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Numerical investigation on thermomechanical behavior of alumina–calcium hexaluminate refractories for purging plug

Journal of Iron and Steel Research(International) 2024年第2期31卷 389-400页

作者： Li-ping Pan Ya-wei Li Fang-guan Tan yi-chen chen yang-fan Xu Zhu He Bao-kuan Li The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan430081HubeiChina National-Provincial Joint Engineering Research Center of High Temperature Materials and Lining Technology Wuhan University of Science and TechnologyWuhan430081HubeiChina

Alumina–spinel refractories used in slit-type purging plugs are susceptible to cross-sectional damage,resulting in a serious mismatch between their service life and that of ***–calcium hexaluminate refractories have gradually become the new trend in purging plug materials with the development of refining *** thermomechanical damage of slit-type purging plugs with alumina–calcium hexaluminate refractory was investigated by the thermo-solid coupling *** with the polynomial fitting and design of experiments methods,the influence of thermophysical parameters on temperature and thermal stress of alumina–calcium hexaluminate refractories for purging plugs was systematically *** results show that the maximum thermal stress of the purging plugs appears during the stages of steel transporting and stirring,and the vulnerable parts are located above Y=0.323 *** thermal conductivity and the coefficient of thermal expansion of the material are the most sensitive parameters to the temperature and thermal stress inside the structure,*** addition of more calcium hexaluminate can relieve the stress concentration and large deformation around the ***,when the content of calcium hexaluminate is 47 wt.%and in the form of aggregate-binder,the temperature and thermal stress distribution inside the refractory are optimal,which can effectively improve the service life of the slit-type purging plug.

关键词： Purging plug Thermomechanical damage Refractory Design of experiments method Stress

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S-scheme heterojunction construction of Fe/BiOCl/BiVO_(4) for enhanced photocatalytic degradation of ciprofloxacin

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Progress in Natural Science:Materials International 2024年第2期34卷 290-303页

作者： Guanlong Yu Qifang Sun yi yang Si chen Yuannan Long yifu Li Shiyong Ge Dian Zheng School of Hydraulic and Environmental Engineering Changsha University of Science&TechnologyChangsha410114PR China School of Environmental Engineering Wuhan Textile UniversityWuhan430073PR China Key Laboratory of Dongting Lake Aquatic Eco-Environmental Control and Restoration of Hunan Province Changsha410114PR China

With the growing problem of water pollution caused by antibiotics,the development of photocatalysts with high photogenerated carrier separation efficiency is crucial.A high-efficiency microsphere Fe/BiOCl/BiVO_(4)with Sscheme heterojunction was synthesized by solvothermal method and its ciprofloxacin(CIP)degradation performance were investigated under visible ***,FT-IR,SEM,EDS,HRTEM and XPS results show that the photocatalytic have good crystallization,morphology and the formed a *** photocatalytic performance of Fe/BiOCl/BiVO_(4)for CIP was superior to pure BiOCl and BiVO_(4)due to the microsphere and formed heterostructure between BiOCl and BiVO_(4).The influencing factors of CIP degradation by Fe/BiOCl/BiVO_(4)were investigated,and the results showed that Fe/BiOCl/BiVO_(4)had high degradation efficiency not only at pH 5-9,but also in the presence of inorganic Cl^(-),NO_(3)^(-)and metal *** the optimal conditions,the degradation rate of CIP was up to 100%in 75 *** addition to CIP,the Fe/BiOCl/BiVO_(4)photocatalysts degraded other organic pollutants,such as tetracycline,oxytetracycline,chlortetracycline,ofloxacin,levofloxacin,and rhodamine B,by more than 92%.The main active species were photogenerated holes(h^(+))and superoxide radicals(·O_(2)^(-)).In addition,possible intermediates and toxicity of intermediates were analyzed and five potential pathways for CIP degradation were proposed.

关键词： BiOCl/BiVO_(4) Fe^(3+)doping Organic pollutant Photocatalysis S-scheme heterojunction

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Wave Attenuation and Turbulence Driven by Submerged Vegetation Under Current-Wave Flow

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China Ocean Engineering 2024年第4期38卷 602-611页

作者： HUANG Yu-ming Ding Lei WANG yi-fei chen Ben yang Xiao-yu DOU Xi-ping School of Water Resources and Hydropower Engineering Wuhan UniversityWuhan430072China Key Laboratory of Port Waterway and Sedimentation Engineering of MOTNanjing Hydraulic Research InstituteNanjing 210029China

