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A gelatin-based artificial SEI for lithium deposition regulation and polysulfide shuttle suppression in lithium-sulfur batteries

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journal of Energy Chemistry 2021年第1期30卷 310-317,I0010页

作者： Naseem Akhtar Xiaogang Sun Muhammad yasir Akram Fakhar Zaman Weikun Wang Anbang Wang Long Chen Hao Zhang Yuepeng Guan Yaqin Huang Beijing Key Laboratory of Electrochemical Process and Technology for Materials Key Laboratory of Biomedical Materials of Natural MacromoleculesMinistry of EducationBeijing Advanced Innovation Center for Soft Matter Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029China Research Institute of Chemical Defense Beijing 100191China

Lithium-sulfur(Li-S) battery is one of the best candidates for the next-generation energy storage system due to its high theoretical capacity(1675 mA h-1),low cost and environment ***,lithium(Li) dendrites formation and polysulfide shuttle effect are two major challenges that limit the commercialization of Li-S *** we design a facile bifunctional interlayer of gelatin-based fibers(GFs),aiming to protect the Li anode surface from the dendrites growth and also hinder the polysulfide shuttle *** reveal that the 3D structural network of GFs layer with abundant polar sites helps to homogenize Li-ion flux,leading to uniform Li-ion ***,the polar moieties also immobilize the lithium polysulfides and protect the Li metal from the *** a result,the anodeprotected batteries have shown significantly enhanced performance.A high coulombic efficiency of 96% after 160 cycles has been achieved in the Li-Cu half *** Li-Li symmetric cells exhibit a prolonged lifespan for 800 h with voltage hysteresis(10 mV).With the as-prepared GFs layer,the Li-S battery shows approximately 14% higher capacity retention than the pristine battery at 0.5 C after 100 *** work presents that this gelatin-based bi-functional interlayer provides a viable strategy for the manufacturing of advanced Li-S batteries.

关键词： Bifunctional layer Gelatin-based fibers Shuttle effect Artificial SEI Lithium-sulfur battery

Xinjiang Blossoming Under Rule of Law

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Beijing Review 2024年第37期67卷 20-21页

作者： yasir Habib Khan Pakistan's Institute of International Relations and Media Research

Contrary to the West's false and misleading information regarding repression of Uygur Muslims in Xinjiang Uygur Autonomous Region,Islam is blossoming with all its religious colors and traditional fashion under the *** is an eye-witness observation of a nine-member Pakistani media delegation that visited Urumqi and Yining cities from August 19 to *** delegation visited the Xinjiang Counter-Terrorism and Counter-Extremism Exhibition,Xinjiang Islamic Institute(XII),Xinjiang Art Theater Muqam Art Troupe,Xinjiang International Grand Bazaar,Shaanxi Mosque and other places.

关键词： Xinjiang delegation religious

The IMEC and the BRI:Friends or Foes?

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Beijing Review 2023年第44期66卷 20-21页

作者： yasir Habib Khan Institute of International Relations&Media Research in Pakistan

In an attempt to parallel the Belt and Road Initiative(BRI),a China-proposed initiative to enhance global connectivity along and beyond the ancient Silk Road routes that embodies inclusiveness,openness and shared dividends,the India-Middle East-Europe Economic Corridor(IMEC),announced at the Group of 20(G20)Leaders'Event on Partnership for Global Infrastructure and Investment on September 9,lacks the global aura,scale,resources and networks to meet the world's current and future needs.

关键词： Middle BRI connectivity

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纳秒脉冲电场诱导B16细胞凋亡的机制研究

电子科技大学学报 2020年第6期49卷 949-954页

作者：饶鑫陈晓东周俊刘贻尧 yasir Alfadhl 电子科技大学电子科学与工程学院成都611731 玛丽女王大学电子工程与计算机科学学院伦敦E14NS 电子科技大学生命科学与技术学院成都610054

纳秒脉冲电场具有诱导癌细胞凋亡、抑制肿瘤生长和诱导抗肿瘤免疫的作用。由于纳秒脉冲诱导治疗涉及的通路过多和常规检测特异性生物标志物技术的局限性,其凋亡机制尚未达成共识且暂时没有高效的研究方法。为了深入研究凋亡机制,该文利... 详细信息

纳秒脉冲电场具有诱导癌细胞凋亡、抑制肿瘤生长和诱导抗肿瘤免疫的作用。由于纳秒脉冲诱导治疗涉及的通路过多和常规检测特异性生物标志物技术的局限性,其凋亡机制尚未达成共识且暂时没有高效的研究方法。为了深入研究凋亡机制,该文利用蛋白芯片技术和富集分析技术研究了纳秒脉冲电场诱导小鼠黑色素瘤B16细胞的凋亡机制,并推导了纳秒脉冲诱导治疗的凋亡机制。该研究方法对于有此类靶点数目众多的机制研究具有独特的优势,可为设计未来的纳秒脉冲诱导治疗方案提供参考,优化最佳的脉冲参数或增强/抑制特定的分子以获得最佳治疗效果。

