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Usefulness of the Japanese version of Rapid Dementia Screening Test for mild cognitive impairment in older patients with cardiovascular disease:a cross-sectional study

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Journal of Geriatric Cardiology 2021年第4期18卷 245-251页

作者： Takuji adachi yuki Tsunekawa Akihito Matsuoka Daisuke Tanimura Department of Integrated Health Sciences Nagoya University Graduate School of MedicineNagoyaJapan Department of Rehabilitation Nagoya Ekisaikai HospitalNagoyaJapan Department of Cardiology Nagoya Ekisaikai HospitalNagoyaJapan

BACKGROUND Cognitive decline is common among older patients with cardiovascular disease(CVD) and can decrease their self-management abilities. However, the instruments for identifying mild cognitive impairment(MCI) are not always feasible in clinical practice. Therefore, this study evaluated whether MCI could be detected using the Japanese version of the Rapid Dementia Screening Test(RDST-J), which is a simple screening tool for identifying cognitive *** This retrospective single-center study included patients who were ≥ 65 years old and hospitalized because of *** with a pre-hospitalization diagnosis of dementia were excluded. Each patient's cognitive function had been measured at discharge using the RDST-J and the Japanese version of the Montreal Cognitive Assessment(Mo CA-J), which is a standard tool for MCI screening. The correlation between the two scores was evaluated using Spearman's rank correlation coefficient. Receiver operating characteristic(ROC) analysis was also to evaluate whether the RDST-J could identify MCI, which was defined as a Mo CA-J score of ≤ 25 *** The study included 78 patients(mean age: 77.2 ± 8.9 years). The RDST-J and Mo CA-J scores were strongly correlated(r = 0.835, P < 0.001). The ROC analysis revealed that an RDST-J score of ≤ 9 points provided 75.4% sensitivity and 95.2% specificity for identifying MCI, with an area under the curve of 0.899(95% CI: 0.835-0.964). The same cut-off value was identified when excluding patients with a high probability of dementia(RDST-J score of ≤ 4 points).CONCLUSIONS The RDST-J may be a simple and effective tool for identifying MCI in older patients with CVD.

关键词： CVD MCI Usefulness of the Japanese version of Rapid Dementia Screening Test for mild cognitive impairment in older patients with cardiovascular disease:a cross-sectional study

Closed-Loop Control of an XYZ Micro-Stage and Designing of Mechanical Structure for Reduction in Motion Errors

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Nanomanufacturing and Metrology 2021年第1期4卷 53-66页

作者： Hiraku Matsukuma Keisuke adachi Takuma Sugawara yuki Shimizu Wei Gao Eiji Niwa Yoshihiro Sasaki Department of Finemechanics Graduate School of EngineeringTohoku UniversityMiyagiSendai 980-8579Japan Research Institute for Electromagnetic Materials 9-5-1 NaritaMiyagiTomiya 981-3341.Japan

This paper presents a compact XYZ micro-stage driven by an impact driving mechanism.A moving body is translationally actuated along the X-,Y-,and Z-axes in millimeter-scale range and with nanometer-scale ***-N thin-film strain sensors are integrated into the micro-stage for closed-loop ***-loop control is also carried *** motion errors in six degrees of freedom are also investigated for this *** is clarified by analysis of finite element method that rotational motion errors around the driving axis are caused by torques due to tensions from the elastic hinges of *** mechanical structure of XYZ micro-stage to cancel out the torque generated is proposed and the second prototype is *** the rotational motion error is successfully suppressed in the second prototype,a rotational motion error of more than 0.1°remains due to remaining torque and assembly error of the elastic ***,in order to reduce the rotational motion error,the prototype is designed in which the location of elastic hinges is *** designing a mechanical structure in which torque is suppressed,all rotational motion errors are successfully reduced to less than 0.05°in the prototype with single-layer hinges.

