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Multi-Objective Optimization of Aluminum Alloy Electric Bus Frame Connectors for Enhanced Durability

Computer Modeling in Engineering & Sciences 2024年第7期140卷 735-755页

作者： Wenjun Zhou Mingzhi Yang Qian peng yong peng Kui Wang Qiang Xiao Key Laboratory of Traffic Safety on Track Ministry of EducationSchool of Traffic&Transportation EngineeringCentral South UniversityChangsha410018China School of Mechanical and Automotive Engineering Xiamen University of TechnologyXiamen361024China

The widespread adoption of aluminumalloy electric buses,known for their energy efficiency and eco-friendliness,faces a challenge due to the aluminum frame’s susceptibility to deformation compared to steel.This issue is further exacerbated by the stringent requirements imposed by the flammability and explosiveness of batteries,necessitating robust frame protection.Our study aims to optimize the connectors of aluminum alloy bus frames,emphasizing durability,energy efficiency,and safety.This research delves into Multi-Objective Coordinated Optimization(MCO)techniques for lightweight design in aluminum alloy bus body connectors.Our goal is to enhance lightweighting,reinforce energy absorption,and improve deformation resistance in connector components.Three typical aluminum alloy connectors were selected and a design optimization platform was built for their MCO using a variety of software and methods.Firstly,through three-point bending experiments and finite element analysis on three types of connector components,we identified optimized design parameters based on deformation patterns.Then,employing Optimal Latin hypercube design(OLHD),parametric modeling,and neural network approximation,we developed high-precision approximate models for the design parameters of each connector component,targeting energy absorption,mass,and logarithmic strain.Lastly,utilizing the Archive-based Micro Genetic Algorithm(AMGA),Multi-Objective Particle Swarm Optimization(MOPSO),and Non-dominated SortingGenetic Algorithm(NSGA2),we explored optimized design solutions for these joint components.Subsequently,we simulated joint assembly buckling during bus rollover crash scenarios to verify and analyze the optimized solutions in three-point bending simulations.Each joint component showcased a remarkable 30%–40%mass reduction while boosting energy absorption.Our design optimization method exhibits high efficiency and costeffectiveness.Leveraging contemporary automation technology,the design optimization platform developed in this study is poised

关键词： Aluminum connectors three-point bending simulation parametric design model multi-objective collaborative optimization

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Mechanism of internal thermal runaway propagation in blade batteries

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Journal of Energy Chemistry 2024年第2期89卷 184-194,I0005页

作者： Xuning Feng Fangshu Zhang Wensheng Huang yong peng Chengshan Xu Minggao Ouyang School of Vehicle and Mobility Tsinghua UniversityBeijing 100084China

Blade batteries are extensively used in electric vehicles,but unavoidable thermal runaway is an inherent threat to their safe use.This study experimentally investigated the mechanism underlying thermal runaway propagation within a blade battery by using a nail to trigger thermal runaway and thermocouples to track its propagation inside a cell.The results showed that the internal thermal runaway could propagate for up to 272 s,which is comparable to that of a traditional battery module.The velocity of the thermal runaway propagation fluctuated between 1 and 8 mm s^(-1),depending on both the electrolyte content and high-temperature gas diffusion.In the early stages of thermal runaway,the electrolyte participated in the reaction,which intensified the thermal runaway and accelerated its propagation.As the battery temperature increased,the electrolyte evaporated,which attenuated the acceleration effect.Gas diffusion affected thermal runaway propagation through both heat transfer and mass transfer.The experimental results indicated that gas diffusion accelerated the velocity of thermal runaway propagation by 36.84%.We used a 1D mathematical model and confirmed that convective heat transfer induced by gas diffusion increased the velocity of thermal runaway propagation by 5.46%-17.06%.Finally,the temperature rate curve was analyzed,and a three-stage mechanism for internal thermal runaway propagation was proposed.In Stage I,convective heat transfer from electrolyte evaporation locally increased the temperature to 100℃.In Stage II,solid heat transfer locally increases the temperature to trigger thermal runaway.In StageⅢ,thermal runaway sharply increases the local temperature.The proposed mechanism sheds light on the internal thermal runaway propagation of blade batteries and offers valuable insights into safety considerations for future design.

