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松材线虫检疫样品前处理机的研制

植物检疫 2017年第3期31卷 36-38页

作者：赵亚津王有福刘卉秋胡强屈菲杨宇崔博彩辽宁出入境检验检疫局辽宁大连116001

本文简要介绍了自行研制的松材线虫检疫样品前处理机的构造及其应用。该设备可以将日常检疫松材线虫的样品切割成符合检疫要求的木条,大大提高了松材线虫的检疫效率。适合在各口岸一线检疫部门广泛应用。

关键词：松材线虫样品前处理机

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断层识别技术及其在肇州油田的应用

石油物探 2011年第5期50卷 521-525,7页

作者：王鹏钟建华张亚金赵文栋王旭中国科学院广州地球化学研究所广东广州510640 中国石油天然气集团公司东方地球物理勘探有限责任公司研究院地质研究中心河北涿州072751 中国石油大学(华东) 山东青岛266555 中国石油天然气集团公司大庆油田勘探开发研究院黑龙江大庆163000 中国石油天然气集团公司渤海钻探工程有限公司天津300475

肇州油田州371区块位于肇州鼻状构造东翼,是油气运移的指向区。由于断层切割而发育有小断块和小断鼻,小断层对构造形态及油水关系影响大。针对该区块断层多、断距小、延伸短、多期发育、切割关系和组合关系复杂、小断层解释和识别难的... 详细信息

肇州油田州371区块位于肇州鼻状构造东翼,是油气运移的指向区。由于断层切割而发育有小断块和小断鼻,小断层对构造形态及油水关系影响大。针对该区块断层多、断距小、延伸短、多期发育、切割关系和组合关系复杂、小断层解释和识别难的地质特点,综合应用了相干体分析技术、沿层倾角方位角分析技术、频谱分解技术以及三维可视化技术等多种物探技术手段,结合地震剖面等多种信息,识别出常规地震数据体难以识别的小断层,并厘清了该区块断层的分布规律及接触关系,发现和落实了一批与小断层有关的低幅度构造,表现了精细构造解释的目的。

关键词：断层优势频带相干体倾角方位角频谱分解构造精细解释

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多特征融合驱动的聚类分阶段剩余寿命预测

机械设计与制造工程 2024年第4期53卷 94-98页

作者：赵文燕赵舜李雅婧中北大学机械工程学院山西太原030051

滚动轴承的剩余寿命预测对于机械设备的运行有着重要的意义,而过多的特征导致滚动轴承剩余寿命的预测精度降低。提出了一种多特征融合驱动的聚类分阶段剩余寿命预测方法,首先针对过多的冗余特征构建了基于评估指标的健康指标,用于描述... 详细信息

滚动轴承的剩余寿命预测对于机械设备的运行有着重要的意义,而过多的特征导致滚动轴承剩余寿命的预测精度降低。提出了一种多特征融合驱动的聚类分阶段剩余寿命预测方法,首先针对过多的冗余特征构建了基于评估指标的健康指标,用于描述轴承的退化过程;其次针对单一的退化轨迹无法精准地表征轴承健康状态的问题,提出了一种聚类阶段划分的方法,进行了轴承不同阶段的划分;然后提出了一种分阶段剩余寿命预测模型,在线识别当前阶段并准确预测轴承的剩余寿命;最后采用西安交通大学轴承数据集进行轴承剩余寿命预测,验证了所提方法的有效性与优越性。

关键词：滚动轴承多特征融合阶段划分在线状态识别剩余寿命

维普期刊数据库博看期刊

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盘锦口岸外来有害生物初步调查与分析

生物灾害科学 2021年第2期44卷 176-182页

作者：赵亚津王有福孙晓飞胡强刘卉秋洪滨大连海关辽宁大连116000

【目的】为了解盘锦口岸外来有害生物现状,掌握盘锦口岸外来有害生物数据,为盘锦口岸开发、建设和管理提供参考依据。【方法】主要采取线路调查的方式,结合文献资料和分子生物学手段,对盘锦口岸外来有害生物种类、生活型和生境、原产地... 详细信息

【目的】为了解盘锦口岸外来有害生物现状,掌握盘锦口岸外来有害生物数据,为盘锦口岸开发、建设和管理提供参考依据。【方法】主要采取线路调查的方式,结合文献资料和分子生物学手段,对盘锦口岸外来有害生物种类、生活型和生境、原产地、入侵方式等进行研究。【结果】初步确定盘锦口岸杂草和昆虫种一共137种,其中杂草84种25科,外来种39种,检疫性杂草3种;昆虫56种30科,均为中国种。(1)菊科杂草种类最多,有29种,占总数的35.8%。(2)杂草以1年生和2年生为主。(3)原产于美洲的杂草最多,有24种,占总数的61.5%;其次是欧洲,有12种,约占30.8%。(4)杂草长势不佳,因此并没有发生入侵状况,发现后铲除即可。【意义】盘锦口岸新开放粮食泊位,建议各部门严格把关、加强监管监测,科学引种,加强公众教育,提高公众意识,完善外来有害生物防治体系。

