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Mixed serous-neuroendocrine neoplasm of the pancreas: A case report and review of the literature

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World Journal of Clinical Cases 2019年第23期7卷 4119-4129页

作者： yue-mei Xu Zhi-Wen Li Hong-Yan Wu Xiang-Shan Fan Qi Sun Department of Pathology Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School

BACKGROUND Pancreatic mixed serous-neuroendocrine neoplasms(MSNNs)are mixed tumors containing two components with different pathologies,namely,pancreatic serous cystic neoplasm(PSCN)and pancreatic neuroendocrine tumor(PanNET).For MSNNs,diffuse PSCN involving the whole pancreas is extremely rare,with only eight previous case *** SUMMARY A 45-year-old Chinese woman,with a free previous medical history and no obvious symptoms,was found to have a pancreatic neoplasm and admitted to our hospital for further diagnosis in March *** palpation revealed a painless,mobile mass in the epigastrium,and no abnormalities were observed in an examination of the nervous system and ocular system.A computed tomography scan showed multiple cystic lesions involving the whole pancreas ranging in diameter from 0.4 to 2 cm and also revealed an enhanced mass,2.2 cm in diameter,in the head of the ***,multiple cysts were found in the kidneys bilaterally,and the right lobe of the liver contained a small cyst.A Whipple operation with total pancreatectomy and splenectomy was performed.A diagnosis of pancreatic MSNN was established,consisting of diffuse serous microcystic cystadenoma with a concomitant grade 2 *** note,the patient had no personal or family history of Von Hippel-Lindau syndrome or other *** We report the first case of MSNN with a diffuse PSCN component involving the entire pancreas in a Chinese *** is important to be aware of its relationship with VHL syndrome,and close clinical follow-up is recommended.

关键词： Mixed serous-neuroendocrine neoplasm Pancreatic serous cystic neoplasm Pancreatic neuroendocrine tumor Von Hippel-Lindau syndrome Case report

An efficient synthesis of 1,5-benzodiazepine derivatives catalyzed by boric acid

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Chinese Chemical Letters 2009年第8期20卷 905-908页

作者： Xin Zhou mei yue Zhang Shu Tao Gao Jing Jun Ma Chun Wang Chao Liu Hebei Key Laboratory of Bioinorganic Chemistry College of Sciences Agricultural University of Hebei Baoding 071001 China

1,5-Benzodiazepine derivatives have been synthesized by the condensation of o-phenylenediamines and ketones in the presence of boric acid as catalyst under mild conditions. This method is simple, environmentally benign and high yielding. ？2009 Chun Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： 1,5-Benzodiazepincs o-Phenylenediamines Boric acid Synthesis

孤独症儿童父母连带污名对亲子关系的影响:心理弹性的中介作用与家庭嘈杂度的调节作用

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中国健康心理学杂志 2024年第1期32卷 13-19页

作者：梅越高兴慧李鹏赵德虎王琳琳云南师范大学教育学部昆明650500 江苏省南通市通州区特殊教育学校

目的:考察连带污名对亲子关系的影响,探讨心理弹性的中介作用以及家庭嘈杂度的调节机制。方法:采用连带污名量表、亲子关系中文版量表、心理弹性中文版量表、CHAOS中文版量表,对890名孤独症儿童父母进行调查。结果:1连带污名与家庭嘈杂... 详细信息

目的:考察连带污名对亲子关系的影响,探讨心理弹性的中介作用以及家庭嘈杂度的调节机制。方法:采用连带污名量表、亲子关系中文版量表、心理弹性中文版量表、CHAOS中文版量表,对890名孤独症儿童父母进行调查。结果:1连带污名与家庭嘈杂度呈显著正相关(r=0.339,P<0.001),与心理弹性呈显著负相关(r=-0.200,P<0.001),与亲子关系呈显著负相关(r=-0.273,P<0.001);2孤独症儿童父母的连带污名可显著负向预测亲子关系(β=-0.12,P<0.001);③孤独症儿童父母的心理弹性在连带污名与亲子关系之间起部分中介作用;④家庭嘈杂度调节了孤独症儿童父母连带污名对亲子关系的直接效应,具体而言,在低水平的家庭嘈杂度下,连带污名对亲子关系的影响作用更为明显。结论:孤独症儿童父母连带污名对亲子关系存在显著负向影响,增强心理弹性和降低家庭嘈杂度是减轻该负向影响的重要路径。

关键词：连带污名亲子关系心理弹性家庭嘈杂度孤独症儿童父母

Effects of Mg Addition on Inclusions Formation and Resultant Solidification Structure Changes of Ti-stabilized Ultra-pure Ferritic Stainless Steel

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Journal of Iron and Steel Research International 2014年第6期21卷 583-588页

作者： Ying-tie XU Zhao-ping CHEN Mao-tao GONG Da SHU yue-mei TIAN Xiang-qian YUAN Research Institute Baoshan Iron and Steel Co.Ltd. State Key Laboratory of Metal Matrix Composite Shanghai Jiao Tong University

