Surface Characterization and Cell Response of Binary Ti-Ag Alloys with CP Ti as Material Control

作     者：B.B. Zhang K.J. Qiu B.L. Wang L. Li Y.F. Zheng 

作者机构：Center for Biomedical Materials and Engineering Harbin Engineering University Harbin 150001 China Department of Materials Science and Engineering College of Engineering Peking University Beijing 100871 China 

出 版 物：《Journal of Materials Science & Technology》 (材料科学技术（英文版）)

年 卷 期：2012年第28卷第9期

页      面：779-784页

核心收录：

学科分类：082903[工学-林产化学加工工程] 08[工学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 0806[工学-冶金工程] 0817[工学-化学工程与技术] 0829[工学-林业工程] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 0802[工学-机械工程] 0702[理学-物理学] 0801[工学-力学（可授工学、理学学位）] 10[医学] 

基　　金：supported by the National Basic Research Program of China ("973 Program", Nos.2012CB619102 and 2012CB619100) the National High Technology Research and Development Program of China ("863 Program", Nos. 2011AA030101 and2011AA030103) the National Natural Science Foundation of China (Nos. 31170909 and 51041004) the Research Fund for the Doctoral Program of Higher Education (No. 20100001110011) the Fundamental Research Funds for the Central Universities (Nos. HEUCFZ1017and HEUCFR1020) the Natural Science Foundation of Heilongjiang Province, China (No. ZD201012) 

主　　题：Ti-Ag alloy Surfaces Electrochemical corrosion Cytotoxicity 

摘      要：In this study, the surface passive films, dissolution behavior and biocompatibility of Ti-Ag alloys （with 5%, 10% and 20% Ag） were evaluated by X-ray diffraction （XRD） tests, electrochemical corrosion tests, X-ray photoelectron spectroscopy （XPS） tests, dissolution tests and in-vitro cytotoxicity tests. The surface films on the Ti-20Ag alloy are rich in Ti and much deficient in Ag with respect to alloy composition, as identified by XPS. Compared to CP Ti, Ti-SAg and Ti-20Ag alloys show larger impedances and lower capacitances, which can be associated with an increase of the passive layer thickness. Moreover, all Ti-Ag alloys exhibit negligible or low metal release in the test solutions. The in-vitro cytotoxicity results show Ti-Ag alloys seem to be as cytocompatible as CP Ti. From the viewpoint of surface passive film and cytotoxicity, Ti-SAg and Ti-20Ag are considered to be more suitable for dental applications.