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High‑Entropy Electrode Materials:Synthesis,Properties and Outlook

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Nano-Micro Letters 2025年第1期17卷 472-506页

作者： Dongxiao li Chang liu Shusheng Tao Jieming Cai Biao zhong Jie li Wentao Deng Hongshuai Hou Guoqiang Zou Xiaobo Ji College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083People’s Republic of China School of Chemistry and Chemical Engineering Hunan Institute of EngineeringXiangtan 411104People’s Republic of China

High-entropy materials represent a new category of high-performance materials,first proposed in 2004 and extensively investigated by researchers over the past two *** definition of high-entropy materials has continuously *** the last ten years,the discovery of an increasing number of high-entropy materials has led to significant advancements in their utilization in energy storage,electrocatalysis,and related domains,accompanied by a rise in techniques for fabricating high-entropy electrode ***,the research emphasis has shifted from solely improving the performance of high-entropy materials toward exploring their reaction mechanisms and adopting cleaner preparation ***,the current definition of high-entropy materials remains relatively vague,and the preparation method of high-entropy materials is based on the preparation method of single metal/low-or medium-entropy *** should be noted that not all methods applicable to single metal/low-or medium-entropy materials can be directly applied to high-entropy *** this review,the definition and development of high-entropy materials are briefly ***,the classification of high-entropy electrode materials is presented,followed by a discussion of their applications in energy storage and catalysis from the perspective of synthesis ***,an evaluation of the advantages and disadvantages of various synthesis methods in the production process of different high-entropy materials is provided,along with a proposal for potential future development directions for high-entropy materials.

关键词： High-entropy Energy storage Electrode materials

Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

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Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen Chen Xiaolin Zeng Le Wang Wenwu Zhang Gang li Xing Cheng Peiqiang Su yong Wan Xiang li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury

Expression of sigma receptor 1 in rat retina

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Expression of sigma receptor 1 in rat retina

The Citron homology domain of MAP4Ks improves outcomes of traumatic brain injury

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Lei-Lei liU,Lu WANG,yong-Mei zhong~*,Xiong-li YANG Institute of Neurobiology,Institute of Brain Science and State Key Laboratory of Medical Neurobiology,Fudan University,Shanghai 200032,China

＜正＞Sigma receptors（aRs） are nonopiate,nonphencyclidine binding sites in mammalian brain and peripheral organs, distinct from other known *** are thought to have neuroprotective role via modulation of N-methyl-Daspartate （NMDA） *** date,two types of oRs（oRl andσR2） have been *** this work,expression ofσR1 in rat retina was studied using immunofluorescence double labeling and confocal laser scanning *** blot analysis demonstrated that the antibody was specific in rat *** transcription-polymerase chain reactive （RT-PCR） analysis showed thatσR1 mRNA was present in rat *** forσR1 was diffusely distributed throughout the full thickness of the inner plexiform ***σR1 -immunoreactivity（IR） was also observed in lots of cells in the inner nuclear layer and in the ganglion cell ***σR1-IR was detectable in the outer *** labeling experiments further showed thatσR1 was expressed in a population of glycinergic amacrine cells（ACs） as well as glycine-labeled bipolar cells（BCs） that could be cone ON type *** labeling was seen in parvalbumin-positive All *** addition,σR1-IR was also seen in almost all somata of ganglion cells retrogradely labeled by *** results suggest thatσR1 may play neuroprotective roles for neurons in the inner retina.

关键词： σR1 immunofluorescence double labeling amacrine cells ganglion cells retina

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Neural Regeneration Research 2025年第11期20卷 3233-3244页

作者： Xiaoling zhong Wenjiao Tai Meng-Lu liu Shuaipeng Ma Tianjin Shen Yuhua Zou Chun-li Zhang Department of Molecular Biology University of Texas Southwestern Medical CenterDallasTXUSA Hamon Center for Regenerative Science and Medicine University of Texas Southwestern Medical CenterDallasTXUSA Peter O’Donnell Jr.Brain Institute University of Texas Southwestern Medical CenterDallasTXUSA

The mitogen-activated protein kinase kinase kinase kinases(MAP4Ks)signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following *** targeting this pathway is beneficial to brain injury remains *** this study,we showed that adeno-associated virus-delivery of the Citron homology domain of MAP4Ks effectively reduces traumatic brain injury-induced reactive gliosis,tauopathy,lesion size,and behavioral *** inhibition of MAP4Ks replicated the ameliorative effects observed with expression of the Citron homology ***,the Citron homology domain acted as a dominant-negative mutant,impeding MAP4K-mediated phosphorylation of the dishevelled proteins and thereby controlling the Wnt/β-catenin *** findings implicate a therapeutic potential of targeting MAP4Ks to alleviate the detrimental effects of traumatic brain injury.