关键词： Lithium-ion battery Blade battery Thermal runaway Internal thermal runaway propagation

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Identification of Motor Nuclei in the Medulla Oblongata of Carp for Biological Control

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Journal of Bionic Engineering 2024年第2期21卷 842-851页

作者： Yang Zhao yong peng Yudong Wen Lingjun Han Yanhong Yan Xueying Dong Hui Zhang Zheng Zhao Xiaoyue Liu School of Electrical Engineering Yanshan UniversityQinhuangdao066004China School of Mechanical Engineering Yanshan UniversityQinhuangdao066004China Key Laboratory of National Defense of Mechanical Structure and Material Science Under Extreme Conditions Yanshan UniversityQinhuangdao066004China Institute of Marine Science and Engineering Yanshan UniversityQinhuangdao066004China Shijiazhuang University Shijiazhuang050035China

Brain-controlled technology is the key technology in biological control,and the corresponding relationship between animal brain nuclei and motor behavior is the core.The purpose of this study was to explore the motor nuclei of the medulla oblongata in carp.The carps were subjected to electrical stimulation and chemical stimulation experiments,respectively,in the water-free state,and the effective chemical stimulation sites were injected with the pontamine sky blue solution.The brain tissue sections were obtained by paraffin tissue section technology and the neutral red staining method.By comparing the positions of the brain nuclei shown in earlier studies,the motor nerve nuclei in the medulla oblongata were identified.The brain electrode was implanted into the motor nucleus of the medulla oblongata,and the underwater control experiment and behavioral tests were carried out with different electrical stimulation parameters.The results showed that the abducens nucleus(NVI)was the motor nucleus that controls the ipsilateral steering,and the facial nucleus(NVII)was the motor nucleus that controls the forward movement.By adjusting the stimulation voltage and the stimulation pulse number,the carp can be stably controlled to achieve a left–right steering motion of 30°–180°and a forward motion of more than 80 cm/s.This study indicated that the quantitative control of the steering and forward behavior of the carp can be achieved by electrical stimulation of the NVI and NVII,which provided a certain experimental basis for the accurate control of the carp robot.

关键词： Biological control Carp Medulla oblongata motor nucleus Electrical stimulation technique Chemical stimulation technique

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Heterogeneous body compositions and all-cause mortality in acute coronary syndrome patients:a ten-year retrospective cohort study

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Journal of Geriatric Cardiology 2024年第5期21卷 534-541页

作者： Guang-Zhi LIAO Lin BAI Yu-Yang YE Xue-Feng CHEN Xin-Ru HU yong peng Department of Cardiology West China HospitalSichuan UniversityChengduSichuanChina

BACKGROUND The association of different body components,including lean mass and body fat,with the risk of death in acute coronary syndrome(ACS)patients are unclear.METHODS We enrolled adults diagnosed with ACS at our center between January 2011 and December 2012 and obtained fol-low-up outcomes via telephone questionnaires.We used restricted cubic splines(RCS)with the Cox proportional hazards model to analyze the associations between body mass index(BMI),predicted lean mass index(LMI),predicted body fat percentage(BF),and the value of LMI/BF with 10-year mortality.We also examined the secondary outcome of death during hospitalization.RESULTS During the maximum 10-year follow-up of 1398 patients,331 deaths(23.6%)occurred,and a U-shaped relationship was found between BMI and death risk(P_(nonlinearity)=0.03).After adjusting for age and history of diabetes,the overweight group(24≤BMI<28 kg/m^(2))had the lowest mortality(HR=0.53,95%CI:0.29-0.99).Predicted LMI and LMI/BF had an inverse linear relationship with a 10-year death risk(P_(nonlinearity)=0.24 and P_(nonlinearity)=0.38,respectively),while an increase in BF was associ-ated with increased mortality(P_(nonlinearity)=0.64).During hospitalization,31 deaths(2.2%)were recorded,and the associations of the indicators with in-hospital mortality were consistent with the long-term outcome analyses.CONCLUSION Our study provides new insight into the“obesity paradox”in ACS patients,highlighting the importance of considering body composition heterogeneity.Predicted LMI and BF may serve as useful tools for assessing nutritional status and predicting the prognosis of ACS,based on their linear associations with all-cause mortality.

关键词： patients mortality coronary

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Role of autoreactive Tc17 cells in the pathogenesis of experimental autoimmune encephalomyelitis

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Neuroprotection 2024年第1期2卷 49-59页

作者： yong peng Xiuli Zhang Yandan Tang Shunqing He Guilan Rao Quan Chen Yahui Xue Hong Jin Shu Liu Ziyang Zhou Yun Xiang Department of Neurology Affliated First Hospitalof HunanTraditional Chinese Medical CollegeZhuzhouHunanChina Department of Neurology The Third Affiliated Hospital of Hunan University of Chinese MedicineZhuzhouHunanChina Science and Technology Innovation Center HunanUniversityof ChineseMedicineChangshaHunanChina

