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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第6期18卷 539-543页

作者： Ye-sheng XU Wen-jia XIE yu-feng yao Department of Ophthalmology Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016China

Objective：To report surgical management and favorable outcome in a case with delayed repair of traumatic laser in situ keratomileusis（LASIK）flap dislocation with shrinkage and ***：A 30-year-old man with a five-year history of bilateral LASIK experienced blunt trauma to his right eye followed by decreased vision for 5 *** surgical management included initially softening the flap by irrigation with balanced salt solution（BSS）.The shrinkage folds were carefully and gently stretched by scraping with a 26-gauge cannula accompanied by BSS *** of the epithelial ingrowth on the flap inner surface and on the bed was thoroughly debrided by scraping and *** the flap was repositioned to match its original margin,a soft bandage contact lens was ***：At his initial visit,slit-lamp microscopy and optical coherence tomography（OCT）showed shrinkage of the LASIK flap with an elevated margin approximately 3 mm above the original *** flap covered half of the pupil and had multiple horizontal *** months after surgery,the flap remained well positioned with only faint streaks in the anterior *** uncorrected visual acuity of the right eye was 20/20 with a manifest refraction of ***：For delayed repair of traumatically dislocated LASIK flaps,sufficient softening by BSS,stretching the shrinkage folds,and thorough debridement of ingrowth epithelium enable resetting the flap and provide satisfactory results.

关键词： Delayed repositioning Laser in situ keratomileusis(LASIK) Traumatic flap dislocation

Multi-Robot Cooperative Localization:Time-Varying Unobservable Subspace Analysis and Consistent Algorithm Design

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Journal of Systems Science & Complexity 2024年第5期37卷 1937-1955页

作者： HAO Ning HE fenghua yao yu School of Astronautics Harbin Institute of TechnologyHarbin 150000China

This paper investigates the problem of cooperative localization(CL)for a multi-robot system(MRS)under dynamic measurement topology,which involves a group of robots collectively estimating their poses with respect to a common reference frame using ego-motion measurements and robot-to-robot relative *** authors provide a theoretical analysis of the time-varying unobservable subspace and propose a consistent cooperative localization ***,the authors introduce the relative measurement graph(RMG)to represent the relative pose measurements obtained by the MRS at each ***,the authors derive the local observability matrix over a time *** equivalent relationship is established between the local observability matrix and the spectral matrices of the ***,the authors present a method for constructing the unobservable subspace based on the RMG under different topology *** on this analysis,the authors design a consistent cooperative localization algorithm that satisfies the constraints of the time-varying unobservable *** analytical optimal solution is derived for the constrained optimization *** Carlo numerical simulations are conducted to demonstrate the consistency and accuracy of the proposed method.

关键词： Consistency cooperative localization multi-robot system null space relative measurement graph time-varying unobservable subspace

Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第3期19卷 218-226页

作者： Wen-jia XIE Ye-sheng XU Xia ZHANG yu-feng yao Department of Ophthalmology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou 310016 China

Objective： To assess the lower tear meniscus height（LTMH）, central tear film thickness（CTFT）, and central corneal epithelial thickness（CCET） after deep anterior lamellar keratoplasty（DALK）. Methods： This was a retrospective cross-sectional study of 20 patients who had DALK in one eye over a three-month period. LTMH, CTFT, and CCET of the operated eyes and the unoperated fellow eyes were measured using high-definition optical coherence tomography（HD-OCT）. Correlations between three OCT assessments and age, time following surgery, graft size, bed size, and the number of residual sutures were analyzed. Results： Compared to patients with keratoconus, patients with other corneal conditions had significantly higher CCET in the fellow eye（P=0.024）. For all patients, CCET in the operated eye was significantly negatively correlated with the number of residual sutures（R=-0.579, P=0.008）, and was significantly positively correlated with time following surgery（R=0.636, P=0.003）. In the fellow eye, a significant positive correlation was found between age and CCET（R=0.551, P=0.012）, and a significant negative correlation between age and CTFT（R=-0.491, P=0.028）. LTMH was found to be significantly correlated between operated and fellow eyes（R=0.554, P=0.011）. There was no significant correlation between LTMH and age, bed/graft size, time following surgery, or residual sutures（all possible correlations, P0.05）. Conclusions： Patients with keratoconus tend to have a thinner central corneal epithelium. Corneal epithelium keeps regenerating over time after DALK. DALK did not induce a significant change in tear volume compared with the fellow eye. Postoperative tear function might depend on an individual＇s general condition, rather than on age, gender, bed/graft size, time following surgery, or residual sutures.

