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Chinese Medical Journal 2021年第4期134卷 472-474页

作者： Xue-Mei Wei Wen-Bo Yang Xiu-Xiu Su An-Di Zhang Wei Jin yue-Hua Fang Department of Cardiology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China lnstitute of Cardiovascular Disease Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

Heart failure(HF)is a worldwide problem due to the substantial morbidity and mortality of patients with cardiovascular diseases.Recently,the PARADIGM-HF trial(the Prospective comparison of angiotensin receptor-neprilysin inhibitor[ARNI]with angiotensin-converting enzyme inhibitor[ACEI]to Determine Impact on Global Mortality and morbidity in Heart Failure trial)showed that ischemic heart disease is the most common etiology of HF,which accounts for 60%of HF with reduced ejection fraction(HFrEF).

关键词： patients mortality severity

Development and Field Application of Phosphogypsum-Based Soil Subgrade Stabilizers

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Journal of Renewable Materials 2022年第8期10卷 2247-2261页

作者： Hongfei yue Aiguo fang Sudong hua Zenghuan Gu Yu Jia Cheng Yang College of Materials Science and Engineering Nanjing Tech UniversityNanjing211800China China Construction Installaction Engineering Co. Ltd.Nanjing210023China Jiangsu Subote New Material Co. Ltd.Nanjing211103China Sinoma Construction Co. Ltd.Suzhou215300China

A phosphogypsum-based subgrade stabilizer(PBSS)was formulated using industrial by-product phosphogypsum(PG),mixed with slag and calcium-silicon-rich active material(GSR).The active powder(AP)was used to modify PBSS,and PBSS-AP was obtained.PBSS and PBSS-AP were each mixed with 10%silty soil,and cement and lime(CAL:5%lime+2%cement)were used as the traditional material for comparative experiments.Samples were cured under standard conditions,and tested for unconfined compressive strength(UCS),water stability,volume expansion,and leachate,to explore the stabilization effect of the three solidified materials on silty soil.The results showed that the comprehensive performance of sility soil mixed with 12%PBSS-AP was the best.The CaO,SiO_(2)and Al_(2)O_(3)provided by PG,Slag and GSR will react with water to form a stable C-S-H gel,which is conducive to stabilizing the soil.Field application results showed that the compaction exceeded 95%,the deflection was 144.9 mm,and UCS was 2.5 MPa after 28 days.These findings indicated that PBSS-AP is an effective stabilizer for subgrade soils.

关键词： Phosphogypsum solidified material unconfined compressive strength water stability volume expansion leachate

The Immune Responses Induced by Licensed Flavivirus Vaccines against Zika Virus

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Biomedical and Environmental Sciences 2022年第8期35卷 750-754页

作者： WANG Ling LIU Jing Jing fang En yue LI Ming LIU Ming Lei LI Yu hua State Key Laboratory of Biotherapy and Cancer Center West China HospitalSichuan Universityand Collaborative Innovation Center for BiotherapyChengdu 610041SichuanChina National Institutes for Food and Drug Control Beijing 102629China

Zika virus(ZIKV) is a mosquito-borne virus of the Spondweni group that belongs to the Flaviviridae family and genus Flavivirus. Microcephaly(small head size, decreased brain size, and poor neurocognitive development) was linked to ZIKV infection in Brazil in 2015. Outbreaks and indications of transmission have spread quickly over the Americas, Africa, and other parts of the globe.Over 80 nations and territories have documented symptoms of Zika infection spread by mosquitoes,including microcephaly and Guillain-Barre syndrome(GBS).

关键词： infection Immune belongs

Atmospheric Corrosion of Q235 Carbon Steel and Q450 Weathering Steel in Turpan,China

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Journal of Iron and Steel Research(International) 2016年第10期23卷 1061-1070页

作者： Qiang YU Chao-fang DONG yue-Hua Fang Kui XIAO Chun-yun GUO Gang HE Xiao-gang LI Corrosion and Protection Center Key Laboratory for Corrosion and Protection University of Science and Technology Beijing Beijing 100083 China Xinjiang Turpan Natural Environmental Test Research Center Turpan 838200 Xinjiang China