Background:The pathogenesis of multiple sclerosis(MS)and experimental autoimmune encephalomyelitis(EAE-an animal model of MS)is primarily mediated by T cells.However,recent studies have only focused on interleukin(IL)-17-secreting CD4^(+)T-helper cells,also known as Th17 cells.This study aimed to compare Th17 cells and IL-17-secreting CD8^(+)T-cytotoxic cells(Tc17)in the context of MS/EAE.Methods:Female C57BL/6 mice were immunized with myelin oligodendrocyte glycoprotein peptides 35-55(MOG35-55),pertussis toxin,and complete Freund's adjuvant to establish the EAE animal model.T cells were isolated from the spleen(12-14 days postimmunization).CD4^(+)and CD8^(+)T cells were purified using isolation kit and then differentiated into Th17 and Tc17,respectively,using MOG35-55 and IL-23.The secretion levels of interferon-(IFN-γ)and IL-17 were measured via enzyme-linked immunosorbent assay using cultured CD4^(+)and CD8^(+)T cell supernatants.The pathogenicity of Tc17 and Th17 cells was assessed through adoptive transfer(tEAE),with the clinical course assessed using an EAE score(0-5).Hematoxylin and eosin as well as Luxol fast blue staining were used to examine the spinal cord.Purified CD8^(+)CD3^(+)and CD4^(+)CD3^(+)cells differentiated into Tc17 and Th17 cells,respectively,were stimulated with MOG35-55 peptide for proliferation assays.Results:The results showed that Tc17 cells(15,951±19855VS.55,709±4196cpm;p<0.050)exhibited a weaker response to highest dose(20μg/mL)MOG35-55 than Th17 cells.However,this response was not dependent on Th17 cells.After the 48h stimulation,at the highest dose(20μg/mL)of MOG35-55.Tc17 cells secreted lower levels of IFN-(280.00±15.00vs.556.67±15.28pg/mL,p<0.050)and IL-17(102.67±5.86 pg/mL vs.288.33±12.58 pg/mL;p<0.050)than Th17 cells.Similar patterns were observed for IFN-γsecretion at 96 and 144h.Furthermore,Tc17 cell-induced tEAE mice exhibited similar EAE scores to Th17 cell-induced tEAE mice and also showed similar inflammation and demyelination.Conclusion:The degree of pathogenicity of Tc1

关键词： CD8^(+)T cells experimental autoimmune myelitis IFN-y IL-17 multiple sclerosis Tc17 cells

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A tRF oligomerizes Nucleolin to stabilize metastasis-favoring transcripts

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Science China(Life Sciences) 2023年第3期66卷 646-648页

作者： Jiawei Guo yong peng Laboratory of Molecular Oncology Frontiers Science Center for Disease-related Molecular Network State Key Laboratory of Biotherapy and Cancer Center West China Hospital Sichuan University

Apart from bringing amino acids to ribosomes for protein biogenesis,transfer RNA(t RNA)can be cleaved into small non-coding RNAs,named as t RFs or ts RNAs.These small RNA fragments were firstly thought as random degradation products of t RNAs until the induction of certain t RFs were observed in specific stress conditions(Li et al.,2008).

关键词： metastasis bringing

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Tc17 cells inautoimmune diseases

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Chinese Medical Journal 2022年第18期135卷 2167-2177页

作者： yong peng Xiang Deng Qiuming Zeng Yandan Tang Department of Neurology Affliated First Hospital of Hunan Traditional Chinese Medical CllegeZhuzhouHunan 412000China Department of Neurology Xiangya HospitalCentral South UniversityChangshaHunan 410008China

Multiple sclerosis(MS)and experimental autoimmune encephalomyelitis(EAE),a pathologically similar disease used to model MS in rodents,are typical CD4^(^(+))T cell-dominated autoimmune diseases.CD4^(+)interleukin(IL)17^(+)T cells(Th17 cells)have been well studied and have shown that they play a critical role in the pathogenesis of MS/EAE.However,studies have suggested that CD8^(+)IL17^(+)T cells(Tc17 cells)have a similar phenotype and cytokine and transcription factor profiles to those of Th17 cells and have been found to be crucial in the pathogenesis of autoimmune diseases,including MS/EAE,psoriasis,type I diabetes,rheumatoid arthritis,and systemic lupus erythematosus.However,the evidence for this is indirect and insufficient.Therefore,we searched for related publications and attempted to summarize the current knowledge on the role of Tc17 cells in the pathogenesis of MS/EAE,as well as in the pathogenesis of other autoimmune diseases,and to find out whether Tc17 cells or Th17 cells play a more critical role in autoimmune disease,especially in MS and EAE pathogenesis,or whether the interaction between these two cell types plays a critical role in the development of the disease.

