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Influence of gallic acid on porcine neutrophils phosphodiesterase 4,IL-6,TNF-α and rat arthritis model

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Journal of Integrative Agriculture 2015年第4期14卷 758-764页

作者： JIANG Dai-xun ZHANG Mei-hua ZHANG Qian CHEN yi-shan MA Wen-jing WU Wei-peng MU Xiang CHEN Wu Beijing Key Laboratory of Traditional Chinese Veterinary Medicine Beijing University of Agriculture

Our previous studies showed that the anti-inflammatory effects of Paeonia lactiflora roots extract may be mediated, at least in part, through its gallic acid content, and this effect may be regulated in part by an inhibition on c AMP-phosphodiesterase（PDE）. To explore the anti-inflammatory effect and mechanism, the influence of gallic acid on neutrophils PDE4 activity and expression, TNF-α and IL-6 content and rat arthritis model were further studied. PDE4 activity and gene express were calculated respectively by substrate c AMP change examined with HPLC and real-time RT-PCR. The concentration of IL-6 and TNF-α in supernatant were assayed by ELISA method. Model of rat arthritis was caused by complete Freund＇s adjuvant. Results showed that gallic acid had a dose-dependent restraint on PDE4 activity of neutrophils in vitro, promoted significantly PDE4 A expression（P〈0.01）, and had no influence on the expressions of PDE4 B and 4D. However, PDE4 C expression was not detected. Gallic acid could promote IL-6 release（P〈0.05）, and inhibit TNF-α release of neutrophils（P〈0.05）. The experiment in vivo showed that gallic acid had obvious restraint on local inflammation of animal model（P〈0.05）. Therefore, the anti-inflammatory effect of gallic acid may be mediated in part through an inhibition on PDE4 activity and further an increase of IL-6 and a decrease of TNF-α of neutrophils, and this effect seemed to have no relationship with PDE4 expression.

关键词： gallic acid phosphodiesterase 4 inflammation IL-6 TNF-α neutrophils

Acidity-Driven Bidirectional Room-Temperature Spin-State Switch and Fluorescence Modulation of a Mononuclear Fe(II) Complex

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CCS Chemistry 2021年第8期3卷 2350-2358页

作者： yi-shan Ye Xiu-Qin Chen Kai-Yan Shen Ming-Liang Tong Xin Bao School of Chemical Engineering Nanjing University of Science and TechnologyNanjing 210094 School of Chemistry Sun Yat-Sen UniversityGuangzhou 510275

Room-temperature switchable materials showing multiple responses toward external stimuli are highly ***,we report bidirectional spin-state switch and fluorescence modulation of an Fe(II)complex(1)based on a rhodamine B 2-pyridinecarbaldehyde hydrazone ligand in both the solid state and *** complex is predominantly stabilized in the low-spin(LS)state at room temperature due to the strong ligand-field strength imposed by acylhydrazone pyridine.

关键词： room-temperature switch spin-state change fluorescence modulation Fe(II)complex labile coordination sphere

A Cluster-Based Random Key Revocation Protocol for Wireless Sensor Networks

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Journal of Electronic Science and Technology of China 2008年第1期6卷 10-15页

作者： yi Jiang Hao-shan Shi School of Electronics and Information Northwestern Polytechnical University Xi＇an 710072

In recent years,several random key pre-distribution schemes have been proposed to bootstrap keys for encryption,but the problem of key and node revocation has received relatively little *** this paper,based on a random key pre-distribution scheme using clustering,we present a novel random key revoca-tion protocol,which is suitable for large scale networks greatly and removes compromised information *** revocation protocol can guarantee network security by using less memory consumption and communication load,and combined by centralized and distributed revoca-tion,having virtues of timeliness and veracity for revoca-tion at the same time.

关键词： Cluster-based key pre-distribution,revocation wireless sensor networks.

Ytterbium-doped fiber ring laser in multi-pulse operation

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Optoelectronics Letters 2007年第6期3卷 401-403页

作者： YANG Ling-zhen WANG Yun-cai CHEN Guo-fu WANG yi-shan ZHAO Wei Physics Department Taiyuan University of Technology Taiyuan 030024 China State Key Laboratory of Transient Optics Technology Xi＇an Institute of Optics and Precision Mechanics ChineseAcademy of Sciences Xi＇an 710068 China

An Ytterbium-doped mode-locked fiber laser using the polarization sensitive isolator and polarization controllers (PC) is reported. In the normal dispersion, the fiber laser can oscillate at the multi-pulse states by adjusting the position of the PC. On the condition that the polarization state isn’t changed, the outputs of Ytterbium-doped mode-locked fiber laser change from single pulse to multi-pulse by increasing the pump power. The fiber laser can achieve different multi-pulse output by adjusting the PC1 and PC2 carefully.

