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Journal of Energy Chemistry 2019年第5期28卷 78-84页

作者： Jin-Tao Ren yue-jun song Zhong-Yong Yuan National Institute for Advanced Materials School of Materials Science and EngineeringNankai UniversityTianjin 300350China Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)Nankai UniversityTianjin 300071China

Molybdenum-based electrocatalysts are promising candidates of platinum (Pt)-based materials in electrocatalyzing hydrogen evolution reaction (HER), due to their cost-efficient and resembled electronic properties. Reported herein is the preparation of molybdenum carbide nanoparticles uniformly decorated on nitrogen-modified carbons (Mo2C/NC) through the carbonization of Mo-based polymers under hydrogen atmosphere by using poly(p-phenylenediamine) and ammonium heptamolybdate polymer analogue as precursors. And the molybdenum nitride nanoparticles loaded on porous N-doped carbons (Mo2N/NC) are also fabricated by calcination the polymer precursors in nitrogen gas. The Mo2C/NC shows more excellent electrocatalytic activity than Mo2N/NC in 0.5 M H2SO4, together with robust long-term durability. The well-crystalline nanoparticles and the increased electron conductivity are the main characters responded for the high catalytic efficiency of the fabricated electrocatalysts. This easily fabrication procedure may provide a facile route to prepare non-noble metal carbide/nitride catalysts featuring wellengineered structural and textural peculiarities for realistic energy conversion system.

关键词： Molybdenum carbide Molybdenum nitride Nitrogen-doped carbon Hydrogen evolution reaction Electrocatalysis

Facile synthesis of Mo2C nanoparticles on N-doped carbon nanotubes with enhanced electrocatalytic activity for hydrogen evolution and oxygen reduction reactions

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Journal of Energy Chemistry 2019年第11期28卷 68-77页

作者： yue-jun song Jin-Tao Ren Gege Yuan Yali Yao Xinying Liu Zhong-Yong Yuan Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) National Institute for Advanced MaterialsSchool of Materials Science and EngineeringNankai UniversityTianjin 300350China Material and Process Synthesis College of ScienceEngineering and TechnologyUniversity of South AfricaJohannesburgSouth Africa

Developing low-cost and highly-efficient electrocatalysts for renewable energy conversion technologies has attracted even-increasing attention. Molybdenum carbide materials have recently emerged as a type of promising catalysts for electrocatalytic reactions due to the earth-abundance and Pt-resembled electrical properties. In this work, taking the advantage of the interaction between the basic groups of the Mo(VI)-melamine polymer and the acidic groups on the surface of the oxidized carbon nanotubes(CNTs), N-doped CNTs supported Mo2C nanoparticles(Mo2C/NCNT) are prepared, which exhibit outstanding electrocatalytic activity and durability for both the hydrogen evolution and oxygen reduction reactions. The impressive performance of Mo2C/NCNT can be attributed to the small size of Mo2C particles, the large exposure ratio of surface sites and the presence of N-doped CNTs. This work enlarges the multi-field applications of molybdenum carbide-base materials as promising non-precious metal electrocatalysts, which is of great significance for sustainable energy-related technologies.

关键词： N-doping Carbon nanotubes Molybdenum carbides Hydrogen evolution reaction Oxygen reduction reaction Electrocatalysis

Effect of cholinesterase inhibitor galanthamine on circulating tumor necrosis factor alpha in rats with lipopolysaccharideinduced peritonitis

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Chinese Medical Journal 2010年第13期123卷 1727-1730页

作者： LIU Zhi-hai MA yue-feng WU jun-song GAN Jian-xin XU Shao-wen JIANG Guan-yu Department of Emergency Medicine Second Affiliated Hospital Zhejiang University School of Medicine and Research Institute of Emergency Medicine Hangzhou Zhejiang 310009 China

Background The nervous system, through the vagus nerve and its neurotransmitter acetylcholine, can down-regulate the systemic inflammation in vivo, and recently, a role of brain cholinergic mechanisms in activating this cholinergic anti-inflammatory pathway has been indicated. Galanthamine is a cholinesterase inhibitor and one of the centrally acting cholinergic agents available in clinic. This study aimed to evaluate the effect of galanthamine on circulating tumor necrosis factor alpha （TNF-a） in rats with lipopolysaccharide-induced peritonitis and the possible role of the vagus nerve in the action of galanthamine. Methods Rat models of lipopolysaccharide-induced peritonitis and bilateral cervical vagotomy were produced. In the experiment 1, the rats were randomly divided into control group, peritonitis group, and peritonitis groups treated with three dosages of galanthamine. In the experiment 2, the rats were randomly divided into sham group, sham plus peritonitis group, sham plus peritonitis group treated with galanthamine, vagotomy plus peritonitis group, and vagotomy plus peritonitis group treated with galanthamine. The levels of plasma TNF-α were determined in every group. Results The level of circulating TNF-α was significantly increased in rats after intraperitoneal injection of endotoxin. Galanthamine treatment decreased the level of circulating TNF-α in rats with lipopolysaccharide-induced peritonitis, and there was significant difference compared with rats with lipopolysaccharide-induced peritonitis without treatment. The 3 mg/kg dosage of galanthamine had the most significant inhibition on circulating TNF-α level at all the three tested doses. Galanthamine obviously decreased the TNF-a level in rats with lipopolysaccharide-induced peritonitis with sham operation, but could not decrease the TNF-α level in rats with lipopolysaccharide-induced peritonitis with vagotomy. Conclusion Cholinesterase inhibitor galanthamine has an inhibitory effect on TNF-α relea

