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Design strategies for rechargeable aqueous metal-ion batteries

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Science China Chemistry 2024年第1期67卷 165-190页

作者： Yang Li Xin Zhao Yifu Gao yichen ding Zhichun Si Liubing Dong Dong Zhou Feiyu Kang Tsinghua Shenzhen International Graduate School Tsinghua UniversityShenzhen 518055China College of Chemistry and Materials Science Jinan UniversityGuangzhou 511443China

Rechargeable aqueous metal-ion batteries(AMBs)have attracted extensive scientific and commercial interest due to their potential for cost-effective,highly safe,and scalable stationary energy ***,their limited output voltage,inadequate energy density,and poor reversibility of ambiguous electrode reactions in aqueous electrolytes strongly limit their practical *** review aims to elucidate the challenges of existing AMBs from the material design to whole device *** summarize the emerging electrochemistry,fundamental properties,and key issues in interfacial behaviors of various classes of prevailing AMBs,including aqueous alkali metal-ion batteries and multivalent-ion batteries,and present an appraisal of recent advances for addressing the performance ***,the progress of zinc-ion batteries is highlighted to provide a ubiquitous guideline for their commercialization in the grid-scale energy ***,we figure out the dominating general challenges for achieving high-performance AMBs,laying out a perspective for future breakthroughs.

关键词： aqueous metal-ion batteries aqueous alkali metal-ion batteries zinc-ion batteries interfacial behavior stationary energy storage

Effect of heat-moisture treatment to raw paddy rice(Oryza sativa L.)On cooked rice properties

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Journal of Future Foods 2021年第2期1卷 179-186页

作者： Sukanya Thuengtung Sunantha Ketnawa yichen ding Yukiharu Ogawa Gratuate School of Horticulture Chiba UniversityMatsudo 271-8501Japan Faculty of Medicine Chiang Mai UniversityChiang Mai 50200Thailand

Heat moisture treatment is safe and non-chemical use method for modifying physicochemical properties and digestibility of *** starch digestion in rice product would provide numerous health benefi ts for the *** study investigated the heat-moisture treatment to the raw paddy rice at 60 and 80ºC for 4 and 24 h,and their effects on the attributes of cooked *** fi rmness,adhesiveness,starch hydrolysis and morphological changes during in vitro digestion were *** showed that heat-moisture treatment to raw paddy rice for 24 h signifi cantly reduced the moisture content and could increase the total starch content of the rice *** apparent amylose content ranged from 23.83%to 25.65%at the variation in the values between treated and untreated *** in the firmness and reduction in the starch hydrolysis was found in rice treated by longer heating time of 24 ***,the adhesiveness of cooked rice was decreased when increasing the heating *** morphological observation showed that the treated rice exhibited a honey-comb-like structure during simulated gastric digestion,while the untreated rice displayed a non-uniform ***,the porous structure observed in all digested rice grains during simulated small intestinal digestion could favor the starch *** study showed that the heat-moisture treatment to the raw paddy rice at certain conditions obviously influenced the attributes of cooked rice,especially on the starch hydrolysis,which would provide a fundamental knowledge to enable development and improvement of slow digestion rice products.

关键词： Heat-moisture treatment Paddy rice Simulated in vitro digestion Physicochemical property Starch hydrolysis

TNFR2 is a potent prognostic biomarker for post-transplant lung metastasis in patients with hepatocellular carcinoma

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Chinese Journal of Cancer Research 2023年第1期35卷 66-80页

作者： Huigang Li Zuyuan Lin Jianyong Zhuo Modan Yang Wei Shen Zhihang Hu yichen ding Hao Chen Chiyu He Xinyu Yang Siyi Dong Xuyong Wei Beicheng Sun Shusen Zheng Ren Lang Di Lu Xiao Xu Zhejiang University School of Medicine Hangzhou 310058China Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryAffiliated Hangzhou First People's HospitalZhejiang University School of MedicineHangzhou 310006China The Institute for Organ Repair and Regenerative Medicine of Hangzhou Hangzhou 310006China Institute of Organ Transplantation Zhejiang UniversityHangzhou 310003China National Center for Healthcare Quality Management in Liver Transplant Hangzhou 310003China Department of Hepatobiliary Surgery the Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Department of Hepatobiliary and Pancreatic Surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalHangzhou 311112China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 31003China Department of Hepatobiliary Surgery Beijing Chaoyang Hospital Affiliated to Capital Medical UniversityBeijing 100020China

