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A Tiny RNA Molecule with a Big Impact on Type 2 Diabetes Mellitus Susceptibility

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Biomedical and Environmental Sciences 2017年第11期30卷 855-861页

作者： ZHUANG Guo Qing WANG you xin College of Animal Science and Veterinary Medicine Henan Agricultural University Beijing Key Laboratory of Clinical Epidemiology School of Public Health Capital Medical University

Biological molecules could be used as risk assessment tools for predicting incident Type 2Diabetes Mellitas（T2DM）,such as microR NAs（mi RNAs）.Numerous studies have shown association between miR NA and susceptibility of T2DM,suggesting that mi RNAs might be common biological factors for ***,miR NAs could also serve as novel biomarkers for T2DM epidemiology

关键词： A Tiny RNA Molecule a Big Impact on Type 2 Diabetes Mellitus Susceptibility

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聚焦生态文明建设提升新疆新质生产力水平

新疆师范大学学报（自然科学版） 2025年第1期44卷 72-82页

作者：牛军政张新友喀什大学马克思主义学院新疆喀什844000 中共新疆维吾尔自治区委员会党校决策咨询部新疆乌鲁木齐830002

高质量发展作为新疆深入实施中国式现代化实践的首要要务,是驱动新疆改革发展稳定事业迈向新阶段的关键引擎。聚焦高质量发展任务,扎实推进这一进程,不仅要牢固树立高质量发展理念,更需加速推进现代化实践步伐,其意义深远而重大。本研... 详细信息

高质量发展作为新疆深入实施中国式现代化实践的首要要务,是驱动新疆改革发展稳定事业迈向新阶段的关键引擎。聚焦高质量发展任务,扎实推进这一进程,不仅要牢固树立高质量发展理念,更需加速推进现代化实践步伐,其意义深远而重大。本研究揭示,新疆在大气环境治理方面需进一步加大力度;水污染防治虽已取得显著成效,但仍需不懈努力;土壤资源治理尚处于较低水平,土地荒漠化问题严峻。同时,污染防治基础设施与能源消耗管理需更紧密融合。展望未来,新疆在追求高质量发展的道路上,应依托科技创新引领现代化产业体系的构建,为高质量发展奠定坚实的产业基础;坚持结构优化导向,推动发展模式的深刻变革;将环境保护作为核心驱动力,紧扣高质量发展首要任务;加速绿色生产方式转型,提升投资贸易的质效水平;不断优化制度设计,以高质量发展新成效扎实推进中国式现代化新疆实践。

关键词：高质量发展绿色发展新质生产力新疆

Collective radiance of giant atoms in non-Markovian regime

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Science China(Physics,Mechanics & Astronomy) 2023年第2期66卷 79-86页

作者： Qing-Yang Qiu Ying Wu xin-you Lü School of Physics Huazhong University of Science and TechnologyWuhan 430074China

We investigate the non-Markovian dynamics of two giant artificial atoms interacting with a continuum of bosonic modes in a onedimensional(1D) *** on the diagrammatic method,we present the exact analytical solutions,which predict the rich phenomena of collective *** the certain collective states,the decay rates are found to be far beyond that predicted in the the Dicke model and standard Markovian framework,which indicates the occurrence of *** superadiance-to-subradiance transition could be realized by adjusting the exchange symmetry of giant ***,there exist multiple bound states in continuum(BICs),with photons/phonons bouncing back and forth in the cavity-like geometries formed by the coupling *** trapped photons/phonons in the BICs can also be re-released conveniently by changing the energy level splitting of giant *** mechanism relies on the joint effects of the coherent time-delayed feedback and the interference between the coupling points of giant *** work fundamentally broadens the fields of giant atom collective radiance by introducing *** also paves the way for a clean analytical description of the nonlinear open quantum system with more complex retardation.