A set of laboratory experiments are carried out to investigate the effect of following/opposing currents on wave *** vegetation canopies with aligned and staggered configurations were tested under the condition of various regular wave heights and current velocities,with the constant water depth being 0.60 m to create the desired submerged *** show that the vegetation-induced wave dissipation is enhanced with the increasing incident wave height.A larger velocity magnititude leads to a greater wave height attenuation for both following and opposing current ***,there is a strong positive linear correlation between the damping coefficientβand the relative wave height H_(0)/h,especially for pure wave *** the velocity profile,the distributions of U_(min)and U_(max)show different patterns under combined wave and *** time-averaged turbulent kinetic energy(TKE)vary little under pure wave and U_(c)=±0.05 m/s *** the increase of flow velocity amplitude,the time-averaged TKE shows a particularly pronounced increase trend at the top of the *** vegetation drag coefficients are obtained by a calibration *** empirical relations of drag coefficient with Reynolds and Keulegane-Carpenter numbers are proposed to further understand the wave-current-vegetation interaction mechanism.

关键词： wave attenuation rigid vegetation following and opposing currents turbulent kinetic energy

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Metabolic and proteostatic differences in quiescent and active neural stem cells

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Neural Regeneration Research 2024年第1期19卷 43-48页

作者： Jiacheng Yu Gang chen Hua Zhu yi Zhong Zhenxing yang Zhihong Jian Xiaoxing Xiong Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Adult neural stem cells are neurogenesis progenitor cells that play an important role in ***,neural regeneration may be a promising target for treatment of many neurological *** regenerative capacity of adult neural stem cells can be chara cterized by two states:quiescent and *** adult neural stem cells are more stable and guarantee the quantity and quality of the adult neural stem cell *** adult neural stem cells are chara cterized by rapid proliferation and differentiation into neurons which allow for integration into neural *** review focuses on diffe rences between quiescent and active adult neural stem cells in nutrition metabolism and protein ***,we discuss the physiological significance and underlying advantages of these diffe *** to the limited number of adult neural stem cells studies,we refe rred to studies of embryonic adult neural stem cells or non-mammalian adult neural stem cells to evaluate specific mechanisms.

关键词： adult neurogenesis cell metabolic pathway cellular proliferation neural stem cell niches neural stem cells neuronal differentiation nutrient sensing pathway proteostasis

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Prognostic value of time-varying dead space estimates in mechanically ventilated patients with acute respiratory distress syndrome

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Journal of Intensive Medicine 2024年第2期4卷 187-193页

作者： Lianlian Jiang Hui chen Jianfeng Xie Ling Liu yi yang Jiangsu Provincial Key Laboratory of Critical Care Medicine Department of Critical Care MedicineZhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsuChina Department of Critical Care Medicine The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhouJiangsuChina

Background The dead space fraction(VD/VT)has proven to be a powerful predictor of higher mortality in acute respiratory distress syndrome(ARDS).However,its measurement relies on expired carbon dioxide,limiting its widespread application in clinical *** estimates employing routine variables have been found to be reliable substitutes for direct measurement of VD/*** this study,we evaluated the prognostic value of these dead space estimates obtained in the first 7 days following the initiation of *** This retrospective observational study was conducted using data from the Chinese database in intensive care(CDIC).Eligible participants were adult ARDS patients receiving invasive mechanical ventilation while in the intensive care unit between 1st January 2014 and 31st March *** collected data during the first 7 days of ventilation to calculate various dead space estimates,including ventilatory ratio(VR),corrected minute ventilation(V_(Ecorr)),VD/VT(Harris–Benedict),VD/VT(Siddiki estimate),and VD/VT(Penn State estimate)longitudinally.A time-dependent Cox model was used to handle these time-varying *** A total of 392 patients(median age 66[interquartile range:55–77]years,median SOFA score 9[interquartile range:7–12])were finally included in our analysis,among whom 132(33.7%)patients died within 28 days of ***(hazard ratio[HR]=1.04 per 0.1 increase,95%confidence interval[CI]:1.01 to 1.06;P=0.013),V_(Ecorr)(HR=1.08 per 1 increase,95%CI:1.04 to 1.12;P1.3,V_(Ecorr)>7.53,a

关键词： Acute respiratory distress syndr ome Mechanical ventilation Dead space 28-day mortality

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Cutting performance of saw blades with microtextured rougher and finisher sawteeth

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Advances in Manufacturing 2024年第2期12卷 317-334页

作者： yang Lu Jian-Xin Deng Zhi-Hui Zhang Jia-Xing Wu Ran Wang yi-chen Bao Key Laboratory of High Efficiency and Clean Mechanical Manufacture of MOE School of Mechanical EngineeringShandong UniversityJinan250061People’s Republic of China

