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Development of methods for detecting the fate of mesenchymal stem cells regulated by bone bioactive materials

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Bioactive Materials 2021年第3期6卷 613-626页

作者： Jiang Le Liu Zhongqun Wang Zhaoyan Su Yijun Wang Yingjin wei yaojie Jiang Yanan Jia Zhanrong Ma Chunyang Gang Fangli Xu Nan Zhao Lingyun Wang Xiumei Wu Qiong Lu Xiong Sun Xiaodan State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084People's Republic of China Key Laboratory of Advanced Materials of Ministry of Education of China School of Materials Science and EngineeringTsinghua UniversityBeijing100084People's Republic of China Key Lab of Advanced Technologies of Materials of Ministry of Education School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu610031People's Republic of China MOE Key Laboratory of Bioinformatics Tsinghua UniversityBeijing100084People's Republic of China Center for Synthetic and Systems Biology Tsinghua UniversityBeijing100084People's Republic of China School of Life Sciences Tsinghua UniversityBeijing100084People's Republic of China

The fate of mesenchymal stem cells(MSCs)is regulated by biological,physical and chemical *** in biotechnology and materials science promoted the occurrence of bioactive materials which can provide physical and chemical signals for MSCs to regulate their *** order to design and synthesize materials that can precisely regulate the fate of MSCs,the relationship between the properties of materials and the fate of mesenchymal stem cells need to be clarified,in which the detection of the fate of mesenchymal stem cells plays an important *** the past 30 years,a series of detection technologies have been developed to detect the fate of MSCs regulated by bioactive materials,among which high-throughput technology has shown great advantages due to its ability to detect large amounts of data at one *** this review,the latest research progresses of detecting the fate of MSCs regulated by bone bioactive materials(BBMs)are systematically reviewed from traditional technology to high-throughput technology which is emphasized ***,current problems and the future development direction of detection technologies of the MSCs fate regulated by BBMs are *** aim of this review is to provide a detection technical framework for researchers to establish the relationship between the properties of BMMs and the fate of MSCs,so as to help researchers to design and synthesize BBMs better which can precisely regulate the fate of MSCs.

关键词： Bone bioactive materials High-throughput technology Transcriptomics Single cell RNA-seq Proteomics

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PLC在液压机控制系统中的应用

可编程控制器与工厂自动化 2012年第2期 83-85页

作者：韦耀杰中国矿业大学信息与电气工程学院

本文提出了液压机压力闭环控制的电气系统,实现了液压机压力的精确控制。该系统在原有开环控制基础上进行了改进探讨,目的在于解决传统的开关量控制存在的精度低、可靠性不高、性能不稳定等问题。该系统是一个实用的控制系统,目前,已经... 详细信息

本文提出了液压机压力闭环控制的电气系统,实现了液压机压力的精确控制。该系统在原有开环控制基础上进行了改进探讨,目的在于解决传统的开关量控制存在的精度低、可靠性不高、性能不稳定等问题。该系统是一个实用的控制系统,目前,已经得到广泛应用。

关键词： PLC PID 液压机控制系统

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基于电容中分式有源电力滤波器的研究

变频器世界 2015年第2期 37-40页

作者：韦耀杰平煤股份田庄选煤厂

针对三相四线制系统中谐波和无功功率统一补偿的问题,设计了一种电容中分式并联型有源电力滤波器。采用基于瞬时无功功率理论的方法检测谐波,三维空间矢量(3D-SVPWM)的方法产生补偿电流。通过搭建Matlab/Simulink仿真平台,验证了基于电... 详细信息

针对三相四线制系统中谐波和无功功率统一补偿的问题,设计了一种电容中分式并联型有源电力滤波器。采用基于瞬时无功功率理论的方法检测谐波,三维空间矢量(3D-SVPWM)的方法产生补偿电流。通过搭建Matlab/Simulink仿真平台,验证了基于电容中分式三相四线制有源电力滤波器良好的补偿性能。

关键词：有源滤波器谐波检测三相四线制空间矢量

基于DEM模拟的筒仓卸料过程瞬时拱影响因素分析

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包装与食品机械 2024年第4期42卷 56-66页

作者：韦熙周甲伟徐耀杰华北水利水电大学机械学院郑州450045

为探究大豆在筒仓卸料过程的瞬时拱形成条件及各因素的影响规律,阐明大豆在筒仓内的流变特性,采用离散元方法(DEM),以大豆在筒仓内的卸料过程为对象,通过改变筒仓的半锥角、开口直径、颗粒间摩擦系数、物料密实度等参数,分别进行模拟仿... 详细信息