关键词： collective symmetry conveniently

A P2P streaming service architecture with distributed caching

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第4期8卷 605-614页

作者： GUO Pan-hong YANG Yang LI xin-you Department of Computer Science and Technology University of Science and Technology Beijing Beijing 100083 China China State Information Center Beijing 100045 China

Multimedia streaming served through peer-to-peer (P2P) networks is booming nowadays. However, the end-to-end streaming quality is generally unstable due to the variability of the state of serve-peers. On the other hand, proxy caching is a bandwidth-efficient scheme for streaming over the Internet, whereas it is a substantially expensive method needing dedicated powerful proxy servers. In this paper, we present a P2P cooperative streaming architecture combined with the advantages of both P2P networks and multimedia proxy caching techniques to improve the streaming quality of participating clients. In this frame- work, a client will simultaneously retrieve contents from the server and other peers that have viewed and cached the same title before. In the meantime, the client will also selectively cache the aggregated video content so as to serve still future clients. The associate protocol to facilitate the multi-path streaming and a distributed utility-based partial caching scheme are detailedly dis- cussed. We demonstrate the effectiveness of this proposed architecture through extensive simulation experiments on large, Inter- net-like topologies.

关键词： Cooperative steaming Peer-to-peer networks Partial caching scheme Distributed caching

Dynamical behavior of a delayed prey-predator-scavenger system with fear effect and linear harvesting

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International Journal of Biomathematics 2021年第4期14卷 159-188页

作者： xin-you Meng Jie Li School of Science Lanzhou University of Technology LanzhouGansu 730050P.R.China College of Technology and Engineering Lanzhou University of Technology Lanzhou Gansu 730050P.R.China

In this paper,we propose a delayed prey-predator-scavenger system with fear effect and linear ***,we discuss the existence and stability of all possible ***,we investigate the existence of Hopf bifurcation of the delayed system by regarding the gestation period of the scavenger as a bifurcation ***,we obtain the direction of Hopf bifurcation and the stability of bifurcating periodic solutions by using the normal form theory and the central manifold *** addition,we give the optimal harvesting strategy of the delayed system based on Pontryagin's maximum principle with ***,some numerical simulations are carried out to verify our theoretical results.

关键词： Prey-predator-scavenger fear effect time delay Hopf bifurcation optimal harvesting policy

Synthesis of highly active Cu(Ⅰ)-Y(Ⅲ)-Y zeolite and its selective adsorption desulfurization performance in presence of xylene isomers

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Petroleum Science 2021年第1期18卷 295-306页

作者： Bo-Long Jiang Nan Jiang you-xin Chang Innovation Institute for Sustainable Maritime Architecture Research and Technology Qingdao University of TechnologyQingdao 266000China Chongqing Changshou Sino French Water Co.Ltd. Chongqing 404100China

A bimetal-exchanged NaY zeolite(Cu(Ⅰ)-Y(Ⅲ)-Y)with a desirable adsorptive desulfurization(ADS)performance was prepared and characterized by means of X-ray diffraction,specific surface area measurements,X-ray fluorescence spectrometer,X-ray photoelectron spectroscopy,thermal gravity analysis and Fourier transform infrared *** effect of Y(Ⅲ)ions on ADS in the presence of the xylenes was *** indicated that the ADS performance of Y(Ⅲ)-Y is higher than that of most reported *** Y(Ⅲ)-based Cu(Ⅰ)-Y(Ⅲ)-Y demonstrated the higher breakthrough loading than those of reported Ce(Ⅲ)/Ce(Ⅳ)-based transition metal Y zeolites,showing that Y(Ⅲ)ions play a promoting role in improving the ADS *** Cu(Ⅰ)-Y(Ⅲ)-Y,a new strong S-M interaction(S stands for sulfur,while M stands for metal)active site was formed,which might be caused by the synergistic effect between Cu(Ⅰ)and Y(Ⅲ).The Cu(Ⅰ)-Y(Ⅲ)-Y,which combined the advantages of Cu(I)-Y and Y(Ⅲ)-Y,is a kind of promising *** breakthrough loading decreased in the order of Cu(Ⅰ)-Y(Ⅲ)-Y>Y(Ⅲ)-Y>Cu(Ⅰ)-Y,and the effect of xylene isomers on the sulfur removal was in the order of ortho-xylene>meta-xylene>para-xylene,which exhibited the same trend with the bond order of xylenes.