关键词： adeno-associated virus Citron homology Citron homology domain gene therapy mitogen-activated protein kinase kinase kinase kinases traumatic brain injury

高抗冲及强表面附着力PET合金的制备与性能研究

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塑料工业 2018年第10期46卷 91-94页

作者：邓小亮周欣肖勇钟鹏李俊峰普拉斯包装材料有限公司聚酯事业部四川宜宾644007

采用聚乙烯-辛烯共聚弹性体(POE)接枝马来酸酐(POE-g-MAH)增韧聚对苯二甲酸乙二醇酯(PET),同时为了提高PET/POE-g-MAH产品的电镀性能,通过乙烯丙烯酸类聚合物(EAA)对合金进行增黏改性。冲击测试表明,POE-g-MAH能够大幅度提高PET的抗冲... 详细信息

采用聚乙烯-辛烯共聚弹性体(POE)接枝马来酸酐(POE-g-MAH)增韧聚对苯二甲酸乙二醇酯(PET),同时为了提高PET/POE-g-MAH产品的电镀性能,通过乙烯丙烯酸类聚合物(EAA)对合金进行增黏改性。冲击测试表明,POE-g-MAH能够大幅度提高PET的抗冲击性能,结合公司产品使用环境以及成本,选择添加10%POE-g-MAH用于提高PET韧性能够达到综合性能优异、成本低的要求。另外,加入增黏剂后,PET/POE-g-MAH共混体系的冲击强度先上升后下降,当EAA含量为2%时,附着力与冲击强度均较大,并且底座电镀后百格测试油漆无脱落。

关键词：聚对苯二甲酸乙二醇酯附着力电镀增韧

人巨细胞病毒cDNA文库的构建、鉴定及pp65阳性克隆筛选

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微生物学通报 2004年第2期31卷 87-90页

作者：韩俊李艳秋姜永中余莉王明丽安徽医科大学微生物学教研室

为进一步进行人巨细胞病毒 (HCMV)后基因组功能的研究 ,以及为疫苗分子和早期诊断试剂的研制提供有效工具 ,从HCMVAD1 69株感染 96h的HF细胞中提取HCMV的mRNA ,逆转录合成cDNA片段 ,重组入λgt1 1EcoRI酶切位点之间 ,包装蛋白包装 ,构建... 详细信息

为进一步进行人巨细胞病毒 (HCMV)后基因组功能的研究 ,以及为疫苗分子和早期诊断试剂的研制提供有效工具 ,从HCMVAD1 69株感染 96h的HF细胞中提取HCMV的mRNA ,逆转录合成cDNA片段 ,重组入λgt1 1EcoRI酶切位点之间 ,包装蛋白包装 ,构建HCMVAD1 69株基因组cDNA表达文库。结果表明 ,初始HCMVcDNA文库容量为 3 6× 1 0 6,重组率为 96% ;HCMV鼠多克隆抗血清筛选出 1 68个HCMV阳性克隆 ;地高辛标记pp65特异性寡核苷酸探针原位噬斑杂交筛选出 3 4个pp65阳性克隆 ,再经PCR扩增 ,筛选出 2个pp65阳性克隆 ;pp65PCR扩增产物进一步被Southernblotting证实 ;3 端测序比较 ,同源性为 98%。为进一步克隆。

关键词：人巨细胞病毒 pp65 cDNA表达文库

Activation of the sigma receptor 1 modulates NMDA receptors in rat retinal ganglion cells

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Activation of the sigma receptor 1 modulates NMDA receptors ...