Q235carbon steel and Q450 weathering steel were exposed to the hot and dry environment of Turpan,China for three years.The corrosion rates of both steels were calculated and compared.The morphologies of the rust layer products were observed by optical microscopy and scanning electron microscopy.Analyses of the rust layers were performed by X-ray photoelectron spectroscopy,X-ray powder diffraction,and Raman spectroscopy,and analysis results indicate that the compositions of rust are main iron rich oxide such as FeOOH,Fe_3O_4,and Fe_2O_3.The iron oxide layer content proportion was calculated through a semi-quantitative algorithm.The resistance elements（Cr,Ni,and Cu）enhanced the resistance properties of the Q450 weathering steel matrix.Moreover,the resistance elements increased the proportion of goethite crystals in the corroded rust layer.

关键词： atmospheric corrosion Q235 carbon steel Q450 weathering steel rust layer

Siderochelins with anti-mycobacterial activity from Amycolatopsis sp. LZ149

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Chinese Journal of Natural Medicines 2015年第1期13卷 69-72页

作者： LU Chun-hua YE fang-Wen SHEN yue-Mao Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Shandong University School of Life Sciences Xiamen University

Three new compounds, namely siderochelins D(2), E(3), and F(4), together with one known siderochelin A(1), were isolated from Amycolatopsis sp. LZ149 and elucidated by spectroscopic analyses including1D- and 2D-NMR an... 详细信息

关键词：传统医药药理学网络中国药物发现生物制药生物医学生物系统

Multi-scale traffic vehicle detection based on faster R-CNN with NAS optimization and feature enrichment

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Defence Technology 2021年第4期17卷 1542-1554页

作者： Ji-qing Luo Hu-sheng fang Fa-ming Shao yue Zhong Xia hua Department of Mechanical Engineering College of Field Engineering Army Engineering University of PLA

It well known that vehicle detection is an important component of the field of object detection.However,the environment of vehicle detection is particularly sophisticated in practical processes.It is comparatively difficult to detect vehicles of various scales in traffic scene images,because the vehicles partially obscured by green belts,roadblocks or other vehicles,as well as influence of some low illumination weather.In this paper,we present a model based on Faster R-CNN with NAS optimization and feature enrichment to realize the effective detection of multi-scale vehicle targets in traffic scenes.First,we proposed a Retinex-based image adaptive correction algorithm(RIAC) to enhance the traffic images in the dataset to reduce the influence of shadow and illumination,and improve the image quality.Second,in order to improve the feature expression of the backbone network,we conducted Neural Architecture Search(NAS) on the backbone network used for feature extraction of Faster R-CNN to generate the optimal cross-layer connection to extract multi-layer features more effectively.Third,we used the object Feature Enrichment that combines the multi-layer feature information and the context information of the last layer after cross-layer connection to enrich the information of vehicle targets,and improve the robustness of the model for challenging targets such as small scale and severe occlusion.In the implementation of the model,K-means clustering algorithm was used to select the suitable anchor size for our dataset to improve the convergence speed of the model.Our model has been trained and tested on the UN-DETRAC dataset,and the obtained results indicate that our method has art-of-state detection performance.

关键词： Neural architecture search Feature enrichment Faster R-CNN Retinex-based image adaptive correction algorithm K-means UN-DETRAC

Collaborative Efforts of Families, Schools, Health Care Providers, and the Government to Control Childhood Obesity in China

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Biomedical and Environmental Sciences 2021年第6期34卷 439-442页

作者： YANG Zhen Yu ZHANG Qian fang Hong Yun DING Xin yue ZHAO Wen hua National Institute for Nutrition and Health Chinese Center for Disease Control and PreventionBeijing 100050China

INTRODUCTION Globally,childhood obesity has gradually become prevalent in recent decades.According to estimations by United Nations International Children's Emergency Fund(UNICEF),the World Health Organization(WHO),and the World Bank,the global prevalence of being overweight for children under 5 years rose from 4.9%in 2000 to 5.6%in 2019[1].The Institute for Health Metrics and Evaluation(IHME)estimated that,between 1980 and 2015,the worldwide proportion of obesity increased from 3.9%to 7.2%and 3.7%to 6.4%in boys and girls aged 2-4 years,respectively121.Meanwhile,the Non-Communicable Diseases Risk Factor Collaboration reported that the global prevalence of obesity rose from 0.9%to 7.8%and 0.7%to 5.6%in boys and girls aged 5-19 years,respectively,between 1975 and 2016[3].Globally,the total number of overweight and obese individuals reached 40 and 340 million in children under 5 years and aged 5-19 years,respectively,in 2016.