关键词： Desulfurization Yttrium Copper Y zeolite Competitive adsorption Xylenes

A Bird’s Eye View of Quantitative Proteome of Tumor Tissues from Lung Cancer Patients by a High Precision Mass Spectrometry Method

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Chemical Research in Chinese Universities 2024年第1期40卷 136-144页

作者： DU Xiaohui LI Encheng WANG Qi you xin Lung Cancer Transitional Medicine Center The Second Affiliated Hospital of Dalian Medical UniversityDalian116023P.R.China Department of Scientific Research Center The Second Affiliated Hospital of Dalian Medical UniversityDalian116023P.R.China Department of Respiratory Medicine The Second Affiliated Hospital of Dalian Medical UniversityDalian116023P.R.China

Lung cancer produces a high incidence of malignant *** have been many studies on lung cancer using mass spectrometry(MS)***,most studies have focused on humoral *** this work,26 pairs of tissue samples(tumor ***-tumor)from patients with lung cancer were analyzed using liquid chromatography-tandem MS(LC-MS/MS)with data-independent acquisition *** total,3152 proteins were quantified from tissue samples with high confidence,including 189 up-regulated and 522 down-regulated proteins(tumor ***-tumor).In addition,79 and 690 proteins were identified only in para-cancerous samples and cancerous samples,*** results from bio-informatics tools indicated that altered proteins like PEBP1,HRG and LYZ could be ideal reservoirs for screening the potential biomarkers for lung *** is believed these tissue-specific proteomics results will assist in the studies of lung cancer.

关键词： Lung cancer Proteome Data-independent aquisition

Lipid accumulation and protein modifications of Bruch’s membrane in age-related macular degeneration

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International Journal of Ophthalmology(English edition) 2021年第5期14卷 766-773页

作者： Li-Hui Meng you-xin Chen Department of Ophthalmology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Key Laboratory of Ocular Fundus Diseases Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China

Age-related macular degeneration(AMD)is a progressive retinal disease,which is the leading cause of blindness in western *** is an urgency to establish new therapeutic strategies that could prevent or delay the progression of AMD more *** now,the pathogenesis of AMD has remained unclear,limiting the development of the novel ***’s membrane(BM)goes through remarkable changes in AMD,playing a significant role during the disease *** main aim of this review is to present the crucial processes that occur at the level of BM,with special consideration of the lipid accumulation and protein ***,some therapies targeted at these molecules and the construction of BM in tissue engineering of retinal pigment epithelium(RPE)cells transplantation were ***,this review may provide a reference for researchers engaged in pathogenesis or management on AMD.

关键词： Bruch’s membrane lipid accumulation protein modifications therapy

Analysis of a delayed diffusive model with Beddington-DeAngelis functional response

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International Journal of Biomathematics 2019年第4期12卷 277-300页

作者： xin-you Meng Jiao-Guo Wang School of Science Lanzhou University of Technology Lanzhou Gansu 730050 P. R.China

In this paper, a delayed diffusive phytoplankton-zooplankton model with Beddington DeAngelis functional response and toxins is investigated. Existence of equilibria of the system are solved. The global asymptotic stability of the zooplankton-free equilibrium is obtained. The local stability of the coexistent equilibrium and existence of Hopf bifurcation are discussed. In addition, the properties of the Hopf bifurcation are studied based on the center manifold and normal form theory for partial differential equations. Finally, some numerical simulations are also carried out to confirm our theoretical analysis.

关键词： Phytoplankton-zooplankton time delay stability Hopf bifurcation diffusive Beddington-DeAngelis