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Iterative Semi-Supervised Learning Using Softmax Probability

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Computers, Materials & Continua 2022年第9期72卷 5607-5628页

作者： Heewon chung Jinseok Lee Department of Biomedical Engineering College of Electronics and InformationKyung Hee UniversityYongin-siGyeonggi-do17104Korea

For the classification problem in practice,one of the challenging issues is to obtain enough labeled data for ***,even if such labeled data has been sufficiently accumulated,most datasets often exhibit long-tailed distribution with heavy class imbalance,which results in a biased model towards a majority *** alleviate such class imbalance,semisupervised learning methods using additional unlabeled data have been ***,as a matter of course,the accuracy is much lower than that from supervised *** this study,under the assumption that additional unlabeled data is available,we propose the iterative semi-supervised learning algorithms,which iteratively correct the labeling of the extra unlabeled data based on softmax *** results show that the proposed algorithms provide the accuracy as high as that from the supervised *** validate the proposed algorithms,we tested on the two scenarios:with the balanced unlabeled dataset and with the imbalanced unlabeled *** both scenarios,our proposed semi-supervised learning algorithms provided higher accuracy than previous *** is available at https://***/Heewonchung92/iterative-semi-learning.

关键词： Semi-supervised learning class imbalance iterative learning unlabeled data

A review of regenerative therapies as penile rehabilitation in men following primary prostate cancer treatment:Evidence for erectile restoration and cavernous nerve regeneration

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Asian Journal of Urology 2022年第3期9卷 287-293页

作者： Eric chung AndroUrology Centre BrisbaneQLDAustralia University of Queensland Princess Alexandra HospitalBrisbaneQLDAustralia Macquarie University Hospital SydneyNSWAustralia

Objective:The following article explores our evolving understandings of the role of regenerative technology as an effective penile rehabilitation tool in men with erectile dysfunction(ED)in the setting of prostate cancer(PCa)treatment and PCa ***:This narrative clinical review paper summarizes what is currently known about various modalities of regenerative therapy in restoring spontaneous erectile function(EF)in men following PCa treatment with an emphasis on penile rehabilitation ***:Conventional medical therapy often does not reverse underlying endothelial dysfunction or promote neuro-vasculogenesis to preserve penile health in men with *** the past decade,there has been considerable interest in the role of regenerative therapy to restore endothelial dysfunction and ED without future dependency on medical *** therapy can be classified into cellular-based(immunomodulators,stem cells,and platelet-rich plasma),biomaterials(nerve graft transfer),and device-related technology(low-intensity shockwave).Although published literature shows early promise in the role of regenerative technology for ED,there is a paucity of high-quality clinical trials in the setting of penile rehabilitation and PCa survivorship to support their use as standard care and be adopted in clinical guidelines.

关键词： Regenerative therapy Low-intensity shockwave therapy Stem cell therapy Platelet-rich plasma Immunomodulator Nerve transfer Erectile dysfunction Penile rehabilitation

Autocompletion of repetitive stroking with image guidance

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Computational Visual Media 2023年第3期9卷 581-596页

作者： Yilan Chen Kin chung Kwan Hongbo Fu School of Creative Media City University of Hong KongTat Chee AvenueKowloonHong Kong SARChina University of Konstanz University Street 1078464 KonstanzGermany

Image-guided drawing can compensate for a lack of skill but often requires a significant number of repetitive strokes to create *** automatic stroke synthesis methods are usually limited to predefined styles or require indirect manipulation that may break the spontaneous flow of *** present an assisted drawing system to autocomplete repetitive short strokes during a user's normal drawing *** draw over a reference image as usual;at the same time,our system silently analyzes the input strokes and the reference to infer strokes that follow the user's input style when certain repetition is *** can accept,modify,or ignore the system's predictions and continue drawing,thus maintaining fluid control over *** key idea is to jointly analyze image regions and user input history to detect and predict *** proposed system can effectively reduce the user's workload when drawing repetitive short strokes,helping users to create results with rich patterns.

关键词： interaction autocompletion digital drawing prediction texture synthesis

VANET Jamming and Adversarial Attack Defense for Autonomous Vehicle Safety

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Computers, Materials & Continua 2022年第5期71卷 3589-3605页

作者： Haeri Kim Jong-Moon chung Department of Vehicle Convergence Engineering Yonsei UniversitySeoul03722Korea School of Electrical&Electronic Engineering Yonsei UniversitySeoul03722Korea

