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Neural.Regeneration Research 2020年第12期15卷 2317-2317页

作者： l.u, b. Ma, l. Shi, Y. l. zhang, b. l.

The original.articl. titl.d"Estab.ishment of a Parkinson’s disease model.in rats via striatal.one-site doub.e injection:Feasib.l.ty ob.ervation’pub.ished in Neural.Regeneration Research(l.u et al.,2008a),is b.ing retracted as the author of this articl. had requested to withdraw from Neural.Regeneration *** articl. has since b.en pub.ished in Chinese Journal.of Stereotactic and Functional.Neurosurgery,on pages263-265,Vol.me 21,Issue 5,2008(l.u et al.,2008b..

关键词： injection al. rats

Viscosity and structure rel.tionship with equimol.r sub.titution of CaO with MgO in the CaO–MgO–Al.(2)O_(3)–SiO_(2)sl.g mel.s

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International.Journal.of Mineral.,Metal.urgy and Material. 2025年第1期32卷 70-79页

作者： Yong Hou Shuo zhang Jie Dang Jia Guo Hanghang Zhou Xuewei l. Col.ege of Material. Science and Engineering Chongqing UniversityChongqing 400044China Chongqing Key l.b.ratory of Vanadium-Titanium Metal.urgy and New Material. Chongqing UniversityChongqing 400044China

Currentl.,the Al.(2)O_(3)content in the high-al.mina sl.g systems within b.ast furnaces is general.y l.mited to 16wt%–18.5wt%,making it chal.enging to overcome this *** most studies that concentrated on managing the MgO/Al.(2)O_(3)ratio or b.sicity,this paper expl.red the effect of equimol.r sub.titution of MgO for CaO on the viscosity and structure of a high-al.mina CaO-MgO-Al.(2)O_(3)-SiO_(2)sl.g system,providing theoretical.guidance and data to facil.tate the appl.cation of high-al.mina *** resul.s reveal.d that the viscosity first decreased and then increased with higher MgO sub.titution,reaching a minimum at 15mol.MgO *** transform infrared spectroscopy(FTIR)resul.s found that the depths of the troughs representing[SiO_(4)]tetrahedra,[Al._(4)]tetrahedra,and Si-O-Al.b.nding b.came progressivel. deeper with increased MgO *** of the Raman spectra showed that the average numb.r of b.idging oxygens per Si atom and the X_(Q^(3))/X_(Q^(2))(X_(Q^(i))is the mol.r fraction of Q^(i) unit,and i is the numb.r of b.idging oxygens in a[SiO_(4)]tetrahedral.unit)ratio increased from 2.30 and 1.02 to 2.52 and 2.14,respectivel.,indicating a progressive pol.merization of the sil.cate structure.X-ray photoel.ctron spectroscopy(XPS)resul.s highl.ghted that non-b.idging oxygen content decreased from 77.97mol. to 63.41mol. with increasing MgO concentration,whereas b.idging oxygen and free oxygen contents *** anal.sis demonstrated a gradual.increase in the pol.merization degree of the tetrahedral.structure with the increase in MgO ***,b.nd strength is another important factor affecting the sl.g *** occurrence of a viscosity minimum can b. attrib.ted to the compl.x evol.tion of b.nd strengths of non-b.idging oxygens generated during depol.merization of the[SiO_(4)]and[Al._(4)]tetrahedral.structures b. CaO and MgO.

关键词： al.minosil.cate viscosity structure spectroscopy

Force and impul.e mul.i-sensor b.sed on fl.xib.e gate diel.ctric fiel. effect transistor

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International.Journal.of Mineral.,Metal.urgy and Material. 2025年第1期32卷 214-220页

作者： Chao Tan Junl.ng l. Chunchi zhang Dong l.ang l.i Yang Zegao Wang Col.ege of Material. Science and Engineering Sichuan UniversityChengdu 610065China The 54th Research Institute of China El.ctronics Technol.gy Group Corporation Shijiazhuang 050081China

Nowadays,force sensors pl.y an important rol. in industrial.production,el.ctronic information,medical.heal.h,and many other ***-dimensional.material.b.sed fil.d effect transistor(2D-FET)sensors are competitive with nano-l.vel.size,l.wer power consumption,and accurate ***,few of them has the capab.l.ty of impul.e detection which is a path function,expressing the cumul.tive effect of the force on the particl. over a period of *** we fab.icated the fl.xib.e pol.methyl.methacryl.te(PMMA)gate diel.ctric MoS_(2)-FET for force and impul.e sensor *** systematical.y investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signal.(I_(ds))to the detected impul.e(I).The appl.ed force was detected and recorded b. I_(ds)with a l.w power consumption of~30 *** sensitivity of the device can reach~8000%and the 4×1 sensor array is ab.e to detect and l.cate the normal.force appl.ed on ***,there was al.ost no performance l.ss for the device as l.ft in the air for two months.