Objective:Lung metastasis is a common and fatal complication of liver transplantation for hepatocellular carcinoma(HCC).The precise prediction of post-transplant lung metastasis in the early phase is of great ***:The mRNA profiles of primary and paired lung metastatic lesions were analyzed to determine key signaling *** enrolled 241 HCC patients who underwent liver transplantation from three *** microarrays were used to evaluate the prognostic capacity of tumor necrosis factor(TNF),tumor necrosis factor receptor 1(TNFR1),and TNFR2,particularly for post-transplant lung ***:Comparison of primary and lung metastatic lesions revealed that the TNF-dependent signaling pathway was related to lung metastasis of *** expression of TNF was degraded in comparison to that in para-tumor tissues(P<0.001).The expression of key receptors in the TNF-dependent signaling pathway,TNFR1 and TNFR2,was higher in HCC tissues than in para-tumor tissues(P<0.001).TNF and TNFR1 showed no relationship with patients’outcomes,whereas elevated TNFR2 in tumor tissue was significantly associated with worse overall survival(OS)and increased recurrence risk(5-year OS rate:31.9%vs.62.5%,P<0.001).Notably,elevated TNFR2 levels were also associated with an increased risk of post-transplant lung metastasis(hazard ratio:1.146;P<0.001).Cox regression analysis revealed that TNFR2,Hangzhou criteria,age,and hepatitis B surface antigen were independent risk factors for post-transplant lung metastasis,and a novel nomogram was established *** nomogram achieved excellent prognostic efficiency(area under time-dependent receiver operating characteristic=0.755,concordance-index=0.779)and was superior to conventional models,such as the Milan ***:TNFR2 is a potent prognostic biomarker for predicting post-transplant lung metastasis in patients with HCC.A nomogram incorporating TNFR2 deserves to be a helpful prognostic tool in liver transplantatio

关键词： Lung metastasis hepatocellular carcinoma liver transplantation nomogram

Subvoxel light-sheet microscopy for high-resolution high-throughput volumetric imaging of large biomedical specimens

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Advanced Photonics 2019年第1期1卷 45-57页

作者： Peng Fei Jun Nie Juhyun Lee yichen ding Shuoran Li Hao Zhang Masaya Hagiwara Tingting Yu Tatiana Segura Chih-Ming Ho Dan Zhu Tzung KHsiaic Huazhong University of Science and Technology School of Optical and Electronic InformationWuhanChina Huazhong University of Science and Technology Britton Chance Center for Biomedical PhotonicsWuhan National Laboratory for OptoelectronicsWuhanChina University of California Los AngelesDepartment of BioengineeringLos AngelesCaliforniaUnited States University of Texas at Arlington Joint Department of Bioengineering of UT Arlington/UT SouthwesternArlingtonTexasUnited States University of California Los AngelesSchool of MedicineLos AngelesCaliforniaUnited States University of California Los AngelesChemical and Biomolecular Engineering DepartmentLos AngelesCaliforniaUnited States Osaka Prefecture University Nanoscience and Nanotechnology Research CenterResearch Organization for the 21st CenturyOsakaJapan University of California Los AngelesMechanical and Aerospace Engineering DepartmentLos AngelesCaliforniaUnited States

A key challenge when imaging whole biomedical specimens is how to quickly obtain massive cellular information over a large field of view(FOV).We report a subvoxel light-sheet microscopy(SLSM)method enabling high-throughput volumetric imaging of mesoscale specimens at cellular resolution.A nonaxial,continuous scanning strategy is developed to rapidly acquire a stack of large-FOV images with three-dimensional(3-D)nanoscale shifts ***,by adopting a subvoxel-resolving procedure,the SLSM method models these low-resolution,cross-correlated images in the spatial domain and can iteratively recover a 3-D image with improved resolution throughout the *** technique can surpass the optical limit of a conventional light-sheet microscope by more than three times,with high acquisition speeds of gigavoxels per *** fast reconstruction of 3-D cultured cells,intact organs,and live embryos,SLSM method presents a convenient way to circumvent the trade-off between mapping large-scale tissue(>100 mm3)and observing single cell(∼1-μm resolution).It also eliminates the need of complicated mechanical stitching or modulated illumination,using a simple light-sheet setup and fast graphics processing unit-based computation to achieve high-throughput,high-resolution 3-D microscopy,which could be tailored for a wide range of biomedical applications in pathology,histology,neuroscience,etc.

