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Effects of land use change on hydrological cycle from forest to upland field in a catchment,Japan

Frontiers of Structural and Civil Engineering 2013年第4期7卷 456-465页

作者： Chuan ZHANG Keiji TAKASE Hiroki OUE nobuhiro EBISU Haofang YAN The United Graduate School of Agricultural Sciences Ehime UniversityEhime Pref 790-8577Japan Faculty of Bioresources and Environmental Sciences Ishikawa PrefecturalIshikawa 920-8580Japan Faculty of Agriculture Ehime UniversityEhime Pref 790-8577Japan

Understanding the effects of land use change on the hydrological cycle is very important for development of sustainable water resource in an upland field *** this study,soil and hydrological properties in an upland field catchment,which was reclaimed partially from a forest catchment,were compared with another forest *** soil properties of surface and subsurface layers were investigated in the two *** soil was compacted and waterholding capacity of soil in the upland field catchment became smaller after the reclamation from forest to upland field,which decreased infiltration rate and water storage in the soil *** found that peak discharge and direct runoff in the upland field catchment increased compared with the forest *** evapotranspiration from the upland field catchment tended to be lower due to the change in vegetation type and soil ***,a semi-distributed hydrological model was applied in the upland field catchment to understand the integrated effects of reclamation on the hydrological *** model parameters,which were determined using a nonlinear optimization technique—the Shuffled Complex Evolution method(SCE),were compared between the two *** Nash and Sutcliffe coefficient was used to evaluate the model *** simulated results indicated that evapotranspiration was decreased and change in discharge was more obvious in the surface *** considered that declined infiltration and water storage and increased peak discharge and direct runoff have a negative impact on water resources in the upland field *** study will provide information for forest managers in planning and making decisions for land and water resource management.

关键词： land-use change hydrological processes upland field catchment forest catchment semi-distributed hydrological model

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Voltammetric response of ferroceneboronic acid to diol and phenolic compounds as possible pollutants

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Journal of Environmental Sciences 2011年第6期23卷 1027-1032页

作者： Shigehiro Takahashi Naoyuki Abiko nobuhiro Haraguchi Hiroyuki Fujita Eriko Seki Tetsuya Ono Kentaro Yoshida Jun-ichi Anzai Graduate School of Pharmaceutical Sciences Tohoku UniversityAramakiAoba-kuSendai 980-8578Japan School of Pharmaceutical Sciences Ohu University31-1 MisumidoTomita-machiKoriyamaFukushima 963-8611Japan

A voltammetric determination of possible organic pollutants such as diol and phenolic compounds in water was studied using ferroceneboronic acid（FBA） as a redox-active marker.A cyclic voltammogram of FBA exhibited a pair of oxidation and reduction peaks at 230 and 170 mV at pH 7.0,respectively,while another pair of redox peaks was observed in the presence of diol or phenolic compounds *** results were rationalized based on the formation of boronate esters of FBA with the added *** changes in the redox peak currents were dependent on the concentration of the additives,suggesting a usefulness of FBA in the electrochemical determination of these compounds in water.

关键词： ferroceneboronic acid sugar phenolic compound cyclic voltammetry pollutants in water electrochemical determination

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Effect of high pressure torsion process on the microhardness,microstructure and tribological property of Ti6Al4V alloy

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Journal of Materials Science & Technology 2021年第35期94卷 183-195页

作者： Guanyu Deng Xing Zhao Lihong Su Peitang Wei Liang Zhang Lihua Zhan Yan Chong Hongtao Zhu nobuhiro Tsuji School of Mechanical MaterialsMechatronic and Biomedical EngineeringUniversity of WollongongNSW 2500Australia Department of Materials Science and Engineering Kyoto UniversityKyoto 606-8501Japan State Key Laboratory of High Performance Complex Manufacturing.Central South University Changsha 4W083China Stare Key Laboratory of Mechanical Transmissions Chongqing UniversityChongqing 400030China International Joint Laboratory for Light Alloys(MOE) College of Materials Science and EngineeringChongqing UniversityChongqing 400044China Department of Materials Science and Engineering University of California BerkeleyCA 94720United States Elements Strategy Initiative for Structural Materials(ESISM) Kyoto UniversityKyoto 606-8501Japan

In the present study,a fully lamellar Ti6Al4V alloy was severely deformed by high pressure torsion(HPT)process under a pressure of 7.5 GPa up to 10 *** results revealed that the microhardness of Ti6Al4V was increased remarkably by about~41%and saturated at about 432 Hv after the HPT process.A relatively uniform bulk nanostructured Ti6Al4V alloy with an average grain size of about52.7 nm was obtained eventually,and no obvious formation of metastableωphase was detected by XRD *** the first time,the tribological properties of the HPT processed Ti6Al4V alloy were investigated by a ball-on-disc test at room temperature under a dry *** was found that HPT process had a great influence on the friction and wear behaviors of Ti6Al4V *** increasing the number of HPT revolutions,both friction coefficient and specific wear rate were obviously decreased due to the reduction of abrasion and adhesion *** being deformed by 10 HPT revolutions,the friction coefficient was reduced from about 0.49 to 0.37,and the specific wear rate was reduced by about 48%.The observations in this study indicated that HPT processed Ti6Al4V alloys had good potential in structural applications owing to their greatly improved mechanical and tribological properties.

