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Effect of aortic valve replacement on ventricular recovery and functional class in patients with reduced left ventricular function

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World Journal of Cardiovascular Diseases 2013年第9期3卷 543-550页

作者： Mahdi Ait Houssa Younes Moutakiallah Abdessamad Abdou Abdedaim Hatim mohamed Drissi Brahim Amahzoune youssef El Bekkali Atif Benyass Abdelatif Boulahya Cardiac Surgery Department Mohammed V Military HospitalRabatMorocco ICU of Cardiac Surgery Department Mohammed V Military HospitalRabatMorocco Cardiology Department Mohammed V Military HospitalRabatMorocco

Objective: The aim of the study was to assess the effects of aortic valve replacement (AVR) in patients with aortic stenosis (AS) or regurgitation (AR) and left ventricular (LV) dysfunction. Patients and methods: Retrospective analysis identified 75 consecutive patients with left ventricular ejection fraction (LVEF) assessed by echocardiography < 40% who underwent AVR for AS (n = 40) or AR (n = 35) between 1994 and 2011. Exclusion criteria were previous myocardial infarction or concomitant valvular disorders other than aortic disease. Follow-up evaluated the New York Heart Association (NYHA) functional class, LVEF and survival rate. Results: Mean ages were respectively 56.5 ± 9.3 and 47.9 ± 11.7 years in AS and AR groups, p = 0.001. Before surgery, 88% and 75% of patients were in NYHA III-IV respectively in AS and AR. In the AS group, the mean LVEF and aortic valve area (AVA) were respectively 32.2% ± 8% and 0.65 ± 0.15 cm2. AR group had a mean LVEF of 33.8 ± 6.7% and a mean LV systolic diameter of 62 ± 8.8 mm. All patients underwent AVR under cardiopulmonary bypass. There were 5 operative deaths (12.5%) in AS group and 6 (17.6%) in AR group, p = 0.57. LVEF increased to 49% ± 14.7% and 51.2% ± 10.9% in the AS and AR groups after echocardiography control. The survival rates at 1, 5 and 10 years were respectively 94.4%, 87% and 80% in AS group and 95.2%, 93% and 89% in AR group. Conclusion: Despite higher perioperative mortality in patients with aortic valve disease (AS or AR) and LV dysfunction, long-term outcome is excellent. We, therefore, conclude that AVR can be performed and it should not be denied to patients on the basis of low EF alone.

关键词： Aortic Valve Disease Aortic Valve Replacement Left Ventricular Dysfunction

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Distinct and combined impacts of climate and land use scenarios on water availability and sediment loads for a water supply reservoir in northern Morocco

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International Soil and Water Conservation Research 2020年第2期8卷 141-153页

作者： Fatiha Choukri Damien Raclot Mustapha Naimi mohamed Chikhaoui Joao Pedro Nunes Frédéric Huard Cécile Hérivaux mohamed Sabir Yannick Pépin IAV Hassan II Department of Natural Resources and EnvironmentMadinat Al IrfaneRabatMorocco LISAH Univ MontpellierINRAEIRDInstitut AgroMontpellierFrance CE3C-Centre for Ecology Evolution and Environmental ChangesFaculdade de CienciasUniversidade de Lisboa1749-016LisboaPortugal INRAE-AgroClim 228 Route de l’AérodromeCS 4050984914AvignonCedex 9France BRGM Univ Montpellier1039 Rue de Pinville34000MontpellierFrance ENFI bd Moulay YoussefTabriquetSALEMorocco

The objective of this study was to examine the impacts of climate and land use changes on wateravailability and sediment loads for a water supply reservoir in northern Morocco using data-intensive simulation models in a data-scarce region. Impacts were assessed by comparing the simulated water and sediment entering the reservoir between the future period 2031-2050 and the 1983-2010 reference period. Three scenarios of land use change and two scenarios of climate change were developed in the Tleta watershed. Simulations under current and future conditions were performed using the Soil and Water Assessment Tool (SWAT) model. The simulations showed that climate change will lead to a sig-nificant decrease in the annual water supply to the reservoir (-16.9% and -27.5%) and in the annual volume of sediment entering the reservoir (-7.4% and -12.6%), depending on the climate change sce-narios tested. The three scenarios of land use change will lead to a moderate change in annual water inflow into the reservoir (between-6.7% and +6.2%), while causing a significant decrease in sediment entering the reservoir (-37%to-24%). The combined impacts of climate and land use changes will cause a reduction in annual water availability (-9.9%to-33.3%) and sediment supplies (-28.7%to-45.8%). As a result, the lifetime of the reservoir will be extended, but at the same time, the risk of water shortages will increase, especially from July to March. Therefore, alternative water resources must be considered.

