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The World of Chinese 2013年第6期 60-61页

作者： A.z.

There is a legendary,though perhaps apocryphal,story regarding Xu Bing’s most famous and influential artwork'Book from the Sky'(天书tionshu)—Xu’s bold creation of 4,000'false'Chinese characters.A senior editor at a

关键词： very Book COUNTeRFeIT ChARACTeRS

pancreatic cancer diagnosis by free and exosomal miRNA

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World Journal of Gastrointestinal pathophysiology 2013年第4期4卷 74-90页

作者： Margot zller department of Tumor Cell Biology University Hospital of Surgery

patients with pancreatic adenocarcinoma(paCa) have a dismal prognosis. This is in part due to late diagnosis prohibiting surgical intervention, which provides the only curative option as paCa are mostly chemo- and radiation resistance. hope is raised on a reliable noninvasive/minimally invasive diagnosis that is still missing. Recently two diagnostic options are discussed, serum MicroRNA(miRNA) and serum exosomes. Serum miRNA can be free or vesicle-, particularly, exosomesenclosed. This review will provide an overview on the current state of the diagnostic trials on free serum miRNA and proceed with an introduction of exosomes that use as a diagnostic tool in serum and other body fluids has not received sufficient attention, although serum exosome miRNA in combination with protein marker expression likely will increase the diagnostic and prognostic power. By their crosstalk with host cells, which includes binding-initiated signal transduction, as well as reprogramming target cells via the transfer of proteins, mRNA and miRNA exosomes are suggested to become a most powerful therapeutics. I will discuss which hurdles have still to be taken as well as the different modalities, which can be envisaged to make therapeutic use of exosomes. paCa are known to most intensely crosstalk with the host as apparent by desmoplasia and frequent paraneoplastic syndromes. Thus, there is hope that the therapeutic application of exosomes brings about a major breakthrough.

关键词： pancreatic cancer exosomes MicroRNA diagnosis Serum

中国五批3610个国家级非物质文化遗产空间分布数据集

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全球变化数据学报（中英文） 2022年第2期6卷 257-264,429-436页

作者：郭宇姚亦锋鄢继尧王振波李嘉欣南京师范大学地理科学学院南京210023 中国科学院地理科学与资源研究所北京100101 中央民族大学民族学与社会学学院北京100081

非物质文化遗产是中华民族智慧与文明的结晶,加强非物质文化遗产的研究与保护对提升丰富世界文化和发扬中华传统具有重要意义。基于国务院2006、2008、2011、2014和2021年先后五次发布的3610个国家级非物质文化遗产代表性项目名录,根据... 详细信息

非物质文化遗产是中华民族智慧与文明的结晶,加强非物质文化遗产的研究与保护对提升丰富世界文化和发扬中华传统具有重要意义。基于国务院2006、2008、2011、2014和2021年先后五次发布的3610个国家级非物质文化遗产代表性项目名录,根据非物质文化遗产地或单位地理位置将各非遗项目进行空间化表达进而获得中国五批国家级非物质文化遗产空间分布数据集。该数据集包括了每个非遗项目的编号、名称、类别、公布时间、类型、申报地区或单位、保护单位及省份等信息。数据集以.shp格式存储,由8个数据文件组成,数据量为15.1 MB(压缩为1个文件,292 KB)。

关键词：非物质文化遗产(非遗) 空间分布国家级中国

A Framework for Active Learning of Beam Alignment in Vehicular Millimeter Wave Communications by Onboard Sensors

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zTe Communications 2019年第2期17卷 2-9,58页

作者： erich z?chmann Christian doppler Laboratory for dependable Wireless Connectivity for the Society in Motion Institute of Telecommunications

estimating time-selective millimeter wave wireless channels and then deriving the optimum beam alignment for directional antennas is a challenging *** solve this problem,one can focus on tracking the strongest multipath components(MpCs).Aligning antenna beams with the tracked MpCs increases the channel coherence time by several orders of *** contribution suggests tracking the MpCs *** derived geometric tracker is based on algorithms known as doppler bearing tracking.A recent work on geometric-polar tracking is reformulated into an efficient recursive *** the relative position of the MpCs is known,all other sensors on board a vehicle,e.g.,lidar,radar,and camera,will perform active learning based on their own observed *** learning the relationship between sensor data and MpCs,onboard sensors can participate in channel *** tracking of many integrated sensors will increase the reliability of MpC tracking.