关键词： Severe plastic deformation High pressure torsion UFG microstructure Mechanical property Friction and wear Ti6Al4V alloy

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Liver cirrhosis in Japan:Future global trends in the era of progressive antiviral therapy

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Portal Hypertension & Cirrhosis 2022年第3期1卷 178-183页

作者： Hirayuki Enomoto Tomoyuki Takashima Takashi Nishimura nobuhiro Aizawa Naoto Ikeda Yukihisa Yuri Mamiko Okamoto Kohei Yoshihara Ryota Yoshioka Shoki Kawata Shogo Ota Ryota Nakano Hideyuki Shiomi Hiroko Iijima Department of Internal Medicine Division of Hepatobiliary and Pancreatic DiseaseHyogo Medical UniversityHyogoJapan

In Japan,viral hepatitis is the main cause of chronic liver diseases,including liver *** to the availability of highly effective antiviral drugs in combination with antihepatitis measures,Japan has become one of the most successful countries in the world with regard to hepatitis virus *** Japan,there are many elderly patients who have been infected with hepatitis C virus for a long time,and antihepatitis measures have been in place since the ***,the medical situation in Japan is expected to reflect the future situation in other countries where hepatitis countermeasures have been recently initiated and the infected population is *** nationwide survey clarified the changes in the etiologies of liver cirrhosis in *** viral hepatitis remains a major cause of liver cirrhosis in Japan,nonviral cirrhosis is suggested to increasingly contribute to the etiologies of liver cirrhosis,as opposed to viral hepatitis‐related liver *** changing etiology of liver cirrhosis in Japan may help to predict future global trends in chronic liver diseases.

关键词： antihepatitis measures antiviral drugs etiology liver cirrhosis viral hepatitis

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LiNA OperaScope^(TM) for microwave endometrial ablation for endometrial polyps with heavy menstrual bleeding: A case report

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World Journal of Clinical Cases 2023年第36期11卷 8557-8562页

作者： Kaoru Kakinuma Toshiyuki Kakinuma Kyouhei Ueyama Takumi Shinohara Rora Okamoto Kaoru Yanagida nobuhiro Takeshima Michitaka Ohwada Department of Obstetrics and Gynecology International University of Health and Welfare HospitalTochigi 329-2763NasushiobaraJapan

BACKGROUND The procedure for microwave endometrial ablation(MEA)follows established MEA practice guidelines but requires hysteroscopic observation of the uterine lumen before and after *** a luminal uterine lesion is recognized,its removal requires preoperative dilation of the cervix because the outer diameter of a conventional rigid hysteroscope is 8.7 ***,a fully disposable rigid hysteroscope(LiNA OperaScope^(TM))with a narrow diameter(4.4 mm)and forceps capable of extracting endometrial lesions has become *** SUMMARY Here,we report a case of heavy menstrual bleeding(HMB)complicated by endometrial polyps where MEA was performed after removing endometrial polyps using the LiNA OperaScope^(TM) device.A 48-year-old woman with three prior pregnancies and three deliveries was referred to our hospital for further examination and treatment after being diagnosed with HMB 2 years *** patient underwent MEA following endometrial polypectomy using LiNA OperaScope^(TM).After MEA,endometrial cauterization was again examined using the LiNA OperaScope^(TM),and the procedure was *** preoperative cervical dilation was *** patient’s clinical course was favorable,and she was discharged 3 h after *** month after surgery,menstruation resumed,and both HMB and dysmenorrhea improved markedly from 10 preoperatively to 1 postoperatively,as assessed subjectively using the visual analog *** patient’s postoperative course was uneventful with no *** LiNA OperaScope^(TM) can be a minimally invasive treatment for MEA of HMB with uterine lumen lesions.