关键词： Climate change Land use change SWAT Runoff Reservoir management Morocco

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Mineralogy and Geochemistry of EtekéEburnean Gold Deposit (Gabon)

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Open Journal of Geology 2022年第3期12卷 294-311页

作者： Makarim Dalil Nazaire Nzaou Mabika Amina Wafik Zohir Baroudi Abdelmalek Ouadjou mohamed Gharrabi Amine Bouwafoud Nouamane El Aouad youssef Zerhouni Saida Alikouss Laboratoire géosciences et applications Faculté des sciences Ben M’sik Casablanca Morocco Laboratoire Dynamique de la Lithosphère et Genèse des Ressources Faculté des Sciences Semlalia Marrakech Morocco Managem Group Twin Center Casablanca Morocco

The Gabon geology offered favorable and natural environments for the formation of various types of mineralization. The Etéké gold district, aim of this study, is located in the Ngounié province (southern Gabon) on the western edge of the Chaillu massif. Geologically, the gold mineralization is associated with the Eburnean orogeny and hosted in the Archean greenstone belts. Also, this deposit is covered by a significant vegetation cover and a very extensive lateritic weathering profile, which hinders the most accurate study. Through this paper, we aim to propose a genesis pattern of this mineralization via a multidisciplinary approach. To do this, a petrographic, metallogenic, and geochemical characterization has been established in the different sectors of the Etéké deposit. The studied deposits display varied facies which are encased in granitoid. They are essentially formed of abundant granitoid, and amphibolite compared to the volcano-sedimentary formations. These rocks display magmatic textures, affected by metamorphism, and not sufficiently preserved. Based on our multidisciplinary approach, the studied samples collected from the core’s boreholes allowed us to decipher a volcanogenic and metamorphosed origin of the gold genesis.

关键词： Eburnean Orogeny Gabon Gold Greenstone Granitoids Amphibolite

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Elimination of Hepatitis C in Liver Transplant Recipients

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Journal of Clinical and Translational Hepatology 2018年第3期6卷 247-250页

作者： Sammy Saab youssef Challita Phillip H.Chen Melissa A.Jimenez Alex D.Lee Elena G.Saab Timothy Ahn Gina Choi Francisco A.Durazo mohamed M.El-Kabany Steven-Huy B.Han Jonathan Grotts Vatche G.Agopian Ronald W.Busuttil Department of Medicine University of California at Los AngelesLos AngelesCaliforniaUSA Department of Surgery at the University of California at Los Angeles Los AngelesCaliforniaUSA

Background and Aims:Recurrent hepatitis C(HCV)disease in liver transplant(LT)recipients is associated with significant morbidity and *** the availability of noninterferon-based therapy,eliminating HCV may be achievable in LT ***:We studied all consecutive recipients who underwent LT at the University of California Los Angeles be-tween January 2005 and June *** collected data on date of transplant and last follow-up,as well as laboratory *** also recorded type and timing of antiviral therapy relative to *** were performed to assess the proportion of LT recipi-ents who are viremic after ***:Six hundred thirty-four patients underwent LTwith a diagnosis of *** was a statistically significant trend for patients to be cured be-fore(p<0.001)and after liver transplantation(p<0.001)for the study period of 2014 to 2016 relative to 2005 and 2013,*** the 634 recipients eligible for therapy,8%and 74%were treated within 12 months of transplant for the study periods 2005 to 2013 and 2014 to 2016,*** was a significant decrease between the two study periods in the proportion of patients undergoing re-LT 1 year after the original LT:5.5%(n=28/510)and 1.5%(n=2/124)respec-tively for study periods 2005 to 2013 and 2014 to 2016 respec-tively(p=0.011).Conclusions:The proportion of LTrecipients who are viremic has decreased over *** HCV in LT recipients is feasible after the introduction of direct-acting *** HCV should translate to improved clinical out-comes in LT recipients who were transplanted for HCV infection with longer *** results suggest the de-creased need for transplant in the direct-acting agents era.

