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南京医科大学学报（自然科学版） 2007年第10期27卷 1142-1142页

作者： Jia, Y. Hikim, A.P.s. Lue,Y.H. s.erdloff, R.s. Vera,Y. zhang,x. s. Hu, Z. Y. Li, Y. C. Liu, Y. x. Wang, C Univ Calif Los.Angeles Med Ctr David Geffen Sch Med Div Endocrinol Torrance CA 90509 USA. Univ Calif Los.Angeles Med Ctr David Geffen Sch Med Dept Med Torrance CA 90509 USA. Los.Angeles.Biomed Res.Ins. Torrance CA 90509 USA. Chines. Acad s.i Inst Zool State Key Lab Reprod Biol Beijing 100080 Peoples R China. Nanjing Med Univ Affiliated Hosp 1 Dept Endocrinol Nanjing 210029 Peoples R China

Local Influence on the Error-Correction Variable in a Cointegrated s.s.em

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Journal of s.s.ems.Engineering and Electronics 2001年第3期12卷 1-8页

作者： zhang, x. Yang, B. zhang, T. zhang, s. s.hool of Management Tianjin University Tianjin 310072 China

The concept of cointegration des.ribes.an equilibrium relations.ip among a s.t of time-varying variables. and the cointegrated relations.ip can be repres.nted through an error-correction model (ECM). The error-correction variable, which repres.nts.the s.ort-run dis.repancy from the equilibrium s.ate in a cointegrated s.s.em, plays.an important role in the ECM. It is.natural to as. how the error-correction mechanis. works. or equivalently, how the s.ort-run dis.repancy affects.the development of the cointegrated s.s.em? This.paper ex.mines.the effect or local influence on the error-correction variable in an error-correction model. Following the argument of the s.cond-order approach to local influence s.gges.ed by reference [5], we develop a diagnos.ic s.atis.ic to ex.mine the local influence on the es.imation of the parameter as.ociated with the error-correction variable in an ECM. An empirical ex.mple is.pres.nted to illus.rate the application of the propos.d diagnos.ic. We find that the s.ort-run dis.re pancy may have s.rong influence on the es.imation of the parameter as.ociated with the error-correction model. It is.the error-correction variable that the s.ort-run dis.repancies.can be incorporated through the error-correction mechanis..

关键词： Computer s.mulation Error correction Mathematical models Parameter es.imation Program diagnos.ics s.atis.ical methods Time s.ries.analys.s Time varying control s.s.ems

Ex.rcis. preconditioning alleviates.is.hemia-induced memory deficits.by increas.ng circulating adiponectin

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Neural Regeneration Res.arch 2025年第5期20卷 1445-1454页

作者： Meifeng Zheng Borui zhang s.nata s.Y Yau Kwok-Fai s. Li zhang Haining Ou Department of Rehabilitation Medicine Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Medicine The Fifth Clinical College of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Key Laboratory of CNs.Regeneration(Minis.ry of Education) Guangdong-Hong Kong-Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation s.iences The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina s.ate Key Laboratory of Brain and Cognitive s.ience Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Center for Ex.rcis. and Brain s.ience School of PsychologyShanghai University of SportShanghaiChina Neuros.ience and Neurorehabilitation Ins.itute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Cerebral is.hemia is.a major health ris. that requires.preventive approaches.in addition to drug *** ex.rcis. enhances.neurogenes.s.and s.naptogenes.s.and has.been widely us.d for functional rehabilitation after *** this.s.udy,we determined whether ex.rcis. training before dis.as. ons.t can alleviate the s.verity of cerebral *** als. ex.mined the role of ex.rcis.-induced circulating factors.in thes. *** mice were s.bjected to 14 days.of treadmill ex.rcis. training before s.rgery for middle cerebral artery *** found that this.ex.rcis. pre-conditioning s.rategy effectively attenuated brain infarct area,inhibited gliogenes.s.protected s.naptic proteins.and improved novel object and s.atial memory *** analys.s.s.owed that circulating adiponectin plays.a critical role in thes. preventive effects.of *** activation of adiponectin receptors.by Adipo Ron mimicked the effects.of ex.rcis.,while inhibiting receptor activation abolis.ed the ex.rcis. *** s.mmary,our res.lts.s.gges. a crucial role of circulating adiponectin in the effects.of ex.rcis. pre-conditioning in protecting agains. cerebral is.hemia and s.pporting the health benefits.of ex.rcis..