The effects of Mg addition on the formation of nonmetallic inclusions and solidification structure of Ti-sta- bilized ultra-pure ferritie stainless steels were investigated by experimentally casting ingots with different composi tions. Thermodynamic analyses on the formation of complex inclusions after adding Mg into steels were carried out combined with the scanning electron microscopy energy dispersive spectrometry （SEM EDS） analysis. And the EDS analysis showed that in steel samples with Mg addition, a new spinel crystal phase combined with AI2O3- TiOx formed. It was also found that after Mg addition, the proportions of equiaxed grain zone of 409L, 4003, 439 and 443NT steels increased from 10.2%, 21.8%, 13.4% and 18.6% to 84.3%, 92.3%, 91.1% and 100.0%, respec tively. Since the planar disregistry between spinel and TiN is 5. 1%0, spinel could promote the precipitation of TiN and increase the number density of TiN inclusions in steel melts. The mechanism of solidification structure refinement after adding Mg into steels supposed that the complex inclusions of spinel and TiN in high number density enhanced columnar-to-equiaxed transition, since the planer disregistry between δ phase and spinel is 1.4 %.

关键词： ferritic stainless steel Mg additionl inclusion TiN solidification structurel disregistry

Health care worker occupational experiences during the COVID-19 outbreak:A cross-sectional study

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World Journal of Clinical Cases 2022年第16期10卷 5275-5286页

作者： Xiao-Fang Li Xuan-Lin Zhou Sheng-Xiu Zhao yue-mei Li Shi-Qin Pan Department of Nursing Qinghai Provincial People’s HospitalXining 810007Qinghai ProvinceChina Department of Neurosurgery Qinghai Provincial People’s HospitalXining 810007Qinghai ProvinceChina

BACKGROUND Health care workers treating coronavirus disease 2019(COVID-19)patients experience burnout and stress due to overwork and poor working *** To investigate the work experiences of frontline health care workers in Wuhan city and Qinghai province,China,during the COVID-19 *** In this cross-sectional descriptive study,a self-reported questionnaire was designed to evaluate work experiences of medical staff throughout the course of the COVID-19 pandemic.A total of 178 health care workers responded to the questionnaire between February 19 and 29,*** questionnaire dimensional score confirmed dimensional *** Of all dimensions evaluated by this questionnaire,the occupational value dimension had the highest mean score of 2.61(0.59),followed by the support/security dimension score of 2.30(0.74).Occupational protection scored lowest at 1.44(0.75),followed by work environment at 1.97(0.81).The social relationships dimension had an intermediate score of 2.06(0.80).Significant differences in working conditions were observed across hospital departments,with the fever ward scoring *** scores also differed significantly across workplaces;the fever outpatient department scored lowest(P<0.01).This phenomenon was likely due to the fact that work in the fever outpatient department,where many patients present to hospital,necessitates constant contact with a large number of individuals with insufficient provision of resources(such as protective equipment and social support).Medical workers in the fever outpatient department were burdened with a fear of COVID-19 infection and a lower sense of professional value as compared to workers in other hospital *** staff in Wuhan worked longer hours(P<0.01)as compared to *** mean support/security dimension score was higher for tertiary hospital as compared to secondary hospital medical staff as well as for Wuhan area as compared to Qinghai region staff(P<0.01).S

关键词： Novel coronavirus COVID-19 Health care worker Occupational exposure Personal protective equipment

Detecting bulk and edge exceptional points in non-Hermitian systems through generalized Petermann factors

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Frontiers of physics 2024年第2期19卷 169-177页

作者： yue-Yu Zou Yao Zhou Li-mei Chen Peng Ye School of Physics State Key Laboratory of Optoelectronic Materials and Technologiesand Guangdong Provincial Key Laboratory of Magnetoelectric Physics and DevicesSun Yat-sen UniversityGuangzhou 510275China

Non-orthogonality in non-Hermitian quantum systems gives rise to tremendous exotic quantum phenomena,which can be fundamentally traced back to *** this paper,we introduce an interesting quantity(denoted asη)as a new variant of the Petermann factor to directly and efficiently measure non-unitarity and the associated non-Hermitian *** tuning the model parameters of underlying non-Hermitian systems,we find that the discontinuity of bothηand its first-order derivative(denoted as■η)pronouncedly captures rich physics that is fundamentally caused by *** concretely,in the 1D non-Hermitian topological systems,two mutually orthogonal edge states that are respectively localized on two boundaries become non-orthogonal in the vicinity of discontinuity ofηas a function of the model parameter,which is dubbed"edge state transition".Through theoretical analysis,we identify that the appearance of edge state transition indicates the existence of exceptional points(EPs)in topological edge *** the discontinuity of■η,we investigate a two-level non-Hermitian model and establish a connection between the points of discontinuity of■ηand EPs of bulk *** studying this connection in more general lattice models,we find that some models have discontinuity of■η,implying the existence of EPs in bulk states.

