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Successful management of severe hypoglycemia induced by total parenteral nutrition in patients with hepatocellular injury: Three cases reports

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World Journal of Clinical Cases 2024年第1期12卷 157-162页

作者： ling-Zhi Fang Hui-Xin Jin Na Zhao Yu-pei Wu Ying-Qin Shi Department of Pharmacy Hebei Key Laboratory of Clinical PharmacyHebei General HospitalShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Glucose imbalance is common in total parenteral nutrition(TPN).Hypoglycemia seems to be less frequent than hyperglycemia,but it influences the clinical outcome to a greater ***,it should be effectively prevented and ***,there is no relevant report on how to treat hypoglycemia caused by TPN in patients with liver cell *** SUMMARY We present three patients with liver cell injury who developed severe hypo-glycemia during or after TPN *** causes of severe hypoglycemia and glucose-raising strategies were *** to the physiological charac-teristics of the hepatocellular injury,the ratio of nutrition components prescribed in TPN was appropriately adjusted for the three *** simultaneously reduced the dose of insulin and fat emulsion,and increased the dose of glucose in *** blood glucose level was restored to normal range and clinical symptoms were *** When hypoglycemia occurs during or after TPN in patients with hepatocellular injury,physicians need to simultaneously reduce insulin and fat emulsion,and increase glucose,and correct severe hypoglycemia in time to reduce its adverse consequences.

关键词： Total parenteral nutrition Hepatocellular injury Severe hypoglycemia Treatment Causes Case report

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两种抗旱剂对大叶黄杨光合特性的耦合效应

应用生态学报 2007年第3期18卷 514-518页

作者：王勇杨培岭任树梅中国农业大学水利与土木工程学院

通过田间试验,研究了FA旱地龙和BGA两种新型抗旱剂对大叶黄杨叶片光合特性的耦合影响.结果表明:FA旱地龙和BGA均能使大叶黄杨叶片的气孔导度(gs)和蒸腾速率(Tr)缩小,净光合速率(Pn)和Pn/Tr增加;受BGA影响,FA旱地龙对未施用BGA叶片gs和T... 详细信息

通过田间试验,研究了FA旱地龙和BGA两种新型抗旱剂对大叶黄杨叶片光合特性的耦合影响.结果表明:FA旱地龙和BGA均能使大叶黄杨叶片的气孔导度(gs)和蒸腾速率(Tr)缩小,净光合速率(Pn)和Pn/Tr增加;受BGA影响,FA旱地龙对未施用BGA叶片gs和Tr的抑制作用比对施用BGA叶片的抑制作用显著;FA旱地龙对未施用BGA叶片的Pn和Pn/Tr有促进作用,对施用BGA叶片的Pn和Pn/Tr有抑制作用;FA旱地龙对未施用BGA叶片的作用时间明显比对施用BGA叶片的作用时间长.BGA对FA旱地龙作用效果的影响原因可能与BGA和植物本身的光合特性有关.未施用BGA大叶黄杨适宜的FA旱地龙喷施浓度为2g.L-1,FA旱地龙不适宜于施用BGA的大叶黄杨.

关键词：抗旱剂光合特性耦合影响大叶黄杨作用时间

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Chlorogenic acid supported strontium polyphenol networks ensemble microneedle patch to promote diabetic wound healing

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Chinese Chemical Letters 2024年第8期35卷 491-497页

作者： peizhe Li Qiaoling Liu Mengyu pei Yuci Gan Yan Gong Chuchen Gong pei Wang Mingsong Wang Xiansong Wang Da-Peng yang Bo Liang Guangyu Ji Research Institute of Plastic Surgery Weifang Medical UniversityWeifang 261000China The Second Affiliated Hospital of Fujian Medical University Quanzhou 362000China Department of Thoracic surgery Shanghai Key Laboratory of Tissue EngineeringShanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China The Third Affiliated Hospital of Xinxiang Medical University Institutes of Health Central PlainClinical Medical Center of Tissue Engineering and RegenerationXinxiang Medical UniversityXinxiang 453003China School of Rehabilitation Science and Engineering University of Health and Rehabilitation SciencesQingdao 266024China

Delayed or non-healing of diabetic wounds is a significant complication,often attributed to high glucose-induced M1 macrophage accumulation,impaired angiogenesis,and reactive oxygen species(ROS)*** this,we introduced a strontium polyphenol network microneedle patch(SrC-MPNs@MN-PP)for percutaneous drug *** patch,formulated with polymer poly(γ-glutamic acid)(γ-PGA)and epsilon-poly-l-lysine(ε-PLL),incorporates strontium polyphenol networks(SrC-MPNs).The release of chlorogenic acid(CGA)from SrC-MPNs not only neutralizes ROS,but strontium ions also foster ***,SrC-MPNs@MN-PP can ameliorate the diabetic wound microenvironment and expedite healing.