关键词： Heavy menstrual bleeding Microwave endometrial ablation Endometrial polyp Hysteroscopy Minimally invasive surgery Dysmenorrhea Case report

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Rice-Specific Mitochondrial Iron-Regulated Gene （MIR） Plays an Important Role in Iron Homeostasis

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Molecular Plant 2009年第5期2卷 1059-1066页

作者： Yasuhiro Ishimaru Khurram Bashir Masaru Fujimoto Gynheung An Reiko Nakanishi Itai nobuhiro Tsutsumi Hiromi Nakanishi Naoko K Nishizawa Graduate School of Agricultural and Life Sciences The University of Tokyo 1-1-1 Yayoi Bunkyo-Ku Tokyo 113-8657 Japan Department of Life Sciences Pohang University of Science and Technology Pohang 790-784 Republic of Korea Research Institute for Bioresources and Biotechnology Ishikawa Prefectural University Ishikawa 921-8836 Japan

Mitochondria utilize iron （Fe）, but the proteins involved in mitochondrial Fe regulation are not characterized in plants. We cloned and characterized a mitochondrial iron-regulated （MIR） gene in rice involved in Fe homeostasis. MIR, when expressed in tobacco BY-2 cells, was localized to the mitochondria. MIR transcripts were greatly increased in response to Fe deficiency in roots and shoot tissue. MIR is not homologous to any known protein, as homologs were not found in the rice or Arabidopsis genome databases, or in the EST database for other organisms. Growth in the MIR T-DNA knockout rice mutant （mir） was significantly impaired compared to wild-type （WT） plants when grown under Fe-deficient or -sufficient conditions. Furthermore, mir plants accumulated more than twice the amount of Fe in shoot and root tissue compared to WT plants when grown under either Fe-sufficient or -deficient conditions. Despite the high accumulation of Fe in roots and shoots, mir plants triggered the expression of Fe-deficiency-inducible genes, indicating that mir may not be able to utilize Fe for physiological functions. These results clearly suggest that MIR is a rice-specific mitochondrial protein, recently evolved, and plays a significant role in Fe homeostasis.

关键词： Fe-deficiency-regulated gene Fe homeostasis mitochondria Oryza sativa.

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Current trends in three-dimensional visualization and real-time navigation as well as robot-assisted technologies in hepatobiliary surgery

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World Journal of Gastrointestinal Surgery 2021年第9期13卷 904-922页

作者： Yun Wang Di Cao Si-Lin Chen Yu-Mei Li Yun-Wen Zheng nobuhiro Ohkohchi Institute of Regenerative Medicine and Affiliated Hospital of Jiangsu UniversityJiangsu UniversityZhenjiang 212001Jiangsu ProvinceChina Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Faculty of MedicineUniversity of TsukubaTsukuba 305-8575IbarakiJapan Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine and School of Biotechnology and Heath SciencesWuyi UniversityJiangmen 529020Guangdong ProvinceChina School of Medicine Yokohama City UniversityYokohama 234-0006KanagawaJapan

With the continuous development of digital medicine,minimally invasive precision and safety have become the primary development trends in hepatobiliary *** to the specificity and complexity of hepatobiliary surgery,traditional preoperative imaging techniques such as computed tomography and magnetic resonance imaging cannot meet the need for identification of fine anatomical ***-based three-dimensional(3D)reconstruction,virtual simulation of surgery and 3D printing optimize the surgical plan through preoperative assessment,improving the controllability and safety of intraoperative operations,and in difficult-to-reach areas of the posterior and superior liver,assistive robots reproduce the surgeon’s natural movements with stable cameras,reducing natural *** navigation in abdominal surgery solves the problem of conventional surgery still relying on direct visual observation or preoperative image *** summarize and compare these recent trends in digital medical solutions for the future development and refinement of digital medicine in hepatobiliary surgery.

关键词： Hepatobiliary surgery Three-dimensional visualization Three-dimensional printing Electromagnetic tracking Real-time navigation Robot-assisted surgery

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Pancreatic neuroendocrine tumor and solid-pseudopapillary neoplasm: Key immunohistochemical profiles for differential diagnosis

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World Journal of Gastroenterology 2016年第38期22卷 8596-8604页

作者： Yusuke Ohara Tatsuya Oda Shinji Hashimoto Yoshimasa Akashi Ryoichi Miyamoto Tsuyoshi Enomoto Kaishi Satomi Yukio Morishita nobuhiro Ohkohchi Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Faculty of MedicineUniversity of Tsukuba Department of Diagnostic Pathology Faculty of MedicineUniversity of Tsukuba Diagnostic Pathology Division Tokyo Medical University Ibaraki Medical Center

AIM To reveal better diagnostic markers for differentiating neuroendocrine tumor(NET) from solid-pseudopapillary neoplasm(SPN), focusing primarily on immunohistochemical *** We reviewed 30 pancreatic surgical specimens of NET(24 cases) and SPN(6 cases). We carried out comprehensive immunohistochemical profiling using 9 markers: Synaptophysin, chromogranin A, pancytokeratin, E-cadherin, progesterone receptor,vimentin, α-1-antitrypsin, CD10, and β-*** E-cadherin staining in NETs, and nuclear labeling of β-catenin in SPNs were the most sensitive and specific markers. Dot-like staining of chromogranin A might indicate the possibility of SPNs rather than NETs. The other six markers were not useful because their expression overlapped widely between NETs and SPNs. Moreover, two cases that had been initially diagnosed as NETs on the basis of their morphological features, demonstrated SPN-like immunohistochemical profiles. Careful diagnosis is crucial as we actually found two confusing cases showing disagreement between the tumor morphology and immunohistochemical *** E-cadherin, chromogranin A, and β-catenin were the most useful markers which should be employed for differentiating between NET and SPN.

