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Journal of Iron and Steel Research(International) 2012年第S1期19卷 596-599页

作者： Hideyuki HIRAZAWA Hiromichi AONO Takashi Naohara Tsunehiro MAEHARA yuji watanabe Department of Environmental Materials Engineering Niihama National College of TechnologyNiihama 792858 0 EhimeJapan Graduate School of Science and Engineering Ehime UniversityMatsuyama 790857 7Ehime Japan Department of Organ Regenerative Surgery Ehime UniversityToon 791029 5EhimeJapan

Mg_(1-X)Cu_XFe_2O_4 type spinel ferrite was prepared by solid reaction method in order to discuss the heat generation ability in AC magnetic *** cubic type ferrite structure was obtained for X=0-0.6 samples calcined at 1200℃,and the mixture phase of cubic and tetragonal structures were obtained for X=0.7,0.8 samples from XRD result. The highest lattice parameter and highest hysteresis loss value were also shown at X=0.6 sample,the crystal distortion was increased with increase the Cu^(2+)substitution in cubic type ferrite *** sized nano Mg_(0.4)Cu_(0.6)Fe_2O_4 powder was prepared by physical milling method using beads *** highest heat generation in the AC magnetic field was obtained for the 6 h milled samples using 0.1mm *** Cu^(2+)substitution for MgFe_2O_4 ferrite and the beads milling were very effective for the improvement of their heat generation ability in AC magnetic field.

关键词： heat generation ability AC magnetic field spinel ferrite beads milling

High-Frequency Induction Heating of Needle-Shaped Mg-Ferrite for Ablation Therapy of Human Cancer

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Journal of Iron and Steel Research(International) 2012年第S2期19卷 735-738页

作者： NAOHARA Takashi AONO Hiromichi MAEHARA Tsunehiro HIRAZAWA Hideyuki MATSUTOMO Shinya watanabe yuji Graduate School of Science and Engineering Ehime University Department of Environmental Materials Engineering Niihama National College of Technology Department of Electronic Control Engineering Niihama National College of Technology Department of Surgery Graduate School of MedicineEhime University

For application as a novel ablation therapy of human cancer,the heating property of a needle-shaped Mg-ferrite prepared by a sintering technique was studied in a high-frequency induction field at 370 *** inserted into cylindrical clay,the increase in temperature(Δ7)was 31.2℃ for the specimen with a 1.5 mm diameter,while the 1.0mm diameter specimen exhibited a ΔT value of 15.7℃ after the induction time of *** ΔT exhibited a high value of 57.9℃ during the simultaneous insertion of 3 1.5mm diameter *** the computer simulation images, the relatively lower magnetic flux density and concurrent neghgibly low current density were observed from the surface to the internal regions,being different from the behavior of a ferromagnetic Ni-rod with the same size.

关键词： high-frequency induction heating cancer therapy ablation treatment eddy current loss residual loss

Sigmoid colon endometriosis treated with laparoscopy-assisted sigmoidectomy:Significance of preoperative diagnosis

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World Journal of Gastroenterology 2007年第40期13卷 5400-5402页

作者： Motohira Yoshida yuji watanabe Atsushi Horiuchi yuji Yamamoto Hiroki Sugishita Kanji Kawachi Department of Organ Regenerative Surgery Ehime University Graduate School of MedicineShitsukawaToonEhime 791-0295Japan

我们在场外科手术前地正确地被诊断并且经历了最低限度地侵略的外科的有 S 字形的结肠子宫内膜增生的一个女病人。她与直肠的流血和便秘进入我们的医院。我们执行了几工作 ups。显示出的 S 字形的冒号狭窄由粘膜下层肿瘤引起了的结肠镜... 详细信息