关键词： Hepatitis C Direct-acting agents Liver transplant Elimination

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Antioxidant and diuretic activity of co-administration of Capparis spinosa honey and propolis in comparison to furosemide

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Asian Pacific Journal of Tropical Medicine 2017年第10期10卷 974-980页

作者： Soukaina El-Guendouz Noori Al-Waili Smail Aazza youssef Elamine Soumia Zizi Thia Al-Waili Ali Al-Waili Badiaa Lyoussi Laboratory Physiology-Pharmacology&Environmental Health Faculty of Sciences Dhar-MahrazUniversity Sidi Mohamed Ben AbdallahFezMorocco New York Medical Care for Nephrology Richmond HillNew York 11418USA

Objective: To study the antioxidant properties of Capparis spinosa(***) honey and propolis and the effect of combined honey and propolis administration on urine volume and electrolytes in ***: *** honey [1 000 mg/kg body weight(***)], propolis(100 mg/kg ***), honey/propolis mixture(*** honey 1 000 mg/kg ***/propolis extract 100 mg/kg ***), distilled water(1 mL/kg ***) and furosemide(10 mg/kg ***) were orally administered to fi ve groups of rats for 21 *** volume, blood and urine sodium,potassium and chloride were *** antioxidant activity of propolis and honey was assessed and their total phenols and flavonoids were ***: Propolis and *** honey contain polyphenols including flavonoids and propolis demonstrated higher antioxidant activities than *** significantly increased urine volume and urine electrolyte *** had no significant effect on urine volume, but co-administration of propolis and honey caused significant *** major changes were observed in plasma electrolytes with the use of honey, propolis or their ***: Honey and propolis have antioxidant activity and contain polyphenols including flavonoids that are more pronounced in *** has a significant diuretic activity alone or in combination with *** is the first study comparing the diuretic effect of co-administration of propolis and *** honey with furosemide.

关键词： Honey Propolis Antioxidants Diuresis Sodium Potassium

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Effects of Transportation Stress during the Hot-Dry Season on Some Haematological and Physiological Parameters in Moroccan Dromedary Camels （Camelus dromedarius）

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Journal of Life Sciences 2013年第1期7卷 13-25页

作者： Mohammed El Khasmi youssef Chakir Fouad Riad Abdallah Safwate E1 Hassane Tahri mohamed Farh Najia E Abbadi Rachid Abouhafs Bernard Faye Laboratory of Physiopathology and Molecular Genetics Faculty of Sciences Ben M'Sik University Hassan II-Mohammedia Casablanca 20000 Morocco Unit of Applied Radioimmunology National Center for Energy Sciences and Techniques and Nuclear Techniques Maamoura Morocco Prefectural Veterinary Service of Casablanca Casablanca 20000 Morocco CIRAD-ES International Campus of Baillarguet Montpellier 34398 Cedex 5 France

The purpose of this study was to determine the effects of road transportation under heat conditions on some haematological [Ht （haematocrit）, blood cells count and EOF （erythrocytes osmotic fragility）] and physiological [Tr （rectal temperature）, HR （heart） and RR （respiratory rates）, and circulating levels of Cor （cortisol）, Glu （glucose） and minerals] parameters in Moroccan dromedary camels. The animals were subjected to road transportation stressor for 2 h by truck during the hot-dry season. Blood samples were collected before loading and transport, and at the end of transport. Transportation induced a significant increase （P 〈 0.05） of erythrocytes count, Ht, EOF, Tr, HR and RR by comparison to values observed before transportation. The same stress conditions induced a significant increase （P 〈 0.05） of plasma Cor （ng/mL） and blood Glu （mM）（220 ± 30 vs. 137 ± 20, 9.7 ± 1.2 vs. 6.4 ± 1. 1 respectively） and a significant decrease （P 〈 0.05） of plasma magnesium （mM）（0.5 ± 0.1 vs. 0.9 ± 0.1） comparatively to pre-transportation values. These results indicate that road transportation associated to heat may be considered as a potent stressor which is able to induce several cellular alterations in camels. Further studies of an eventual protective role of vitamin C against haemolysis induced by transportation stress in camel are needed.