The development of Vehicular Ad-hoc Network(VANET)technology is helping Intelligent Transportation System(ITS)services to become a *** can use VANETs to communicate safety messages on the road(while driving)and can inform their location and share road condition information in ***,intentional and unintentional(e.g.,packet/frame collision)wireless signal jamming can occur,which will degrade the quality of communication over the channel,preventing the reception of safety messages,and thereby posing a safety hazard to the vehicle’s *** this paper,VANET jamming detection applying Support Vector Machine(SVM)machine learning technology is used to classify jamming and non-jamming *** analysis is based on two cases which include normal traffic and heavy traffic conditions,where the results show that the probability of packet dropping will increase when many vehicles are using the wireless channel *** using SVM classification,the most appropriate feature set applied in determining a jamming situation shows an accuracy of 98%or ***,more advanced jamming attacks need to be considered for preparation of more reliable and safer autonomous ITS *** research can use vehicular communication transmission and reception data based on selected published *** this paper,an additional adversarial defense algorithm using the Density-Based Spatial Clustering of Applications with Noise(DBSCAN)method is proposed,which assumes that evolutionary attacks of the jammer will attempt to confuse the trained *** simulation results show that applying DBSCAN can improve the accuracy by elimination of outliers before conducting classification testing.

关键词： Vehicle safety VANET jamming SVM adversarial defense

Explainable Anomaly Detection Using Vision Transformer Based SVDD

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Computers, Materials & Continua 2023年第3期74卷 6573-6586页

作者： Ji-Won Baek Kyungyong chung Department of Computer Science Kyonggi UniversitySuwon-si 16227Korea Division of AI Computer Science and Engineering Kyonggi UniversitySuwon-si 16227Korea

Explainable AI extracts a variety of patterns of data in the learning process and draws hidden information through the discovery of semantic *** is possible to offer the explainable basis of decision-making for inference *** the causality of risk factors that have an ambiguous association in big medical data,it is possible to increase transparency and reliability of explainable decision-making that helps to diagnose disease *** addition,the technique makes it possible to accurately predict disease risk for anomaly *** transformer for anomaly detection from image data makes classification through ***,in MLP,a vector value depends on patch sequence information,and thus a weight *** should solve the problem that there is a difference in the result value according to the change in the *** addition,since the deep learning model is a black box model,there is a problem that it is difficult to interpret the results determined by the ***,there is a need for an explainablemethod for the part where the disease *** solve the problem,this study proposes explainable anomaly detection using vision transformerbasedDeep Support Vector Data Description(SVDD).The proposed method applies the SVDD to solve the problem of MLP in which a result value is different depending on a weight change that is influenced by patch sequence information used in the vision *** order to draw the explainability of model results,it visualizes normal parts through *** health data,both medical staff and patients are able to identify abnormal parts *** addition,it is possible to improve the reliability of models and medical *** performance evaluation normal/abnormal classification accuracy and f-measure are evaluated,according to whether to apply *** Results The results of classification by applying the proposed SVDD are evaluated ***,through the proposed meth

关键词： Explainable AI anomaly detection vision transformer SVDD health care deep learning classification

Glycan targeting nanoparticle for photodynamic immunotherapy of melanoma

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Acta Pharmaceutica Sinica B 2023年第5期13卷 1903-1918页

作者： yonghyun Choi Wooic Son Youngpin Han Jayoung chae Chul-Su Yang Jonghoon Choi School of Integrative Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Molecular&Life Science Hanyang UniversityAnsan 15588Republic of Korea Center for Bionano Intelligence Education and Research Hanyang UniversityAnsan 15588Republic of Korea

Interaction between tumour cells and macrophages enables cancer cells to evade immune detection and clearance by interfering with macrophage *** anti-phagocytic signals regulated by anti-phagocytic proteins are termed"don't eat me"signals;these signals include sialic acidbinding immunoglobulin-type lectin-10(Siglec-10)and the recently revealed CD24 immune checkpoint(ICP).In this study,we demonstrate that targeting a specific glycan on CD24 exhibits the potential to inhibit *** nigra agglutinin(SNA),a sialic acid-binding lectin,was employed to block CD24 and to enhance phagocytosis in melanoma *** addition,we prepared SNA-conjugated hollow gold-iron oxide nanoparticles for photothermal therapy of *** findings show that the combination treatment of SNA-conjugated photothermal nanoparticles and near-infrared exposure successfully augments tumour cell phagocytosis both in vitro and in vivo models.