The problems of severe sawtooth wear,harsh sawing noise,and low surface quality during the processing of circular saw blades need to be *** improve the cutting performance of TiC-based cermet saw blades,microtextures parallel to the cutting edge were fabricated on rough and fine sawteeth by laser *** cutting tests were performed on a sawing platform under lubricated *** of the sawing arc length and working sawtooth cutting force variations were developed for sawing steel pipes,and the accuracy of the sawing force model was verified *** results indicate that the variations in the sawing force are proportional to the sawing arc *** circular saw blades with microtextures that did not penetrate the sawtooth rake face exhibited the lowest cutting force,sawing noise,and highest machined surface ***,the worn-out distance of the rougher and finisher sawteeth was reduced by approximately 7.4%and 44.1%,respectively,compared with conventional circular saw *** main failure modes of sawteeth were tip wear,rake face adhesion,and oxidative *** addition,the mechanism by which the textures improve the cutting and wear properties of TiC-based circular saw blades was *** study provided a significant concept for enhancing the cutting performance of circular saw blades and improving the machined surface quality.

关键词： Circular saw blades Micro textures Cutting performance Wear performance

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Spatiotemporal dynamics of the social structure of Indo-Pacific humpback dolphins(Sousa chinensis)in Xiamen waters from 2007 to 2019

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Zoological Research 2024年第2期45卷 439-450页

作者： yi Lu Xin-Rong Xu Bing-Yao chen Thomas A Jefferson Holly Fearnbach Guang yang Jiangsu Key Laboratory for Biodiversity and Biotechnology College of Life SciencesNanjing Normal UniversityNanjingJiangsu 210023China Clymene Enterprises LakesideCalifornia 92040USA Marine Mammal Research SR3SeaLife ResponseRehabilitation and ResearchWA 98275USA Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) No.1119Haibin RoadNansha DistrictGuangzhouGuangdong 511458China

As highly social animals,Indo-Pacific humpback dolphins(Sousa chinensis)exhibit community ***,our understanding of the external and internal factors influencing these dynamics,as well as their spatiotemporal variations,is still *** the present study,variations in the social structure of an endangered Indo-Pacific humpback dolphin population in Xiamen Bay,China,were monitored over two distinct periods(2007–2010 and 2017–2019)to analyze the effects of habitat utilization and the composition of individuals within the *** both periods,the population demonstrated a strikingly similar pattern of social differentiation,characterized by the division of individuals into two main clusters and one small ***,the two primary clusters occupied the eastern and western waters,respectively,although the core distribution area of the eastern cluster shifted further eastward between the two *** this distribution shift,the temporal stability of the social structure and inter-associations within the eastern cluster remained unaffected.A subset of 16individuals observed in both periods,comprising 51.6%and 43.2%of the population in each respective period,emerged as a foundational element of the social structure and may be responsible for sustaining social structure stability,especially during the 2007–2010 *** observations suggest that the composition of dominant individuals,an internal factor,had a more substantial influence on the formation of the social network than changes in habitat use,an external ***,the study proposes distinct conservation measures tailored to each of the two main clusters.

关键词： Social differentiation Social structure Sousa chinensis Dynamics Conservation

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Comprehensive insight into the occurrence characteristics,influencing factors and risk assessments of antibiotics in the Chaohu Basin

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Frontiers of Environmental Science & Engineering 2024年第5期18卷 57-71页

作者： Shuanggang Hu Hongzhi Zhang Yongjie yang Kangping Cui Junjie Ao Xuneng Tong Mengchen Shi yi Wang Xing chen chenxuan Li yihan chen School of Resources and Environmental Engineering Hefei University of TechnologyHefei230009China Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai200092China Department of Civil & Environmental Engineering National University of SingaporeSingapore117576Singapore College of Resources and Environment Anhui Agricultural UniversityHefei230036China

The pollution of antibiotics in aquatic environments has received extensive ***,research on antibiotic contamination in river-lake systems,a significant form of modern aquatic environments,still needs to be *** study focuses on the Chaohu Basin(China)investigating the occurrence characteristics,influencing factors,and risk assessments of antibiotics in the river-lake *** total antibiotic concentrations in the water phase and sediment phase were 3.14–1887.49 ng/L and 0.92–1553.75 ng/g,*** was the predominant antibiotic in the water phase,whereas tetracycline prevailed in the sediment *** differences in concentration and structural composition of antibiotics between the tributaries(river system)and Chaohu Lake were observed,indicating the involvement of various geochemical processes in the attenuation of antibiotics during transport to the receiving *** analysis suggested that the western river is the primary source of antibiotics in Chaohu *** nutrient influx in heavily polluted areas is crucial to addressing the escalating issue of antibiotic pollution in the river-lake *** widespread occurrence of clindamycin in the waters is likely due to wastewater treatment plant discharges,and high-intensity human activities continue to exacerbate antibiotic *** assessment indicated that sulfamethoxazole,tetracycline,lincomycin,and clindamycin ranked in the top four with the highest risks to the most sensitive aquatic ***,the antibiotics presented no risk to consumer *** study provides valuable insights for controlling antibiotic pollution in riverlake systems.