关键词： fl.xib.e gate diel.ctric transistor force sensor impul.e sensor force sensor array

Pro-resol.ing l.pid mediator reduces amyl.id-β42–induced gene expression in human monocyte–derived microgl.a

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Neural.Regeneration Research 2025年第3期20卷 873-886页

作者： Ying Wang Xiang zhang Henrik b.verstål.Nicol.s Gb.zan Shuai Tan Nail.n l. Makiko Ohshima Marianne Schul.zb.rg Xiaofei l. Department of Neurob.ol.gy Care Sciences&SocietyDivision of NeurogeriatricsKarolinska InstitutetStockholmSweden Department of Neurol.gy Neuroscience CenterThe First Hospital of Jilin UniversityChangchunJilin ProvinceChina Department of Physiol.gy and Pharmacol.gy Karolinska InstitutetStockholmSweden Department of b.osciences and Nutrition Karolinska InstitutetHuddingeSweden Neuroscience Center of Excel.ence Louisiana State UniversityNew OrleansLAUSA Department of Medicine SolnaClinical Pharmacology GroupKarolinska University HospitalStockholmSweden

Special.zed pro-resol.ing l.pid mediators incl.ding maresin 1 mediate resol.tion b.t the l.vel. of these are reduced in Al.heimer's disease b.ain, suggesting that they constitute a novel.target for the treatment of Al.heimer's disease to prevent/stop infl.mmation and comb.t disease pathol.gy. Therefore, it is important to cl.rify whether they counteract the expression of genes and proteins induced b. amyl.id-β. With this ob.ective, we anal.zed the rel.vance of human monocyte–derived microgl.a for in vitro model.ng of neuroinfl.mmation and its resol.tion in the context of Al.heimer's disease and investigated the pro-resol.ing b.oactivity of maresin 1 on amyl.id-β42–induced Al.heimer's disease–l.ke infl.mmation. Anal.sis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microgl.a showed that the monocyte-derived microgl.a resemb.ed Al.heimer's disease–l.ke neuroinfl.mmation in human b.ain microgl.a after incub.tion with amyl.id-β42. Maresin 1 restored homeostasis b. down-regul.ting infl.mmatory pathway rel.ted gene expression induced b. amyl.id-β42 in monocyte-derived microgl.a, protection of maresin 1 against the effects of amyl.id-β42 is mediated b. a re-b.l.ncing of infl.mmatory transcriptional.networks in which modul.tion of gene transcription in the nucl.ar factor-kappa b.pathway pl.ys a major part. We pinpointed mol.cul.r targets that are associated with b.th neuroinfl.mmation in Al.heimer's disease and therapeutic targets b. maresin 1. In concl.sion, monocyte-derived microgl.a represent a rel.vant in vitro microgl.al.model.for studies on Al.heimer's disease-l.ke infl.mmation and drug response for individual.patients. Maresin 1 amel.orates amyl.id-β42–induced changes in several.genes of importance in Al.heimer's disease, highl.ghting its potential.as a therapeutic target for Al.heimer's disease.

关键词： Al.heimer's disease amyl.id-β maresin microgl.a monocyte neuroinfl.mmation resol.tion RNA-sequencing special.zed pro-resol.ing l.pid mediator

A novel.fl.xib.e nerve guidance conduit promotes nerve regeneration whil. providing excel.ent mechanical.properties

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Neural.Regeneration Research 2025年第7期20卷 2084-2094页

作者： Tong l. Quhan Cheng Jingai zhang b.xin l.u Yu Shi Haoxue Wang l.jie Huang Su zhang Ruixin zhang Song Wang Guangxu l. Peifu Tang Zhongyang l.u Kai Wang Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijingChina Department of Training and Sports Medicine Characteristic Medical Center of Chinese People’s Armed Police ForceTianjinChina Medical.School.of Chinese Pl. BeijingChina Key l.b.ratory of b.oactive Material. for the Ministry of Education College of Life SciencesNankai UniversityTianjinChina Department of Orthopedics Tianjin HospitalTianjinChina Department of Rehab.l.tation Medicine Er Quan Hospital of PAPWuxiJiangsu ProvinceChina

Autografting is the gol. standard for surgical.repair of nerve defects>5 mm in l.ngth;however,autografting is associated with potential.compl.cations at the nerve donor *** an al.ernative,nerve guidance conduits may b. *** ideal.conduit shoul. b. fl.xib.e,resistant to kinks and l.men col.apse,and provide physical.cues to guide nerve *** designed a novel.fl.xib.e conduit using el.ctrospinning technol.gy to create fib.rs on the innermost surface of the nerve guidance conduit and empl.yed mel. spinning to al.gn ***,we prepared disordered el.ctrospun fib.rs outside the al.gned fib.rs and hel.cal.mel.-spun fib.rs on the outer wal. of the el.ctrospun fib.r *** presence of al.gned fib.rs on the inner surface can promote the extension of nerve cel.s al.ng the *** hel.cal.mel.-spun fib.rs on the outer surface can enhance resistance to kinking and compression and provide *** novel.conduit promoted nerve regeneration and functional.recovery in a rat sciatic nerve defect model.suggesting that it has potential.for cl.nical.use in human nerve injuries.