关键词： Tear meniscus height Corneal epithelial thickness Tear film Deep anterior lamellar keratoplasty (DALK) High-definition optical coherence tomography (HD-OCT) Keratoconus

Development of a scintillating-fiber-based beam monitor for the coherent muon-to-electron transition experiment

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Nuclear Science and Techniques 2024年第4期35卷 156-164页

作者： yu Xu yun-Song Ning Zhi-Zhen Qin yao Teng Chang-Qing feng Jian Tang yu Chen Yoshinori Fukao Satoshi Mihara Kou Oishi School of Physics Sun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China High Energy Accelerator Research Organization(KEK) Ibaraki 305‑0801Japan Department of Physics Imperial College LondonLondon SW72AZUK

The coherent muon-to-electron transition(COMET)experiment is a leading experiment for the coherent conversion of μ^(-)N→e^(-)N using a high-intensity pulsed muon beamline,produced using innovative slow-extraction ***,it is critical to measure the muon beam *** set up a muon beam monitor(MBM),where scintillating fibers woven in a cross shape were coupled to silicon photomultipliers to measure the spatial profile and timing structure of the extracted muon beam for the *** MBM detector was tested successfully with a proton beamline at the China Spallation Neutron Source and took data with good performance in the commissioning *** development of the MBM,including its mechanical structure,electronic readout,and beam measurement results,are discussed.

关键词： Beam instrumentation Profile monitor Scintillating fiber Silicon photomultipliers

Effects of corneal thickness distribution and apex position on postoperative refractive status after full-bed deep anterior lamellar keratoplasty

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第11期19卷 863-870页

作者： Bing-hong WANG Ye-sheng XU Wen-jia XIE yu-feng yao Department of Ophthalmology Sir Run Run Shaw Hospital Zhejiang University School of Medicine

Objective： To investigate the effects of corneal thickness distribution and apex position on postoperative refractive status after full-bed deep anterior lamellar keratoplasty （FBDALK）. Methods： This is a retrospective analysis of patients who were diagnosed with advanced keratoconus between 2011 and 2014 in our hospital. The base of the cone in all patients did not exceed the central cornea at a 6-mm range. The FBDALK was performed by a same surgeon. All patients had a complete corneal suture removal and the follow-up records were intact. Patients who had graft-bed misalignment or who were complicated with a cataract or glaucoma were excluded. Uncorrected visual acuity （UCVA）, best spectacle corrected visual acuity （BSCVA）, and Pentacam examination data were recorded at two years postoperatively. The recorded data included the superior-inferior （S-I） and nasal-temporal （N-T） corneal thickness differences in 2, 4, 6, and 8 mm diameter concentric circles with the corneal apex as the center （S-I2 mm, S-14 mm, S-I6mm,, S-I8mm, N-T2mm, N-T4 mm, N-T6 mm, and N-T8 mm）, the linear, X-axis, and Y-axis distance between the corneal pupillary center and the cornea apex, total corneal astigmatism at a zone of 3 mm diameter from the corneal apex （TA3 mm）, the astigmatic vector values J0 and J4s, and the corneal total higher-order aberration for 3 and 6 mm pupil diameters （HOA3 mm and HOA6mm）. Statistical analysis was performed by SPSS 15.0. Results： A total of 47 eyes of 46 patients met the criteria and were included in this study. The mean follow-up time was （28±7） months. The mean UCVA was 0.45±0.23 （IogMAR）（MAR： minimum angle of resolution） and the mean BSCVA was 0.19±0.15 （IogMAR）, which were all sig- nificantly positively correlated with postoperative TA3 mm and HOA3 turn. The mean S-I corneal thickness differences were （44.62±37.74） IJm, and the mean N-T was （38.57±32.29） pm. S-12 mm was significantly positively correlated with J0 （r=0.31）, J45 （r=0.42）, HOA3 mm （r=0.37）,

关键词： Full-bed deep anterior lamellar keratoplasty Corneal thickness distribution Corneal apex

Facilitating prelithiation of silicon carbon anode by localized high-concentration electrolyte for high-rate and long-cycle lithium storage

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Carbon Energy 2024年第6期6卷 216-233页

作者： yuanxing Zhang Borong Wu Jiaying Bi Xinyu Zhang Daobin Mu Xin-yu Zhang Ling Zhang yao Xiao feng Wu School of Materials Science and Engineering Beijing Institute of TechnologyBeijingChina Chongqing Innovation Center Beijing Institute of TechnologyChongqingChina College of New Energy Xi′an Shiyou UniversityXi′anChina Institute for Carbon Neutralization College of Chemistry and Materials EngineeringWenzhou UniversityWenzhouChina Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjinChina

