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On the Reform of ESP Curriculum for New Medicine Discipline

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Cultural and Religious Studies 2024年第9期12卷 575-579页

作者： ZHANG Yan BAI Wenjie chen yingzhu LIAN Yujie Guangxi University of Chinese Medicine NanningChina

This paper discusses the reform of ESP(English for special purpose)curriculum in Chinese medicine universities for new medicine *** reconstruction of ESP curriculum and evaluation system can better meet different students’needs,broaden their horizons,and cultivate compound talents of Chinese medicine with more competitiveness and international vision.

关键词： ESP curriculum evaluation system Chinese medicine

产教融合背景下广西民办高校教师教学能力现状及提升路径

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创新创业理论研究与实践 2024年第13期7卷 121-123页

作者：陈盈竹广西外国语学院广西南宁530222

教师的教学能力是决定人才培养质量的核心要素,在广西地区的民办高校中,教师实践教学水平受到诸多因素的制约,影响了复合型人才培养。为了构建一支既能够传授理论知识,又具备丰富实践经验,可培育适应未来社会需求的复合型人才的师资队伍... 详细信息

教师的教学能力是决定人才培养质量的核心要素,在广西地区的民办高校中,教师实践教学水平受到诸多因素的制约,影响了复合型人才培养。为了构建一支既能够传授理论知识,又具备丰富实践经验,可培育适应未来社会需求的复合型人才的师资队伍,针对性提升高校教师的综合能力,该文在产教融合视域下,深入分析广西民办高校教师教学能力提升的路径,以期为提高广西民办高校的师资建设水平提供相关参考。

关键词：产教融合民办高校师资队伍教学能力现状路径

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《黄帝内经》“五音”的英译考辨

中国科技翻译 2024年第2期37卷 17-20页

作者：袁卓喜司徒旋子陈滢竹广西大学外国语学院南宁市530004 广西中医药大学南宁市530001

历代医家对“五音”的注解较为零散,对“五音”之音为何也鲜有明确的界定,这给对外翻译中医“五音”相关术语带来一定困难。本文以经文考释和训字为视角,对四个《黄帝内经》英译本中“五音”术语的译法进行深入考辨,认为以tone译“五音... 详细信息

历代医家对“五音”的注解较为零散,对“五音”之音为何也鲜有明确的界定,这给对外翻译中医“五音”相关术语带来一定困难。本文以经文考释和训字为视角,对四个《黄帝内经》英译本中“五音”术语的译法进行深入考辨,认为以tone译“五音”之音更符合五音疗疾中“音”的所指。中医“五音”英译不仅要忠实传译“五音”之音的所指,还需向目标语读者准确诠释“五音疗疾”的医理。

关键词：黄帝内经五音英译考辨

基于生态系统理论的帕金森病患者及照护者居家康复运动影响因素的质性研究

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护理学杂志 2024年第14期39卷 21-26页

作者：冒鑫娥王鑫李亚楠郭晓娟韩晶陈应柱江苏省苏北人民医院老年医学科江苏扬州225001 江苏省苏北人民医院健康管理中心江苏扬州225001

目的探讨帕金森病患者及其照护者对居家康复锻炼的真实体验,深入挖掘居家康复的影响因素,为提高帕金森病患者居家康复质量提供参考依据。方法采用描述性质性研究,选取16对居家康复锻炼的帕金森病患者及其主要照护者进行半结构式访谈,基... 详细信息

目的探讨帕金森病患者及其照护者对居家康复锻炼的真实体验,深入挖掘居家康复的影响因素,为提高帕金森病患者居家康复质量提供参考依据。方法采用描述性质性研究,选取16对居家康复锻炼的帕金森病患者及其主要照护者进行半结构式访谈,基于Bronfenbrenner生态系统理论模型、利用主题分析法和配对分析法对访谈资料进行分析和提炼主题。结果提炼出微系统——帕金森病患者个体特质(疾病现状与进展、心理弹性与应对方式、创伤后成长、运动自我效能与动机)、中系统——家庭抗逆力系统(主要照护者微系统特质、家庭信念系统、家庭组织模式、家庭沟通过程)、外系统——相关社会领域及宏系统——文化环境4个主题。结论帕金森病患者居家康复运动受多种因素的影响,患者及其家庭应充分激发个体主观能动性、重视主要照护者照护功能、调动家庭抗逆力实现家庭复原、合理利用社会资源,医疗教育等社会领域应充分聚焦专科性发展、建立支持系统协同实现帕金森病患者居家康复。

