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Infragravity waves with internal wave characteristics in the south of the Bohai Sea of China

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Acta Oceanologica Sinica 2003年第2期22卷 171-178页

作者： fan Zhisong, Gao Guoping, Yin Xunqiang, fan yu, wu Wei Marine Environment College,Ocean University of China,Qingdao 266003, China Ocean Univ China Marine Environm Coll Qingdao 266003 Peoples R China

The measurements by using ADCP (500 KH) and CTD were made during August 2000in the south (37?5'N, 120?5'E) of the Bohai Sea, where the water depth was about 16.5 m. The data of horizontal velocity with sampling interval of 2 min in 7 layers were obtained. The power spectrum analysis of these data indicates that there are very energetic infragravity waves with a period of about 6 min. The coherence spectrum analysis and the analysis of temporal variation of shear show that these infragravity waves are mainly the free wave model (properties of edge waves), in the meantime they possess some characteristics of internal waves, which are likely due to the distinctive marine environment in this area. It is speculated on that the instability processes (chiefly shear instability) of sheared stratified tidal flow owing to the effect of sea-floor slope in the coastal area might be the main mechanism generating these infragravity waves.

关键词： Infragravity waves edge waves internal waves vertical shear of horizontal velocity internal mixing

Primary prostate Burkitt's lymphoma resected with holmium laser enucleation of the prostate:A rare case report

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World Journal of Clinical Cases 2023年第18期11卷 4406-4411页

作者： yu-fan wu Xiang Li Jun Ma Dan-yu Ma Xue-Ming Zeng Qi-Wei yu Wei-Guo Chen Department of Urology Kunshan Hospital of Traditional Chinese MedicineKunshan 215300Jiangsu ProvinceChina Department of Urology The First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina Department of Oncology The Third Affiliated Hospital of Soochow UniversitySuzhou 215300Jiangsu ProvinceChina

BACKGROUND Primary prostate Burkitt's lymphoma is a rare and aggressive condition with a poor *** clinical presentation can be challenging to differentiate from benign prostatic *** the rarity of primary prostate Burkitt's lymphoma,its diagnosis and treatment remain *** SUMMARY This report presents a case of a 57-year-old male with primary prostate Burkitt's lymphoma,initially misdiagnosed as prostatic *** case's operative process,intraoperative findings and postoperative management are discussed in *** Primary prostate lymphoma is difficult to distinguish from other prostate *** laser enucleation of the prostate(HoLEP),a minimally invasive procedure,is crucial in diagnosing and treating this rare *** should remain vigilant and thoroughly combine physical examination,imaging and test results when encountering patients of younger age with small prostate size but a rapid progression of lower urinary tract *** is an essential diagnostic and therapeutic tool in managing primary prostate Burkitt's lymphoma.

关键词： Primary prostate Burkitt's lymphoma Holmium Laser enucleation of the prostate Prostate hyperplasia Case report

The molecular control of meiotic double-strand break (DSB) formation and its significance in human infertility

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Asian Journal of Andrology 2021年第6期23卷 555-561页

作者： Yang Li yu-fan wu Han-Wei Jiang Ranjha Khan Qi-Qi Han Furhan Iqbal Xiao-Hua Jiang Qing-Hua Shi Division of Reproduction and Genetics First Affiliated Hospital of USTCHefei National Laboratory for Physical Sciences at Microscalethe CAS Key Laboratory of Innate Immunity and Chronic DiseaseSchool of Basic Medical SciencesDivision of Life Sciences and MedicineCAS Center for Excellence in Molecular Cell ScienceCollaborative Innovation Center of Genetics and DevelopmentUniversity of Science and Technology of ChinaHefei 230027China Institute of Pure and Applied Biology Bahauddin Zakariya UniversityMultan 60000Pakistan

Meiosis is an essential step in gametogenesis which is the key process in sexually reproducing organisms as meiotic aberrations may result in infertility. In meiosis, programmed DNA double-strand break (DSB) formation is one of the fundamental processes that are essential for maintaining homolog interactions and correcting segregation of chromosomes. Although the number and distribution of meiotic DSBs are tightly regulated, still abnormalities in DSB formation are known to cause meiotic arrest and infertility. This review is a detailed account of molecular bases of meiotic DSB formation, its evolutionary conservation, and variations in different species. We further reviewed the mutations of DSB formation genes in association with human infertility and also proposed the future directions and strategies about the study of meiotic DSB formation.

关键词： DNA double-strand break(DSB) infertility meiosis mutation

Two New Dihydroflavanoids from Patrinia vittosa Juss (II)

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Chinese Chemical Letters 2006年第4期17卷 485-488页

作者： Jin Yong PENG Guo Rong fan yu Tian wu Shanghai Key Laboratory for Pharmaceutical Metabolite Research School of Pharmacy Second Military Medical University Shanghai 200433

Two new dihydroflavonoids named villosin A and viUosin B were obtained from the traditional Chinese medicinal herb Patrinia viUosa Juss. Their structures were elucidated as （2S）-5, 2＇, 6＇-trihydroxy-2＂, 2＂-dimethylpyrano [5＂, 6＂： 6, 7]flavanone 1 and （2S, 3＂S）-5, 2＇, 6＇- trihydroxy-3＂-γ, γ-dimethylallyl-2＂, 2＂-dimethyl-3＂, 4＂-dihydropyrano [5＂, 6＂： 6, 7] flavanone 2 by spectroscopic methods including UV, IR, HR-TOF- MS, 1D NMR and 2D NMR techniques.

