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Zoological Research 2024年第1期45卷 79-94页

作者： Ya-Ling Zhu Lei-Lei Meng Jin-Hu Ma Xin Yuan shu-Wen Chen Xin-Rui Yi Xin-Yu Li Yi Wang yun-shu Tang Min Xue Mei-Zi Zhu Jin Peng Xue-Jin Lu Jian-Zhen Huang Zi-Chen Song Chong Wu Ke-Zhong Zheng Qing-Qing Dai Fan Huang Hao-shu Fang Department of Pathophysiology Anhui Medical UniversityHefeiAnhui 230032China Laboratory Animal Research Center School of Basic Medical SciencesAnhui Medical UniversityHefeiAnhui 230032China Department of Hepatobiliary Surgery First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230022China College of Animal Science and Technology Jiangxi Agricultural UniversityNanchangJiangxi 330045China

Non-alcoholic fatty liver disease(NAFLD)is associated with mutations in lipopolysaccharide-binding protein(LBP),but the underlying epigenetic mechanisms remain ***,LBP^(-/-)rats with NAFLD were established and used to conduct integrative targetingactive enhancer histone H3 lysine 27 acetylation(H3K27ac)chromatin immunoprecipitation coupled with high-throughput and transcriptomic sequencing analysis to explore the potential epigenetic pathomechanisms of active enhancers of NAFLD exacerbation upon LBP ***,LBP^(-/-)reduced the inflammatory response but markedly aggravated high-fat diet(HFD)-induced NAFLD in rats,with pronounced alterations in the histone acetylome and regulatory *** total,1128 differential enhancer-target genes significantly enriched in cholesterol and fatty acid metabolism were identified between wild-type(WT)and LBP^(-/-)NAFLD *** on integrative analysis,CCAAT/enhancer-binding proteinβ(C/EBPβ)was identified as a pivotal transcription factor(TF)and contributor to dysregulated histone acetylome H3K27ac,and the lipid metabolism gene SCD was identified as a downstream effector exacerbating *** study not only broadens our understanding of the essential role of LBP in the pathogenesis of NAFLD from an epigenetics perspective but also identifies key TF C/EBPβand functional gene SCD as potential regulators and therapeutic targets.

关键词： Non-alcoholic fatty liver disease C/EBPβ Lipopolysaccharide-binding protein H3K27ac Integrative analysis Enhancer

Preparation，Characterization and Catalytic Activity of Anionic Clay Pillared by GaW＿9Zn＿3

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Chemical Research in Chinese Universities 1995年第4期11卷 354-356页

作者： ZHAHG Ji-yu ZHANG shu-yun YU Xin-wu HU Chang-wen Liang Zhao-jun and WANG En-bo (Department of Chemistry,Northeast Normal University,Changchun,130024) NE NORMAL UNIV DEPT CHEMCHANGCHUN 130024PEOPLES R CHINA

Ｐｒｅｐａｒａｔｉｏｎ，ＣｈａｒａｃｔｅｒｉｚａｔｉｏｎａｎｄＣａｔａｌｙｔｉｃＡｃｔｉｖｉｔｙｏｆＡｎｉｏｎｉｃＣｌａｙＰｉｌｌａｒｅｄｂｙＧａＷ＿９Ｚｎ＿３ＺＨＡＨＧＪｉ－ｙｕ；ＺＨＡＮＧＳｈｕ－ｙｕｎ；ＹＵＸｉ... 详细信息

Ｐｒｅｐａｒａｔｉｏｎ，ＣｈａｒａｃｔｅｒｉｚａｔｉｏｎａｎｄＣａｔａｌｙｔｉｃＡｃｔｉｖｉｔｙｏｆＡｎｉｏｎｉｃＣｌａｙＰｉｌｌａｒｅｄｂｙＧａＷ＿９Ｚｎ＿３ＺＨＡＨＧＪｉ－ｙｕ；ＺＨＡＮＧＳｈｕ－ｙｕｎ；ＹＵＸｉｎ－ｗｕ；ＨＵＣｈａｎｇ－ｗｅｎＬ...

关键词： Anionic caly Heteropoiyanion Trisubstituted with transition metal Esterification activity

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中国基本医疗保险立法困局、症结及其出路

山西大学学报(哲学社会科学版) 2017年第3期40卷 142-150页

作者：孙淑云山西大学政治与公共管理学院

转型期中国,城乡基本医保制度正处于从"分割"走向"整合"的渐进性改革中,凸显中国基本医疗保险制度过渡型、未定型的时代局限性,不仅导致制定基本医保法律及其实施性法规一再陷入矛盾冲突之困局,还淹没和搁置了已经出台的《社会保险法》... 详细信息