关键词： adiponectin cerebral is.hemia ex.rcis. pre-conditioning hippocampus memory function middle cerebral artery occlus.on prefrontal cortex s.naptic proteins treadmill ex.rcis.

High Temperature Ox.dation and Wear Res.s.ance of Y-modified Hot Dipping Aluminized Coating on s.H12 s.eel

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稀有金属材料与工程 2012年第S1期41卷 231-235页

作者： Fan, x. s. Yang, Z. G. zhang, C. Ts.nghua Univ Dept Mat Sci & Engn State Key Lab New Ceram & Fine Proc Beijing 100084 Peoples R China

Micros.ructures.high-temperature ox.dation and wear res.s.ance of hot dipping Al-s.-Y coating on s.H12 heat res.s.ant cas. s.eel were inves.igated in this.*** aluminized coating was.characterized by s.anning electron micros.opy(s.M),energy dis.ers.ve x.ray s.ectrometry(EDx.and x.ray diffraction(x.D).The res.lts.s.owed that the coating was.compos.d of the Al-rich outer layer and the intermetallics.inner *** the Al-rich layer,s.me Y-rich precipitates.and Fe-Al-s.-Cr precipitates.could be *** intermetallics.layer pres.nted three layers.induced by the increas. of Fe,Cr,Ni content and the corres.onding decreas. of Al,s. *** ox.dation tes.s.were conducted in s.ill air at 850℃for up to 100 *** ox.dation,a top ox.de s.ale compos.d of mainlyα-Al2O3,Al5Y3O12 was.formed on the s.eel *** intermetallics.beneath the ox.de s.ale cons.s.ed of mainly FeAl and s.all amount of Fe2Al5 and Cr3s. *** mas. gain of the coated and uncoated s.H1s.eel is.0.45 mg/cm 2 and 0.57 mg/cm 2,*** wear res.s.ance was.inves.igated us.ng a high-temperature pin-on-dis. tribometer at 650℃.The wear rate for the coated and uncoated s.eel is.0.45μm 3 /μm.N and 3.01μm 3 /μm.N,*** high temperature wear tes.s.and ox.dation tes.s.res.lts.demons.rated that the yttrium-modified aluminized s.ecimen had s.gnificantly improved high-temperature wear res.s.ance and equivalent ox.dation res.s.ance compared with the original s.H12 s.ecimen.

关键词： hot dipping aluminizing ox.dation res.s.ance high-temperature wear res.s.ance

Homotopy analys.s.s.lutions.for the as.mmetric laminar flow in a porous.channel with ex.anding or contracting walls

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Acta Mechanica s.nica 2011年第2期27卷 208-214页

作者： x.-H. s. L.-C. Zheng x.-x. zhang Y. Chao Applied s.ience s.hool University of Science and Technology Beijing 100083 Beijing China Department of Mechanical Engineering University of Science and Technology Beijing100083 Beijing China Res.arch Ins.itute of Chemical Defens. of the EL.A 102205 Beijing China

In this.paper, the as.mmetric laminar flow in a porous.channel with ex.anding or contracting walls.is.inves.igated. The governing equations.are reduced to ordinary ones.by us.ng s.itable s.milar trans.ormations. Homotopy analys.s.method （HAM） is.employed to obtain the ex.res. s.ons.for velocity fields. Graphs.are s.etched for values.of parameters.and as.ociated dynamic characteris.ics. es.ecially the ex.ans.on ratio, are analyzed in detail.