我们在场外科手术前地正确地被诊断并且经历了最低限度地侵略的外科的有 S 字形的结肠子宫内膜增生的一个女病人。她与直肠的流血和便秘进入我们的医院。我们执行了几工作 ups。显示出的 S 字形的冒号狭窄由粘膜下层肿瘤引起了的结肠镜检查和内视镜的 ultrasonography，和磁性的回声成像揭示了在 T1 加权、 T2 加权的成像上显示信号 hy-pointensity 的一个 S 字形的冒号肿瘤。然而， colonoscopic 帮助 ultrasonography 的针针吸活组织检查不能指定肿瘤特征。从这些考试，当 S 字形的冒号子宫内膜增生和帮助 laparoscopy 的乙状结肠切除术被执行，损害被诊断。从 resected 标本的病理学的诊断与外科手术前的诊断相同，即，结肠的子宫内膜增生。因为肠的子宫内膜增生的鉴别诊断似乎困难，小心的外科手术前的诊断被要求包括最低限度地侵略的外科选择治疗。

关键词：子宫内膜异位手术诊断腹腔镜治疗

Huge mucinous borderline ovarian cystadenoma in a premenarchal girl

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Open Journal of Pediatrics 2012年第1期2卷 82-86页

作者： Atsushi Horiuchi Kazuhiro Kameoka Kouichi Sato yuji Yamamoto yuji watanabe Department of Surgery Division of Gastrointestinal Surgery and Surgical Oncology School of Medicine Ehime University Toon City Japan

Epithelial ovarian tumors are common in adult women, but rare in children. Especially mucinous ovarian cystadenoma is extremely rare, with only 16 cases in premenarchal girls reported to date. We present a case of 12-year-old premenarchal girl with symptoms of lower abdominal distension. CT showed a large multilocular tumor spreading throughout the entire abdominal cavity from the right upper quadrant to the pelvic cavity. The tumor was brought out little by little with aspiration of the fluid contents with a small incision. The tumor was found to originate from the left ovary, and oophorectomy was performed. The tumor measured 26 × 18 cm and weighed 5860 g. Histological diagnosis was mucinous ovarian cystadenoma with borderline malignancy. No evidence of recurrence had been seen as of 2 years postoperatively. In the review of premenarchal mucinous borderline ovarian cystadenoma, all cases were stage I and underwent salpingo-oophorectomy or oophorectomy. Those patients were alive without recurrence. Al-though mucinous borderline ovarian cystadenoma was characterized as malignancy, premenarchal cases showed favorable outcomes and salpingo-oohprectomy or oophorectomy appears appropriate.

关键词： Ovary Mucinous Cystadenoma Borderline Tumor Premenarchal

Evaluation of prognostic factors and scoring system in colonic perforation

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World Journal of Gastroenterology 2007年第23期13卷 3228-3231页

作者： Atsushi Horiuchi yuji watanabe Takashi Doi Kouichi Sato Syungo Yukumi Motohira Yoshida yuji Yamamoto Hiroki Sugishita Kanji Kawachi Department of Surgery 2 Ehime University School of Medicine

AIM: To study the significance of scoring systems assessing severity and prognostic factors in patients with colonic perforation. METHODS: A total of 26 patients (9 men, 17 women; mean age 72.7 ± 11.6 years) underwent emergency operation for colorectal perforation in our institution between 1993 and 2005. Several clinical factors were measured preoperatively and 24 h postoperatively. Acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ), Mannheim peritonitis index (MPI) and peritonitis index of Altona (PIA Ⅱ) scores were calculated preoperatively. RESULTS: Overall postoperative mortality rate was 23.1% (6 patients). Compared with survivors, non- survivors displayed low blood pressure, low serum protein and high serum creatinine preoperatively, and low blood pressure, low white blood cell count, low pH, low PaO2/FiO2, and high serum creatinine postoperatively. APACHE Ⅱ score was significantly lower in survivors than in non-survivors (10.4 ± 3.84 vs 19.3 ± 2.87, P = 0.00003). Non-survivors tended to display high MPI score and low PIA Ⅱ score, but no signif icant difference was identif ied. CONCLUSION: Pre- and postoperative blood pressure and serum creatinine level appear related to prognosis of colonic perforation. APACHE Ⅱ score is most associated with prognosis and scores ≥ 20 are associated with signif icantly increased mortality rate.