关键词：蛋白芯片细胞凋亡富集分析纳秒脉冲电场

Body to body network using zigbee

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Body to body network using zigbee

The association between mycotic pneumonia and neonatal septicemia

2011 IEEE 3rd International Conference on Communication Software and Networks(ICCSN 2011)

作者： Muhammad yasir Air Ammar j Malik University Islamabad Pakistan University of Engineering and Technology Taxila Pakistan

Before zigbee most of the wireless protocols and standards were develop for high date rate and higher bandwidth and there were no considerations on the power consumption as the application needed to support longer distances and speed but this kind of technology was not efficient when the data which needed to be transmitted was of very small size and the distance was also not very *** solution could have been the use of Bluetooth but because of its greater joining time and more power consumption as compared with zigbee it was not *** will use zigbee modules for transmitting data between two cell phones that are presently located in a pan that will eliminate the use of GSM （Global System for Mobile Communications）provider and hence cut the cost that is associated with it.

关键词： Zigbee Wireless Sensor Networks IEEE 802.15.4 jenic Modules Infrastructure less communication

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journal of Biosafety and Biosecurity 2024年第3期6卷 137-141页

作者： Salman Khalid Salman yasir Mufeed Abdulateef Sawsan Qahtan Taha Al-Quhli Department of Microbiology College of MedicineUniversity of AnbarIraq

Background:Candida species are the fourth most common etiological agents of late-onset infection in the neonatal intensive care unit(NICU)and are responsible for considerable morbidity and ***:From November 2023 to February 2024,we investigated the association of mycotic pneumonia with septicemia in 60 neonates,and their roles of mycotic pneumonia in the morbidity and mortality of neonates in two NICUs in the Al-Ramadi Teaching Hospital for Maternity and ***:All infants in this study had been diagnosed with septicemia and treated with empirical antimicrobial *** early morning nasogastric tube(NG-tube)was used to collect swallowed sputum by suction for culture and sensitivity ***:The average white blood count for the neonates was 8547±5884.5 cells/mm^(2).The mean C-reactive protein was 39.3±26 mg/l,the mean serum albumin was 2.9±0.2 g/dl and the positive bacterial blood culture was 28(46.7%).9(15%)neonates died during the study *** NG-tube culture identified fungal growth in all *** these,49(81.6%)were identified as Candida albicans,6(10%)as Candida tropicalis,and 5(8.3%)as Cryptococcus *** bacterial culture results from the NG-tube samples identified 13(21.6%)patients with gram-positive bacteria and 47(78.3%)with gram-negative ***:We found a prevalence of Candida *** neonates in addition to microbial oxygen tube contamination,indicating a biosafety breach in the neonatal *** infection requires global attention as a probable cause of respiratory failure in neonatal septicemia.

关键词： Neonatal sepsis Mycotic pneumonia Anti-Mycotic therapy NG-tube culture Nosocomial infections

Additive manufacturing of sustainable biomaterials for biomedical applications

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Asian journal of Pharmaceutical Sciences 2023年第3期18卷 1-36页

作者： Zia Ullah Arif Muhammad yasir Khalid Reza Noroozi Mokarram Hossain Hao Tian Harvey Shi Ali Tariq Seeram Ramakrishna Rehan Umer Department of Mechanical Engineering University of Management&Technology LahoreSialkot Campus 51041Pakistan Department of Aerospace Engineering Khalifa University of Science and TechnologyAbu Dhabi 127788United Arab Emirates School of Mechanical Engineering Faculty of EngineeringUniversity of TehranTehranIran Zienkiewicz Centre for Computational Engineering(ZCCE) Faculty of Science and EngineeringSwansea UniversitySwansea SA18ENUK Department of Mechanical&Materials Engineering Western UniversityOntario N6A 3K7Canada Department of Mechanical Engineering Center for Nanofibers and NanotechnologyNational University of Singapore119260Singapore

Biopolymers are promising environmentally benign materials applicable in multifarious *** are especially favorable in implantable biomedical devices thanks to their excellent unique properties,including bioactivity,renewability,bioresorbability,biocompatibility,biodegradability and *** manufacturing(AM)is a flexible and intricate manufacturing technology,which is widely used to fabricate biopolymer-based customized products and structures for advanced healthcare ***-dimensional(3D)printing of these sustainable materials is applied in functional clinical settings including wound dressing,drug delivery systems,medical implants and tissue *** present review highlights recent advancements in different types of biopolymers,such as proteins and polysaccharides,which are employed to develop different biomedical products by using extrusion,vat polymerization,laser and inkjet 3D printing techniques in addition to normal bioprinting and four-dimensional(4D)bioprinting *** also incorporates the influence of nanoparticles on the biological and mechanical performances of 3D-printed tissue scaffolds,and addresses current challenges as well as future developments of environmentally friendly polymeric materials manufactured through the ***,there is a need for more focused research on the adequate blending of these biodegradable biopolymers for achieving useful results in targeted biomedical *** envision that biopolymer-based 3D-printed composites have the potential to revolutionize the biomedical sector in the near future.