关键词： Cortisol dromedary camel glucose haemolysis hot-dry season minerals transportation stress.

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Knowledge, Attitudes and Perception of Moroccan Women about Breast Cancer

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Journal of Health Science 2016年第6期4卷 290-296页

作者： Nadia Benaicha Hafida Charaka Ousmane Desire Samira Elfakir Nabil Tachfouti mohamed Berraho youssef Chami Khazraji Loubna Abousselham Latifa Belakhel Rachid Bekkali Chakib Nejjari Department of Epidemiology and Clinical Research Faculty of Medicine Fez Morocco Foundation Lalla Salma Prevention and Treatment of Cancers Rabat Morocco Direction of Population Ministry of Health Rabat Morocco Direction of Epidemiology and Fight against Diseases (DELM) Ministry of Health Rabat Morocco

Breast cancer appears to be a disease of both the developing and developed worlds. Among Moroccan women, breast cancer represents 34.4% of all cancers seen in women. This study aimed to give an overview of the knowledge, attitudes and perceptions related to breast cancer among Moroccan women. To our knowledge there is no previous study in Morocco to assess Moroccan women awareness of breast cancer. A national Cross-sectional study started in July 2011 based on eligible women for early detection programs in basal health centers from five Moroccan regions. A self-filled questionnaire was used to collect data outside working time. Knowledge was assessed using 24 true-false items. The questions were asked about symptoms and risk factors of breast cancer. A score ranging from 0 to 24 was calculated by weighting each item 1 point. Then the score was dichotomized according to the threshold 12 （50% correct answers）. The study included 1,444 women from the regions of Rabat, Casablanca, Marrakech, Fez and Meknes. The average age was 40.6 ~ 10 years, 2 women with a minimum age of 17 years and a 1 with a maximum age of 86 years. At the bivariate analysis using chi-square test we found that Marital Status, Social Security, Education, Origin, Sport, Personal History of Cancer, Medical and Surgical personal History were associated with knowledge score. At the multivariate analysis （Logistic regression）, we found that Social Security, Education, Origin, Sport were associated to knowledge score at the final model. This study has important implications for health care providers. The poor knowledge of risk factors and practice of breast screening leads to late stage presentation at diagnosis of breast cancer.

关键词： Cancer women Morocco perception.

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Metakaolin as an Active Pozzolan for Cement That Improves Its Properties and Reduces Its Pollution Hazard

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Journal of Minerals and Materials Characterization and Engineering 2018年第1期6卷 86-104页

作者： Suzan S. Ibrahim Ayman A. Hagrass Tawfik R. Boulos Samir I. youssef Fouad I. El-Hossiny mohamed R. Moharam Central Metallurgical Research and Development Institute Cairo Egypt El-Tabbin Institute for Metallurgical Studies Cairo Egypt Faculty of Science Ain Shams University Cairo Egypt Faculty of Engineering Azhar University Cairo Egypt

Prepared metakaolin produced by calcination of a kaolin sample at 750°C after soaking for 5 hrs was tested as an active pozzolan for locally produced cement. Blended pastes of partially replaced ordinary Portland cement with different metakaolin amounts 5%, 10% and 15% were prepared, then they were hydrated with water for various time intervals of 1, 3, 7, 14 and 28 days. At each time interval, the hydrated paste specimens were tested for compressive strength, hydration kinetics and followed up using differential scanning calorimetry, X-ray diffractometry analyses and scanning electron microscopy techniques. Results showed that the blended pastes OPC-MK10 recorded the highest compressive strength values at all the hydration times reaching 33.10, 86.40, 101.20, 112, and 122 MPa with increasing the age of hydration as compared with the neat samples which recorded 31.70, 65.20, 72.6, 82 and 101.30 MPa respectively. Meanwhile, the OPC-MK10 blend showed a decrease in the free CaO content reaching 4.07%, 4.27%, 4.23%, 4.19%, and 4.11% CaO with increasing age of hydration compared with the neat samples which recorded 4.27%, 5.15%, 5.42%, 5.61%, and 5.96% CaO respectively. The DSC thermograms results for the hardened neat and OPC-Mk10 pastes at the 14 and 28 hydration days showed the formation of hydrated materials mainly calcium silicate hydrates, calcium sulphoaluminate hydrates and calcium aluminates hydrates. The X-ray diffractometry analyses of both hardened neat and OPC- MK10 showed that, the intensity of calcium hydroxide peaks of OPC-MK10 was lower than in case of neat OPC, while the peak of the hydration products of calcium silicate hydrates and calcium aluminates silicate hydrates of OPC- MK10 samples were of higher intensity than in case of neat OPC. Scanning electron microscopy micrographs indicated the formation of denser micro- structure for the hardened OPC-MK10 paste as compared to neat OPC pastes after the 28 days age of hydration.