关键词： adaptive filters autonomous vehicles directive antennas doppler measurement intelligent vehicles machine learning millimeter wave communication

Recent progress in matter in extreme states created by laser

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Matter and Radiation at extremes 2022年第1期7卷 1-4页

作者： K.Batani d.Batani X.T.he K.Shigemori Institute of plasma physics and Laser Micro Fusion WarsawPoland University of Bordeaux CEACNRSUMR 510733405 TalenceFrance plasma physics department National Research Nuclear University MEPhIMoscowRussia Center for Applied physics and Technology Peking UniversityBeijingChina Institute of Applied physics and Computational Mathematics BeijingChina Institute of Laser engineering Osaka UniversityOsakaJapan

*** Strong interest in the modeling of planetary interiors,dwarf stars,and the physical conditions necessary to achieve inertial confinement fusion(ICF)have driven attention to the properties of matter at high density,temperature,and pressure(beyond the megabar limit).extreme states of matter have been studied using gas guns,explosives,and z-pinches,among other methods(see,e.g.,Refs.1–4).however in recent years,lasers have become the most reliable standard tool for creating extreme states of matter.

关键词： extreme laser states

Magnetic properties and magnetic phase diagrams of intermetallic compound GdMn2Ge2

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Chinese physics B 2003年第6期12卷 655-660页

作者：郭光华张海贝 R.z.Levitin SchoolofphysicsScienceandTechnology CentralSouthUniversityChangsha410083China departmentofphysics M.V.LomonsovMoscowStateuniversity119899Moscow.Russia

A modified yafet-Kittle model is applied to investigate the magnetic properties and magnetic phase transition of the intermetallic compound *** analysis and calculation show that there are five possible magnetic structures in *** of external magnetic field and temperature give rise to the first-order or secondorder magnetic transitions from one phase to *** on this model,the magnetic curves of GdMn2Ge2 single crystals at different temperatures are calculated and a good agreement with experimental data has *** on the calculation,the h-T magnetic phase diagrams of GdMn2Ge2 are *** Gd-Gd,Gd-Mn,intralayer Mn-Mn and interlayer Mn-Mn exchange coupling parameters are *** is shown that,in order to describe the magnetic properties of GdMn2Ge2,the lattice constant and temperature dependence of interlayer Mn-Mn exchange interaction must be taken into account.

关键词： rare earth intermetallics magnetic phase transition magnetic structure

Status Report of the NSCL/MSU eCR Ion Sources

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Chinese physics C 2007年第S1期31卷 18-22页

作者： p.A.závodszky B.Mend d.Cole J.deKamp M.doleans G.Machicoane F.Marti p.Miller J.Moskalik W.Nurnberger J.Ottarson M.Steiner J.Stetson J.Vincent A.zeller National Superconducting Cyclotron Laboratory Michigan State UniversityEast LansingMI 48824USA

Since the last eCR Workshop,NSCL/MSU has been involved in a vigorous eCR ion source R&d program,which resulted in the construction of an off-line test eCR ion source(ARTeMIS-B)for new beam development and ion optics *** the design and partial completion of a 3rd generation,fully supercon- ducting eCR ion source,SuSI has been *** paper is an overview of the construction projects and the different R&d activities performed with the existing ion *** activities include development of metallic ion beam production methods using evaporation with resistive and inductive ovens and sputtering of very refractory *** optics developments include testing different focusing elements(magnetic solenoid lens,electrostatic quadrupole triplet lens,einzel lens,electrostatic double doublet quadrupole combined with an octupole lens),and different beam forming and diagnostics *** detailed results will be presented at the workshop in separate talks and posters.