关键词：结肠穿孔刮伤系统预兆因子症状

用于FDG-PET和弥散加权MRI图像融合的最佳单色组合

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中华核医学与分子影像杂志 2018年第12期38卷 838-838页

作者：唐军(译) Ryotaro Kamei yuji watanabe Koji Sagiyama Takuro Isoda Osamu Togao Hiroshi Honda 上海交通大学医学院附属苏州九龙医院核医学科 215021 Department of Molecular Imaging and Diagnosis Kyushu University Graduate School of Medical Sciences FukuokaJapan

目的研究用于FDG-PET和弥散加权(DW)MRI图像融合的最佳单色组合,以利于显示两者各自的病灶。方法6种线性单色红、蓝、绿、青、品红和黄色分别用于显示FDG-PET和弥散加权成像(DWI)。使用光度计测量病灶颜色的亮度和色度,计算病灶颜色的... 详细信息

目的研究用于FDG-PET和弥散加权(DW)MRI图像融合的最佳单色组合,以利于显示两者各自的病灶。方法6种线性单色红、蓝、绿、青、品红和黄色分别用于显示FDG-PET和弥散加权成像(DWI)。使用光度计测量病灶颜色的亮度和色度,计算病灶颜色的视觉差异。通过比较PET、DWI和PET-DWI融合图像各自显示的病灶阳性部分的平均显著性得分来评价病灶的视觉显著性。采用单因素方差分析和Spearman秩相关进行统计分析。结果在12种可能的单色组合中,红/青、品红/绿和红/绿组合显示的病灶显著性得分最高。PET图像病灶和融合图像病灶阳性部分的总颜色差别与显著性得分相关(ρ=0.2933,P<0.005),而以上两者的亮度差异与病灶显示的显著性得分呈显著负相关。

关键词： FDG-PET 弥散加权MR成像图像融合色觉图像处理

Short-and long-term results of endoscopic ultrasoundguided transmural drainage for pancreatic pseudocysts and walled-off necrosis

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World Journal of Gastroenterology 2017年第39期23卷 7110-7118页

作者： Yuto watanabe Rintaro Mikata Shin Yasui Hiroshi Ohyama Harutoshi Sugiyama yuji Sakai Toshio Tsuyuguchi Naoya Kato Department of Gastroenterology Graduate School of Medicine Chiba University

AIM To evaluate the short-and long-term results of endoscopic ultrasound-guided transmural drainage(EUS-GTD) for pancreatic fluid collection(PFC) and identify the predictive factors of treatment outcome for walled-off necrosis(WON) managed by EUS-GTD *** We investigated 103 consecutive patients with PFC who underwent EUS-GTD between September 1999 and August 2015. Patients were divided into four groups as follows: WON(n = 40), pancreatic pseudocyst(PPC; n = 11), chronic pseudocyst(n = 33), and others(n = 19). We evaluated the short-and long-term outcomes of the treatment. In cases of WON, multiple logistic regression analyses were performed to identify the predictor variables associated with the treatment success. In addition, PFC recurrence was examined in patients followed up for more than 6 mo and internal stent removal after successful EUS-GTD was *** In this study, the total technical success rate was 96.1%. The treatment success rate of WON, PPC, chronic pseudocyst, and others was 57.5%, 90.9%, 91.0%, and 89.5%, respectively. Contrast-enhanced computed tomography using the multivariate logistic regression analysis revealed that the treatment success rate of WON was significantly lower in patients with more than 50% pancreatic parenchymal necrosis(OR = 17.0; 95%CI: 1.9-150.7; P = 0.011) and in patients with more than 150 mm of PFC(OR = 27.9; 95%CI: 3.4-227.7; P = 0.002).The recurrence of PFC in the long term was 13.3%(median observation time, 38.8 mo). Mean amylase level in the cavity was significantly higher in the recurrence group than in the no recurrence group(P = 0.02).CONCLUSION The reduction of WON by EUS-GTD alone was associated with the proportion of necrotic tissue and extent of the cavity. The amylase level in the cavity may be a predictive factor for recurrence of PFC.