关键词： Immunotherapy Macrophages Phagocytosis Lectin Melanoma cancer Photothermal nanoparticles Immune checkpoint Glycan

Effects of dispersoid preforming via multistep sintering of oxide dispersion-strengthened CoCrFeMnNi high-entropy alloy

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Journal of Materials Science & Technology 2023年第9期140卷 187-200页

作者： SeungHyeok chung Ji Ho Shin Ho Jin Ryu Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Central Research Institute Korea Hydro and Nuclear Power Co.Ltd.(KHNP)Daejeon 34101Republic of Korea

Dispersoid formation and microstructural evolution in an oxide dispersion-strengthened CoCrFeMnNi high-entropy alloy(HEA)using a newly designed multistep sintering process are *** proposed multistep sintering consists of a dispersoid preforming heat treatment of as-milled 0.1 wt%Y_(2)O_(3)-CoCrFeMnNi high-entropy alloy powders at 800℃,followed by sintering at 800–1000℃ under uniaxial *** the conventional single-step sintered bulk,the coarsened BCC Y_(2)O_(3)dispersoids mainly form with an incoherent interface with the HEA *** contrast,finer FCC Y_(2)O_(3)dispersoids,an atypical form of Y_(2)O_(3),are formed in the matrix region after multistep *** of FCC Y_(2)O_(3)disper-soids is initiated on the favorable facet,the{111}plane of the austenitic matrix,with the formation of a semi-coherent interface with the matrix during the dispersoid preforming heat treatment and it maintains its refined size even after *** is found that dispersoid preforming prior to sintering appears promising to control the finer dispersoid formation and refined grain structure.

关键词： Oxide dispersion strengthening High-Entropy alloy Multistep sintering Dispersoid preforming Microstructure evolution Interfacial structure

Woody plant cell walls:Fundamentals and utilization

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Molecular Plant 2024年第1期17卷 112-140页

作者： Wei Li Ying-chung Jimmy Lin Ying-Lan Chen Chenguang Zhou Shuang Li Nette De Ridder Dyoni M.Oliveira Lanjun Zhange Baocai Zhang Jack P.Wang Changzheng Xu Xiaokang Fu Keming Luo Ai-Min Wu Taku Demura Meng-Zhu Lu Yihua Zhou Laigeng Li Toshiaki Umezawa Wout Boerjan Vincent L.Chiang State Key Laboratory of Tree Genetics and Breeding Northeast Forestry UniversityHarbin 150040China Department of Life Science National Taiwan UniversityTaipeiTaiwanChina Department of Biotechnology and Bioindustry Sciences College of Bioscience and BiotechnologyNational Cheng Kung UniversityTainanTaiwanChina Department of Plant Biotechnology and Bioinformatics Ghent UniversityTechnologiepark 719052 GhentBelgium VIB Center for Plant Systems Biology Technologiepark 719052 GhentBelgium State Key Laboratory of Plant Genomics Insttute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Forest Biotechnology Group Department of Forestry and Environmental ResourcesNorth Carolina State UniversityRaleighNC 27695USA Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation Integrative Science Center of Germplasm CreationSchool of Life SciencesSouthwest UniversityChongqing 400715China Guangdong Key Laboratory for Innovative Developmentand Utilization of Forest Plant Germplasm College of Forestry and Landscape ArchitecturesSouth China Agricultural UniversityGuangzhou510642China Center for Digital Green-innovation Nara Institute of Science and TechnologykomaNara 630-0192Japan State Key Laboratory of Subtropical Siviculture College of Forestry and BiotechnologyZhejang A&F UniversityHangzhou 311300China CAS Center for Excellence in Molecular Plant Sciences Chinese Academy of Sciences300 Fenglin RoadShanghai 200032China Laboratoryof MetabolicScienceofForest Plants and Microorganisms Rsearch Institute for Sustainable HumanosphereKyoto UniversityUjiKyoto 611-0011 Japan

Cell walls in plants,particularly forest trees,are the major carbon sink of the terrestrial *** and biosynthetic features of plant cell walls were revealed early on,focusing mostly on herbaceous model *** developments in genomics,transcriptomics,epigenomics,transgenesis,and associated analytical techniques are enabling novel insights into formation of woody cell ***,we review multilevel regulation of cell wall biosynthesis in forest tree *** highlight current approaches to engineering cell walls as potential feedstock for materials and energy and survey reported field tests of such engineered transgenic *** outline opportunities and challenges in future research to better understand cell type biogenesis for more efficient wood cell wall modification and utilization for biomaterials or for enhanced carbon capture and storage.

关键词： regulation of cell wall formation biosynthesis of cell wall components lignin cellulose hemicellulose cell wall utilization

Isoniazid and Pulmonary Fibrosis

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Chinese Medical Journal 2015年第5期128卷 702-703页

作者： chae Uk chung Dong II Park Choong Sik Lee Sung Soo Jung Department of Internal Medicine Division of Pulmonology College of Medicine Chungnam National University Deajeon 301-721 Korea Department of Pathology College of Medicine Chungnam National University Deajeon 301-721 Korea

To the Editor：The anti-tuberculosis （TB） therapy can cause various drug adverse effects including hepatotoxicity,nephrotoxicity and skin rash.[1,2] There are some case reports about interstitial lung disease （ILD...

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