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Intravitreal conbercept injection with panretinal photocoagulation for high-risk proliferative diabetic retinopathy with vitreous hemorrhage

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1066-1072页

作者： Yao Xu qing ye Wei Shen Department of Ophthalmology the Fourth Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina Department of Ophthalmology Suzhou Kowloon HospitalShanghai Jiao Tong University School of MedcineSuzhou 215000Jiangsu ProvinceChina Department of Ophthalmology the First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

AIM:To assess the clinical efficacy and safety of combining panretinal photocoagulation(PRP)with intravitreal conbercept(IVC)injections for patients with high-risk proliferative diabetic retinopathy(HR-PDR)complicated by mild or moderate vitreous hemorrhage(VH),with or without diabetic macular edema(DME).METHODS:Patients diagnosed with VH with/without DME secondary to HR-PDR and received PRP combined with IVC injections were recruited in this retrospective *** establishing the patient’s diagnosis,an initial IVC was performed,followed by prompt administration of *** cases who significant bleeding persisted and impeded the laser operation,IVC was sustained before supplementing with *** the completion of PRP,patients were meticulously monitored for a minimum of six *** therapy and IVC injections were judiciously adjusted based on fundus fluorescein angiography(FFA)*** effect and the incidence of adverse events were ***:Out of 42 patients(74 eyes),29 were male and 13 were female,with a mean age of 59.17±12.74y(33-84y).The diabetic history was between 1wk and 26y,and the interval between the onset of visual symptoms and diagnosis of HR-PDR was *** affected eye received 2.59±1.87(1-10)IVC injections and underwent 5.5±1.02(4-8)sessions of *** these,68 eyes received PRP following 1 IVC injection,5 eyes after 2 IVC injections,and 1 eye after 3 IVC *** absorption of VH was observed in all 74 eyes 5-50wk after initial treatment,with resolution of DME in 51 eyes 3-48wk after initial treatment.A newly developed epiretinal membrane was noted in one *** acuity significantly improved in 25 *** complications such as glaucoma,retinal detachment,or endophthalmitis were ***:The study suggests that the combination of PRP with IVC injections is an effective and safe modality for treating diabetic VH in patients with HR-PDR.

关键词： conbercept panretinal photocoagulation high-risk proliferative diabetic retinopathy vitreous hemorrhage

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Monocyte to High-density Lipoprotein Cholesterol Ratio as a Predictor of Nonalcoholic Fatty Liver Disease in Childhood Obesity

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当代医学科学（英文） 2024年第4期44卷 692-697页

作者： Jun-feng ZHANG Feng-qing CAI Xiu-cai ZHANG qing ye Department of Laboratory Medicine Children's HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China

Objective:Inflammation is involved in the development and progression of nonalcoholic fatty liver disease(NAFLD).The monocyte to high-density lipoprotein cholesterol ratio(MHR)has emerged as a marker for various inflammation-related *** aim of the present study was to investigate the association between the MHR and NAFLD in a population with childhood ***:Based on hepatic ultrasound,a total of 504 children with obesity(357 with NAFLD and 147 without NAFLD)were included in the *** correlation between the MHR and NAFLD risk factors was assessed by Pearson's and Spearman's *** stepwise logistic regression analyses were conducted to explore the association between the MHR and the risk of ***:The MHR in patients with NAFLD was significantly greater than that in patients without NAFLD[0.52(0.44-0.67)versus 0.44(0.34-0.57),P＜0.001].Multivariate stepwise logistic regression analysis demonstrated that the MHR[odds ratio(OR):1.033,95％confidence interval(CI):1.015-1.051;P＜0.001]was an independent predictor of NAFLD in childhood obesity patients,as were age(OR:1.205,95％CI:1.059-1.371;P=0.005],waist circumference[OR:1.037,95％CI:1.008-1.067;P=0.012],and alanine transaminase[OR:1.067,95％CI:1.045-1.089;P＜0.001].Additionally,MHR quartiles showed a significant positive association with the incidence of NAFLD after adjusting for potential confounding ***:The present study showed that the MHR may serve as an available and useful indicator of NAFLD in individuals with childhood obesity.

