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Effects of PKCa antisense RNA on human breast cancer cell proliferation and expression of cyclinD1 and CDK4

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Chinese Science Bulletin 1999年第12期44卷 1110-1114页

作者： SANG Jianli wang YongchaoLaboratory of Cell Biology , department of Biology, Beijing normal university, Beijing 100875 , {4. Laboratory of Cell Biology Department of Biology Beijing Normal University Beijing China

The role of PKCα in human breast cancer cell proliferation and expression of cyclinD1 and CDK4.has been investigated using inhibition of PKCα expression by its antisense RNA. When PKCα expression was inhibited the rate of cell proliferation decreased apparently and the levels of cyclinD1 and CDK4.mRNA were lower than the control. The results showed that PKCα, a key member of signal transduction system, played an important role in human breast cancer cell proliferation and had a close relationship with expression of cyclinD1 and CDK4.which control start of cell cycle.

关键词： breast cancer PKCα cell proliferation cyclinD1 CDK4.

Non-isothermal decomposition kinetics and lifetime of Tb2(0-MBA)6(PHEN)2

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Rare Metals 2003年第3期22卷 155-159页

作者： ZHANGJianjun BAIJihai wangRuifen wangShuping LIJibiao ExperimentalCenter NormalUniversityShijiazhuang050016China departmentofComputer HebeiNormalCollegeofScienceandTechnologyChangli066600China departmentofChemistry HebeiNormalUniversityShijiazhuang050091China

The thermal decomposition of Tb_2(O-MBA)_6(PHEN)_2 (O-MBA: o-methylbenzoate;PHEN: 1,10-phenanthroline) and its kinetics were studied under the non-isothermal condition bythermogravimetry-derivative thermogravimetry (TG-DTG) techniques. Kinetic parameters were obtainedfrom analysis of TG-DTG curves by the Achar method and the Madhusudanan-Krishnan-Ninan (MKN) *** most probable mechanism function was suggested by comparing the kinetic parameters. The kineticequation for the first stage can be expressed as dα/dt = Aexp(-E/RT)·3(1 - α)^(2/3). Thelifetime equation at mass loss of 10% was deduced as lnτ= -28.74.9 + 19797.795/T by isothermalthermogravimetric analysis.

关键词： thermochimica non-isothermal kinetics TG-DTG terbium complex O-methylbenzoate 1,10-phenanthroline

Constraints on smoothness parameter and dark energy using observational H(z) data

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Research in Astronomy and Astrophysics 2011年第2期11卷 125-136页

作者： Hao-Ran Yu1,Tian Lan1,Hao-Yi Wan2,Tong-Jie Zhang1,3 and Bao-Quan wang4.1 department of Astronomy,Beijing normal university,Beijing 100875,{4. 2 Business Office,Beijing Planetarium,Beijing 10004.,{4. 3 Center for High Energy Physics,Peking university,Beijing 100871,{4. 4.department of Physics,Dezhou university,Dezhou 253023,{4. department of Astronomy Beijing Normal University Beijing 100875 China Business Office Beijing Planetarium Beijing 100044 China Center for High Energy Physics Peking University Beijing 100871 China department of Physics Dezhou University Dezhou 253023 China

With large-scale homogeneity,the universe is locally inhomogeneous,clustering into stars,galaxies and larger *** property is described by the smoothness parameter α which is defined as the proportion of matter in the form of intergalactic *** we consider the inhomogeneities over a small scale,there should be modifications of the cosmological distances compared to a homogenous *** and Roeder developed a second-order ordinary differential equation（D-R equation） that describes the angular diameter distance-redshift relation for inhomogeneous cosmological ***,we may obtain the D-R equation for observational H（z） data（OHD）.The density-parameter ΩM,the state of dark energy ω,and the smoothness-parameter α are constrained by a set of OHD in a spatially flat XCDM universe as well as a spatially flat XCDM *** using a χ2 minimization method,we get α = 0.81＋0.19-0.20 and ΩM = 0.32＋0.12-0.06 at the 1σ confidence *** we assume a Gaussian prior of ΩM = 0.26 ± 0.1,we get α = 0.93＋0.07-0.19 and ΩM = 0.31＋*** the XCDM model,α is constrained to α≥ 0.80 but ω is weakly constrained around-1,where ω describes the equation of state of the dark energy（pX = ωρX）.We conclude that OHD constrains the smoothness parameter more effectively than the data of SNe Ia and compact radio sources.

关键词： cosmology -- dark energy -- cosmological parameters

Cross-shore suspended sediment flux in the salt marsh pioneer zone of Chongming eastern beach in the Chang- jiang Estuary in china

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Acta Oceanologica Sinica 2010年第6期29卷 62-72页

作者： wang Chu YAO Dongjing HE Baogen ZHOU Naisheng XU Shiyuan department of Geography Shanghai Normal University Shanghai 200234 China department of Geography College of Resource and Environmental Science East China Normal University Shanghai 200062 China

Between April 2002 and April 2003,in situ measurements of water depth,current velocity and suspended sediment content were carried out in edge region of east Chongming salt marsh and neighboring bald flat in the Changjiang （Yangtze） Estuary under different weather ***-shore suspended sediment flux was calculated and *** results show that under calm weather conditions,the current velocity process in bald field and salt marsh area varied differently during semidiurnal tidal *** to current velocity asymmetry,mean SSC during flood tide phase was 1.8 times higher than that of ebb tide *** a result,net onshore sediment flux controlled cross-shore suspended sediment transport process and salt marsh pioneer zone was generally *** was significant positive correlation between total sediment flux and quartic power of maximum water *** indicates that tidal ranges dominate suspended sediment transport and sedimentation process in the salt marsh pioneer zone under the calm weather *** sedimentation rate on the adjacent mudflat was higher than the salt marsh,which induced stable accreting of salt marsh towards the *** wind events enhanced SSC and current velocity during the semidiurnal *** the remarkable onshore net sediment flux could occur on the high marsh and mudflat close to the marsh fringe during the short period under the rough weather condition.

