-03-03) the National Key Research and Development Program of China(2022YFC2009600) 

主　　题：nutrition-screening AIWW NRS-2002 MST cancer 

摘      要：Malnutrition is a common comorbidity among patients with ***,no nutrition-screening tool has been recognized in this population.A quick and easy screening tool for nutrition with high sensitivity and easy-to-use is *** on the previous 25 nutrition-screening tools,the Delphi method was made by the members of the Chinese Society of Nutritional Oncology to choose the most useful item from each *** to these results,we built a nutrition-screening tool named age,intake,weight,and walking(AIWW).Malnutrition was defined based on the scored patient-generated subjective global assessment(PG-SGA).Concurrent validity was evaluated using the Kendall tau coefficient and kappa consistency between the malnutrition risks of AIWW,nutritional risk screening 2002(NRS-2002),and malnutrition screening tool(MST).Clinical benefit was calculated by the decision curve analysis(DCA),integrated discrimination improvement(IDI),and continuous net reclassification improvement(c NRI).A total of 11,360 patients(male,n=6,024(53.0%)were included in the final study cohort,and 6,363 patients had malnutrition based on *** on AIWW,NRS-2002,and MST,7,545,3,469,and1,840 patients were at risk of malnutrition,*** sensitivities of AIWW,NRS-2002,and MST risks were 0.910,0.531,and 0.285,and the specificities were 0.768,0.946,and *** Kendall tau coefficients of AIWW,NRS-2002,and MST risks were 0.588,0.501,and 0.326,*** area under the curve of AIWW,NRS-2002,and MST risks were0.785,0.739,and 0.630,*** IDI,c NRI,and DCA showed that AIWW is non-inferior to NRS-2002(IDI:0.002(-0.009,0.013),c NRI:-0.015(-0.049,0.020)).AIWW scores can also predict the survival of patients with *** missed diagnosis rates of AIWW,NRS-2002,and MST were 0.09%,49.0%,and 73.2%,*** showed a better nutritionscreening effect than NRS-2002 and MST for patients with cancer and could be recommended as an alternative nutritionscreening tool