关键词： Metakaolin Compressive Strengths Hydration Kinetics

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农业排水管理对氮流失于地表水的影响(英文)

农业排水管理对氮流失于地表水的影响(英文)

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2009水资源与可持续发展高层论坛

作者： R.Wayne Skaggs mohamed A.youssef W.N.Reynolds Dist.Univ.Professor and Assistant Professor respectively North Carolina State UniversityRaleighNC27695-7625

＜正＞Nitrogen losses from drained agricultural lands are a principal source of excess nitrogen（N） in streams and *** Water Management（DWM） or Controlled Drainage（CD） can be used to significantly reduce N losses in drainage waters while conserving water and potentially increasing crop *** research conducted by a number of investigators on a wide range of soils and locations has shown that CD reduced N losses by 18 to 85 percent compared to conventional *** of results of the various studies indicates that the difference in effectiveness of CD among soils and sites is primarily due to differences in its effect on seepage,and whether the seepage water passes through dentirified *** leads to the conclusion that research to determine the effectiveness of CD should be conducted on field size or larger units,such that the effect of lateral and vertical seepage will be appropriately *** simulation model DRAINMOD was used to predict the long-term performance of CD for a sandy loam soil in eastern North *** reduced the 35-year average annual predicted N losses in drainage water by 37%for continuous corn and by 34%for a corn-wheat-soybean rotation. Both predicted N loads in drainage water and the reduction of those loads in response to CD varied widely from year to *** annual N loads for conventional drainage on continuous corn varied from 12.3 to 87.3 kg/*** reduced the predicted annual N loads in drainage water by 18 to 58%over the 35 year period.

关键词： Controlled Drainage Water Quality DRAINMOD Nitrogen Models

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Surgery in the Acute Phase of Infective Endocarditis: 5 Years after Our Initial Experience

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World Journal of Cardiovascular Diseases 2016年第8期6卷 275-284页

作者： youssef El Bekkali Noureddine Atmani Siham Bellouize mohamed Drissi Younes Moutakiallah Mehdi Bamous Abdessamad Abdou Fouad Nya Anis Seghrouchni Mahdi Aithoussa Brahim Amahzoune Abdedaim Hatim Ghadbane Abdelatif Boulahya Cardiac Surgery Department Mohammed V Military Hospital Rabat Morocco Reanimation of Cardiac Surgery Department Mohamed V Medical Faculty Rabat Morocco

Aim: Comparing the results of acute phase infectious endocarditis surgery between two periods. Methods and Results: The study is about 2 series, series A between 1993 and 1997, and series B between 1998 and 2012, respectively 13 and 51 patients. The two periods were similar concerning the number of patients per year, which was 3.12 cases/year for series A and 3.64 cases/year for series B. The authors noted a change in epidemiological profile, with an increase of median age (31 y.o for series A and 37 y.o for series B), and the emergency of endocarditis on prosthetic valve (none on series A and 8 cases for series B). Surgical indications and results didn’t change too much, hospital mortality rate was 15.3% for series A and 17.6% for series B. Conclusion: Infectious endocarditis is still a major public healthcare problem in developing countries, despite the development of diagnostic tools and patient care. Prevention is still the major asset in the treatment of this disease.

关键词： Infectious Endocarditis Acute Phase Surgery

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