关键词： UNICEF obesity prevalence

Patient-specific ventricular puncture trajectory plane and puncture trajectory: a novel method of frontal ventricular puncture

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Chinese Medical Journal 2021年第19期134卷 2359-2361页

作者： Chen-Yu Ding Jun-Yu Lin yue Chen yue Pang Xiao-Yong Chen Wen-hua fang fang-Yu Wang Yuang-Xiang Lin De-Zhi Kang Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian 350001China Fujian Provincial Key Laboratory of Precision Medicine for Cancer FuzhouFujian 350001China Department of Clinical Medicine Fujian Medical UniversityFuzhouFujian 350001China

Ventricular puncture is a common neurosurgical procedure,which is usually performed freehand using body surface anatomic landmarks as targeting references.[1,2]However,it is reported that the failure rate of freehand lateral ventricle puncture could be as high as 43%in traumatic brain injury cases if body surface anatomic landmarks are used as targeting references,[3]and the occurrence of hemorrhages associated with ventricular puncture could reach 16.2%.[4]Classic puncture sites,such as Kocher point,are helpful in improving the success rate of ventricular puncture.However,it is still risky to perform freehand puncture with classic puncture sites.Several causes could lead to this issue,including the following:(1)Individual patients have different conditions;a puncture approach suitable for all patients might not be possible.(2)Selection of puncture approach is largely dependent on the judgment of the surgeon,because the puncture approach does not usually fall on the coronal,sagittal,or axial images of the regular computed tomography(CT)scan;surgeons need to use spatial imagination based on CT images to design the ventricular puncture trajectory(VPT),which could lead to errors.(3)In freehand puncture,directional deviations could occur easily without the guidance of a frame as a fixed space reference to the puncture path.

关键词： puncture ventricular plane

Effects of hot compression deformation temperature on the microstructure and properties of Al–Zr–La alloys

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International Journal of Minerals,Metallurgy and Materials 2018年第2期25卷 236-243页

作者： Xian-hua yue Chun-fang Liu Hui-hua Liu Su-fen Xiao Zheng-hua Tang Tian Tang College of Materials Science and Engineering Sichuan University TBEA Deyang Cable Stock Co. Ltd.

The main goal of this study is to investigate the microstructure and electrical properties of Al–Zr–La alloys under different hot compression deformation temperatures. In particular, a Gleeble 3500 thermal simulator was used to carry out multi-pass hot compression tests. For five-pass hot compression deformation, the last-pass deformation temperatures were 240, 260, 300, 340, 380, and 420°C, respectively, where the first-pass deformation temperature was 460°C. The experimental results indicated that increasing the hot compression deformation temperature with each pass resulted in improved electrical conductivity of the alloy. Consequently, the flow stress was reduced after deformation of the samples subjected to the same number of passes. In addition, the dislocation density gradually decreased and the grain size increased after hot compression deformation. Furthermore, the dynamic recrystallization behavior was effectively suppressed during the hot compression process because spherical Al;Zr precipitates pinned the dislocation movement effectively and prevented grain boundary sliding.

关键词： microstructure Al–Zr–La alloys hot compression deformation dislocation

Effects of Hyperbaric Exposure on Hematology and Cecal Microbiota in Rats

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Biomedical and Environmental Sciences 2022年第6期35卷 538-542页

作者： ZHANG Chun Hong DONG Shu yue LI Dan LIU Jun MAO Wei Chang fang Yi Qun ZHANG Tie hua Navy Special Medical Center The Second Military Medical UniversityShanghai 200433China College of Food Science and Engineering Jilin UniversityChangchun 130062JilinChina

The diving operation has a direct bearing on the health of divers due to its particularity,and such effects are mainly related to hyperbaric exposure(HBE)[1],including exposure to high pressure,high oxygen environment... 详细信息

关键词： exposure operation decompression