The commercialization of silicon-based anodes is affected by their low initial Coulombic efficiency(ICE)and capacity decay,which are attributed to the formation of an unstable solid electrolyte interface(SEI)***,a feasible and cost-effective prelithiation method under a localized highconcentration electrolyte system(LHCE)for the silicon-silica/graphite(Si-SiO_(2)/C@G)anode is designed for stabilizing the SEI layer and enhancing the *** thin SiO_(2)/C layers with-NH_(2) groups covered on nano-Si surfaces are demonstrated to be beneficial to the prelithiation process by density functional theory calculations and electrochemical *** SEI formed under LHCE is proven to be rich in ionic conductivity,inorganic substances,and flexible organic ***,faster Li+transportation across the SEI further enhances the prelithiation effect and the rate performance of Si-SiO_(2)/C@G *** also leads to uniform decomposition and high stability of the SEI with abundant organic *** a result,the prepared anode shows a high reversible specific capacity of 937.5 mAh g^(-1)after 400 cycles at a current density of 1 *** 811‖Li-SSGLHCE full cell achieves a high-capacity retention of 126.15 mAh g^(-1)at 1 C over 750 cycles with 84.82%ICE,indicating the great value of this strategy for Si-based anodes in large-scale applications.

关键词： localized high-concentration electrolytes prelithiation SEI layer silicon anode

Utilizing dual-pathway energy transfer in upconversion nanoconjugates for reinforced photodynamic therapy

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Nano Research 2024年第4期17卷 2941-2948页

作者： Ruohao Zhang yu Lu Yifei Zhou Kehong Lv Xinyu Fu Jitong Gong Shuang yao Xiaozhen Wang Jing feng Hongjie Zhang State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China College of Chemistry Jilin UniversityChangchun 130012China Department of Breast Surgery General Surgery Centerthe First Hospital of Jilin UniversityChangchun 130021China Department of Chemistry Tsinghua UniversityBeijing 100084China

Enhancing the therapeutic effect of existing treatments or developing new non-invasive treatments are important measures to achieve high-efficiency treatment of malignant *** therapy(PDT)is an emerging treatment modality,and the key for achieving high-efficiency PDT is to select light with strong tissue penetration depth and enhance the generation of reactive oxygen species(ROS).Although the upconversion nanoparticles(UCNPs)modified with the photosensitizers could achieve PDT with strong penetration depth under near-infrared light irradiation,the ROS generated by traditional single-pathway PDT is still ***,we developed a novel nanoconjugate(UCNP-Ce6/AIEgen)for dual-pathway reinforced PDT,in which the UCNPs were co-modified with chlorin e6(Ce6)and luminogen with aggregation-induced emission(AIEgen).Due to the presence of AIEgen,UCNP-Ce6/AIEgen could avoid aggregation-caused luminescence quenching in biological water environments and convert upconversion luminescence(UCL)of UCNPs to Ce6-activatable ***,under the irradiation of 808 nm laser,UCNP-Ce6/AIEgen can not only undergo direct lanthanide-triplet energy transfer to activate Ce6,but also convert the UCL of UCNPs to the light that can activate Ce6 through Fӧrster resonance energy transfer to generate more ROS,thus promoting tumor cell *** work broadens the applications of nanoconjugates of lanthanide-based inorganic materials and organic dyes,and provides a conception for reinforced PDT of tumors.

关键词： upconversion nanoparticle aggregation-induced emission direct lanthanide-triplet energy transfer Förster resonance energy transfer photodynamic therapy

Dietary saccharin sodium supplementation improves the production performance of dairy goats without residue in milk in summer

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Animal Nutrition 2024年第3期18卷 166-176页

作者： Xiongfei Zhang Jirong Lv Jingtao Hui Ao Wu Lichao Zhao Linyu feng Lu Deng Miao yu feng Liu Junhu yao Xinjian Lei College of Animal Science and Technology Northwest A&F UniversityYanglingShaanxi 712100China Key Laboratory of Livestock Biology Northwest A&F UniversityYanglingShaanxi 712100China Sichuan Provincial Animal Feeding Regulation Center DadHank Biotechnology CorporationChengduSichuan 611130China