关键词：镱元素纤维环激光多脉冲操作光纤元件

Catalytic protection of stannous ion by ascorbic acid in diphosphonic acids solutions

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Nuclear Science and Techniques 1998年第2期9卷 121-123页

作者： Liu Guo-Zheng Liu Fei Miao Zeng-Xing Wang yi-shan and Fang Ji-Dong (Isotope Department, China Institute of Atomic Energy, Beijing 102413) Isotope Department China Institute of Atomic Energy Beijing 102413 China

The protective ability of ascorbic acid(Vc) on stannous ion and the influence of light irradiation on the stability of stannous ion in diphosphonate medium at pH=5 have been examined in order to attain minimal loss of stannous ion during the production of lyophilized radiopharmaceutical *** sum of stanous ion and Vc was determined with iodometric *** was shown that the protective ability of Vc was still strong at Vc concentration much lower than that of stannous ion and the illumination by fluorescent lamp was unfavorable to the stability of stannous *** change of pH in the range 3-9 did not affect the action of Vc significantly.

关键词：锡离子稳定性骨造影工具

A CT Image Segmentation Algorithm Based on Level Set Method

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Chinese Journal of Biomedical Engineering(English Edition) 2006年第2期15卷 47-52页

作者： QU Jing-yi SHI Hao-shan School of Electronic and Information Northwestern Polytechnical UniversityXi''an710072China School of Electronic and InformationNorthwestern Polytechnical UniversityXi''an710072China

Level Set methods are robust and efficient numerical tools for resolving curve evolution in image segmentation. This paper proposes a new image segmentation algorithm based on Mumford-Shah module. The method is used t... 详细信息

关键词： Medical image segmentation,Level set,Mumford-Shah model,Curve evolution

Building a Community for the Senior Citizens Using the Idea of Vertical Farms

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Journal of Civil Engineering and Architecture 2015年第6期9卷 727-733页

作者： Shu-ying Tsai yi-shan Tsai Department of Architecture National Taipei University of Technology Taipei 10670 Republic of China

Global population growth and urbanization have posed increasing threats to the ecological environment. In an aging society, high-density living spaces have resulted in intensifying housing concerns for urban senior citizens. Among the rapid urban development, addressing the demands of senior citizens for suitable living environments and enabling senior city dwellers to engage in diversified social interactions are concerns that necessitate public attention. This study introduced the idea of the “vertical farm” to the living environments of senior citizens. By integrating vegetation appreciation and physical labor, vertical farming allows senior citizens to experience joy and a sense of accomplishment. In addition, these farms can change the monotonous and gloomy exteriors of concrete buildings. By conducting in-depth interviews with 12 senior citizens residing in the Happiness Community in Taipei City, by building vertical farms, senior citizens can experience joy and a sense of achievement at the psychological level and communicate with families, friends and neighbors in the community at a social level. At the environmental level, comprehensive ecological communities can be achieved. We explored how promoting vertical farms in a living environment can affect senior citizens at the psychological, social and environmental levels. The results can be used to build vertical farms that accommodate the needs of senior citizen living environments.

关键词： Vertical farm senior citizens urbanization

Personal knowledge on novel coronavirus pneumonia

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Chinese Medical Journal 2020年第9期133卷 1121-1122页

作者： Han-Yu-Jie Kang yi-shan Wang Zhao-Hui Tong Department of Respiratory and Critical Care Medicine Beijing Institute of Respiratory MedicineBeijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China

The epidemiological history of some patients infected with novel coronavirus(2019-nCoV)is unclear,and the incubation period of the virus can last for 2 weeks,even *** the period of latent infection or the period of incubation following infection,the disease may be *** in cases of influenza,some patients develop only upper respiratory tract infection,whereas others with a severe form of the disease develop *** may not have fever,mild cough,or apparent respiratory symptoms,and headache or gastrointestinal symptoms may be *** patients show insidious onset and slow progression,and do not appear to be ***,they may not receive attention or be *** patients with severe disease or critical illness may present with moderate-to-low-grade fever,but apparent fever may also be absent.

关键词： pneumonia respiratory infection

CORROSION INHIBITION OF STEARIC ACID LANGMUIR-BLODGETT MONOLAYERS ON IRON

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Chinese Chemical Letters 1993年第1期4卷 87-88页

作者： Wei XING yi Bin shan Du GUO Tian Hong LU Shi Ouan XI Laboratory of Electroanaiytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022

The Langmuir-Blodgett (LB) technique was used for the first time to study inhibition mechanism. Stearic acid Langmuir-Blodgett (SALB) monolayers showed a good inhibition effect on iron corrosion in neutral environment... 详细信息

关键词： Ho CORROSION INHIBITION OF STEARIC ACID LANGMUIR-BLODGETT MONOLAYERS ON IRON ACID