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Role of retained austenite in advanced high-strength steel:ductility and toughness

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Journal of Iron and Steel Research International 2024年第9期31卷 2079-2089页

作者： Vung Lam Nuam Hao Zhang ying-chun wang Zhi-ping Xiong National Key Laboratory of Science and Technology on Materials under Shock and Impact School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing100081China Tangshan Key Laboratory of High-Performance Metals and Ceramics Tangshan Research Institute BITTangshan063000HebeiChina

Enhancing the ductility and toughness of advanced high-strength steels is essential for the wide range of promising *** retained austenite(RA)is a key phase due to the austenite-to-martensite transformation and its transformation-induced plasticity *** is commonly accepted that slow RA-to-martensite transformation is beneficial to ductility;therefore,the RA fraction and stability should be carefully *** RA stability is related to its morphology,size,carbon content,neighboring phase and ***,these factors are *** is noteworthy that the influence of RA on ductility and fracture toughness is not consistent because of their difference in stress *** is no clear relationship between fracture toughness and tensile ***,it is important to understand the role of RA in *** toughness is enhanced during the RA-to-martensite transformation,while the fracture toughness is decreased due to the formation of fresh and brittle *** a result,the findings regarding to the effect of RA on fracture toughness are *** investigations should be conducted in order to fully understand the effects of RA on ductility and fracture toughness,which can optimize the combination of ductility and toughness in AHSSs.

关键词： Retained austenite Ductility Toughness TRIP effect Steel

Microstructure and mechanical properties of a Cr-Ni-W-Mo steel processedthermo-mechanical controlled processing

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Journal of Iron and Steel Research International 2021年第6期28卷 713-721页

作者： Jia-xin Liang ying-chun wang Xing-wang Cheng Zhuang Li Jin-ke Du Shu-kui Li School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China National Key Laboratory of Science and Technology on Materials Under Shock and Impact Beijing 100081China

Experiments were conducted to evaluate the microstructure and tensile properties of a medium carbon Cr-Ni-W-Mo steel processedthermo-mechanical controlled processing(TMCP)with cooling at different conditions in water,oil,air or lime followedlow *** to normal heat-treatment processing,TMCP with water-cooling after deformation enhances the yield strength and tensile strength of the steelabout 323 MPa and about 251 MPa,respectively,due to higher dislocation strengthening and grain boundary ***,it increases the elongation by ;about 1.76%attributed to the increase in volume percentage of the retained austenite and the refined laths of tempered *** the cooling rate after deformation during TMCP leads to a decrease in the *** results the coupling effectsthe reduction in dislocation density and volume fraction of tempered martensite together with the coarseness in martensite ***,cooling rate decreasing has less influences on ductility becathe improved elongation the increase in the volume fractions of both retained austenite and lower bainite together with dislocation density decreasing is compensatedthe reduced elongation coarsened grains.

关键词： Thermo-mechanical controlled processing Ultra-high strength steel Microstructure Bainite Tensile property

Trace amount of single-atom palladium-catalyzed selective hydrosilylation of allenes

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Nano Research 2022年第8期15卷 7091-7098页

作者： Li-Ping Pang Xin-Yu Li Shi-Cheng Ren Hong-Min Lin ying-chun wang ying-Ming Pan Hai-Tao Tang State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources School of Chemistry and Pharmaceutical Sciences of Guangxi Normal UniversityGuilin 541004China College of Chemistry and Chemical Engineering Jishou UniversityJishou 416000China

Using fewer catalysts to promote the chemical conversion of more substrates is the dream synthesis pursued by synthetic *** highly selective reactions using trace amounts(100:1).The catalyst could be recycled numerous times in a continuous flow system without reductions in activity and *** work demonstrated the application prospect of the SAC in the synthesis of complex organic compounds and trace amount catalysis,which can lay the foundation for its large-scale and industrialized application in drug synthesis and other fields.