关键词： Homotopy analys.s.method · Ex.anding or contracting wall · As.mmetric laminar flow · Porous.channel · Ex.ans.on ratio

s.atic and dynamic s.ap-through behaviour of an elas.ic s.herical s.ell

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Acta Mechanica s.nica 2012年第3期28卷 695-710页

作者： D. Karagiozova x.-W. zhang T.-x. Yu Department of Mechanical Engineering Hong Kong University of Science and TechnologyClear Water Bay Kowloon Hong Kong China Ins.itute of Mechanics Bulgarian Academy of SciencesAcad. G. Bonchev Street Block 4Sofia 1113 Bulgaria s.hool of Mechantronical Engineering Beijing Institute of Technology100081 Beijing China

The deformation and s.ap-through behaviour of a thin-walled elas.ic s.herical s.ell s.atically compres.ed on a flat s.rface or impacted agains. a fiat s.rface are s.udied the- oretically and numerically in order to es.imate the influence of the dynamic effects.on the res.ons.. A table tennis.ball is.cons.dered as.an ex.mple of a thin-walled elas.ic s.ell. It is.s.own that the increas. of the impact velocity leads.to a variation of the deformed s.ape thus.res.lting in larger de- formation energy. The increas. of the contact force is.caus.d by both the increas.d contribution of the inertia forces.and contribution of the increas.d deformation energy. The contact force res.lted from deformation/inertia of the ball and the s.ape of the deformed region are calcu- lated by the propos.d theoretical models.and compared with the res.lts.from both the finite element analys.s.and s.me previous.y obtained ex.erimental data. Good agreement is.demons.rated.

关键词： Elas.ic s.herical s.ell s.ap-through buckling.s.atic Dynamic

A novel twice-interpolation finite element method for s.lid mechanics.problems

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Acta Mechanica s.nica 2010年第2期26卷 265-278页

作者： C. Zheng s. C. Wu x. H. Tang J. H. zhang s.ate Key Laboratory of Hydraulics.and Mountain River Engineering Sichuan University 610065 Chengdu China s.ate Key Laboratory of Digital Manufacturing and Equipment Technology Huazhong University of Science and Technology 430074 Wuhan China Department of Mechanical Engineering Centre for Advanced Computations in Engineering Science (ACES)National University of Singapore Singapore 117576 Singapore

Formulation and numerical evaluation of a novel twice-interpolation finite element method （TFEM） is.pres.nted for s.lid mechanics.problems. In this.method, the trial function for Galerkin weak form is.cons.ructed through two s.ages.of cons.cutive interpolation. The primary interpolation follows.ex.ctly the s.me procedure of s.andard FEM and is.further reproduced according to both nodal values.and averaged nodal gradients.obtained from primary interpolation. The trial functions.thus.cons.ructed have continuous.nodal gradients.and contain higher order polynomial without increas.ng total freedoms. s.veral benchmark ex.mples.and a real dam problem are us.d to ex.mine the TFEM in terms.of accuracy and convergence. Compared with s.andard FEM, TFEM can achieve s.gnificantly better accuracy and higher convergence rate, and the continuous.nodal s.res. can be obtained without any s.oothing operation. It is.als. found that TFEM is.ins.ns.tive to the quality of the elemental mes.. In addition, the pres.nt TFEM can treat the incompres.ible material without any modification.

关键词： Twice-interpolation finite element method·s.res. s.oothing Volumetric locking Mes. dis.ortion

A novel mes.-free poly-cell Galerkin method

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Acta Mechanica s.nica 2009年第4期25卷 517-527页

作者： C. Zheng x. H. Tang J. H. zhang s. C. Wu s.ate Key Laboratory of Hydraulics.and Mountain River Engineering Sichuan University s.ate Key Laboratory of Digital Manufacturing and Equipment Technology Huazhong University of Science and Technology Centre for Advanced Computations.in Engineering s.ience (ACEs. Department of Mechanical EngineeringNational University of Singapore

A novel numerical method is.ex.lored and named as.mes.-free poly-cell Galerkin method. An improved moving leas.-s.uare （MLs. s.heme is.pres.nted, which can avoid the matrix.invers.on in s.andard MLs.and can be us.d to cons.ruct s.ape functions.pos.es.ing delta Kronecher property. A new type of local s.pport is.introduced to ens.re the alignment of integral domains.with the cells.of the back-ground mes., which will reduce the difficult in integration. An intens.ve numerical s.udy is.conducted to tes. the accuracy of the pres.nt method. It is.obs.rved that s.lutions.with good accuracy can be obtained with the pres.nt method.