关键词： cholinesterase inhibitors galanthamine tumor necrosis factor alpha vagus nerve

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刚性桩复合地基在不同荷载下的桩土分担特性

天津大学学报（自然科学与工程技术版） 2003年第3期36卷 359-363页

作者：池跃君宋二祥陈肇元清华大学土木工程系北京100084

利用解析解答对刚性桩复合地基在竖向荷载下的工作特性进行了较深入的分析,着重讨论了桩土应力比及荷载分担比等随复合地基荷载、垫层厚度、垫层模量、桩长、桩间距、桩间土模量和桩端土抗力系数等因素变化的规律.计算结果表明,竖向荷... 详细信息

利用解析解答对刚性桩复合地基在竖向荷载下的工作特性进行了较深入的分析,着重讨论了桩土应力比及荷载分担比等随复合地基荷载、垫层厚度、垫层模量、桩长、桩间距、桩间土模量和桩端土抗力系数等因素变化的规律.计算结果表明,竖向荷载作用下,桩土应力比随复合地基荷载、垫层模量、桩长和桩间距的增加而增大,随垫层厚度和土体模量的增加而减小,同时也表明复合地基的设计参数有合理的取值范围.

关键词：刚性桩复合地基竖向荷载桩土应力比荷载分担比垫层厚度垫层模量桩长桩间距土体模量

毛泽东思想利益观的历史进程、核心内容和未来进路

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湖南第一师范学院学报 2020年第3期20卷 16-21页

作者：岳松君山东大学马克思主义学院山东济南250100

以毛泽东同志为主要代表的中国共产党人高度重视利益问题,在总结我国革命、建设中分析、解决利益问题的正反两方面历史经验的基础上不断形成和发展了毛泽东思想利益观。从历史进程看,毛泽东思想利益观在土地革命战争时期初步形成,在抗... 详细信息

以毛泽东同志为主要代表的中国共产党人高度重视利益问题,在总结我国革命、建设中分析、解决利益问题的正反两方面历史经验的基础上不断形成和发展了毛泽东思想利益观。从历史进程看,毛泽东思想利益观在土地革命战争时期初步形成,在抗日战争时期基本成熟,在解放战争时期和新中国成立以后继续发展。从核心内容看,毛泽东思想利益观基本立场是以人民为中心,基本观点是小利益服从大利益,基本方法是统筹兼顾、适当安排。从未来进路看,新的利益关系和利益问题要求我们在新时代继续坚持、运用和发展毛泽东思想利益观。

关键词：利益观利益毛泽东思想

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali song Luojia Wu Wei Wan Xiuqin Rao yue Lin Gen Wei jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

论中国特色社会主义制度应对重大疫情的制度优势

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泰山学院学报 2020年第3期42卷 115-119页

作者：岳松君山东大学马克思主义学院山东济南250100

随着我国抗击新型冠状病毒肺炎疫情取得阶段性成果和突破性进展,中国特色社会主义制度在应对重大疫情方面的制度优势在这场疫情中得到充分彰显,集中体现在以下几个方面:党的领导制度体系是核心制度优势、人民当家作主制度体系是首要制... 详细信息

随着我国抗击新型冠状病毒肺炎疫情取得阶段性成果和突破性进展,中国特色社会主义制度在应对重大疫情方面的制度优势在这场疫情中得到充分彰显,集中体现在以下几个方面:党的领导制度体系是核心制度优势、人民当家作主制度体系是首要制度优势、社会主义基本经济制度是基本制度优势、中国特色社会主义法治体系和行政体制是关键制度优势。对此,既要进一步坚定中国特色社会主义制度自信,又要针对疫情中暴露出的短板和不足,进一步充分发挥中国特色社会主义制度优势、推进国家治理体系和治理能力现代化。

关键词：中国特色社会主义制度重大疫情制度优势

Targets capture by distributed active swarms via bio-inspired reinforcement learning