关键词： Patrinia villosa Juss dihydroflavonoids.

Endoscopic full-thickness resection using an over-the-scope device:A prospective study

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World Journal of Gastroenterology 2021年第8期27卷 725-736页

作者： Jin-Tao Guo Jing-Jing Zhang yu-fan wu Ye Liao Yi-Dan Wang Bao-Zhen Zhang Sheng Wang Si-yu Sun Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND Endoscopic submucosal dissection to treat mucosal and submucosal lesions sometimes results in low rates of microscopically margin-negative(R0)*** full-thickness resection(EFTR)has a high R0 resection rate and allows for the definitive diagnosis and treatment of selected mucosal and submucosal lesions that are not suitable for conventional resection *** To evaluate the efficacy and safety of EFTR using an over-the-scope clip(OTSC).METHODS This prospective,single-center,non-randomized clinical trial was conducted at the endoscopy center of Shengjing Hospital of China Medical *** study included patients aged 18-70 years who had gastric or colorectal submucosal tumors(SMTs)(≤20 mm in diameter)originating from the muscularis propria based on endoscopic ultrasound(EUS)and patients who had early-stage gastric or colorectal cancer(≤20 mm in diameter)based on EUS and computed *** lesions were treated by EFTR combined with an OTSC for wound closure between November 2014 and October *** analyzed patient demographics,lesion features,histopathological diagnoses,R0 resection(negative margins)status,adverse events,and follow-up *** A total of 68 patients(17 men and 51 women)with an average age of 52.0±10.5 years(32-71 years)were enrolled in this study,which included 66 gastric or colorectal SMTs and 2 early-stage colorectal *** mean tumor diameter was 12.6±4.3 *** EFTR procedure was successful in all *** mean EFTR procedure time was 39.6±38.0 *** mean OTSC defect closure time was 5.0±3.8 min,and the success rate of closure for defects was 100%.Histologically complete resection(R0)was achieved in 67(98.5%)***-related adverse events were observed in 11(16.2%)*** average post-procedure length of follow-up was 48.2±15.7 *** was no recurrence during *** EFTR combined with an OTSC is an effective and safe technique for the removal of select sube

关键词： Endoscopic full-thickness resection Over-the-scope clip Early gastric cancer Early colorectal cancer Submucosal tumor Gastrointestinal stromal tumor

Endoscopic fenestration in the diagnosis and treatment of delayed anastomotic submucosal abscess:A case report and review of literature

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World Journal of Clinical Cases 2020年第23期8卷 6086-6094页

作者： Bao-Zhen Zhang Yi-Dan Wang Ye Liao Jing-Jing Zhang yu-fan wu Xiao-Lin Sun Si-yu Sun Jin-Tao Guo Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Endoscopy Center Liaoyang Liaohua HospitalLiaoyang 111000Liaoning ProvinceChina

BACKGROUND Abscess formation is one of the complications after radical resection of rectal cancer;cases with delayed postoperative anastomotic abscess are ***,we report a rare case of postoperative anastomotic abscess with a submucosal neoplasm appearing after rectal ***,the patient was diagnosed and treated by endoscopic *** addition,we review the literature on the appearance of an abscess as a complication after rectal cancer *** SUMMARY A 57-year-old man with a history of rectal malignancy resection complained of a smooth protuberance near the anastomotic *** ultrasonography revealed a hypoechoic structure originating from the muscularis propria,and a submucosal tumor was *** patient was subsequently referred to our hospital and underwent pelvic contrast-enhanced computed tomography,which revealed no thickening or strengthening of the anastomotic *** order to clarify the origin of the lesion and obtain the pathology,endoscopic fenestration was *** endoscopic procedure,a definitive diagnosis of delayed anastomotic submucosal abscess was *** patient achieved good recovery and prognosis after the complete clearance of *** Endoscopic fenestration may be safe and effective for the diagnosis/treatment of delayed intestinal smooth protuberance after rectal cancer surgery.