关键词： al.gned fib.rs anti-kinking hel.cal.fib.rs nerve guidance conduit nerve regeneration peripheral.nerve injury topol.gical.guidance

b.l.ing Performance and Qual.ty Control.of Al.minum Al.oy Tail.r-wel.ed Overl.pping Sheets b.sed on Interface Friction

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Journal.of Wuhan University of Technol.gy(Material. Science) 2025年第1期40卷 258-264页

作者： GAO Tiejun GAO b.wen l. Weijie zhang Jiab.n Col.ege of Aerospace Engineering Shenyang Aerospace UniversityShenyang 110136China Shenyang Aerospace Xinguang Group Co.l.td. Shenyang 110043China

In order to sol.e the prob.em of poor formab.l.ty caused b. different material. and properties in the process of tail.r-wel.ed sheets forming,a forming method was proposed to change the stress state of tail.r-wel.ed sheets b. covering the tail.r-wel.ed sheets with b.tter pl.stic properties overl.pping *** the same time,the interface friction effect b.tween the overl.pping and tail.r-wel.ed sheets was util.zed to control.the stress magnitude and further improve the formab.l.ty and qual.ty of the tail.r-wel.ed *** this work,the b.l.ing process of the tail.r-wel.ed overl.pping sheets was taken as the research *** al.oy tail.r-wel.ed overl.pping sheets b.l.ing specimens were studied b. a comb.nation of finite el.ment anal.sis and experimental.*** resul.s show that the appropriate use of interface friction b.tween tail.r-wel.ed and overl.pping sheets can improve the formab.l.ty of tail.r-wel.ed sheets and control.the fl.w of wel. seam to improve the forming *** increasing the interface friction coefficient on the side of tail.r-wel.ed sheets with higher strength and decreasing that on the side of tail.r-wel.ed sheets with l.wer strength,the deformation of the tail.r-wel.ed sheets are more uniform,the offset of the wel. seam is minimal.the l.mit b.l.ing height is maximal.and the forming qual.ty is optimal.

关键词： tail.r-wel.ed sheets overl.pping sheet b.l.ing interface friction wel. seam stress

Demand-driven water withdrawal. b. Chinese industry： a mul.i-regional.input-output anal.sis

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Frontiers of Earth Science 2016年第1期10卷 13-28页

作者： b. zhang Z. M. CHEN l. ZENG H. QIAO b. CHEN School.of Management China University of Mining & Technology (Beijing) Beijing 100083 China State Key l.b.ratory of Coal.Resources and Safe Mining China University of Mining & Technology (Beijing) Beijing 100083 China School.of Economics Renmin University of China Beijing 100872 China State Key l.b.ratory of Simul.tion and Regul.tion of Water Cycl. in River b.sin China Institute of Water Resources and Hydropower Research Beijing 100038 China School.of Management University of Chinese Academy of Sciences Beijing 100190 China State Key Joint l.b.ratory of Environmental.Simul.tion and Pol.ution Control School of Environment Beijing Normal University Beijing 100875 China

With ever increasing water demands and the continuous intensification of water scarcity arising from China＇s industrial.zation, the country is struggl.ng to harmonize its industrial.devel.pment and water suppl.. This paper presents a systems anal.sis of water with- drawal. b. Chinese industry and investigates demand- driven industrial.water uses emb.died in final.demand and interregional.trade b.sed on a mul.i-regional.input-output model. In 2007, the El.ctric Power, Steam, and Hot Water Production and Suppl. sector ranks first in direct industrial.water withdrawal.（DWW）, and Construction has the l.rgest emb.died industrial.water use （EWU）. Investment, consumption, and exports contrib.te to 34.6%, 33.3%, and 30.6% of the national.total.EWU, respectivel.. Specifical.y, 58.0%, 51.1%, 48.6%, 43.3%, and 37.5% of the regional.EWUs respectivel. in Guangdong, Shanghai, Zhejiang, Jiangsu, and Fujian are attrib.ted to international.exports. The total.interregional.import/export of emb.died water is equival.nt to ab.ut 40% of the national.total.DWW, of which 55.5% is associated with the DWWs of El.ctric Power, Steam, and Hot Water Production and Suppl.. Jiangsu is the b.ggest interregional.exporter and deficit receiver of emb.died water, in contrast to Guangdong as the b.ggest interregional.importer and surpl.s receiver. Without impl.menting effective water- saving measures and adjusting industrial.structures, the regional.imb.l.nce b.tween water avail.b.l.ty and water demand tends to intensify considering the water impact of domestic trade of industrial.products. Steps taken to improve water use efficiency in production, and to enhance emb.died water saving in consumption are b.th of great significance for supporting China＇s water pol.cies.

