Catalytic protection of stannous ion by ascorbic acid in diphosphonic acids solutions

作     者：Liu Guo-Zheng Liu Fei Miao Zeng-Xing Wang Yi-Shan and Fang Ji-Dong (Isotope Department, China Institute of Atomic Energy, Beijing 102413) 

作者机构：Isotope Department China Institute of Atomic Energy Beijing 102413 China 

出 版 物：《Nuclear Science and Techniques》 (核技术（英文）)

年 卷 期：1998年第9卷第2期

页      面：121-123页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 070301[理学-无机化学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1006[医学-中西医结合] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 0817[工学-化学工程与技术] 0703[理学-化学] 100106[医学-放射医学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：锡离子 稳定性 骨造影工具 

摘      要：The protective ability of ascorbic acid(Vc) on stannous ion and the influence of light irradiation on the stability of stannous ion in diphosphonate medium at pH=5 have been examined in order to attain minimal loss of stannous ion during the production of lyophilized radiopharmaceutical *** sum of stanous ion and Vc was determined with iodometric *** was shown that the protective ability of Vc was still strong at Vc concentration much lower than that of stannous ion and the illumination by fluorescent lamp was unfavorable to the stability of stannous *** change of pH in the range 3-9 did not affect the action of Vc significantly.