为探究大豆在筒仓卸料过程的瞬时拱形成条件及各因素的影响规律,阐明大豆在筒仓内的流变特性,采用离散元方法(DEM),以大豆在筒仓内的卸料过程为对象,通过改变筒仓的半锥角、开口直径、颗粒间摩擦系数、物料密实度等参数,分别进行模拟仿真。结果表明,半锥角为30°,35°,45°时,最大压力值分别为2390.76,2289.53,2540.9 Pa;开口直径为50,60,70 mm时,卸料时间分别为103,62,40 s;摩擦系数设置为0.6,0.7,0.8时,卸料时间分别为61.9,64.9,67.2 s;密实度设置为500,750,1000 mm时,最大质量流量分别为0.44,0.50,0.67 kg/s。研究为更精确地寻求其他散料食品在筒仓卸料过程的流变特性提供参考。

关键词：离散元方法筒仓卸料瞬时拱影响因素

基于模糊控制的分组投切无功补偿控制器的研究与设计

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煤矿机电 2013年第1期34卷 25-30,33页

作者：郝军营关瑞芳韦耀杰中平能化集团天成环保工程有限公司河南平顶山467000 平煤集团田庄选煤厂河南平顶山467013

依据模糊控制理论,设计以STM32F103VET6单片机为核心,开发了基于模糊控制理论的分组投切无功补偿装置的控制器。控制器采用电压无功复合投切判据,既能有效克服了以功率因数单一元素作为投切判据的控制方式下的投切震荡问题,又可提高无... 详细信息

依据模糊控制理论,设计以STM32F103VET6单片机为核心,开发了基于模糊控制理论的分组投切无功补偿装置的控制器。控制器采用电压无功复合投切判据,既能有效克服了以功率因数单一元素作为投切判据的控制方式下的投切震荡问题,又可提高无功补偿装置的可靠性和稳定性。

关键词：无功补偿分组投切模糊控制

Corrigendum to“Development of methods for detecting the fate of mesenchymal stem cells regulated by bone bioactive materials”[***.6(3)(2021)613-626]

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生物活性材料(英文) 2023年第6期24卷 251-251页

作者： Le Jiang Zhongqun Liu Zhaoyan Wang Yijun Su Yingjin Wang yaojie wei Yanan Jiang Zhanrong Jia Chunyang Ma Fangli Gang Nan Xu Lingyun Zhao Xiumei Wang Qiong Wu Xiong Lu Xiaodan Sun State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084PR China Key Laboratory of Advanced Materials of Ministry of Education of China School of Materials Science and EngineeringTsinghua UniversityBeijing100084PR China Key Lab of Advanced Technologies of Materials of Ministry of Education School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu610031PR China MOE Key Laboratory of Bioinformatics Tsinghua UniversityBeijing100084PR China Center for Synthetic and Systems Biology Tsinghua UniversityBeijing100084PR China School of Life Sciences Tsinghua UniversityBeijing100084PR China

The authors regret that the last name and first name of all authors are reversed in the original *** correct writing is as follows:Le Jiang,a,b#;Zhongqun Liu,a,b#;Zhaoyan Wang,d,e,f;Yijun Su,a,b;Yingjin Wang,a,b;yaojie wei,a,b;Yanan Jiang,c;Zhanrong Jia,c;Chunyang Ma,a,b;Fangli Gang,a,b;Nan Xu,a,b;Lingyun Zhao,a,b;Xiumei Wang,a,b;Qiong Wu,d,e,f;Xiong Lu,c,*and Xiaodan Sun,a,b,**** Key Laboratory of New Ceramics and Fine Processing,School of Materials Science and Engineering,Tsinghua University,Beijing 100084,People’s Republic of China;*** Laboratory of Advanced Materials of Ministry of Education of China,School of Materials Science and Engineering,Tsinghua University,Beijing 100084,People’s Republic of China;*** Lab of Advanced Technologies of Materials of Ministry of Education,School of Materials Science and Engineering,Southwest Jiaotong University,Chengdu 610031,People’s Republic of China *** Key Laboratory of Bioinformatics,Tsinghua University,Beijing,100084,People’s Republic of China *** for Synthetic and Systems Biology,Tsinghua University,Beijing,100084,People’s Republic of China *** of Life Sciences,Tsinghua University,Beijing,100084,People’s Republic of China.

关键词： reversed Republic Chengdu

生物质颗粒燃料取暖的环境健康效益及经济成本分析

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生态环境学报 2024年第6期33卷 927-934页

作者：魏代晓门亚泰李尧捷徐铭忆蔡文秀沈国锋烟台市建筑设计研究股份有限公司山东烟台264003 超低能耗绿色建筑山东省工程研究中心山东烟台2640031 北京大学城市与环境学院北京100871 北京大学碳中和研究院北京100871

清洁取暖是解决区域空气污染,提升居民生活质量的重要举措。充分考虑不同地区资源禀赋和社会经济发展条件差异,实施因地制宜的清洁取暖政策,发挥生物质资源碳中性优势,在适宜的地区开展生物质清洁取暖有望取得减污降碳协同增效,但目前... 详细信息

