Metabolic and proteostatic differences in quiescent and active neural stem cells

作     者：Jiacheng Yu Gang Chen Hua Zhu Yi Zhong Zhenxing Yang Zhihong Jian Xiaoxing Xiong Jiacheng Yu;Gang Chen;Hua Zhu;Yi Zhong;Zhenxing Yang;Zhihong Jian;Xiaoxing Xiong

作者机构：Department of NeurosurgeryRenmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2024年第19卷第1期

页      面：43-48页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学] 

基　　金：supported by the National Natural Science Foundation of China No.82171336(to XX) 

主　　题：adult neurogenesis cell metabolic pathway cellular proliferation neural stem cell niches neural stem cells neuronal differentiation nutrient sensing pathway proteostasis 

摘      要：Adult neural stem cells are neurogenesis progenitor cells that play an important role in ***,neural regeneration may be a promising target for treatment of many neurological *** regenerative capacity of adult neural stem cells can be chara cterized by two states:quiescent and *** adult neural stem cells are more stable and guarantee the quantity and quality of the adult neural stem cell *** adult neural stem cells are chara cterized by rapid proliferation and differentiation into neurons which allow for integration into neural *** review focuses on diffe rences between quiescent and active adult neural stem cells in nutrition metabolism and protein ***,we discuss the physiological significance and underlying advantages of these diffe *** to the limited number of adult neural stem cells studies,we refe rred to studies of embryonic adult neural stem cells or non-mammalian adult neural stem cells to evaluate specific mechanisms.