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Xin-Jun ZHANG,Lei-Lei liU,yong-Mei zhong,Xiong-li YANG~* Institute of Neurobiology,Institutes of Brain Science and State Key Laboratory of Medical Neurobiology,Fudan University,Shanghai 200032,China

Sigma receptors(oRs) represent unique nonopiate,nonphencyclidine binding sites in mammalian nervous *** is evidence that ligands of aRs have robust neuroprotective *** the present work,we investigated howσR1 is expressed in the rat retina and how activation ofσR1 modulates NMDA receptors in rat retinal ganglion cells (GCs).By immunocytochemistry,we showed thatσR1 was strongly expressed in the somata of amacrine cells and GCs. Labeling forσR1 was also observed in both outer and inner plexiform *** blotting demonstrated thatσR1 was predominantly distributed in the fractions of cell membrane and cytoplasm,but not in those of *** whole-cell recordings in retinal slice preparations,we first characterized NMD A receptor-mediated currents of GCs.A robust inward current was induced from GCs with focal puff of 1 mM NMD A to the dendrites or with puff of 120 mM KCl onto the somata of associated bipolar cells in the absence of *** current could be completely blocked by D-Aβ5,a specific NMDA receptor *** further showed that theσR1 agonist SKF10047 or PRE-084 suppressed NMDA-induced currents in a dose-dependent manner from both ON and OFF type GCs and the effect could be reversed by theσR1 antagonist BD1047 or ***,activation ofσR1 could also suppress NMDA receptor-mediated ON and OFF light responses of *** results suggest that theσR1-mediated neuroprotective effects on GCs may be,at least in part, due to the suppression of NMDA receptors caused by activation ofσR1.

关键词： σR1 NMD A receptor ganglion cells retina

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肝泡状棘球蚴病的超声及病理表现

世界华人消化杂志 2008年第26期16卷 3001-3004页

作者：敬基刚李永忠庄华彭玉兰四川大学华西医院超声诊断科阿坝州人民医院超声科四川省马尔康县624000

目的:分析肝泡状棘球蚴病患者的临床、病理及超声图像特征.方法:回顾性分析2002-2007年我院经手术病理证实的肝泡状棘球蚴病患者15例的超声图像特征并分型.结果:15例肝泡状棘球蚴病单发12例,多发3例,共发现肿块20个;超声特征:多位于左肝... 详细信息

目的:分析肝泡状棘球蚴病患者的临床、病理及超声图像特征.方法:回顾性分析2002-2007年我院经手术病理证实的肝泡状棘球蚴病患者15例的超声图像特征并分型.结果:15例肝泡状棘球蚴病单发12例,多发3例,共发现肿块20个;超声特征:多位于左肝,大小多为5cm以上,形态多不规则,边界多清晰,内部回声多呈高回声、不均匀、无液化、无钙化,后方回声多衰减,无声晕、无内部血流多见,未见肝门及腹腔淋巴结肿大;根据声像图特征分为:实性肿块型(13个,65%)、肿块液化型(7个,35%)、肿块钙化型(8个,40%).结论:超声检查肝泡球蚴病超声影像具有特征性,是肝泡球蚴病重要的影像学检查方法.

关键词：泡状棘球蚴病肝脏超声

4H-SiC基半超结VDMOSFET单粒子效应加固研究

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电力电子技术 2017年第9期51卷 64-67页

作者：刘忠永蔡理刘保军刘小强空军工程大学理学院陕西西安710051 空军第一航空学院河南信阳464000

研究了"高K栅"介质HfO_2和电荷失配对4H-碳化硅(SiC)基半超结垂直双扩散金属氧化物半导体场效应晶体管(VDMOSFET)单粒子烧毁(SEB)和单粒子栅穿(SEGR)效应的影响,并给出了一种加固结构。研究结果表明,HfO_2介质的应用对器件SEB效应没有影... 详细信息

研究了"高K栅"介质HfO_2和电荷失配对4H-碳化硅(SiC)基半超结垂直双扩散金属氧化物半导体场效应晶体管(VDMOSFET)单粒子烧毁(SEB)和单粒子栅穿(SEGR)效应的影响,并给出了一种加固结构。研究结果表明,HfO_2介质的应用对器件SEB效应没有影响,但栅氧化层电场峰值降低了83%,对SEGR效应有加固作用。结合HfO_2介质层和增加沟道掺杂浓度两种方法的加固结构,在不影响器件阈值电压的同时,器件的SEB闽值电压为1 290 V,提高了28%;栅氧化层的电场峰值为2.2×10~6V/cm,降低了80%。当N柱区掺杂浓度大于P柱区时,器件的抗SEB能力有所增强,但N柱区掺杂浓度小于P柱区时,器件的抗SEB能力减弱。

关键词：垂直双扩散金属氧化物半导体效应管单粒子效应