关键词： eCR ion sources highly charged ions beam optics

Synaptic metaplasticity through NMdA receptor lateral diffusion

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南京医科大学学报(自然科学版) 2008年第5期 645-645页

作者： zhao, J. peng, y. Xu, z. Chen, R. Q. Gu, Q. h. Chen, z. Lu, W. Nanjing Med Univ, dept Neurobiol, Key Lab Neurodegenerat dis Jiangsu prov, Nanjing 210029, Jiangsu prov, peoples R China. Nanjing Med Univ, Key Lab human Funct Gen Jiangsu prov, Nanjing 210029, Jiangsu prov, peoples R China

Lateral diffusion of glutamate receptors was proposed as a mechanism for regulating receptor numbers at synapses and affecting synaptic functions, especially the efficiency of synaptic transmission. however, a direct link between receptor lateral diffusion and change in synaptic function has not yet been established. In the present study, we demonstratedNMdAreceptor(NMdAR) lateral diffusion in CA1 neurons in hippocampal slices by detecting considerable recovery of spontaneous or evoked epSCs from the block of (+)-MK-801[(+)-5-methyl-10,11-dihydro-5h-dibenzo[a,d] cyclohepten-5,10-imine maleate], an irreversible NMdAR open-channel blocker. We observed changes on both the number and the composition of synaptic NMdAR on recovery. More importantly, after the recovery, long-term potentiation(LTp)-producing protocol induced only LTd(long-term depression) instead of LTp. In contrast, a complete recovery from competitive NMdAR blocker d,L-Ap-5 was observed without subsequent changes on synaptic plasticity. Our data suggest a revised model of NMdAR trafficking wherein extrasynaptic NMdARs, mostly NR1/NR2B receptors, move laterally into synaptic sites, resulting in altered rule of synaptic modification. Thus, CA1 synapses exhibit a novel form of metaplasticity in which the direction of synaptic modification can be reverted through subtype-specific lateral diffusion of NMdA receptors.

关键词： NMdA receptor lateral diffusion LTp LTd MK-801 Ap-5 long-term potentiation activity-dependent regulation cultured hippocampal-neurons mouse visual-cortex ampa receptor differential roles dendritic spines plasticity activation trafficking

梅尼埃病患者c VeMps与内淋巴积水相关性研究进展

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中国听力语言康复科学杂志 2024年第4期22卷 409-412页

作者：李璐王林娥首都医科大学附属北京友谊医院耳鼻咽喉头颈外科北京100050

梅尼埃病(Meniere’s disease,Md)是常见的耳源性眩晕疾病,主要表现为发作性眩晕,波动性听力下降,耳鸣和耳胀满感。目前病因不明,其主要的病理学特点为内淋巴的产生与吸收失衡导致的内淋巴积水,内耳核磁钆造影使得内淋巴积水可视化,前... 详细信息

梅尼埃病(Meniere’s disease,Md)是常见的耳源性眩晕疾病,主要表现为发作性眩晕,波动性听力下降,耳鸣和耳胀满感。目前病因不明,其主要的病理学特点为内淋巴的产生与吸收失衡导致的内淋巴积水,内耳核磁钆造影使得内淋巴积水可视化,前庭积水导致前庭功能下降,颈前庭诱发肌源性电位各参数异常,已有国内外相关文献报道两者对于梅尼埃病的应用价值。本文旨总结二者在梅尼埃病中的应用价值,分析相关性,以进一步总结归纳梅尼埃病形态变化与功能变化之间的联系,更好地应用于临床,指导梅尼埃病的诊断和治疗。

关键词：梅尼埃病颈前庭诱发肌源性电位内淋巴积水内耳核磁钆造影