关键词： Tc17 Autoimmune diseases Multiple sclerosis Experimental autoimmune encephalomyelitis Retinoic acid receptorrelated orphan receptor gamma Th17

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Research on low carbon emission optimization operation technology of natural gas pipeline under multi-energy structure

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Petroleum Science 2022年第6期19卷 3046-3058页

作者： En-Bin Liu yong peng Shan-Bi peng Bin Yu Qi-Kun Chen Petroleum Engineering School Southwest Petroleum UniversityChengdu610500China School of Civil Engineering and Geomatics Southwest Petroleum UniversityChengdu610500China China Petroleum Pipeline Engineering Corporation Hebei065000China School of Engineering Cardiff UniversityCardiffCF243AAUK

In order to reduce the carbon emissions of natural gas pipelines,based on the background of different energy structures,this paper proposes a general low carbon and low consumption operation model of natural gas pipelines,which is used to fine calculate the carbon emissions and energy consumption of natural gas pipeline.In this paper,an improved particle swarm optimization(NHPSO-JTVAC)algorithm is used to solve the model and the optimal scheduling scheme is given.Taking a parallel pipeline located in western China as an example,the case is analyzed.The results show that after optimization,under the existing energy types,the pipeline system can reduce 31.14%of carbon emissions,and after introducing part of new energy,the pipeline system can reduce 34.02%of carbon emissions,but the energy consumption has increased.

关键词： Natural gas Pipeline optimization NHPSO-JTVAC algorithm Carbon emission New energy

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Structural optimization design of a bolster based on a simulation-driven design

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Transportation Safety and Environment 2023年第4期5卷 91-99页

作者： Xinkang Li Fei peng Zeyun Yang yong peng Jiahao Zhou Technical Research Department CRRC Industrial Research Institute(Qingdao)Co.Ltd.Qingdao 266109ShandongChina Key Laboratory of Traffic Safety on Track of Ministry of Education School of Traffic and Transportation EngineeringCentral South UniversityChangsha 410075HunanChina

A simulation-driven design method which uses multiple optimization methods can effectively promote innovative structural design tion analysis can enormously improve the efficiency of modelling and solving.This study establishes a general workflow of structural and reduce the product development cycle.Meanwhile,the sub-model technology which has more detailed simulation and optimizaoptimization for a stainless-steel metro bolster by combining the simulation-driven design method and sub-model technology.In the sub-model definition phase,the end underframe sub-model which contains the bolster is obtained based on the whole car body finite element(FE)model,and the effectiveness of the end underframe sub-model is also proved.In the conceptual design phase,the is determined according to manufacturing processes and design experiences.In the detailed design phase,the thickness of each topology path inside the bolster is obtained by the topology method and the optimized structure of the inner ribs inside the bolster part of the bolster is determined by size optimization.The simulation analyses indicate that the requirements of static strength and can be decreased by 17.79% compared with the original bolster structure,which means that not only the lightweight design goal fatigue strength are fulfilled by the optimized bolster structure.Besides,the weight can be reduced by 11.18% and the weld length is achicved.but also the welding auantity and manufacturing difficulty are geatly reduced.The results show the effectiveness of the simulation-driven design method based on the sub-model technology in the structural optimization for key parts of rail transit vehicles.

关键词： simulation driven design sub-model topology optimization size optimization stainless-steel metro bolster

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Modeling and Simulation of Cooperative Exploration Strategies in Unknown Environments

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Complex System Modeling and Simulation 2023年第4期3卷 343-356页

作者： yong peng Yue Hu Chuan Ai College of Systems Engineering National University of Defense TechnologyChangsha 410073China

Cooperative spatial exploration in initially unknown surroundings is a common embodied task in various applications and requires satisfactory coordination among the agents.Unlike many other research questions,there is a lack of simulation platforms for the cooperative exploration problem to perform and statistically evaluate different methods before they are deployed in practical scenarios.To this end,this paper designs a simulation framework to run different models,which features efficient event scheduling and data sharing.On top of such a framework,we propose and implement two different cooperative exploration strategies,i.e.,the synchronous and asynchronous ones.While the coordination in the former approach is conducted after gathering the perceptive information from all agents in each round,the latter enables an ad-hoc coordination.Accordingly,they exploit different principles for assigning target points for the agents.Extensive experiments on different types of environments and settings not only validate the scheduling efficiency of our simulation engine,but also demonstrate the respective advantages of the two strategies on different metrics.

关键词： modeling and simulation event scheduling cooperative exploration synchronous strategy asynchronous strategy

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