关键词：帕金森病居家康复运动锻炼生态系统家庭参与影响因素质性研究

Genetic and antigenic characterization of recombinant nucleocapsid proteins derived from canine coronavirus and canine respiratory coronavirus in China

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Science China(Life Sciences) 2016年第6期59卷 615-621页

作者： Shuai Lu yingzhu chen Kun Qin Jianfang Zhou Yongliang Lou Wenjie Tan Institute of Medical Virology Wenzhou Medical University National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention

To characterize the antigenicity of nucleocapsid proteins(NP) derived from canine coronavirus(CCo V) and canine respiratory coronavirus(CRCo V) in China, the N genes of CCo V(CCo V-BJ70) and CRCo V(CRCo V-BJ202) were cloned from swabs obtained from diseased pet dogs in Beijing and then sequenced. The recombinant NPs(r NPs) were expressed in Escherichia coli and purified by nickel-affinity column and size exclusion chromatography. Sequencing data indicated that the N genes of CCo V-BJ70 and CRCo V-BJ202 belonging to two distinctly different groups were relatively conserved within each subgroup. Sodium dodecyl sulfate polyacrylamide gel electrophoresis(SDS-PAGE) results showed that r NPs of CCo V and CRCo V were expressed efficiently and isolated with a final purity of over 95%. Western blot analysis revealed the r NP from CRCo V could cross-react with mice antisera against human coronavirus(HCo V-229 E, NL63, OC43, HKU1), while r NP of CCo V had cross-reactivity with only anti-sera against viruses belonging to the same group(HCo V-229 E and NL63). In summary, CCo V and CRCo V r NPs were successfully expressed in E. coli and showed antigenic cross-reactivity with antisera raised against human coronaviruses. These findings indicate that further serologic studies on coronavirus infections at the animal-human interface are needed.

关键词： canine coronavirus canine respiratory coronavirus nucleocapsid protein expression cross-reactivity

Modulation of dynamic aggregation in fluorogenic SNAP-tag probes for long-term super-resolution imaging

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聚集体(英文)

聚集体(英文) 2023年第2期4卷 173-182页

作者： Qinglong Qiao Wenjuan Liu Weijie Chi Jie chen Wei Zhou Ning Xu Jin Li Xiangning Fang Yi Tao Yinchan Zhang yingzhu chen Lu Miao Xiaogang Liu Zhaochao Xu CAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalianChina University of Chinese Academy of Sciences BeijingChina Fluorescence Research Group Singapore University of Technology and DesignSingaporeSingapore

The combination of super-resolution microscopy and synthetic fluorescence probes has emerged as a universal tool to monitor dynamic biological events at the nanometer ***,the limited site-specificity and fluorogenicity of synthetic fluorescent probes make it still difficult to realize long-term super-resolution ***,we introduce a dynamic aggregation mediated SNAP-tag fluorogenic probe,BGAN-Aze,which can specifically bind to various SNAP-tag fusion proteins with 41-fold fluorescence *** equilibrium between the non-fluorescent aggregate/dimer(A–D)and the fluorescent monomer(M)of BGAN-Aze acts as an effective method to reduce the fluorescence background and endow BGAN-Aze with the capability of conducting washing-free super-resolution imaging of various intracellular and extracellular *** this probe,we monitored multiple dynamic biological events,such as MMC,mitophagy,the fusion of nucleolus,and the growth and contact of *** expect that BGAN-Aze will become a widely used SNAP-tag for super-resolution imaging of dynamic biological events and the A-D-M equilibrium can be a general strategy for designing fluorogenic probes.

关键词： aggregation dimer fluorogenic SNAP-tag super-resolution imaging

不同免疫状态患者念珠菌血症的实验室检测特征分析

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中国感染与化疗杂志 2020年第1期20卷 49-54页

作者：陈盈竹夏云重庆医科大学附属第一医院检验科重庆400016

目的探讨不同免疫状态患者念珠菌血症的病原菌分布及药敏、血清标志物等实验室检验指标的差异。方法回顾性收集分析2016年1月-2018年12月重庆医科大学附属第一医院念珠菌血症患者的临床和实验室相关资料。结果103例患者纳入分析,免疫抑... 详细信息