关键词： XYZ micro-stage Cr-N thin-film displacement sensor Closed-loop positioning Impact drive Friction drive

Pancreaticoduodenectomy after neoadjuvant chemotherapy for gastric cancer invading the pancreatic head:A case report

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World Journal of Gastroenterology 2021年第6期27卷 534-544页

作者： Masahiro Yura Kiminori Takano Kiyohiko adachi Asuka Hara Keita Hayashi yuki Tajima Yasushi Kaneko Yoichiro Ikoma Hiroto Fujisaki Akira Hirata Kumiko Hongo Kikuo Yo Kimiyasu Yoneyama Reiko Dehari Kazuo Koyanagi Motohito Nakagawa Department of Surgery Hiratsuka City HospitalHiratsuka 2540065KanagawaJapan Department of Surgical Pathology Hiratsuka City HospitalHiratsuka 2540065KanagawaJapan Department of Gastroenterological Surgery Tokai University School of MedicineIsehara 259193KanagawaJapan

BACKGROUND Pancreaticoduodenectomy(PD)for advanced gastric cancer is rarely performed because of the high morbidity and mortality rates and low survival ***,neoadjuvant chemotherapy for advanced gastric cancer has improved,and chemotherapy combined with trastuzumab may have a preoperative tumorreducing effect,especially for human epidermal growth factor receptor 2(HER2)-positive *** SUMMARY We report a case of successful radical resection with PD after neoadjuvant S-1 plus oxaliplatin(SOX)and trastuzumab in a patient(66-year-old male)with advanced gastric cancer invading the pancreatic *** esophagogastroduodenoscopy detected a type 3 advanced lesion located on the lower part of the stomach obstructing the pyloric *** tomography detected lymph node metastasis and tumor invasion to the pancreatic head without distant *** findings revealed adenocarcinoma and HER2 positivity(immunohistochemical score of 3+).We performed staging laparoscopy and confirmed no liver metastasis,no dissemination,negative lavage cytological findings,and immobility of the distal side of the stomach due to invasion to the *** gastrojejunostomy was performed at that *** course of SOX and three courses of SOX plus trastuzumab were *** computed tomography showed partial response;therefore,PD was performed after neoadjuvant chemotherapy,and pathological radical resection was *** We suggest that radical resection with PD after neoadjuvant chemotherapy plus trastuzumab is an option for locally advanced HER2-positive gastric cancer invading the pancreatic head in the absence of non-curative factors.

关键词： Pancreaticoduodenectomy Gastric cancer Neoadjuvant chemotherapy Trastuzumab Human epidermal growth factor receptor 2 Case report

Distal gastric tube resection with vascular preservation for gastric tube cancer:A case report and review of literature

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World Journal of Gastrointestinal Surgery 2020年第9期12卷 397-406页

作者： Masahiro Yura Kazuo Koyanagi Kiyohiko adachi Asuka Hara Keita Hayashi yuki Tajima Yasushi Kaneko Hiroto Fujisaki Akira Hirata Kiminori Takano Kumiko Hongo Kikuo Yo Kimiyasu Yoneyama Reiko Dehari Motohito Nakagawa Department of Surgery Hiratsuka City HospitalKanagawa 2540065Japan Department of Gastroenterological Surgery Tokai University School of MedicineIsehara 2591193Japan Department of Surgical Pathology Hiratsuka City HospitalKanagawa 2540065Japan

BACKGROUND Survival rates in patients with esophageal cancer undergoing esophagectomy have improved,but the prevalence of gastric tube cancer(GTC)has also *** resection of the gastric tube with lymph node dissection is considered a radical treatment,but GTC surgery is more invasive and involves a higher risk of severe complications or death,particularly in elderly *** SUMMARY We report an elderly patient with early GTC that had invaded the duodenum who was successfully treated with resection of the distal gastric tube and Roux-en-Y(R-Y)*** tumor was a type 0-IIc lesion with ulcer scars surrounding the pyloric *** submucosal resection was not indicated because the primary lesion was submucosally invasive,was undifferentiated type,surrounded the pyloric ring,and had invaded the *** of distal gastric tube with R-Y reconstruction was safely performed,with preservation of the right gastroepiploic artery(RGEA)and right gastric artery(RGA).CONCLUSION Distal resection of the gastric tube with preservation of the RGEA and RGA is a good treatment option for elderly patients with cT1bN0 GTC in the lower part of the gastric tube.

关键词： Gastric tube cancer Distal resection Preservation of right gastroepiploic artery and right gastric artery Elderly patients Duodenal invasion Case report Posterior mediastinal reconstruction