关键词：杂草昆虫调查分析

New record of Japanese snake blenny Xiphasia matsubarai(Perciformes：Blenniidae) from South China Sea

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Journal of Oceanology and Limnology 2018年第4期36卷 1401-1407页

作者： YI Murong zhao Chunxu SU Xin TAO yajin YAN Yunrong College of Fisheries Guangdong Ocean University Zhanjiang 524088 China Center of South China Sea Fisheries Resources Monitoring and Assessment Guangdong Ocean University Zhanjiang 524088 China Guangdong Provincial Engineering and Technology Research Center of Far Sea Fisheries Management and Fishing of South China Sea Zhanjiang 524088 China

Specimens belonging to the family Blenniidae were collected in a fishery resource investigation from the coastal waters of Xisha Islands and Hainan Island, South China Sea in 2016. Combining morphological results with sequence analysis, we identified one specimen as Xiphasia matsubarai Okada & Suzuki, 1952. This represents a new record in the South China Sea. In morphology, the specimen has the following traits: body elongated, eel-like or ribbon-like in shape; flanks medium flat; the head small bluntly rounded anteriorly and without a moustache; eyes is slightly smaller, on upper lateral position of head, which is about equal to 1/5 of the length of the head; body without scales, lateral line has been degraded; both sides of the upper and lower jaws with a canine; gill is opening at the top of the pectoral fin base, approximately equal to the length of eye diameter. Dorsal fin Ⅺ, 96; pectoral fin 10; anal fin Ⅱ, 95. Head and body grey-brown, including 26 dark grey-brown bands; abdomen and lower operculum yellowish grey and colour lighter; and dorsal base long with dark grey. Origin of dorsal is located over the anterior margin of pupil; black blotch on dorsal fin between 8 th and 10 th dorsal spine; anal and caudal fins dark grey, pectoral and ventral fins pale yellow. Sequence analysis of cytochrome oxidase subunit I gene( COI) strongly supports the identity of the specimen as Ⅹ. matsubarai.

关键词： new record Xiphasia matsubarai Blenniidae South China Sea DNA barcoding

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大叶杨组培快繁体系的建立

湖北林业科技 2015年第2期44卷 13-16页

作者：彭言劼李明勇赵亚津庞旭凤宋春草熊瑞婷杜克兵华中农业大学园艺林学学院武汉430070 湖北省林业调查规划院武汉430079

以大叶杨幼嫩的带腋芽茎段为试材,建立以腋芽诱导途径为基础的植株组培快繁体系。结果表明:大叶杨腋芽诱导的最适宜培养基为MS+NAA0.1 mg/L+6-BA0.1 mg/L,接种30 d,腋芽萌发率可达100%;最适宜增殖培养基为MS+NAA0.1 mg/L+6-BA2.0 mg/L,... 详细信息

以大叶杨幼嫩的带腋芽茎段为试材,建立以腋芽诱导途径为基础的植株组培快繁体系。结果表明:大叶杨腋芽诱导的最适宜培养基为MS+NAA0.1 mg/L+6-BA0.1 mg/L,接种30 d,腋芽萌发率可达100%;最适宜增殖培养基为MS+NAA0.1 mg/L+6-BA2.0 mg/L,培养30 d,增殖系数可达4.0,幼苗生长健壮;最佳生根培养基为1/2MS+NAA0.1mg/L+IBA0.2 mg/L,培养30 d,平均生根达4条,平均根长为4.7 cm。

关键词：大叶杨组织培养腋芽诱导快繁体系

Petroleum geological conditions and exploration potential of Lower Paleozoic carbonate rocks in Gucheng Area, Tarim Basin, China

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Petroleum Exploration and Development 2019年第6期46卷 1165-1181页

作者： CAO Yinghui WANG Shan ZHANG yajin YANG Min YAN Lei zhao Yimin ZHANG Junlong WANG Xiandong ZHOU Xiaoxiao WANG Hongjiang PetroChina Research Institute of Petroleum Exploration&Development Beijing 100083China Research Institute of Petroleum Exploration&Development PetroChina Daqing Oilfield CompanyDaqing 163712China China University of Petroleum Beijing 102249China Sinopec Management Institute Beijing 100012China