关键词： marker monocyte-to-high-density lipoprotein ratio nonalcoholic fatty liver disease obesity

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Color-polarization synergistic target detection method considering shadow interference

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Defence Technology（防务技术） 2024年第7期37卷 50-61页

作者： Bin Feng Jinpei Xiao Junchao Zhang Lin Li Yunlong Wu qing ye School of Automation Northwestern Polytechnical UniversityXi'an710072China School of Automation Central South UniversityChangsha410083China State Key Laboratory of Pulsed Power Laser Technology National University of Defense TechnologyHefei230037China

Aiming at the problem of shadow interference in UAV's ground reconnaissance,a color and polarization synergistic target detection method is proposed for anti-shadow interference,based on the influence of two physical characteristics(wavelength and polarization)under different illuminations.A valid fusion strategy is proposed via integrating two separate detection results on color and polarization ***,a local enhancement and recognition module(LER)is introduced to boost the *** on our built dataset,experimental results show that our method achieves mAPof 87.76%,and12.37%higher than that of color image and 14.68%higher than that of polarization image.

关键词： Electro-optical countermeasure Ground reconnaissance Color-polarization Shadow interference Target recognition

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Preparation and Reinforcement Adaptability of Jute Fiber Reinforced Magnesium Phosphate Cement Based Composite Materials

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Journal of Wuhan University of Technology(Materials Science) 2024年第4期39卷 999-1009页

作者：刘芯州郭远臣 WANG Rui XIANG Kai WANG Xue ye qing College of Civil Engineering Chongqing Three Gorges UniversityChongqing 404100China

To improve the brittleness characteristics of magnesium phosphate cement-based materials(MPC)and to promote its promotion and application in the field of structural reinforcement and repair,this study aimed to increase the toughness of MPC by adding jute fiber,explore the effects of different amounts of jute fiber on the working and mechanical properties of MPC,and prepare jute fiber reinforced magnesium phosphate cement-based materials(JFRMPC)to reinforce damaged *** improvement effect of beam performance before and after reinforcement was compared,and the strengthening and toughening mechanisms of jute fiber on MPC were explored through microscopic *** experimental results show that,as the content of jute fiber(JF)increases,the fluidity and setting time of MPC decrease continuously;When the content of jute fiber is 0.8%,the compressive strength,flexural strength,and bonding strength of MPC at 28 days reach their maximum values,which are increased by 18.0%,20.5%,and 22.6%compared to those of M0,*** beam strengthened with JFRMPC can withstand greater deformation,with a deflection of 2.3 times that of the unreinforced beam at *** strain of the steel bar is greatly reduced,and the initial crack and failure loads of the reinforced beam are increased by 192.1%and 16.1%,respectively,compared to those of the unreinforced *** JF added to the MPC matrix dissipates energy through tensile fracture and debonding pull-out,slowing down stress concentration and inhibiting the free development of cracks in the matrix,enabling JFRMPC to exhibit higher strength and better *** JF does not cause the hydration of MPC to generate new compounds but reduces the amount of hydration products generated.

关键词： magnesium phosphate cement jute fiber reinforcement of damaged beam flexural behavior

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A method for determining the complex refractive index dispersion of absorbing materials without thickness information

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Optoelectronics Letters 2024年第11期20卷 676-680页

作者： DENG Zhichao MEI Jianchun WANG Jin ye qing TIAN Jianguo Key Laboratory of Weak-Light Nonlinear Photonics Ministry of Education School of Physics and TEDA Applied Physics Nankai University

The complex refractive index dispersion(CRID) of absorbing materials is very important in many fields, especially in printing industry and medical research. However, due to their strong absorbing, CRID determination i... 详细信息

关键词： A

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Fine particle trace elements at a mountain site in southern China:Source identification,transport,and health risks

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Journal of Environmental Sciences 2024年第7期141卷 166-181页

作者： Jiaoping Xing Runping Ding Feifeng Chen Linyu Peng Wenhua Wang Xiaoyan Song qing ye Yuanqiu Liu Key Laboratory of State Forestry and Grassland Administration on Forest Ecosystem Protection and Restoration of Poyang Lake Watershed School of ForestryJiangxi Agricultural UniversityNanchang 330045China School of Resources and Materials Northeastern University at QinhuangdaoQinhuangdao 066004China College of Geosciences and Engineering North China University of Water Resources&Electric PowerZhengzhou 450046China