目的探讨不同免疫状态患者念珠菌血症的病原菌分布及药敏、血清标志物等实验室检验指标的差异。方法回顾性收集分析2016年1月-2018年12月重庆医科大学附属第一医院念珠菌血症患者的临床和实验室相关资料。结果103例患者纳入分析,免疫抑制组58例,非免疫抑制组45例。非免疫抑制组接受体内导管置入和完全肠外营养的比例明显高于免疫抑制组;微生物学特征显示免疫抑制组的热带念珠菌分离率明显高于非免疫抑制组,非免疫抑制组的近平滑念珠菌分离率明显高于免疫抑制组;对三唑类抗真菌药物的整体敏感率免疫抑制组低于非免疫抑制组,耐药菌主要为热带念珠菌;发生念珠菌血症时,两组患者血清降钙素原和C反应蛋白值均高于参考值范围;免疫抑制组患者血清(1,3)-β-D葡聚糖(BDG)阴性率明显高于非免疫抑制组。结论根据患者不同免疫状态,更好识别不同患者的病原菌分布特点,有助于临床医师选择更合理的抗真菌药物。然而,血清BDG检测不能早期识别所有念珠菌血症患者,特别是免疫抑制患者,需要结合降钙素原和C反应蛋白值综合判断。

关键词：念珠菌免疫抑制非免疫抑制血流感染

Protective and Indicating Effect of Indirect Bilirubin in Intracranial or Extracranial Artery Atherosclerotic Stenosis Progresses

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International Journal of Clinical Medicine 2015年第7期6卷 512-519页

作者： yingzhu chen Xianxian Zhang Lingling Zhang Rongyin Qin Kangping Song Lu Xiao Department of Neurology Clinical Medical College Yangzhou University Yangzhou China Department of Neurology Yancheng Third People’s Hospital Yancheng China

Background: Bilirubin is the metabolic end-product of heme degradation by heme oxy-genase (HO), which has recently been shown to act as an antioxidant which can protect against atherosclerosis. This study explored the relationship between serum bilirubin levels and different degrees of atherosclerotic stenosis in intracranial or extracranial arteries. Methods: The study included 189 patients undergoing digital subtraction angiography (DSA) diagnosed as being normal or having been confirmed as atherosc lerotic stenosis in the intracranial or extracranial arteries. The patients were allocated to normal, mild (Results: Indirect bilirubin (Ibil) concentrations increased in parallel with the increasing severity of atherosclerotic stenosis in the intracranial or extracranial arteries, but decreased in patients with occluded cranial vessels. Multivariate analysis showed that Ibil levels were significantly higher in patients with severe stenosis group than in those with mild stenosis (OR, 1.464;95% CI, 1.050 - 2.042;P = 0.024). However, Ibil levels were significantly lower in patients with occlusion than in those with severe stenosis (OR, 0.790;95% CI, 0.684 - 0.913;P = 0.001). Conclusions: Ibil appears to have a protective effect against the development of atherosclerotic stenosis in intracranial or extracranial arteries. The biosynthesis of Ibil increases with stenosis progresses but decreases once occlusion occurs.

关键词： Indirect Bilirubin Atherosclerotic Stenosis Intracranial Arteries Extracranial Arteries

类型学视野下的选择性疑问代词研究——以中国境内少数民族语言为例

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民族语文 2020年第2期 75-84页

作者：陈滢竹乐明广西中医药大学南宁530200 浙江大学杭州310058

本文考察发现59种中国境内少数民族语言或方言具有选择性疑问代词。与普通疑问代词不同的是,选择性疑问代词表示在“有定的范围,不定的对象”中进行选择的语义,这符合世界上大多数语言的共性。不同语言的选择性疑问代词具有一定的共性... 详细信息

本文考察发现59种中国境内少数民族语言或方言具有选择性疑问代词。与普通疑问代词不同的是,选择性疑问代词表示在“有定的范围,不定的对象”中进行选择的语义,这符合世界上大多数语言的共性。不同语言的选择性疑问代词具有一定的共性和差异。由于需要表达“有定性”,有的少数民族语言采用词形和形态方式区分选择性疑问代词与普通疑问代词。此外,有些语言的选择性疑问代词通过标记“数”和“格”体现形态变化。句法上,本文考察的少数民族语言或方言暂没有发现采用语序移位的方式,均保持原位;部分语言的选择性疑问代词可以作论元。

关键词：选择性疑问代词少数民族语言有定性