关键词： trace catalysis single-atom catalysts hydrosilylation allenes

Role of shear wave elastography in the evaluation of the treatment and prognosis of supraspinatus tendinitis

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World Journal of Clinical Cases 2020年第14期8卷 2977-2987页

作者： Jie Zhou De-Bin Yang Jing wang Hui-Zhang Li ying-chun wang Department of Ultrasonic Imaging Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health SciencesShanghai 201800China Department of Orthopaedics Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health SciencesShanghai 201800China

BACKGROUND Supraspinatus tendinitis recurs easily after *** of the main reasons is the lack of objective tools for the efficacy *** wave elastography(SWE)can quantitatively analyze the tissue elasticity of region of interest by measuring the Young’s modulus(YM)*** To explore the role of SWE in the efficacy and prognostic evaluation of supraspinatus *** Eighty-seven patients with supraspinatus tendinitis treated in Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health Sciences were *** 30 healthy volunteers were enrolled as the control *** visual analogue scale(VAS)and Constant-Murley Score(CMS)were recorded before *** participants were scanned by SWE scan,and the YM value of the region of interest were *** correlation analysis was performed on YM values with VAS and *** repeated measures analysis of variance was used to calculate the changing trend of VAS,CMS and SWE under different treatment *** treatment,the patients were further grouped based on who achieved significantly effective and curative *** patients in the continued treatment group continued to receive treatment according to the YM value,and the remaining patients who stopped receiving treatment were included in the stopped treatment *** patients were followed up for 1 year,and the difference in recurrence rates between the continued treatment group and the stopped treatment group were *** The SWE images of supraspinatus muscle in healthy volunteers were mainly blue,while those of patients with supraspinatus tendinitis showed regional red and green *** average YM value of the supraspinatus muscle in healthy volunteers was 26.12±4.03 *** average YM value of patients with supraspinatus muscle was greater than that of healthy volunteers(average YM=60.61±11.53 kPa,t=26.344,P<0.001).The YM value was positively correlated with VAS(r

关键词： Supraspinatus tendinitis Shear wave elastography Young’s modulus value Visual analog score Constant-Murley score Recurrence

Effects of SAHA on proliferation and apoptosis of hepatocellular carcinoma cells and hepatitis B virus replication

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World Journal of Gastroenterology 2013年第31期19卷 5159-5164页

作者： ying-chun wang Xu Yang Lan-Hua Xing Wei-Zong Kong Department of Gastroenterology Affiliated Zhongshan Hospital of Dalian University

AIM: To investigate the effects of suberoylanilide hydroxamic acid(SAHA) on proliferation and apoptosis of a human hepatocellular carcinoma cell line(HepG2.2.15) and hepatitis B virus(HBV) ***: HepG2.2.15 cells were treated with different concentrations of *** morphology was examined by confocal laser scanning microscopy,and cell proliferation was determined using a MTT colorimetric *** cytometry was used to detect apoptosis and determine cell cycle phase,while hepatitis B surface antigen and hepatitis B e antigen content were measured using *** transcription polymerase chain reaction was performed to measure HBV DNA in cell ***: Cell proliferation rates were significantly reduced by the addition of *** inhibitory effect of SAHA on cell proliferation was both time-and *** 24 h of treatment with SAHA,the early cell apoptotic rate increased from 3.25% to 21.02%(P = 0.041).The proportion of G0 /G1 phase cells increased from 50.3% to 65.3%(P = 0.039),while that of S phase cells decreased from 34.9% to 20.6%(P = 0.049).After 48 h of treatment,hepatitis B surface antigen and hepatitis B e antigen content increased from 12.33 ± 0.62 to 25.42 ± 2.67(P = 0.020) and 28.92 ± 1.24 to 50.48 ± 1.85(P = 0.026),***,HBV DNA content increased from 4.54 ± 0.46 to 8.34 ± 0.59(P = 0.029).CONCLUSION: SAHA inhibits HepG2.2.15 cell proliferation,promotes apoptosis,and stimulates HBV *** combination with anti-HBV drugs,SAHA may potentially be used cautiously for treatment of hepatocellular carcinoma.