Trace elements in atmospheric particulate matter play a significant role in air quality,human health,and biogeochemical *** this study,the trace elements(Ca,Al,K,Fe,Na,Mg,Zn,Pb,Mn,Ti,Cu,Cr,Sr,Ni)in PM2.5samples collected at the summit of *** were analyzed to quantify their abundance,source,transport,and health *** the whole sampling period,the major trace elements was Ca,Al,and *** the trace metals with the lowest concentrations were Sr,Ni,Rb,and *** trace elements were influenced by air mass transport routes,exhibiting an increasing trend of crustal elements in the northwesterly airmass and anthropogenic elements(Zn,Mn,Cu,and Ni)in the easterly air *** dust,coal+biomass burning,vehicle emission,urban nitrate-rich+urban waste incineration emissions,and soil dust+industry emissions were common sources of PM2.5on *** air mass transport routes had various source contribution *** results indicate that trace elements at *** are influenced by regional anthropogenic emissions and monsoon-dominated trace element *** total resulting cancer risk value that these elements posed were below the acceptable risk value of 1×10^(-6),while the non-carcinogenic risk value(1.72)was higher than the safety level,suggesting that non-carcinogenic effects due to these trace elements inhalation were likely to *** emission and coal+biomass burning were the common dominant sources of non-cancer risks posed by trace elements at ***.

关键词： Trace elements Risk assessment Cluster analysis Source apportionment

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Detection of astrophysical gravitational wave sources by TianQin and LISA

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Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 123-163页

作者： Alejandro Torres-Orjuela Shun-Jia Huang Zheng-Cheng Liang Shuai Liu Hai-Tian Wang Chang-qing ye Yi-Ming Hu Jianwei Mei MOE Key Laboratory of Tian Qin Mission Tian Qin Research Center for Gravitational PhysicsSchool of Physics and AstronomyFrontiers Science Center for Tian QinGravitational Wave Research Center of CNSASun Yat-Sen University(Zhuhai Campus)Zhuhai 519082China Department of Physics The University of Hong KongHong Kong 999077China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing100871China

TianQin and LISA are space-based laser interferometer gravitational wave(GW)detectors planned to be launched in the *** detectors will detect low-frequency GWs around 10^(-2)Hz;however,Tian Qin is more sensitive to frequencies above this common sweet-spot while LISA is more sensitive to frequencies below 10^(-2)***,Tian Qin and LISA will be able to detect the same sources but with different accuracy depending on the source and its *** consider some of the most important astrophysical sources—massive black hole binaries,stellar-mass black hole binaries,double white dwarfs,extreme mass ratio inspirals,light and heavy intermediate mass ratio inspirals,as well as the stochastic gravitational background of astrophysical origin—that Tian Qin and LISA will be able to *** each of these sources,we analyze how far they can be detected(detection distance)and how well their parameters can be measured(detection accuracy)using a Fisher Matrix *** compare the results obtained by the three detection scenarios(Tian Qin alone,LISA alone,and joint detection by LISA and Tian Qin)highlighting the gains from joint detection as well as the contribution of Tian Qin and LISA to a combined study of astrophysical *** particular,we consider the different orientations,lifetimes,and duty cycles of the two detectors to explore how they can give a more complete picture when working together.

关键词： wave extreme stochastic

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Molecular Conformational Isomerization:An Efficient Way to Design Novel Emitters with Dual-Thermally Activated Delayed Fluorescence Characteristics and Their Optoelectronic and Bioimaging Applications

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CCS Chemistry 2024年第4期6卷 912-922页