关键词： Antibiotics Occurrence characteristics Influencing factors Risk assessments River-lake system

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High patatin like phospholipase domain containing 8 expression as a biomarker for poor prognosis of colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 787-797页

作者： Peng-yang Zhou De-Xiang Zhu yi-Jiao chen Qing-yang Feng yi-Hao Mao Ao-Bo Zhuang Jian-Min Xu Department of General Surgery Zhongshan Hospital Fudan UniversityShanghai 200032China

BACKGROUND Patatin like phospholipase domain containing 8(PNPLA8)has been shown to play a significant role in various cancer *** studies have focused on its roles as an antioxidant and in lipid ***,the role of PNPLA8 in colorectal cancer(CRC)progression is *** To explore the prognostic effects of PNPLA8 expression in *** A retrospective cohort containing 751 consecutive CRC patients was ***8 expression in tumor samples was evaluated by immunohistochemistry staining and semi-quantitated with immunoreactive *** patients were divided into high and low PNPLA8 expression groups based on the cut-off va-lues,which were calculated by X-tile *** prognostic value of PNPLA8 was identified using univariate and multivariate Cox regression *** over-all survival(OS)rates of CRC patients in the study cohort were compared with Kaplan-Meier analysis and Log-rank *** PNPLA8 expression was significantly associated with distant metastases in our cohort(P=0.048).CRC patients with high PNPLA8 expression indicated poor OS(median OS=35.3,P=0.005).CRC patients with a higher PNPLA8 expression at either stage I and II or stage III and IV had statistically significant shorter *** patients with left-sided colon and rectal cancer,the survival curves of two PN-PLA8-expression groups showed statistically significant *** analysis also confirmed that high PNPLA8 expression was an independent prog-nostic factor for overall survival(hazard ratio HR=1.328,95%CI:1.016-1.734,P=0.038).

关键词： Biomarker Colorectal cancer Expression level Overall survival Patatin like phospholipase domain containing 8 Prognosis

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Morphological disruption and visual tuning alterations in the primary visual cortex in glaucoma(DBA/2J)mice

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Neural Regeneration Research 2024年第1期19卷 220-225页

作者： yin yang Zhaoxi yang Maoxia Lv Ang Jia Junjun Li Baitao Liao Jing’an chen Zhengzheng Wu yi Shi yang Xia Dezhong Yao Ke chen Department of Ophthalmology Sichuan Provincial People’s HospitalMedical SchoolUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina The Clinical Hospital of chengdu Brain Science Institute MOE Key Lab for NeuroInformationSchool of Life Science and TechnologyUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Research Unit of NeuroInformation Chinese Academy of Medical SciencesChengduSichuan ProvinceChina Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic Medicine Peking Union Medical CollegeBeijingChina Health Management Center Sichuan Provincial Key Laboratory for Human Disease Gene StudySichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences(2019RU026) Sichuan Academy of Medical SciencesChengduSichuan ProvinceChina School of Electrical Engineering Zhengzhou UniversityZhengzhouHenan ProvinceChina

Glaucoma is a leading cause of irreve rsible blindness wo rldwide,and previous studies have shown that,in addition to affecting the eyes,it also causes abnormalities in the ***,it is not yet clear how the primary visual cortex(V1)is altered in *** study used DBA/2J mice as a model for spontaneous secondary *** aim of the study was to compare the electrophysiological and histomorphological chara cteristics of neurons in the V1between 9-month-old DBA/2J mice and age-matched C57BL/6J *** conducted single-unit recordings in the V1 of light-anesthetized mice to measure the visually induced responses,including single-unit spiking and gamma band *** morphology of layerⅡ/Ⅲneurons was determined by neuronal nuclear antigen staining and Nissl staining of brain tissue ***-seven neurons from eight DBA/2J mice and eighty-one neurons from eight C57BL/6J mice were *** with the C57BL/6J group,V1 neurons in the DBA/2J group exhibited weaker visual tuning and impaired spatial *** r,fewer neuro ns were observed in the V1 of DBA/2J mice compared with C57BL/6J *** findings suggest that DBA/2J mice have fewer neurons in the VI compared with C57BL/6J mice,and that these neurons have impaired visual *** findings provide a better understanding of the pathological changes that occur in V1 neuron function and morphology in the DBA/2J mouse *** study might offer some innovative perspectives regarding the treatment of glaucoma.

关键词： DBA/2J degeneration gamma band oscillations glaucoma primary visual cortex(V1) retina single-unit recording tuning curve

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