关键词：内视镜的指导超声的 transmural 排水胰腺的液体收集修订亚特兰大分类围离开的坏死

Angle of covered self-expandable metallic stents after placement is a risk factor for recurrent biliary obstruction

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World Journal of Hepatology 2022年第5期14卷 992-1005页

作者： Kojiro Tanoue Hirotsugu Maruyama Yuki Ishikawa-Kakiya Yosuke Kinoshita Kappei Hayashi Masafumi Yamamura Masaki Ominami yuji Nadatani Shusei Fukunaga Koji Otani Shuhei Hosomi Fumio Tanaka Noriko Kamata Yasuaki Nagami Koichi Taira Toshio watanabe Yasuhiro Fujiwara Department of Gastroenterology Osaka City University Graduate School of MedicineOsaka 545-8585Japan

BACKGROUND Studies have shown that covered self-expandable metallic stents(CSEMS)with a low axial forces after placement can cause early recurrent biliary obstruction(RBO)due to precipitating sludge *** To ascertain whether the angle of CSEMS after placement is a risk factor for RBO in unresectable distal malignant biliary obstruction(MBO).METHODS Between January 2010 and March 2019,261 consecutive patients underwent selfexpandable metallic stent insertion by endoscopic retrograde cholangiopancreatography at our facility,and 87 patients were included in this *** evaluated the risk factors for RBO,including the angle of CSEMS after placement as the primary *** measured the obtuse angle of CSEMS after placement on an abdominal radiograph using the SYNAPSE PACS *** also evaluated technical and functional success,adverse events,time to RBO(TRBO),non-RBO rate,survival time,cause of RBO,and reintervention procedure as secondary *** We divided the patients into two cohorts based on the presence or absence of *** angle of CSEMS after placement(per 1°and per 10°)was evaluated using the multivariate Cox proportional hazard analysis,which was an independent risk factor for RBO in unresectable distal MBO[hazard ratio,0.97 and 0.71;95%confidence interval(CI):0.94-0.99 and 0.54-0.92;P=0.01 and 0.01,respectively].For early diagnosis of RBO,the cut-off value of the angle of CSEMS after placement using the receiver operating characteristic curve was 130°[sensitivity,50.0%;specificity 85.5%;area under the curve 0.70(95%CI:0.57-0.84)].TRBO in the<130°angle group was significantly shorter than that in the≥130°angle group(P<0.01).CONCLUSION This study suggests that the angle of the CSEMS after placement for unresectable distal MBO is a risk factor for *** novel results provide pertinent information for future stent management.

关键词： Covered self-expandable metallic stents Recurrent biliary obstruction Malignant biliary obstruction Endoscopic retrograde cholangiopancreatography Angle Axial force

En bloc pancreaticoduodenectomy and right hemicolectomy for locally advanced right-sided colon cancer

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World Journal of Gastrointestinal Oncology 2017年第9期9卷 372-378页

作者： yuji Kaneda Hiroshi Noda Yuhei Endo Nao Kakizawa Kosuke Ichida Fumiaki watanabe Takaharu Kato Yasuyuki Miyakura Koichi Suzuki Toshiki Rikiyama Department of Surgery Saitama Medical CenterJichi Medical UniversitySaitama 330-8503Japan