关键词： light-sheet microscopy subvoxel-resolving reconstruction large tissue imaging high-throughput volumetric imaging

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浅谈山区铁路站场设计——以瑞梅铁路为例

铁道勘测与设计 2023年第3期 28-30,44页

作者：丁祎晨中铁第四勘察设计院集团有限公司线站院武汉430063

山区铁路是我国铁路网的重要组成部分,发挥着拉动地方经济、保障区域交通的重要作用。山区铁路受自然条件限制,其站场设计需结合地形地质特征、线位及桥隧方案等内容进行特殊设计。通过对山区铁路特点的分析,结合瑞梅铁路站场设计实例,... 详细信息

山区铁路是我国铁路网的重要组成部分,发挥着拉动地方经济、保障区域交通的重要作用。山区铁路受自然条件限制,其站场设计需结合地形地质特征、线位及桥隧方案等内容进行特殊设计。通过对山区铁路特点的分析,结合瑞梅铁路站场设计实例,归纳总结山区铁路站场设计的部分要点。

关键词：山区铁路站场设计瑞梅铁路

基于手机定位数据的西宁市老年人公园绿地可达性预测

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干旱区地理 2023年第10期46卷 1744-1756页

作者：赵志远丁逸尘杨喜平吴升福州大学数字中国研究院(福建) 福建福州350003 空间数据挖掘与信息共享教育部重点实验室福建福州350003 海西政务大数据应用协同创新中心福建福州350002 自然资源部城市国土资源监测与仿真重点实验室广东深圳518000 陕西师范大学地理科学与旅游学院陕西西安710119

预测并分析老年人公园绿地资源可获取性对提高老年人生活品质、有效应对我国老龄化社会带来的有关挑战具有重要意义。为使城市公园绿地的分布更具“适老性”,基于西宁市带有年龄标识信息的手机位置数据,识别并预测老年人口的空间分布,... 详细信息

预测并分析老年人公园绿地资源可获取性对提高老年人生活品质、有效应对我国老龄化社会带来的有关挑战具有重要意义。为使城市公园绿地的分布更具“适老性”,基于西宁市带有年龄标识信息的手机位置数据,识别并预测老年人口的空间分布,运用高斯两步移动搜索法对老年人公园绿地可达性进行研究及预测。结果表明:(1)2018—2028年老年人数显著增加,且老年人数变化量呈现中心城区及远郊区较低、近郊区高的环状分布特征。(2)10 a间,老年人公园绿地可达性的空间分布总体格局未发生显著变化,但可达性水平总体下降。(3)2018—2028年老年人公园绿地可达性相对变化量较大,步行和公交30 min条件下,约87%的空间单元的公园绿地可达性降低超过70%。研究结果补充了高空间精度下城市老年人公园绿地可达性研究的不足,提供了面向老龄化发展需求的城市未来公园绿地规划建议。

关键词：老年人公园绿地手机数据可达性高斯两步移动搜索法西宁市

长三角汽车制造产业链投资网络空间特征及影响因素

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地理研究 2024年第7期43卷 1715-1734页

作者：丁乙宸黄亚平鲁仕维谢来荣张梦洁华中科技大学建筑与城市规划学院武汉430074 湖北省城镇化工程技术研究中心武汉430074 自然资源部城市仿真重点实验室武汉430074 武汉华中科大建筑规划设计研究院有限公司武汉430074

以城市群、都市圈为主的城市区域已经成为代表我国参与全球竞争及合作的主要载体,并且其内部的产业链功能组织状况对城市区域的一体化水平起到至关重要的影响,而长三角作为全国对外开放程度最高、经济发展最具活力的城市区域之一,对其... 详细信息

以城市群、都市圈为主的城市区域已经成为代表我国参与全球竞争及合作的主要载体,并且其内部的产业链功能组织状况对城市区域的一体化水平起到至关重要的影响,而长三角作为全国对外开放程度最高、经济发展最具活力的城市区域之一,对其汽车制造产业链投资网络开展研究可以为其他城市群提供一定的参考及示范作用。本文基于长三角的工商企业注册数据库,借助社会网络分析、社区发现等方法,从汽车制造产业链整体、上游和中游环节入手来分析其投资网络的多尺度空间特征,并运用地理探测器来探析各环节投资网络的影响因素。结果显示:(1)长三角汽车制造产业链整体、上游、中游投资网络分别呈“双强核多中心辐射状”“单强核多中心放射状”“单弱核多中心辐射状”的空间结构。(2)长三角汽车制造产业链整体、上游、中游投资网络可分别划分为4、4、6个社区,并且中游的模块化水平较好。(3)整体和上游投资网络的城市节点中心度高值区主要沿沪宁合杭甬发展带、南部沿海发展带分布。(4)政策支持水平、经济产业水平、对外经济水平、人力资源水平是影响汽车制造产业链各环节投资网络空间格局的主要因素,但同一因子对不同环节的影响强度有所差异。(5)交互探测结果显示,各环节投资网络的不同影响因子交互后表现为双因子增强和非线性增强2种,其中双因子增强效应占主导。相关研究结果对于提升长三角内部的城市间产业分工协作,促进区域一体化发展具有重要意义。