关键词： current velocity suspended sediment content flux salt marsh eastern beach

Breast Cancer Diagnosis via Support Vector Machines

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Breast Cancer Diagnosis via Support Vector Machines

The Promoting Effect on the Activities ofFe Doped TiO_2 Photocatalysts

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作者： wang Yi,Wan Fuyong department of mathematics,east china normal university,Shanghai 200062,{4. department of mathematics,east china normal university,Shanghai 200062,{4.

＜正＞This paper describes the application of SVM to breast cancer diagnosis,which has shown good generalization. We take use of non-symmetrical C-SVM to solve the problem of unbalanced training examples. In order to gain a fastsearching method for parameters of the model,a margin-based bound on generalization is more effective than traditionalk -fold cross-validation. After feature subset selection by a cross-entry filter,we even gained a perfect prediction accuracy.

关键词： Breast Cancer Diagnosis Non-symmetrical C-SVM Generalization Bound Cross-entropy Filter

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Chemical Research in Chinese Universities 2001年第2期17卷 187-192页

作者： YU Xi-bin, wang Gui-hua and LI He-xing (department of Chemistry, Shanghai normal university, Shanghai 200234. P. R. {4.) Shanghai normal Univ Dept Chem Shanghai 200234 Peoples R China

The particles of titanium-iron (Ti/Fe) complex with different Fe contents were prepared by means of the sol-gel method and used as a photocatalyst. The activity of the catalyst was investi- gated as a function of the Fe content during the liquid-phase oxidation of tetracycline, which showed an enhancement at the low Fe content. The XRD, Raman, XPS, and UV-Vis absorp- tion spectra indicated that the crystalline structure of the Ti/Fe complex particles changed from anatase phase to rutile phase when the Fe content increased. The isolated Fe203, Fe304. FeO species were observed and Fe3+ ions were highly dispersed in the TiO2 matrixes, then Ti-O-Fe species were formed. These species increased the surface defects of the Ti/Fe particles. Also, ac- tive hydroxyl radicals could be generated in the catalytic transformation, which led to the higher activity of the catalyst than bare Ti02 for the degradation of tetracycline.

关键词： Titanium Fe doped photocatalyst Photocatalytic activity Tetracycline

EXISTENCE　OF　NONTRIVIAL　SOLUTIONS　FOR　CRITICAL　SEMILINEAR　BIHARMONIC　EQUATIONS

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Systems Science and Mathematical Sciences 1994年第2期7卷 140-152页

作者： GU Yonggeng(Institute of Systems Science, Academia Sinica, Beijing 100080, china)DENG Yinbin(department of mathematics, Huazhong normal {4. ,Wuhan 4.0070, china)wang Xujia(department of mathematics, Zhejiang {4., Hangzhou 310027, china)

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关键词： Nontrivial solution biharmonic equations critical Sobolev exponent.

The Lifetime of Diffusion Processes with Application to Conditioned Diffusions

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Acta Mathematica Sinica,English Series 1998年第3期14卷 381-384页

作者： wang Fengyu department of mathematics, Beijing normal {4., Beijing 100875, china Email: wangfy@*** department of mathematics Beijing Normal Universily

Let τ_D denote the lifetime of a diffusion process on domain DR^d. This paper presents a sufficient condition for the exponential moment of τ_D to be finite. Here, both of the domain and the diffusion operator are g... 详细信息

关键词： Lifetime Diffusion process Conditioned diffusion

Travelling wave solutions of a generalized Camassa-Holm-Degasperis-Procesi equation

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Science china mathematics 2011年第3期54卷 555-572页

作者： DENG ShengFu1, GUO BoLing2 & wang TingChun2,3 1department of mathematics, Zhanjiang normal {4., Zhanjiang 524.4., china 2Institute of Applied Physics and Computational mathematics, Beijing 100088, china 3 College of Math and Physics, Nanjing {4. of Information Science and Technology, Nanjing 21004., china 1. department of mathematics Zhanjiang Normal University Zhanjiang 524048 China2. Institute of Applied Physics and Computational Mathematics Beijing 100088 China3. College of Math and Physics Nanjing University of Information Science and Technology Nanjing 210044 China

The travelling wave solutions of a generalized Camassa-Holm-Degasperis-Procesi equation ut-uxxt + (1 + b)umux = buxuxx + uuxxx are considered where b > 1 and m are positive integers. The qualitative analysis methods of planar autonomous systems yield its phase portraits. Its soliton wave solutions, kink or antikink wave solutions, peakon wave solutions, compacton wave solutions, periodic wave solutions and periodic cusp wave solutions are obtained. Some numerical simulations of these solutions are also given.

关键词： homoclinic orbits heteroclinic orbits peakon wave solutions compacton wave solutions periodic cusp wave solutions