AIM To assess the usefulness of en bloc right hemicolectomy with pancreaticoduodenectomy(RHCPD) for locally advanced right-sided colon cancer(LARCC).METHODS We retrospectively reviewed the database of Saitama Medical Center, Jichi Medical University, between January 2009 and December 2016. During this time, 299 patients underwent radical right hemicolectomy for right-sided colon cancer. Among them, 5 underwent RHCPD for LARCC with tumor infiltration to adjacent organs. Preoperative computed tomography(CT) was routinely performed to evaluate local tumor infiltration into adjacent organs. During the operation, we evaluated the resectability and the amount of infiltration into the adjacent organs without dissecting the adherent organs from the cancer. When we confirmed that radical resection was feasible and could lead to R0 resection, we performed RHCPD. The clinical data were carefully reviewed, and the demographic variables, intraoperative data, and postoperative parameters were *** The median age of the 5 patients who underwent RHCPD for LARCC was 70 years. The tumors were located in the ascending colon(three patients) and transverse colon(two patients). Preoperative CT revealed infiltration of the tumor into the duodenum in all patients, the pancreas in four patients, the superior mesenteric vein(SMV) in two patients, and tumor thrombosis in the SMV in one patient. We performed RHCPD plus SMV resection in three patients. Major postoperative complications occurred in 3 patients(60%) as pancreatic fistula(grade B and grade C, according to International Study Group on Pancreatic Fistula Definition) and delayed gastric empty. None of the patients died during their hospital stay. A histological examination confirmed malignant infiltration into the duodenum and/or pancreas in 4 patients(80%), and no patients showed any malignant infiltration into the SMV. Two patients were histologically confirmed to have tumor thrombosis in the SMV. All of the tumors had c

关键词： Locally advanced right-sided colon cancer Right hemicolectomy Malignant infiltration Inflammatory adhesion Pancreaticoduodenectomy

Identification and Enumeration Method of Both Eukaryotic and Prokaryotic Microorganisms in Food Sample

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Food and Nutrition Sciences 2016年第5期7卷 345-354页

作者： Katsuji watanabe Naoto Horinishi Kunimasa Matsumoto yuji Sogabe Department of Life Environment and Materials Science Graduate School of Engineering Fukuoka Institute of Technology Fukuoka Japan Global Application Development Center Shimadzu Co. Kyoto Japan

The method to analyze both eukaryotic and prokaryotic microorganisms without preliminary microbial information of sample seemed to be useful not only for research and investigation of microorganisms but also for industry using microorganisms. In the present manuscript, preparation of a new DNA primers, new reference database for 18S rDNA for our newly developed method [1]- [3], and analyses of eukaryotic and prokaryotic microorganisms in fermentation products were presented. In komekouji, Aspergillus spp., was enumerated to be 46.5 × 106 MPN g-1, and Penicillium spp., was enumerated to be 1.5 × 106 MPN g-1. In dry yeast, Saccharomyces group, were enumerated to be 8600 × 106 MPN g-1. In komekouji-miso, no eukaryotic microorganism was detected, while the other Bacillus spp., was numerically dominant (21.5 × 106 MPN g-1) as prokaryotic microorganisms, followed by B. subtilis group (4.65 × 106 MPN g-1), and the other Firmicutes (3.7 × 106 MPN g-1). The komekouji-miso included lower number of Actinobacteria (0.15 × 106 MPN g-1), Burkhokderia sp. (1.5 × 106 MPN g-1), and the other α,β,γ-proteobacteria (0.12 × 106 MPN g-1). In sake-kasu, both prokaryote and eukaryote were not detected by the method. Present results indicated that using both universal primers for eukaryotic and prokaryotic microorganisms, each groups of prokaryotic and eukaryotic microorganisms were enumerated without any preliminary information nor setting up standard curve, which were required for real time PCR.

关键词： Eukaryotic Microorganisms Prokaryotic Microorganisms Multiple Enzyme Restriction Fragment Length Polymorphism Analysis the Most Probable Number Method Microchip Electrophoresis