关键词： Chlorogenic acid Strontium Microneedle patch Strontium polyphenol network Exudate absorption Diabetic wound healing

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Wideband chaos generation using a VCSEL with intensity modulation optical injection for random number generation

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Science China(Information Sciences) 2024年第6期67卷 457-458页

作者： Yu HUANG Shuangquan GU Yuhang FENG Yigong yang Shuiying XIANG pei ZHOU Nianqiang LI School of Optoelectronic Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University State Key Laboratory of Integrated Service Networks Xidian University Key Lab of Advanced Optical Manufacturing Technologies of Jiangsu Province & Key Lab of Modern Optical Technologies of Education Ministry of China Soochow University

Physical random numbers have been widely used in modern network society,such as the generation of cryptographic keys for classical and quantum cryptography systems[1].Among the many sources of physical entropy,chaotic semiconductor lasers have attracted wide attention due to their desired characteristics including larger bandwidth,low cost,and monolithic integration[2].

关键词： Optical signal processing

Trans-PRK for recurrent epithelial corneal erosion induced by cooking oil accidentally after EVO ICL

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1953-1956页

作者： Yong Ma Wan-Ru Shi ling-ling Niu pei-Jun Yao Xiao-Ying Wang Xing-Tao Zhou Jing Zhao Eye Institute and Department of Ophthalmology Eye&ENT HospitalFudan UniversityShanghai 200031China Key Laboratory of Myopia and Related Eye Diseases NHCShanghai 200031China Key Laboratory of Myopia and Related Eye Diseases Chinese Academy of Medical SciencesShanghai 200031China Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care Shanghai 200031China Shanghai Research Center of Ophthalmology and Optometry Shanghai 200031China

Dear Editor,We report a case with trans-photorefractive keratectomy(PRK)for recurrent epithelial corneal erosion caused by cooking oil after EVO-implantable contact lens(ICL)(EVO Visian ICL;STAAR Surgical AG,Switzerland),which should be distinguished from postoperative complications of *** corneal burns are classified as chemical and thermal burns,referring to direct contact injury to the cornea.

关键词： cooking erosion corneal

Prognostic significance and relationship of SMAD3 phosphoisoforms and VEGFR-1 in gastric cancer:A clinicopathological study

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World Journal of Gastrointestinal Oncology 2024年第1期16卷 118-132页

作者： Shi-Lin Lv pei Guo Jun-Rong Zou Ren-Sheng Chen ling-Yu Luo De-Qiang Huang Hospital of Gastroenterology Institute of Digestive DiseasesThe First Affiliated Hospital of Nanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Pathology Shenzhen Hospital of Southern Medical UniversityShenzhen 518000Guangdong ProvinceChina Institute of Urology The First Affiliated Hospital of Gannan Medical UniversityGanzhou 341000Jiangxi ProvinceChina Department of Pathology The First Affiliated Hospital of Nanchang UniversityNanchang 330006Jiangxi ProvinceChina

BACKGROUND The TGF-β/SMAD3 and VEGFR-1 signaling pathways play important roles in gastric cancer ***3 phosphorylation is a crucial prognostic marker in gastric *** To determine the prognostic value and relationship of SMAD3 phospho-isoforms and VEGFR-1 in gastric *** This was a single-center observational study which enrolled 98 gastric cancer patients and 82 adjacent normal gastric tissues from patients aged 32-84 years(median age 65)between July 2006 and April *** were followed up until death or the study ended(median follow-up duration of 28.5 mo).The samples were used to generate tissue microarrays(TMAs)for immunohistochemical(IHC)*** expressions of TGF-β1,pSMAD3C(S423/425),pSMAD3L(S204),and VEGFR-1 in gastric cancer(GC)tumor tissue and normal tissue were measured by IHC staining using TMAs obtained from 98 GC *** and survival information of the patients was recorded by Outdo Biotech from May 2007 to July *** relationship between TGF-β1,pSMAD3C(S423/425),pSMAD3L(S204),and VEGFR-1 protein expression levels was analyzed using Pearson's correlation *** relationship between protein expression levels and clinicopathological parameters was analyzed using the Chi-squared test.A survival curve was generated using the Kaplan-Meier survival *** TGFβ-1 and VEGFR-1 expression was significantly upregulated in gastric cancer tissue compared to adjacent noncancerous *** positive expression of phosphorylated isoforms of Smad3 varied depending on the phosphorylation site[pSMAD3C(S423/425):51.0%and pSMAD3L(S204):31.6%].High expression of pSMAD-3L(S204)was significantly correlated with larger tumors(P=0.038)and later N stages(P=0.035).Additionally,high expression of VEGFR-1 was closely correlated with tumor size(P=0.015)and pathological grading(P=0.013).High expression of both pSMAD3L(S204)and VEGFR-1 was associated with unfavorable outcomes in terms of overall survival(OS).Multiva

关键词： Gastric cancer pSMAD3L(S204) pSMAD3C(S423/425) Survival Transforming growth factor-β1 VEGFR-1

Analysis of sensitivity to hydrate blockage risk in natural gas gathering pipeline

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Petroleum Science 2024年第4期21卷 2723-2733页

作者： Ao-yang Zhang Meng Cai Na Wei Hai-Tao Li Chao Zhang Jun pei Xin-Wei Wang State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum University Research Institute of Production Engineering Daqing Oilfield Co.Ltd.

