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A tRF oligomerizes Nucleolin to stabilize metastasis-favoring transcripts

A tRF oligomerizes Nucleolin to stabilize metastasis-favoring transcripts

作     者:Jiawei Guo Yong Peng 

作者机构:Laboratory of Molecular Oncology Frontiers Science Center for Disease-related Molecular Network State Key Laboratory of Biotherapy and Cancer Center West China Hospital Sichuan University 

出 版 物:《Science China(Life Sciences)》 (中国科学(生命科学英文版))

年 卷 期:2023年第66卷第3期

页      面:646-648页

核心收录:

学科分类:0710[理学-生物学] 07[理学] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

基  金:supported by the National Natural Science Foundation of China(82273168) the Science and Technology Foundation of Sichuan Province,China(2022YFS0046) the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYGD20008) 

主  题:metastasis bringing 

摘      要:Apart from bringing amino acids to ribosomes for protein biogenesis,transfer RNA(t RNA)can be cleaved into small non-coding RNAs,named as t RFs or ts *** small RNA fragments were firstly thought as random degradation products of t RNAs until the induction of certain t RFs were observed in specific stress conditions(Li et al.,2008).

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