关键词： Neuroendocrine tumor Pancreas Solidpseudopapillary neoplasm Immunohistochemistry Diagnosis

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Prescription trends in children with pervasive developmental disorders:a claims data-based study in Japan

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世界儿科杂志:英文版 2016年第4期12卷 443-449页

作者： Michihiro Satoh Taku Obara Hidekazu Nishigori nobuhiro Ooba Yoshihiko Morikawa Mami Ishikuro Hirohito Metoki Masahiro Kikuya Nariyasu Mano Department of Pharmaceutical Sciences Tohoku University HospitalSendaiJapan Department of Preventive Medicine and Epidemiology Tohoku Medical Megabank OrganizationTohoku University2-1 Seiryo-choAoba-kuSendaiMiyagi 980-8575Japan Division of Molecular Epidemiology Tohoku University Graduate School of MedicineSendaiJapan Department of Obstetrics and Gynecology Tohoku University Graduate School of MedicineSendaiJapan School of Pharmacy Nihon UniversityChibaJapan Clinical Research Support Center Tokyo Metropolitan Children’s Medical CenterTokyoJapan Department of Community Medical Supports Tohoku Medical Megabank OrganizationTohoku UniversitySendaiJapan

Background:The only drug approved for pervasive developmental disorders(PDD)in Japan is *** psychotropic drugs are also prescribed for offlabel use in Japan,but details regarding their prescription and use are largely *** purpose of this study was to clarify the use of drug treatment in Japanese children with ***:Data were extracted from claims data from the Japan Medical Data Center for children younger than 18 years of age who were newly diagnosed with PDD(International Classification of Diseases version 10 codes:F84)from 2005 to 2010(total of 3276 patients as of 2010).The prescription rates were presented as the percentage of PDD patients who were prescribed each ***:Prior to 2010,the prescription rates for atypical antipsychotics,other antipsychotics,psychostimulants,all other central nervous system drugs,anticovnvulsants,non-barbiturates,and Parkinson’s disease/syndrome drugs significantly increased among the Anatomical Therapeutic Chemical classifications defined as the“nervous system”(trend P≤0.02).The prescription rate for risperidone consistently increased,reaching 6.9%in 2010(trend P<0.0001),the highest rate of the surveyed drugs among the *** prescription rate for aripiprazole also increased(trend P<0.0001),reaching 1.9%in *** prescription rate for pimozide showed no annual changes,with a low rate of 0.4%in ***:Compared with pimozide,the prescription rates for risperidone,aripiprazole and other psychotropic drugs have *** safety data for these drugs in Japanese children are sparse,there is a need for future safety evaluations of these drugs in Japanese children.

关键词： autism children pervasive developmental disorders prescription

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A Large Calcifying Cystic Odontogenic Tumor Occupying the Maxillary Sinus: A Case Report and Review of Literature

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Open Journal of Stomatology 2017年第5期7卷 291-298页

作者： Hiroshi Nakamura Shigehiro Tamaki nobuhiro Ueda nobuhiro Yamakawa Yuichiro Imai Tadaaki Kirita Department of Oral and Maxillofacial Surgery Nara Medical University Nara Japan Department of Oral Surgery Takai Hospital Tenri Japan Department of Oral Surgery Rakuwakai Otowa Hospital Kyoto Japan

Calcifying cystic odontogenic tumor (CCOT) is an uncommon benign cystic neoplasm of the jaw that develops from the odontogenic epithelium. It is clinically characterized as a painless—slow-growing tumor that affects the maxilla as well as the mandible, and generally occurs in young adults in the third or fourth decade of life. Herein, we present the case of a 16-year-old Japanese boy who showed a CCOT in the maxillary sinus. Panoramic radiography showed a unilocular lesion in the left maxillary sinus. Computed tomography showed an approximately 5-cm well-defined unilocular expansile lesion with multiple radiopaque calcific specks, arising from the left maxillary alveolar ridge. The lesion was surgically removed, under general anesthesia, and the patient was followed up for 3 years after the surgery, and there have not been any signs of recurrence.

关键词： Calcifying Cystic Odontogenic Tumor Maxillary Sinus Ghost Cells

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