关键词： 3D printing Biopolymers Biomedical Tissue engineering Sustainable biomaterials Additive manufacturing

Elucidating the clinical and immunological value of m6A regulatormediated methylation modification patterns in adrenocortical carcinoma

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Oncology Research 2023年第5期31卷 819-831页

作者： WENHAO XU HAOMING LI yasir HAMEED MOSTAFA A.ABDEL-MAKSOUD SAEEDAH MUSAED ALMUTAIRI AYMAN MUBARAK MOHAMMED AUFY WAEL ALTURAIKI ABDULAZIZ j.ALSHALANI AYMAN M.MAHMOUD CHEN LI Department of Urology Urological Surgery Research InstituteFirst Affiliated HospitalArmy Medical University(Third Military Medical University)ChongqingChina Department of Urology Affiliated Hospital of Guilin Medical UniversityGuilinChina Department of Applied Biological Sciences Tokyo University of ScienceTokyoJapan Department of Botany and Microbiology College of ScienceKing Saud UniversityRiyadhSaudi Arabia Department of Pharmaceutical Sciences Division of Pharmacology and ToxicologyUniversity of ViennaViennaAustria Department of Medical Laboratory Sciences College of Applied Medical SciencesKing Saud UniversityRiyadhSaudi Arabia Department of Life Sciences Faculty of Science and EngineeringManchester Metropolitan UniversityManchesterUK Department of Biology ChemistryPharmacyFree University of BerlinBerlinGermany

N6-methyladenosine methylation(m6A)is a common type of epigenetic alteration that prominently affects the prognosis of tumor ***,it is unknown how the m6A regulator affects the tumor microenvironment(TME)cell infiltration in adrenocortical carcinoma(ACC)and how it affects the prognosis of ACC patients *** m6A alteration patterns of 112 ACC patients were evaluated,furthermore,the association with immune infiltration cell features was *** unsupervised clustering method was applied to typify the m6A alteration patterns of ACC *** principal component analysis(PCA)technique was taken to create the m6A score to assess the alteration pattern in specific *** found two independent patterns of m6A alteration in ACC *** TME cell infiltration features were significantly in accordance with phenotypes of tumor immune-inflamed and immune desert in both *** m6Ascore also served as an independent predictive factor in ACC *** somatic copy number variation(CNV)and patients prognosis can be predicted by m6A alteration ***,the ACC patients with high m6A scores had better overall survival(OS)and higher efficiency in immune checkpoint blockade *** work demonstrated the significance of m6A alteration to the ACC patients *** individual m6A alteration patterns analysis might contribute to ACC patients prognosis prediction and immunotherapy choice.

关键词： m6A Tumor microenvironment Adrenocortical carcinoma Immunotherapy Prognosis

Prediction of promiscuous T-cell epitopes in the Zika virus polyprotein:An in silico approach

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Asian Pacific journal of Tropical Medicine 2016年第9期9卷 822-828页

作者： Hamza Dar Tahreem Zaheer Muhammad Talha Rehman Amjad Ali Aneela javed Gohar Ayub Khan Mustafeez Mujtaba Babar yasir Waheed Atta-ur-Rahman School of Applied Biosciences(ASAB) National University of Sciences and Technology Shifa College of Pharmaceutical Sciences Shifa Tameer-e-Millat University Foundation University Medical College Foundation University Islamabad

Objective:To predict immunogenic promiscuous T-cell epitopes from the polyprotein of the Zika virus using a range of bioinformatics *** date,no epitope data are available for the Zika virus in the IEDB ***:We retrieved nearly 54 full length polyprotein sequences of the Zika virus from the NCBI database belonging to different outbreaks.A consensus sequence was then used to predict the promiscuous T cell epitopes that bind MHC 1 and MHC II alleles using Propred1 and Propred immunoinformatic algorithms *** antigencity predicted score was also calculated for each predicted epitope using the Vaxi jen 2.0 ***:By using Pro Pred1,23 antigenic epitopes for HLA class I and 48 antigenic epitopes for HLA class II were predicted from the consensus polyprotein sequence of Zika *** greatest number of MHC class I binding epitopes were projected within the NS5(21%),followed by Envelope(17%).For MHC class II,greatest number of predicted epitopes were in NS5(19%) followed by the Envelope,NS1 and NS2(17% each).A variety of epitopes with good binding affinity,promiscuity and antigenicity were predicted for both the HLA ***:The predicted conserved promiscuous T-cell epitopes examined in this study were reported for the first time and will contribute to the imminent design of Zika virus vaccine candidates,which will be able to induce a broad range of immune responses in a heterogeneous HLA ***,our results can be verified and employed in future efficacious vaccine formulations only after successful experimental studies.

关键词： Zika Virus B-Cell Epitopes T-Cell Epitopes Vaccine Antigenicity