清洁取暖是解决区域空气污染,提升居民生活质量的重要举措。充分考虑不同地区资源禀赋和社会经济发展条件差异,实施因地制宜的清洁取暖政策,发挥生物质资源碳中性优势,在适宜的地区开展生物质清洁取暖有望取得减污降碳协同增效,但目前缺乏相关实证研究。针对生物质清洁取暖,开展了实地监测与问卷调查,量化评估了其环境健康效益和经济可行性。研究表明,研究地区农村进行生物质颗粒取暖改造后,取暖能源的利用效率显著上升,冬季室内温度更适宜,而室内PM_(2.5)污染水平中位数为74μg∙m^(−3),相较未改造下降了25%,而由于室内排放的细颗粒物减少,环境污染物浓度也有所降低。尽管生物质颗粒燃料的单位质量热值普遍小于散煤,燃料使用量相较改造前有所上升,但由于生物质颗粒燃料PM_(2.5)的排放因子显著低于散煤,且炉灶改造后燃料利用率上升,改造后取暖燃烧过程中直接排放的PM_(2.5)相较改造前降低了54%。除PM_(2.5)外,二氧化碳与其他污染物排放也下降了3%-37%。根据模拟结果,进行取暖改造后,平均每年每户家庭取暖活动可减少约3 kg的初级PM_(2.5)排放与37 kg的CO_(2)排放,有效支持了清洁取暖政策与减污降碳战略。根据经济可行性分析,改造后农户取暖成本并未增加,相较“煤改电”或“煤改气”路径,研究地区进行生物质颗粒取暖具有更高的可行性,对政府与农村居民的负担较低。综上,根据实地资源禀赋推广生物质清洁取暖可取得显著的环境效益和气候效益,且具有较高的经济可行性。

关键词：生物质清洁取暖细颗粒物污染物排放环境效益经济可行性

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直升机尾传动轴弹击损伤数值模拟研究

振动与冲击 2024年第13期43卷 324-332,340页

作者：未雷林瑶洁吴汪箭陈蔚芳王希朱如鹏王旦南京航空航天大学直升机传动技术国家级重点实验室南京210016 中国航发湖南动力机械研究所直升机传动技术国家级重点实验室湖南株洲412002

面向直升机尾传动轴抗弹击设计,开展了不同因素影响下尾传动轴弹击损伤规律数值模拟研究。基于有限元仿真软件建立了尾传动轴弹击损伤数值仿真模型,并通过弹击试验验证模型的可靠性。进而基于经验证的数值仿真模型,分析了偏移量和入射... 详细信息

面向直升机尾传动轴抗弹击设计,开展了不同因素影响下尾传动轴弹击损伤规律数值模拟研究。基于有限元仿真软件建立了尾传动轴弹击损伤数值仿真模型,并通过弹击试验验证模型的可靠性。进而基于经验证的数值仿真模型,分析了偏移量和入射角两个典型参数对尾传动轴弹击损伤的影响规律。分析结果表明:尾传动轴弹击损伤程度随着子弹偏移量及入射角的增大,呈现先增大后减小的趋势,在切边位置、入射角为75°工况下尾传动轴弹击损伤最为严重。在此基础上,进一步研究了摩擦因数、子弹入射速度、尾传动轴转速、子弹偏航角四个弹靶参数对尾传动轴弹击损伤的影响规律。研究结果表明:摩擦因数对尾传动轴弹击损伤影响较小,尾传动轴转速、子弹入射速度和子弹偏航角均对尾传动轴弹击损伤有较大影响。

关键词：直升机尾传动轴弹击损伤数值模拟

Microstructures and Mechanical Properties of the TiC/CM247LC Nickel-Based Composite Fabricated by Selective Laser Melting:Effect of Heat Treatment

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Acta Metallurgica Sinica(English Letters) 2023年第12期36卷 1936-1946页

作者： Yuting Lv yaojie Liu Zhe Zhang Qiang Zhang Hongyao Yu Rui Wang Guangbao Sun Guijiang wei College of Mechanical and Electronic Engineering Shandong University of Science and TechnologyQingdao 266590China Gaona Aero Material Co. Ltd.Beijing 100094China Beijing Key Laboratory of Advanced High Temperature Materials Central Iron and Steel Research InstituteBeijing 100094China Shanghai Key Laboratory of Advanced High-Temperature Materials and Precision Forming Shanghai Jiao Tong UniversityShanghai 200240China Affiliated Hospital of Youjiang Medical University forNationalities Baise 533000China

In this study,TiC/CM247LC nickel-based composite was successfully prepared by selective laser melting,then was heat treated at a solid solution temperature of 1260℃and different aging temperature of 840℃,870℃,900℃and 930℃*** of aging temperatures on the microstructures and mechanical properties were systematically *** results show that the microstructures of all the heat treated samples are composed ofγmatrix,carbides andγ′***γgrains remain a columnar shape after treatments,but the size ofγ′phase grows up gradually with the increasing aging *** composite treated at an aging temperature of 870℃exhibits the best mechanical properties with the tensile strength of 1073 MPa,yield strength of 1004 MPa and elongation of 7.57%.The plastic deformation and strengthening mechanisms of heat treated composite were systematically investigated.

关键词： Selective laser melting Heat treatment Nickel-based composite Microstructures Mechanical properties