关键词： Human hepatocellular carcinoma HepG2.2.15 cells Suberoylanilide hydroxamic acid Hepatitis B virus

Efficacy ofβ2-adrenergic receptor agonist combined with corticosteroid in the treatment of children with cough variant asthma

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World Journal of Clinical Cases 2023年第31期11卷 7610-7618页

作者： Jun-Yi Cao ying-chun wang Xiao-Xia Deng Department of Pediatrics The First People's Hospital of Jiangxia DistrictWuhan 430200Hubei ProvinceChina Department of Pediatric Respiratory Maternal and Child Health Hospital of Hubei ProvinceTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430070Hubei ProvinceChina

BACKGROUND Cough variant asthma(CVA)is one of the most common respiratory diseases in children,which has a serious impact on the quality of life and daily activities of *** severe CVA,immunomodulatory drugs are *** To evaluate the efficacy of salmeterol combined with budesonide in the treatment of pediatric *** 130 children with CVA from January 2020 to December 2022 were prospectively selected and randomly divided into an observation group(salmeterol combined with budesonide)and a control group(budesonide combined with a placebo).Compare the clinical efficacy of two groups before and after *** evaluation parameters include cough frequency score,nocturnal cough arousal,and lung function *** inflammatory markers,immune function markers and airway anatomical indicators were also *** After the intervention,the total effective rate of the observation group was significantly higher than that of the control group,and the cough frequency score and the night cough wake rate of the observation group were lower than that of the control group,with a statistically significant *** addition,the changes of lung function indicators,serum markers and immune function markers in the observation group were better than those in the control *** The clinical efficacy of salmeterol combined with Budesonide in the treatment of CVA is better than that of Budesonide alone.

关键词： Salmeterol Budesonide Cough variant asthma Pediatrics Efficacy analysis

Effects of pulse magneto-oscillation on GCr15 bearing steel continuous casting billet

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Journal of Iron and Steel Research International 2022年第1期29卷 144-150页

作者： Yan-jie Liu Guo-dong Xu ying-chun wang Hong-gang Zhong Li-juan Li Biao wang Qi-jie Zhai Materials Genome Institute Shanghai UniversityShanghai 200444China Center for Advanced Solidification Technology Shanghai UniversityShanghai 200444China Research Institute China Baowu Steel Group CorporationShanghai 200431China Steel Plant China Baowu Steel Group CorporationShanghai 200431China

Pulse magneto-oscillation(PMO)added during solidification could affect the solidification structure and macrosegregation.A modified thermal simulation equipment was applied to prepare GCr15 bearing steel continuous casting billets with different PMO peak ***,metallographic analysis,component analysis and numerical simulation were adopted to study the influence of PMO peak current and its *** sample with 150 K_(I)A PMO peak current treatment has little difference with the samples without PMO treatment on solidification structure and *** the peak currents are 250 and 350 K_(I)A,the columnar zone increases and macrosegregation *** 450 K_(I)A peak current is selected,the equiaxed grain ratio is enlarged,and the dendritic grains are refined,and the macrosegregation of C,Cr,Si and Mn is decreased *** analyzing,different convections induced by PMO with various peak currents are the key factor to change the solidification structure and macrosegregation.

关键词： Bearing steel Numerical simulation Thermal simulation Pulse magneto-oscillation

Value of superb micro-vascular imaging in predicting ischemic stroke in patients with carotid atherosclerotic plaques

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World Journal of Clinical Cases 2019年第7期7卷 839-848页

作者： De-Bin Yang Jie Zhou Lan Feng Rong Xu ying-chun wang Department of Ultrasonic Imaging Jiading District Central Hospital Affiliated Shanghai University of Medicine & Health Sciences