作者： Yi-Zhong Shi Ya-Fang Xiao Hao Wu Shao-Li Zhang Xiao-Chun Fan ye Tian Chang-qing ye Kai Wang Jia Yu Chun-Sing Lee Xiao-Hong Zhang School of Materials Science and Engineering Suzhou University of Science and TechnologySuzhou 215009 Institute of Functional Nano and Soft Materials(FUNSOM) Joint International Research Laboratory of Carbon-Based Functional Materials and DevicesSoochow UniversitySuzhou 215123Jiangsu Center of Super-Diamond and Advanced Films(COSDAF) Department of ChemistryCity University of Hong KongHong Kong SAR School of Biomedical Engineering The Second Affiliated HospitalGuangzhou Medical UniversityGuangzhou 510260 Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Soochow UniversitySuzhou 215123Jiangsu Jiangsu Key Laboratory of Advanced Negative Carbon Technologies Soochow UniversitySuzhou 215123Jiangsu

Single-molecule luminophores with dual-thermally activated delayed fluorescence(TADF)properties are receiving increasing ***,how to achieve these goals requires more in-depth ***,we demonstrate a novel example emitter,10-(5-(2-(pyridin-3-yl)-[4,5′-bipyrimidin]-6-yl)pyridin-2-yl)-10Hphenoxazine(PmPy-PXZ),enabling dual-TADF properties due to its key feature of conformational *** a pyridine bridge can greatly reduce the steric hindrance and facilitate dual-stable conformations in the ground state,where the quasi-axial(QA)forms ***,unlike previously reported TADF molecules with dual confirmations,both theoretical and experimental measurements show that not only the quasi-equatorial(QE)forms but also the QA forms exhibit distinct TADF characteristics,which can be attributed to an additional higher reverse intersystem crossing *** is the first time that dual-TADF properties of single molecules have been achieved based on conformational *** applications in“self-doping”organic light-emitting diode and biomedical imaging have further been *** these results show the good potential of such dual-band TADF emitters based on molecular conformational isomerization.

关键词： dual-thermally activated delayed fluorescence conformational isomerization organic light-emitting diode biomedical imaging self-doping

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文化装置的建造与更新:党领导文艺的“经”与“权”

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文艺理论与批评 2024年第5期 21-31页

作者：叶青中央戏剧学院导演系

中国共产党领导文艺走过了百年历程,在新时代的历史节点重新理解党领导文艺的原则与其不同历史时期因地制宜的方针政策之间的辩证关系,十分必要。通过重新阐释列宁关于“巨大的社会民主主义机器的‘齿轮和螺丝钉’”的论述,以及马克思... 详细信息

中国共产党领导文艺走过了百年历程,在新时代的历史节点重新理解党领导文艺的原则与其不同历史时期因地制宜的方针政策之间的辩证关系,十分必要。通过重新阐释列宁关于“巨大的社会民主主义机器的‘齿轮和螺丝钉’”的论述,以及马克思列宁主义的中国化,可以看到文艺的“党性原则”,意指把关乎社会总体的新文化与社会主体的生成过程、社会主义国家建构过程绑定在一起,而其内含的“经”与“权”的辩证运动的结构,指向了国家机器及其新的文化装置的自我更新的问题。“中国式现代化”的概念则从总体性维度,为综合党领导文艺的百年经验提供了理论视野。

关键词： “齿轮和螺丝钉” 文化装置 “经”与“权” 中国式现代化

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违法立案的检察监督机制研究

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国家检察官学院学报 2024年第1期32卷 53-68页

作者：叶青华东政法大学刑事法学院

立案作为刑事诉讼的启动程序,决定着案件是否被纳入刑事追诉的范围。加强和完善刑事立案监督工作,对于及时发现和纠正违法立案现象,促进严格公正执法,维护司法公正,确保国家法律的统一正确实施,具有重要价值。司法实践中,因立法缺失、... 详细信息

立案作为刑事诉讼的启动程序,决定着案件是否被纳入刑事追诉的范围。加强和完善刑事立案监督工作,对于及时发现和纠正违法立案现象,促进严格公正执法,维护司法公正,确保国家法律的统一正确实施,具有重要价值。司法实践中,因立法缺失、程序不畅、组织保障不足,导致监督机制失衡,对违法立案的监督具有明显滞后性。研究如何修订相关规范、拓宽案件线索的来源渠道、规范化运行监督撤案程序及提供科学有效的组织保障,对建立健全违法立案的检察监督机制大有裨益。

关键词：违法立案检察监督监督机制

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