During the operational process of natural gas gathering and transmission pipelines, the formation of hydrates is highly probable, leading to uncontrolled movement and aggregation of hydrates. The continuous migration and accumulation of hydrates further contribute to the obstruction of natural gas pipelines, resulting in production reduction, shutdowns, and pressure build-ups. Consequently, a cascade of risks is prone to occur. To address this issue, this study focuses on the operational process of natural gas gathering and transmission pipelines, where a comprehensive framework is established. This framework includes theoretical models for pipeline temperature distribution, pipeline pressure distribution, multiphase flow within the pipeline, hydrate blockage, and numerical solution methods. By analyzing the influence of inlet temperature, inlet pressure, and terminal pressure on hydrate formation within the pipeline, the sensitivity patterns of hydrate blockage risks are derived. The research indicates that reducing inlet pressure and terminal pressure could lead to a decreased maximum hydrate formation rate, potentially mitigating pipeline blockage during natural gas transportation. Furthermore, an increase in inlet temperature and terminal pressure, and a decrease in inlet pressure, results in a displacement of the most probable location for hydrate blockage towards the terminal station. However,it is crucial to note that operating under low-pressure conditions significantly elevates energy consumption within the gathering system, contradicting the operational goal of energy efficiency and reduction of energy consumption. Consequently, for high-pressure gathering pipelines, measures such as raising the inlet temperature or employing inhibitors, electrical heat tracing, and thermal insulation should be adopted to prevent hydrate formation during natural gas transportation. Moreover, considering abnormal conditions such as gas well production and pipeline network s

关键词： Natural gas hydrates Gathering pipeline Temperature variation Hydrate formation rate Sensitivity analysis

Ascertaining the influences of auxiliary qubits on the Einstein–Podolsky–Rosen steering and its directions

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Chinese Physics B 2024年第5期33卷 213-221页

作者：邢玲玲杨欢张刚孔敏 School of Electrical and Photoelectronic Engineering West Anhui UniversityLu'an 237012China

Einstein–Podolsky–Rosen(EPR) steering is an example of nontrivial quantum nonlocality and characteristic in the non-classical *** directivity(or asymmetry) is a fascinating trait of EPR steering,and it is different from other quantum ***,we consider the strategy in which two atoms compose a two-qubit X state,and the two atoms are owned by Alice and Bob,*** atom of Alice suffers from a reservoir,and the atom of Bob couples with a bit flip *** influences of auxiliary qubits on EPR steering and its directions are revealed by means of the entropy uncertainty *** results indicate that EPR steering declines with growing time t when adding fewer auxiliary *** EPR steering behaves as damped oscillation when introducing more auxiliary qubits in the strong coupling *** the weak coupling regime,the EPR steering monotonously decreases as t increases when coupling auxiliary *** increases in auxiliary qubits are responsible for the fact that the steerability from Alice to Bob(or from Bob to Alice) can be more effectively ***,the introductions of more auxiliary qubits can change the situation that steerability from Alice to Bob is certain to a situation in which steerability from Bob to Alice is certain.

关键词： auxiliary qubits EPR steering directions influence

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Breast cancer and rectal cancer associated with Lynch syndrome:A case report

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World Journal of Clinical Oncology 2024年第9期15卷 1215-1221页

作者： pei-Fang Qin ling yang Jun-Ping Hu Jing-Yue Zhang Department of Laboratory Medicine The People Hospital of GuigangGuigang 537100Guangxi Zhuang Autonomous RegionChina

BACKGROUND The development mechanisms of Lynch syndrome(LS)-related breast cancer(BC)and rectal cancer are complex and variable,leading to personalized variations in diagnosis and treatment *** SUMMARY This paper presents a comprehensive review of clinical diagnosis and treatment data from a patient with LS-associated BC and rectal ***,screening data and management guidelines,as well as relevant literature on LS,are included in this *** study summarizes the molecular pathogenesis,clinicopathological features,and screening and management protocols for LS-associated BC and rectal *** Implementing early screening,prevention,and timely diagnosis and treatment measures is expected to reduce mitigate the incidence and mortality of LS-related BC and rectal cancer.

关键词： Lynch syndrome Breast cancer Rectal cancer Mismatch repair gene Case reports