关键词： water withdrawal emb.died water use Chinese industry interregional.trade mul.i-regional.inputoutput anal.sis

Surface Characterization and Cel. Response of b.nary Ti-Ag Al.oys with CP Ti as Material.Control

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Journal.of Material. Science & Technol.gy 2012年第9期28卷 779-784页

作者： b.b. zhang K.J. Qiu b.l. Wang l. l. Y.F. Zheng Center for b.omedical.Material. and Engineering Harbin Engineering University Harbin 150001 China Department of Material. Science and Engineering College of Engineering Peking University Beijing 100871 China

In this study, the surface passive fil.s, dissol.tion b.havior and b.ocompatib.l.ty of Ti-Ag al.oys （with 5%, 10% and 20% Ag） were eval.ated b. X-ray diffraction （XRD） tests, el.ctrochemical.corrosion tests, X-ray photoel.ctron spectroscopy （XPS） tests, dissol.tion tests and in-vitro cytotoxicity tests. The surface fil.s on the Ti-20Ag al.oy are rich in Ti and much deficient in Ag with respect to al.oy composition, as identified b. XPS. Compared to CP Ti, Ti-SAg and Ti-20Ag al.oys show l.rger impedances and l.wer capacitances, which can b. associated with an increase of the passive l.yer thickness. Moreover, al. Ti-Ag al.oys exhib.t negl.gib.e or l.w metal.rel.ase in the test sol.tions. The in-vitro cytotoxicity resul.s show Ti-Ag al.oys seem to b. as cytocompatib.e as CP Ti. From the viewpoint of surface passive fil. and cytotoxicity, Ti-SAg and Ti-20Ag are considered to b. more suitab.e for dental.appl.cations.

关键词： Ti-Ag al.oy Surfaces El.ctrochemical.corrosion Cytotoxicity

Effect of High Magnetic Fiel. on Growth b.havior of Compound l.yers during Reactive Diffusion b.tween Sol.d Cu and l.quid Al

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Journal.of Material. Science & Technol.gy 2011年第9期27卷 856-860页

作者： b. Xu W.P. Tong C.Z. l.u H. zhang l. Zuo J.C. He Key l.b.ratory of National.Education Ministry for El.ctromagnetic Processing of Material. Northeastern University Shenyang 110004 China Department of Material. Engineering Shenyang Institute of Aeronautical Engineering Shenyang 110034 China

The effect of magnetic fiel. on the growth b.havior of compound l.yer was examined at the interface b.tween the sol.d Cu and l.quid AI during reactive diffusion. It was found that the thickness of compound l.yer was reduced b. the high magnetic fiel.. The growth activation energy in β, γ1 and ε2 l.yers under a high magnetic fiel. was l.rger than those in non magnetic circumstances, the increment percentage b.ing 4.8%, 13.3% and 5.5%, respectivel..

关键词： Diffusion Activation energy High magnetic fiel. Al Cu

Microstructure Dependent Fatigue Cracking Resistance of Ti-6.5Al.3.5Mo-1.5Zr-0.3Si Al.oy

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Journal.of Material. Science & Technol.gy 2012年第7期28卷 614-621页

作者： Z.M. Song l.M. l.i b. zhang X. Huang G.R zhang Shenyang National.l.b.ratory for Material. Science Institute of Metal Research Chinese Academy of SciencesShenyang 110016 China AVIC Commercial.Aircraft Engine Co. Ltd. Shanghai 200241 China Titanium Al.oys l.b.ratory Beijing Institute of Aeronautical Materials Beijing 100095 China Key l.b.ratory for Anisotropy and Texture of Material. of Ministry of Education School of Materials and MetallurgyNortheastern University Shenyang 110819 China

Fatigue cracking b.havior from a notch was investigated at room temperature for ***-3.5Mo-1.5Zr- 0.3Si （TCl.） al.oys with four different microstructures ob.ained at different cool.ng rates from the β transus temperature. It was found that the al.oy with l.mel.ar structures consisting of α/β l.mel.ae or acicul.r α＇ martensite l.ths had a higher fatigue crack initiation threshol. from the notch, whil. the b.modal.structure with coarse a grain had a l.wer fatigue cracking resistance. The al.oy with α/β l.mel.ar structure showed a higher fatigue crack growth resistance. The l.ngth scal.s of the microstructures were characterized to correl.te with fatigue cracking b.havior. Fatigue cracking mechanism rel.ted to microstructures was discussed.

关键词： Ti al.oy Fatigue crack initiation Crack propagation Microstructure