BACKGROUND Unstable carotid atherosclerotic plaques are prone to cause ischemic ***-enhanced ultrasound(CEUS) is the primary method of assessing plaque stability, but CEUS cannot be a method for screening for unstable plaque. The emergence of superb micro-vascular imaging(SMI) offers the possibility of clinically screening for unstable plaque AIM To investigate the value of SMI in predicting ischemic stroke in patients with carotid atherosclerotic *** Patients with carotid atherosclerotic plaques(luminal stenosis of 50%-70%) were enrolled into the present study. All patients received conservative *** patient's clinical baseline data, serological data, CEUS and SMI data were analyzed. All patients underwent a 3-year follow-up. The follow-up endpoint was the occurrence of ischemic stroke and patients were divided into stroke group and non-stroke group according to whether the prognosis occurred or ***, the difference in clinical data was compared, the correlation of SMI and CEUS was analyzed, and multiple Cox regression and receiver operating characteristic curve were applied to investigate the value of SMI and CEUS in predicting cerebral arterial thrombosis in three *** In this study, 43 patients were enrolled in the stroke group and 82 patients were enrolled in the non-stroke group. Cox regression revealed that SMI level(P =0.013) and enhancement intensity(P = 0.032) were the independent factors influencing ischemic stroke. There was a positive correlation between SMI level and enhancement intensity(r = 0.737, P = 0.000). The area under curve of SMI level predicting ischemic stroke was 0.878. The best diagnostic point was ≥ level Ⅱ, and its sensitivity and specificity was 86.05% and 79.27%. The area under curve of enhancement intensity predicting ischemic stroke was 0.890. The best diagnostic point was 9.92 db, and its sensitivity and specificity was 88.37% and89.02%. As the SMI level gradually increased, the

关键词： Superb micro-vascular imaging Contrast-enhanced ultrasound Carotid atherosclerotic plaques Ischemic stroke

Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis

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World Journal of Gastroenterology 2015年第35期21卷 10104-10112页

作者： ying-chun wang Wei-Zong Kong Qing-Mei Jin Juan Chen Lei Dong Department of Gastroenterology the Second Affiliated HospitalXi’an Jiaotong University Department of Gastroenterology Affiliated Zhongshan Hospital of Dalian University

AIM: To investigate the effects of salvianolic acid B(Sal B) on the morphological characteristics and functions of liver mitochondria of rats with nonalcoholic steatohepatitis(NASH).METHODS: A total of 60 male Sprague-Dawley rats were randomly divided into three groups:(1) a normal group fed a normal diet;(2) an NASH model group; and(3) a Sal B-treated group fed a high-fat diet. Two rats from each group were executed at the end of the 12 th week to detect pathological changes. The rats in the Sal B-treated group were gavaged with 20 m L/kg Sal B(1 mg/m L) daily. The model group received an equal volume of distilled water as a control. At the end of the 24 th weekend, the remaining rats were executed. Serum biochemical parameters and liver histological characteristics were observed. Malondialdehyde(MDA) and superoxide dismutase(SOD) in the liver were determined. Protein expression of Cyt C and caspase-3 was determined by immunohistochemistry. The m RNA transcripts of mitofusin-2(Mfn2) and NF-κB in the liver tissue were detected by real-time PCR. Mitochondrial membrane potential was detected using a fluorescence spectrophotometer. Mitochondrial respiratory function was detected using a Clark oxygen ***: The model group showed significantly higher ALT, AST, TG, TC and MDA but significantly lower SOD than the normal group. In the model group,the histological characteristics of inflammation and steatosis were also evident; mitochondrial swelling and crest were shortened or even disappeared. Cyt C(18.46 ± 1.21 vs 60.01 ± 3.43, P < 0.01) and caspase-3 protein expression(30.26 ± 2.56 vs 83.31 ± 5.12, P < 0.01) increased significantly. The m RNA expression of NF-κB increased(0.81 ± 0.02 vs 0.91 ± 0.03, P < 0.05), whereas the m RNA expression of Mfn2 decreased(1.65 ± 0.31 vs 0.83 ± 0.16, P < 0.05). Mitochondrial membrane potential also decreased and breathing of rats was weakened. Steatosis and inflammation degrees in the treatment group were significantly allev

关键词： Nonalcoholic steatohepatitis Salvianolic acid B Ap