转型期中国,城乡基本医保制度正处于从"分割"走向"整合"的渐进性改革中,凸显中国基本医疗保险制度过渡型、未定型的时代局限性,不仅导致制定基本医保法律及其实施性法规一再陷入矛盾冲突之困局,还淹没和搁置了已经出台的《社会保险法》。其症结在于,三项基本医保制度的核心构成要素及其制度结构,被渐进性从"分割"走向"整合"的城乡行政管理、城乡户籍管理、城乡公共财政、城乡医疗服务体系等体制性矛盾所掣肘和扭曲。破局之出路和对策是,以统一的、整合型基本医保实施性法规的制定为载体,从整体性、系统性体制创新视角,突破制约基本医保制度各个构成要素的体制性症结,全面整合和定型基本医保制度。

关键词：中国基本医疗保险立法转型期分割与整合体制机制创新

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社会保险理念下新型农村合作医疗制度的完善

山西大学学报(哲学社会科学版) 2012年第2期35卷 65-70页

作者：孙淑云山西大学法学院

新农合是政府主导、财政补助较高、农民缴费和保障水平都较低的、处于"试点"中的初级社会保险制度。将新农合提升为正规的缴费型社会保险制度,是《社会保险法》确定的发展方向。新农合制度完善和创新的决定性因素和首要任务,是贯彻社会... 详细信息

新农合是政府主导、财政补助较高、农民缴费和保障水平都较低的、处于"试点"中的初级社会保险制度。将新农合提升为正规的缴费型社会保险制度,是《社会保险法》确定的发展方向。新农合制度完善和创新的决定性因素和首要任务,是贯彻社会连带、互助共济、社会契约、社会共同责任等社会保险的理念,建立科学的筹资分担机制,并明确参保农民参与新农合管理监督的途径和方式。

关键词：社会保险理念新型农村合作医疗制度完善和创新

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试析20世纪非洲经济的两次转型

史学集刊 2015年第4期 14-23页

作者：舒运国上海师范大学非洲研究中心上海200234

非洲大陆在20世纪经历了两次经济转型。20世纪初,在西方资本主义扩张浪潮中,非洲沦为西方殖民地。殖民当局通过各种手段,包括经济手段与超经济的行政手段,强行推动非洲从传统经济向殖民地经济的转型。这次转型在二战前夕完成,非洲经济... 详细信息

非洲大陆在20世纪经历了两次经济转型。20世纪初,在西方资本主义扩张浪潮中,非洲沦为西方殖民地。殖民当局通过各种手段,包括经济手段与超经济的行政手段,强行推动非洲从传统经济向殖民地经济的转型。这次转型在二战前夕完成,非洲经济成为西方资本主义经济的附庸。1960年代非洲国家独立后,开始了第二次经济转型。为了消除殖民地经济遗毒,建立独立的民族经济,并且向现代化过渡,非洲国家先后经历了独立初期的仿效外部发展模式和1980年代的结构调整,但是效果并不理想。在总结历史经验的基础上,非洲国家在1990年代提出了"联合自强、自主发展"发展战略,并且取得了一定的进展。

关键词：非洲 20世纪经济转型

电感耦合等离子体质谱法测定食用植物油中的磷和硅

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分析化学 2017年第8期45卷 1222-1226页

作者：符靓施树云中南大学化学化工学院长江师范学院化学化工学院

建立了电感耦合等离子体串联质谱(ICP-MS/MS)准确测定食用植物油中的P和Si的方法。以HNO3+H2O2混合酸经密闭微波消解系统处理植物油样品,向碰撞反应池(CRC)中分别通入O2和H2,P与O2反应,利用O2质量转移,通过测定子离子31P16O+测定P,而Si... 详细信息

建立了电感耦合等离子体串联质谱(ICP-MS/MS)准确测定食用植物油中的P和Si的方法。以HNO3+H2O2混合酸经密闭微波消解系统处理植物油样品,向碰撞反应池(CRC)中分别通入O2和H2,P与O2反应,利用O2质量转移,通过测定子离子31P16O+测定P,而Si不与H2发生反应,利用H2原位质量反应消除质谱干扰,显著改善了分析结果的准确度。分别考察了不同O2和H2流速对31P16O+和28Si+信号强度和背景等效浓度(BEC)的影响,确定了最佳O2和H2流速。在优化的条件下,测得31P16O+和28Si+的检出限分别为0.043和0.66μg/L。采用本方法分析美国国家标准与技术研究院提供的标准参考物质润滑油(SRM 1848),结果表明,测定值与验证值无显著性差异。采用本方法分析来自中国不同产地的5种植物油(分别为油菜籽油、葵花籽油、花生油、玉米油和大豆油),结果表明,5种植物油中花生油的P含量最高,大豆油的Si含量最高。

关键词：食用植物油电感耦合等离子体串联质谱磷硅

Neolithic millet farmers contributed to the permanent settlement of the Tibetan Plateau by adopting barley agriculture

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National Science Review 2019年第5期6卷 1005-1013页