关键词： Anastomotic stoma Rectal cancer Submucosal tumor Endoscopic fenestration Delayed postoperative abscess Case report

Efficacy of endoscopic ultrasound in the evaluation of small gastrointestinal stromal tumors

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World Journal of Gastroenterology 2022年第37期28卷 5457-5468页

作者： Qi-Chao Ge yu-fan wu Zi-Ming Liu Zhe Wang Sheng Wang Xiang Liu Nan Ge Jin-Tao Guo Si-yu Sun Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Pathology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND Gastrointestinal stromal tumors(GISTs)with a diameter of5/50 high power field in 8(3.1%)*** irregularity,ulceration,strong echo foci,and heterogeneity were detected in 1(0.4%),2(0.8%),22(8.6%),and 67(65.1%)... 详细信息

BACKGROUND Gastrointestinal stromal tumors(GISTs)with a diameter ofwup method for GISTs,which can also provide a preliminary basis for judging the malignancy potential of ***,there are no studies on the accuracy of EUS to assess the malignant potential of small *** To evaluate the efficacy of EUS in the diagnosis and risk assessment of small *** We collected data from patients with small GISTs who were admitted to Shengjing Hospital of China Medical University between October 2014 and July *** accurate diagnosis and risk classifications of patients were based on the pathological assessment according to the modified National Institute of Health criteria after endoscopic resection or laparoscopic *** EUS features(marginal irregularity,cystic changes,homogeneity,ulceration,and strong echogenic foci)were retrospectively *** assessment results based on EUS features were compared with the pathological *** A total of 256 patients(69 men and 187 women)were *** results included 232,16,7,and 1 very low-,low-,intermediate-,and high-risk cases,*** most frequent tumor location was the gastric fundus(78.1%),and mitoses were calculated as>5/50 high power field in 8(3.1%)*** irregularity,ulceration,strong echo foci,and heterogeneity were detected in 1(0.4%),2(0.8%),22(8.6%),and 67(65.1%)patients,***,cystic changes were not *** size was positively correlated with the mitotic index(P1.48 cm was associated with higher risk classification(P1.48 cm)with positive EUS features should receive intensive surveillance or unde

关键词： Gastrointestinal stromal tumors Endoscopic ultrasound Diagnosis Risk classification

Endoscopic ultrasound-measured muscular thickness of the lower esophageal sphincter and long-term prognosis after peroral endoscopic myotomy for achalasia

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World Journal of Gastroenterology 2020年第38期26卷 5863-5873页

作者： Ye Liao Ting-yue Xiao yu-fan wu Jing-Jing Zhang Bao-Zhen Zhang Yi-Dan Wang Sheng Wang XiangLiu Si-yu Sun Jin-Tao Guo Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Science and Education Shenyang Sixth People’s HospitalShenyang 110006Liaoning ProvinceChina

BACKGROUND People with achalasia typically have a thick lower esophageal muscularis propria(LEMP),and peroral endoscopic myotomy(POEM)has been effective in treating most *** thickness may be associated with the outcomes and prognosis after ***,more evidence is needed regarding the relationship between LEMP thickness and patient prognosis after *** To assess the association between LEMP thickness,measured using endoscopic ultrasound(EUS),and long-term prognosis,especially relapse,after POEM for *** All medical records,including EUS data,of patients who underwent POEM to treat achalasia at Shengjing Hospital of China Medical University from January 2012 to September 2018 were retrospectively *** thickness was measured by EUS,and a thickness of≥3 mm was defined as *** severity of patient symptoms was evaluated using the Eckardt *** was defined as a 3-point rise in the Eckardt score after a period of clinical *** relationship between patient characteristics,muscle thickness,and recurrence was *** Eighty-two patients(32 males and 50 females,aged 17-78 years)and 85 POEM procedures were *** total,76.8%(63/82 patients)of patients had a thickened muscularis *** age and longer disease course were associated with muscularis propria thickening(P3 refused further management after their symptoms were *** relapse rate was 12.73%(7/55 cases).Five patients,four of whom had muscularis propria thickening,had disease recurrence within 12 mo after the *** relapsed in one patient who had a thickened muscularis propria after 24 mo and in another patient who did not have a thickened muscularis propria after 30 *** with recurrence were typically younger and had a shorter disease course(P<0.05).The relapse rate in patients with

关键词： Peroral endoscopic myotomy Achalasia Endoscopic ultrasound

Comprehensive review of diagnostic modalities for early chronic pancreatitis

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World Journal of Gastroenterology 2021年第27期27卷 4342-4357页

作者： Qi-Chao Ge Christoph F Dietrich Manoop S Bhutani Bao-Zhen Zhang yue Zhang Yi-Dan Wang Jing-JingZhang yu-fan wu Si-yu Sun Jin-Tao Guo Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department Allgemeine Innere Medizin Salem und PermanenceBern CH-3000Switzerland Department of Gastrointestinal Hepatology and NutritionThe University of Texas MD Anderson Cancer CenterHoustonTX 77030United States

Chronic pancreatitis(CP)is a progressive condition caused by several factors and characterised by pancreatic fibrosis and ***,CP is difficult to diagnose at an early *** advanced methods including endoscopic ultrasound based elastography and confocal laser endomicroscopy have been used to diagnose early CP,although no unified diagnostic standards have been *** the past,the diagnosis was mainly based on imaging,and no comprehensive evaluations were *** review describes and compares the advantages and limitations of the traditional and latest diagnostic modalities and suggests guidelines for the standardisation of the methods used to diagnose early CP.

关键词： Chronic pancreatitis Pancreatic fibrosis Early diagnosis Ultrasound endoscopy Endosonography Elastography Confocal laser endomicroscopy