The purpose of this study was to investigate the effects of dietary saccharin sodium supplementation on production performance,serum biochemical indicators,and rumen fermentation of dairy goats in *** Guanzhong dairy goats with similar body weight,days in milk,and milk yield were randomly divided into two dietary treatments:(1)CON:basal diet;(2)SS:basal diet+150 mg/kg saccharin sodium on the basis of dry *** experiment lasted 35 d,including 7 d for adaptation and 28 d for dietary treatments,sampling and data *** dairy goat was housed individually in a clean separate pen with ad libitum access to diet and *** goats fed SS diet had increased dry matter intake(DMI;P=0.037),4%fat corrected milk yield(P=0.049),energy corrected milk yield(P=0.037),milk protein yield(P=0.031),and total solids yield(P=0.036).Serum activity of aspartate aminotransferase(P=0.047)and concentrations of 70-kDa heat shock protein(P=0.090),malondialdehyde(P=0.092),and total protein(P=0.057)were lower in goats fed SS diet than those fed CON *** of saccharin sodium tended to increase activity of glutathione peroxidase in serum(P=0.079).The concentrations of rumen total volatile fatty acid(P=0.042)and butyrate(P=0.038)were increased by saccharin sodium *** supplementation of saccharin sodium increased the relative abundance of Lachnobacterium(P=0.022),Pseudoramibacter(P=0.022),Shuttleworthia(P=0.025),and Syntrophococcus(P=0.037),but reduced the relative abundance of Prevotella_1(P=0.037)and Lachnospiraceae_UCG_008(P=0.037)in *** sodium was observed in feces and urine of goats fed diet supplemented with saccharin sodium,but saccharin sodium was undetectable in the milk of goats receiving SS *** conclusion,administration of saccharin sodium was effective in increasing fat and energy corrected milk yield by increasing DMI and improving rumen fermentation and antioxidant capacity of dairy goats in *** addition,s

关键词： Dairy goat Heat stress Production performance Rumen fermentation Rumen microorganisms Saccharin sodium

Event-Triggered Bipartite Consensus Tracking and Vibration Control of Flexible Timoshenko Manipulators Under Time-Varying Actuator Faults

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1190-1201页

作者： Xiangqian yao Hao Sun Zhijia Zhao yu Liu School of Automation Science and Engineering South China University of TechnologyGuangzhou 510640China Yongjiang Laboratory Ningbo 315202 School of Astronautics Harbin Institute of TechnologyHarbin 150001China School of Mechanical and Electrical Engineering Guangzhou UniversityGuangzhou 510006China

For bipartite angle consensus tracking and vibration suppression of multiple Timoshenko manipulator systems with time-varying actuator faults,parameter and modeling uncertainties,and unknown disturbances,a novel distributed boundary event-triggered control strategy is proposed in this *** contrast to the earlier findings,time-varying consensus tracking and actuator defects are taken into account *** addition,the constructed event-triggered control mechanism can achieve a more flexible design because it is not required to satisfy the input-to-state *** achieve the control objectives,some new integral control variables are given by using back-stepping technique and boundary ***,adaptive neural networks are applied to estimate system *** the proposed event-triggered scheme,control inputs can reduce unnecessary ***,tracking errors and vibration states of the closed-looped network can be exponentially convergent into some small fields,and Zeno behaviors can be *** last,some simulation examples are given to state the effectiveness of the control algorithms.

关键词： Vibration satisfy bipartite

Estimation of the anisotropy of hydraulic conductivity through 3D fracture networks using the directional geological entropy

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International Journal of Mining Science and Technology 2024年第2期34卷 137-148页

作者： Chuangbing Zhou Zuyang Ye Chi yao Xincheng Fan feng Xiong School of Infrastructure Engineering Nanchang UniversityNanchang 330031China b School of Resource and Environmental Engineering Wuhan University of Science and TechnologyWuhan 430081China School of Engineering China University of GeosciencesWuhan 430074China

With an extension of the geological entropy concept in porous media,the approach called directional entrogram is applied to link hydraulic behavior to the anisotropy of the 3D fracture networks.A metric called directional entropic scale is used to measure the anisotropy of spatial order in different *** with the traditional connectivity indexes based on the statistics of fracture geometry,the directional entropic scale is capable to quantify the anisotropy of connectivity and hydraulic conductivity in heterogeneous 3D fracture *** to the numerical analysis of directional entrogram and fluid flow in a number of the 3D fracture networks,the hydraulic conductivities and entropic scales in different directions both increase with spatial order(i.e.,trace length decreasing and spacing increasing)and are independent of the dip *** a result,the nonlinear correlation between the hydraulic conductivities and entropic scales from different directions can be unified as quadratic polynomial function,which can shed light on the anisotropic effect of spatial order and global entropy on the heterogeneous hydraulic behaviors.

关键词： 3D fracture network Geological entropy Directional entropic scale Anisotropy Hydraulic conductivity