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 210-221页

作者： Kun Xu yue Li jun Sun Shuyuan Du Xinpeng Di Yuguang Yang Bo Li Institute of Biomechanics and Medical Engineering Applied Mechanics Laboratory Department of Engineering MechanicsTsinghua University Institute of Nuclear and New Energy Technology Tsinghua University Shanghai Aerospace Control Technology Institute Shanghai Key Laboratory of Aerospace Intelligent Control Technology College of Automation Engineering Nanjing University of Aeronautics and Astronautics

Natural swarms arranged from cells to herds are usually decentralized but display intriguing collective intelligence in coordinating individuals across large scales to efficiently achieve their common goals. Learning from nature may provide new strategies for controlling collective dynamics of synthetic swarms to accomplish specific functions. Here, we present a bioinspired computational framework that steers distributed active swarms to collectively capture and merge targets via reinforcement learning. We exploit collective milling structures of natural herds to cage the targets, and adopt a switching control policy inspired by sperms' chiral dynamics to optimize the trajectories of individuals, through which the active swarms can selforganize to enclose single or multiple distant targets in a dynamical, adaptive and scalable manner. There exists a critical swarm size, beyond which the excessive competition between agents would generate large mechanical forces, leading to capture instability but enabling the transition from short-distance to long-distance merging capture of multiple targets. This work provides physical insights into distributed active swarms and could offer a multilevel, decentralized strategy toward controlling swarm robotics in wide applications such as bio-medical devices, machine immunity, and target clearance.

关键词： swarm intelligence robotics multi-tasks artificial intelligence bionics

经验公式法预测试验区最小混相压力适应性研究

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数学的实践与认识 2017年第18期47卷 285-289页

作者：赵跃军宋考平范广娟东北石油大学石油工程学院黑龙江大庆163318 东北石油大学地球科学学院黑龙江大庆163318

二氧化碳混相驱已经成为许多油田和学者研究的目标,实际数据表明混相驱比非混相驱能够获得更高的采收率,但不是所有油田区块都能全面实现混相驱,其中最小混相压力是形成混相驱关键因素之一.主要通过经验公式法对试验区原油与二氧化碳的... 详细信息

二氧化碳混相驱已经成为许多油田和学者研究的目标,实际数据表明混相驱比非混相驱能够获得更高的采收率,但不是所有油田区块都能全面实现混相驱,其中最小混相压力是形成混相驱关键因素之一.主要通过经验公式法对试验区原油与二氧化碳的最小混相压力进行预测,并通过现场实际测定的结果对各经验公式法预测的结果进行对比和分析,研究结果表明:The Petroleum Recovery Institutel关联式法(PRII)的预测结果误差最小,相对误差为1.09%,可作为试验区油田其他区块最小混相压力预测的经验公式.研究对与试验区具有相似特征区块最小混相压力的预测具有一定的指导意义.

关键词：最小混相压力二氧化碳混相驱经验公式法

Photothermal probiotics delivery of photodynamic agents for enhanced immunogenic cell death within hypoxia center of solid tumors

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Nano Research 2025年第1期18卷 642-652页

作者： Wen Luo Shiyu Du Yateng Jiang Bangshun He jun Tang Jingjing Yang Yujun song Jiangsu Key Laboratory of Artificial Functional Materials State Key Laboratory of Analytical Chemistry for Life ScienceNational Laboratory of Solid State MicrostructuresCollege of Engineering and Applied SciencesNanjing UniversityNanjing 210023China Department of Laboratory Medicine Nanjing First HospitalNanjing Medical UniversityNanjing 210006China Department of Anesthesiology Jinling HospitalMedical School of Nanjing UniversityNanjing 210000China Department of Biochemistry and Molecular Biology School of Medicine&Holistic Integrative MedicineJiangsu Collaborative Innovation Center of Chinese Medicinal Resources IndustrializationNanjing University of Chinese MedicineNanjing 210023China

Resulting from harsh hypoxic environmental conditions,central cells in the core of solid tumors are usually more aggressive and malignant with a less stable ***,therapeutic agents with improved penetration for the activation of immunity in tumor centers exhibit promising potential in ***,polydopamine-coated Escherichia coli Nissle 1917(EcN)bearing chlorin e6(Ce6)-loaded and polyethyleneimine(PEI)-coated hollow manganese dioxide(shorted as EP-ChP)are applied for enhanced immunotherapy in deep *** accumulation in tumor center through hypoxia targeting,manganese dioxide is degradated under the tumor microenvironment with released Ce6 and thus generates reactive oxygen species(ROS)upon 660 nm laser irradiation,which can further lower thermalresistance of cancer cells via HSP90α*** to that,heating induced by polydopamine upon 808 nm laser irradiation can achieve effective tumor *** upon dual laser induces enhanced immunogenic cell death,while bacterial infections in tumor tissues also trigger innate *** bacteria-based approach provides enhanced antitumor immune responses in deep tumors with great potential in the reshaping of immunosuppression tumor microenvironment.

关键词： bacteria phototherapies immunotherapy hypoxia targeting tumor penetration