作者： Yu-Chun Li Jiao-Yang Tian Feng-Wen Liu Bin-Yu Yang Kang-shu-yun Gu Zia Ur Rahman Li-Qin Yang Fa-Hu Chen Guang-Hui Dong Qing-Peng Kong State Key Laboratory of Genetic Resources and Evolution/Key Laboratory of Healthy Aging Research of yunnan Province Kunming Institute of Zoology Chinese Academy of Sciences CAS Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences Key Laboratory of Western China’s Environmental Systems(Ministry of Education) Lanzhou University CAS Center for Excellence in Tibetan Plateau Earth Sciences and Key Laboratory of Alpine Ecology Institute of Tibetan Plateau Research(ITPCAS) Chinese Academy of Sciences

The permanent human settlement of the Tibetan Plateau(TP) has been suggested to have been facilitated by the introduction of barley agriculture ～3.6 kilo-years ago(ka).However, how barley agriculture spread onto the TP remains *** that the lower altitudes in the northeastern TP were occupied by millet cultivators from 5.2 ka, who also adopted barley farming ～4 ka, it is highly possible that it was millet farmers who brought barley agriculture onto the TP ～3.6 *** test this hypothesis, we analyzed mitochondrial DNA(mt DNA) from 8277 Tibetans and 58 514 individuals from surrounding populations,including 682 newly sequenced whole *** lines of evidence, together with radiocarbon dating of cereal remains at different elevations, supports the scenario that two haplogroups(M9a1a1c1b1a and A11a1a), which are common in contemporary Tibetans(20.9%) and were probably even more common(40–50%) in early Tibetans prior to historical immigrations to the TP, represent the genetic legacy of the Neolithic millet *** haplogroups originated in northern China between 10.0–6.0 ka and differentiated in the ancestors of modern Tibetans ～5.2–4.0 ka, matching the dispersal history of millet *** showing that substantial genetic components in contemporary Tibetans can trace their ancestry back to the Neolithic millet farmers, our study reveals that millet farmers adopted and brought barley agriculture to the TP ～3.6–3.3 ka, and made an important contribution to the Tibetan gene pool.

关键词： Tibetans millet farmers barley agriculture archaeology mitochondrial genomes

Axial chiral vortical effect in a sphere with finite size effect

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Chinese Physics C 2023年第3期47卷 187-205页

作者：杨淑芸方仁洪侯德富任海沧 Institute of Particle Physics and Key Laboratory of Quark and Lepton Physics(MOS) Central China Normal UniversityWuhan 430079China Key Laboratory of Particle Physics and Particle Irradiation(MOE) Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China Physics Department The Rockefeller University1230York AvenueNewYorkNY10021-6399

We investigate the axial vortical effect in a uniformly rotating sphere subject to finite *** use the MIT boundary condition to limit the boundary of the *** massless fermions inside the sphere,we obtain the exact axial vector current far from the boundary that matches the expression obtained in cylindrical coordinates in *** the spherical boundary,we find both the longitudinal and transverse(with respect to the rotation axis)components with magnitude depending on the colatitude *** massive fermions,we derive an expansion of the axial conductivity far from the boundary to all orders of mass,whose leading order term agrees with the mass correc-tion reported in *** also obtain the leading order mass correction on the boundary,which is linear and stronger than the quadratic dependence far from the *** qualitative implications on the phenomenology of heavy ion collisions are speculated.

关键词： heavy ion collisions quark-gluon plasmas axial-chiral-vortical-effect

Four new eremophilendiolides from Ligularia atroviolacea

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Chinese Chemical Letters 2007年第1期18卷 59-61页

作者： shu yun Shi Di Yao Wu Xun Gong Hua Peng Rong Ping Zhang Chang Xin Zhou Xiao Jiang Hao Zhong Jian Jia Joachim Stockigt Yu Zhao Department of Traditional Chinese Medicine and Natural Drug Research College of Pharmaceutical Sciences Zhejiang University Hangzhou 310031 China College of Pharmacy Kunming College of Medicine Kunming China Kunming Institute of Botany Chinese Academy of Sciences Kunming 650204 China Lehrstuhl fiir Pharmazeutische Biologie lnstitut fur Pharmazie Johannes-Gutenberg Universitiit Mainz D-55099 Mainz Germany

From Ligularia atroviolacea, four new eremophilendiolides, 81$-hydroxy-eremophil-3,7 （11）-dien-12,8α（14,6α）-diolide （1）, 8β-methoxy-eremophil-3,7（11）-dien-12,8α（14,6α）-diolide （2）, 8α-hydroxy-eremophil-3,7（11）-dien-12,8lβ（14,6α）-diolide （3） and eremophil-3,7（11）,8-trien-12,8 （14,6α）-diolide （4）, as well as a known diolide （5） were isolated. Their structures were elucidated on the basis of 1D and 2D NMR as well as ESI-MS spectral data.

关键词： Phytochemical examination Sesquiterpene Eremophilendiolide Ligularia atroviolacea