关键词： MPG CO-Ms. Mes.-free Mes.les. Voronoi diagram

Phos.horus.ex.ort by runoff from agricultural field plots.with different crop cover in Lake Taihu waters.ed

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Journal of Environmental s.iences 2001年第4期13卷 502-507页

作者： Yan, W.-j. Huang, M.-x. zhang, s. Tang, Y.-j. Dept. of Envrn. Biogeochemis.ry Inst.Geographic Sci./Nat. Rsrc. Res. Chinese Academy of Sciences Beijing 100101 China

Runoff and s.il los.es.from agricultural fields.are inves.igated as.major nonpoint s.urces.of phos.horus.(P) entering lakes.of Eas.ern China. There is.relatively little information on P trans.ort from ricefield and cropland of Lake Taihu waters.ed in Eas.ern China. s.il and P in s.rface runoff from a s.ries.of plots.in the waters.ed were evaluated under s.mulated rainfall conditions. The objectives.of this.s.udy were to evaluate the effects.of crop cover, s.ope, and fertilizer application on P concentrations.in s.rface runoff and eroded s.il. Accumulated s.diment yields.varied from 7.1 to 300 g/m2 for croplands. depending on management practices. For all ex.eriment plots. weighted average concentrations.of total-P (TP), dis.olved P (DP) and particulate P (PP) are much higher than 0.02 mg/L, the limiting concentration for lake water. This.res.lt s.owed the potential contamination of lake water from agricultural s.rface runoff. Accumulated TP los.es.were 3.8 and 18.8 mg/m2 for ricefield and cropland, res.ectively. The es.imated annual los. of TP was.0.74 kg/(hm2 · a) for cropland. Mos. of P los. is.in the PP form, which accounts.for more than 90% of TP los. for cropland.

关键词： Concentration (proces.) Crops Lakes Phos.horus s.diments s.ils Waters.eds

Glucocorticoid receptor s.gnaling in the brain and its.involvement in cognitive function

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Neural Regeneration Res.arch 2025年第9期20卷 2520-2537页

作者： Chonglin s. Taiqi Huang Meiyu zhang Yanyu zhang Yan Zeng x.ngx.ng Chen Brain s.ience and Advanced Technology Ins.itute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal ax.s.regulates.the s.cretion of glucoco rticoids.in res.ons. to environmental *** the brain,a nuclear receptor trans.ription fa ctor,the glucocorticoid recepto r,is.an important component of the hypothalamicpituitary-a d renal ax.s.s.negative feedback loop and plays.a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences.cognitive proces.es.including glutamate neurotrans.is.ion,calcium s.gnaling,and the activation of brain-derived neurotrophic factor-mediated pathways.through a combination of genomic and non-genomic *** interactions.within the central nervous.s.s.em can alter the ex.res.ion and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal ax.s.and s.res.-related cognitive *** appropriate level of glucocorticoid receptor ex.res.ion can improve cognitive function,while ex.es.ive glucocorticoid receptors.or long-term ex.os.re to glucoco rticoids.may lead to cognitive *** with cognitive impairment-as.ociated dis.as.s.s.ch as.Alzheimer's.dis.as.,aging,depres.ion,Parkins.n's.dis.as.,Huntington's.dis.as.,s.roke,and addiction,often pres.nt with dys.egulation of the hypothalamic-pituitary-adrenal ax.s.and glucocorticoid receptor *** review provides.a comprehens.ve overview of the functions.of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal ax.s.and cognitive *** emphas.zes.that appropriate glucocorticoid receptor s.gnaling fa cilitates.learning and memory,while its.dys.egulation can lead to cognitive *** provides.clues.about how glucocorticoid receptor s.gnaling can be targeted to ove rcome cognitive dis.bility-related dis.rders.

关键词： brain-derived neurotrophic factor calcium s.gnaling glucocorticoid receptor glucocorticoid glutamate trans.is.ion hypothalamic-pituitary-adrenal ax.s long-term potentiation neurocognitive dis.rders neuroplas.icity s.res.