关键词：产业链投资网络空间特征影响因素长三角

县级国土空间规划中“三区三线”划定研究——以延川县为例

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城市发展研究 2020年第5期27卷 1-9页

作者：丁乙宸刘科伟程永辉冯锐西北大学城市与环境学院

在县域层面开展"双评价"、科学划定"三区三线"是县级国土空间总体规划的关键内容之一,也是实现全域、全要素空间管制的重要手段。首先结合县级层面空间规划的编制现实与相关研究,对当前"三区三线"划定在如何对待既有法定规划成果、如何... 详细信息

在县域层面开展"双评价"、科学划定"三区三线"是县级国土空间总体规划的关键内容之一,也是实现全域、全要素空间管制的重要手段。首先结合县级层面空间规划的编制现实与相关研究,对当前"三区三线"划定在如何对待既有法定规划成果、如何看待划定的先后次序、如何实施评价的技术方法三个方面的问题进行了深入思考。在此基础上,提出了县级国土空间规划中"三区三线"划定的基本思路,即:应在充分尊重既有法定规划成果的基础上,因地制宜地构建国土空间开发适宜性评价指标体系,先结合生态保护重要性评价划定生态空间,再结合城镇建设适宜性评价与城镇建设承载能力评价、农业生产适宜性评价与农业生产承载能力评价协调划定城镇空间与农业空间,最后对上述划定的各类空间管制分区、既有法定控制线进行协调,从而形成县级国土空间规划中的"三区三线"。并以延川县为例开展实证研究,以期为县级国土空间规划中"三区三线"的划定提供参考。

关键词： “三区三线” 国土空间开发适宜性资源环境承载能力县级国土空间总体规划

基于宏基因组测序的星级酒店集中空调系统微生物污染特征

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环境与职业医学 2022年第11期39卷 1284-1290页

作者：刘永萍丁一辰王凯张莉君苏瑾复旦大学公共卫生学院上海200032 上海市疾病预防控制中心公共服务与健康安全评价所上海200336 上海市疾病预防控制中心健康危害因素监测与控制所上海200336

[背景]公共场所集中空调通风系统(集通系统)的使用有利于改善室内空气质量,增加人群体感舒适度。但是,集通系统也可能成为室内空气致病微生物污染的潜在载体。[目的]了解星级酒店集通系统微生物污染特征及病原微生物分布特点,为有效控... 详细信息

[背景]公共场所集中空调通风系统(集通系统)的使用有利于改善室内空气质量,增加人群体感舒适度。但是,集通系统也可能成为室内空气致病微生物污染的潜在载体。[目的]了解星级酒店集通系统微生物污染特征及病原微生物分布特点,为有效控制其污染提供依据。[方法]按照WS 394—2012《公共场所集中空调通风系统卫生规范》要求,在2020年9月9日随机选取上海市中心城区2家星级酒店(A和B)的2套集通系统(启用年代分别为2002年、1998年)进行送风中微生物和送风中可吸入颗粒物(PM10)、风管内表面积尘量和微生物、冷却水和冷凝水中嗜肺军团菌等卫生学评价。同时在每套集通系统采集风管内表面样品3件,滤网表面、冷凝水、冷却水样品各1件,2套集通系统共采集12件样品进行Illumina HiSeq宏基因组测序,依据样品类型将其分为3组:风管组、滤网组、水样组。计算α多样性指数(包括Shannon指数、Simpson指数、Chao1指数、ACE指数、良好覆盖指数),反映微生物群落组成特征;通过主成分分析研究3组的β多样性,确定各组样品微生物群落相似程度。[结果]酒店A集通系统送风中细菌总数、真菌总数最大值分别为1158、344 CFU·m^(-3),酒店B分别为2000、532 CFU·m^(-3)。两酒店β-溶血性链球菌均未检出,送风中可吸入颗粒物、风管内表面微生物及积尘量、冷却水和冷凝水样品中嗜肺军团菌指标均符合卫生标准要求。Illumina HiSeq宏基因组测序结果表明,12个样本中共测得17322种微生物,其中细菌微生物群占已分类基因的97.31%,其余2.69%来自真菌、病毒和寄生虫。在种水平上,表皮葡萄球菌、假单胞菌、链格孢菌、马拉色菌等为本次调查测得的优势微生物类群。α多样性分析结果表明3组样品的Shannon、Simpson、Chao1、ACE指数值均为风管>滤网>水样。各组样品良好覆盖指数均接近于1。主成分分析表明,两个主成分贡献率分别为19.27%、14.25%,其中,滤网及风管组样品较好地聚为一类。[结论]2家星级酒店除集通系统送风中微生物污染较严重外,总体卫生状况良好。宏基因组测序发现集通系统微生物类群结构复杂,物种组成包括细菌、真菌、病毒和寄生虫等;不同类型样品物种组成有差别,滤网和风管的样品物种组成接近且以人源性病原微生物为主,提示集通系统潜在的生物安全隐患不容忽视。

关键词：宏基因组学集中空调系统微生物污染酒店