关键词： non-Hermitian Su−Schrieffer−Heeger(SSH)model exceptional point

围手术期血液保护措施对老年全髋关节置换术患者快速康复的影响

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中国现代药物应用 2024年第11期18卷 52-55页

作者：李就文陈月媚陈昌达陈木林李婉琴广东省东莞市东部中心医院输血科 523573 广东省东莞市东部中心医院手术室 523573 广东省东莞市东部中心医院检验科 523573 广东省东莞市大朗医院输血科 523777

目的探讨围手术期血液保护措施对老年全髋关节置换术患者快速康复的影响。方法选取择期行老年全髋关节置换术的患者120例为研究对象,随机分为常护组和自体血回输(ABT)+控制性降压(CH)组,各60例。常护组术中常规处理,ABT+CH组采用术中AB... 详细信息

目的探讨围手术期血液保护措施对老年全髋关节置换术患者快速康复的影响。方法选取择期行老年全髋关节置换术的患者120例为研究对象,随机分为常护组和自体血回输(ABT)+控制性降压(CH)组,各60例。常护组术中常规处理,ABT+CH组采用术中ABT联合CH处理。比较两组血细胞相关指标[血红蛋白(Hb)、红细胞比容(Hct)、血小板计数(PLT)],炎症反应指标[肿瘤坏死因子-α(TNF-α)、白介素-1β(IL-1β)、白介素-6(IL-6)、白介素-8(IL-8)、β-淀粉样蛋白S-100(S-100β蛋白)、神经元特异性烯醇化酶(NSE)],简易智力状态检查量表(MMSE)评分,Harris髋关节功能评分,康复相关时间指标。结果ABT+CH组术后7 d的Hb(122.25±7.02)g/L、Hct(37.25±7.63)%、PLT(3.72±0.96)×10^(11)/L显著高于常护组的(105.56±11.36)g/L、(31.25±6.89)%、(2.53±1.13)×10^(11)/L(P<0.05)。ABT+CH组术毕、术后1 d和术后7 d的TNF-α、IL-1β、IL-6、IL-8、S-100β蛋白、NSE水平均显著低于常护组(P<0.05)。ABT+CH组术后1 d及术后7 d的MMSE评分分别为(24.13±3.56)、(25.01±4.86)分,显著高于常护组的(22.03±4.02)、(22.81±2.76)分(P<0.05)。ABT+CH组术后1个月和3个月Harris髋关节功能评分分别为(85.26±7.12)、(90.25±8.17)分,显著高于常护组的(76.39±9.17)、(82.25±7.56)分(P<0.05)。ABT+CH组术后下床活动时间(3.36±1.25)d、患肢负重时间(6.25±1.14)d、住院时间(9.25±1.68)d均显著短于常护组的(5.18±1.75)、(7.89±1.35)、(12.03±2.16)d(P<0.05)。结论ABT联合CH是一种可靠的围手术期血液保护措施,可提升患者术后康复速度,应用效果可靠。

关键词：围手术期血液保护措施老年全髋关节置换术快速康复认知功能

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课程思政融入超声诊断学教学的探索与实践

中国继续医学教育 2024年第3期16卷 169-172页

作者：岳梅袁惠彭娟牛锦东李玉婷陈熙昆明医科大学第一附属医院超声科云南昆明650032

立德树人的成效是检验学校一切工作的根本标准,课程思政是落实立德树人要求的关键一招。把课程思政要求融入超声诊断学教学中,有利于实现传道授业相融合,提高学生基本素质,促进一流学科建设,构建大思政教育格局。基于超声诊断学课程思... 详细信息

立德树人的成效是检验学校一切工作的根本标准,课程思政是落实立德树人要求的关键一招。把课程思政要求融入超声诊断学教学中,有利于实现传道授业相融合,提高学生基本素质,促进一流学科建设,构建大思政教育格局。基于超声诊断学课程思政要求实施现状,可通过明确超声诊断学课程思政目标体系、构建超声诊断学准备+互动+巩固三步式教学模式、融合开展超声诊断学理论和实践教学、建立超声诊断学多元化考核评价体系、拓宽授课教师课程思政能力提升路径等系列措施,确保课程思政有机融入医学生培养过程中。

关键词：立德树人课程思政超声诊断学医学生存在问题实践路径

Two successful neonatal extracorporeal membrane oxygenation treatment for severe heart failure after cardiac surgery

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Chinese Medical Journal 2009年第21期122卷 2672-2674页

作者： TAN Lin-hua DU Li-zhong HE Xiao-jun SUN mei-yue ZHANG Ze-wei LIN Ru Department of Surgical Intensive Care Unit Children's Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310003 China Department of Cardiothoracic Surgery Children's Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310003 China

Extracorporeal membrane oxygenation （ECMO） can play an important role by providing short-term circulatory support to enable myocardial recovery in patients with life-threatening heart failure. Currently, over 4000 children who received ECMO for cardiac support have been reported to the Extracorporeal Life Support Registry, with the majority1 of patients placed on ECMO following cardiac surgery. It has been recently reported that the overall survival rate of approximately 40% in children requiring ECMO after repair of congenital heart lesions.1-3 The risk of mortality was significantly increased in boys, patients younger than 1 month old,

关键词： extracorporeal membrane oxygenation newborn heart failure