Lower Paleozoic carbonate rocks are an important exploration area in craton area of the Tarim Basin,with the proven oil and gas reserves of more than 2.2×10^8 t,but no large-scale discovery has been made in the Gucheng area so *** key issues restricting exploration are that the source rock,reservoir scale and law of oil and gas enrichment are *** systematically examining the petroleum geological conditions of Lower Paleozoic carbonate rocks,the following findings are reached:(1)Source rocks of slope-basin facies developed in Cambrian-Lower Ordovician in the Gucheng area.(2)The dolomitized beach in the lower part of Ordovician Yingshan Formation has large-scale reservoirs,good reservoir-cap assemblage and developed gas source faults,and is an important field for increasing reserves and production in the near future;hydrocarbon enrichment is controlled by reservoir and gas source faults,and the central dolomitized beach zone is the main exploration area.(3)The Cambrian platform margin reef beach,large in scale,good in physical properties and close to source rocks,has the possibility to form monolithic gas field;the caprock and preservation conditions are the key factors for hydrocarbon enrichment;the northern part of the phasesⅠandⅡplatform margin reefs has better sealing conditions,and is the main direction of next exploration.(4)Limestone fault solution reservoirs in the upper part of Ordovician Yingshan Formation,controlled by faults and small in scale,but good in reservoir-cap combination,worth exploring.(5)The granular limestone beach of Ordovician Yijianfang Formation is well developed and gas-bearing,but short in exposure dissolution time,and the reservoirs are strongly heterogeneous,and are a potential exploration field.

关键词： Tarim Basin Gucheng Area Lower Paleozoic carbonate rock petroleum geological conditions exploration potential

基于国家药品集中带量采购政策的北京市抗肿瘤靶向药物的可负担性评价

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临床药物治疗杂志 2024年第7期22卷 23-28页

作者：韩亚进赵紫楠李可欣张天齐朱柏霖纪立伟金鹏飞胡欣罗小峰赵飞兰州大学公共卫生学院兰州730000 北京医院药学部北京100730 北京医院临床试验研究中心、国家老年医学中心、中国医学科学院老年医学研究院、药物临床风险与个体化应用评价北京市重点实验室北京100730

目的了解国家药品集中带量采购(以下简称集采)政策实施前后,北京市抗肿瘤靶向药物的可负担性变化。方法基于前9批集采中选抗肿瘤靶向药物的价格信息,采用改进后的WHO和国际健康行动机构标准调查法,分别以最低日工资标准和年人均可支配... 详细信息

目的了解国家药品集中带量采购(以下简称集采)政策实施前后,北京市抗肿瘤靶向药物的可负担性变化。方法基于前9批集采中选抗肿瘤靶向药物的价格信息,采用改进后的WHO和国际健康行动机构标准调查法,分别以最低日工资标准和年人均可支配收入为指标评价集采政策对抗肿瘤靶向药物的影响。结果集采政策实施后,12个品规的药品价格均降低,降幅为25.05%~97.71%,月药品费用支出由集采前最低日工资的10.33~1030.96倍降低至集采后的2.70~189.36倍。城镇未参保患者、城镇职工医保患者和城镇城乡居民医保患者支付年度治疗费用所需工作年数分别从集采前的0.12~11.28年、0.03~6.08年和0.04~8.90年下降至集采后的0.03~2.23年、0.02~0.35年和0.02~0.51年,农村未参保患者和农村城乡居民医保患者支付年度治疗费用所需工作年数分别从集采前的0.31~27.62年和0.10~21.79年下降至集采后的0.07~5.61年和0.04~1.27年。结论集采政策实施后,北京市居民抗肿瘤靶向药物的可负担性明显改善,但仍有部分基础价格居高的药品对患者有一定的经济压力。

关键词：国家药品集中带量采购抗肿瘤靶向药物可负担性

Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer’s disease

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Animal Models and Experimental Medicine 2021年第3期4卷 233-242页

作者： Zhiqi Song yajin Qu Yanfeng Xu Ling Zhang Li Zhou Yunlin Han Wenjie zhao Pin Yu Yu Zhang Xianglei Li Chuan Qin Key Laboratory of Human Disease Comparative Medicine Chinese Ministry of HealthBeijing Key Laboratory for Animal Models of Emerging and Remerging Infectious DiseasesInstitute of Laboratory Animal ScienceChinese Academy of Medical Sciences and Comparative Medicine CenterPeking Union Medical CollegeBeijingChina

Background:Alzheimer's disease(AD)is an incurable and irreversible neurodegen-erative disease,without a clear ***,identification of candidates before amyloid-βplaque(Aβ)deposition proceeds is of major significance for earlier intervention in ***:To explore the potential noninvasive earlier biomarkers of AD in a 5XFAD mouse model,microRNAs(miRNAs)from urinary exosomes in 1-month-old pre-Aβaccumulation 5XFAD mice models and their littermate controls were profiled by mi-croarray *** differentially expressed miRNAs were further analyzed via droplet digital PCR(ddPCR).Results:Microarray analysis demonstrated that 48 differentially expressed miRNAs(18 upregulated and 30 downregulated),of which six miRNAs-miR-196b-5p,miR-339-3p,miR-34a-5p,miR-376b-3p,miR-677-5p,and miR-721-were predicted to display gene targets and important signaling pathways closely associated with AD pathogenesis and verified by ***:Urinary exosomal miRNAs showing differences in expression prior to Aβ-plaque deposition were *** exosomal miRNAs represent potential noninvasive biomarkers that may be used to prevent AD in clinical applications.

关键词： 5XFAD mouse model Alzheimer's disease biomarkers microarray miRNA urinary exosome