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High-frequency microwave cavity design for high-mass dark matter axion searches

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Chinese Physics B 2024年第5期33卷 87-94页

作者：张驰王佳李春光陈石广程航孙亮吴云 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China Hefei National Laboratory Hefei 230088China

The haloscope based on the TM_(010)mode cavity is a well-established technique for detecting QCD ***,the method has limitations in detecting high-mass axion due to significant volume loss in the high-frequency *** a higher-order mode cavity can effectively reduce the volume loss of the high-frequency *** rotatable dielectric pieces as a tuning mechanism can compensate for the degradation of the form factor of the higher-order ***,the introduction of dielectric causes additional volume *** address these issues,this paper proposes a novel design scheme by adding a central metal rod to the higher-order mode cavity tuned by dielectrics,which improves the performance of the haloscope due to the increased effective volume of the cavity *** superiority of the novel design is demonstrated by comparing its simulated performance with previous ***,the feasibility of the scheme is verified by the full-wave simulation results of the mechanical design model.

关键词： axion haloscope microwave cavity

Impurity modes in two-dimensional strongly coupled complex plasma crystals

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Plasma Science and Technology 2024年第8期26卷 1-7页

作者：吴诗杰徐韵乔冼顺宇何向磊杨肖易 School of Energy Science and Engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China School of Physics Harbin Institute of TechnologyHarbin 150001People’s Republic of China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China

Complex plasma fluctuation processes have been extensively studied in many aspects,especially lattice waves in strongly coupled plasma crystals,which are of great significance for understanding fundamental physical phenomena.A challenge of experimental investigations in two-dimensional strongly coupled complex plasma crystals is to keep the main body and foreign particles of different masses on the same horizontal *** solve the problem,we have proposed a potential well formed by two negatively biased grids to bind the negatively charged particles in a two-dimensional(2D)plane,thus achieving a 2D plasma crystal in the microgravity *** study of such phenomena in complex plasma crystals under microgravity environment then becomes *** this paper,we focus on the continuum spectrum,including both phonon and optic branches of the impurity mode in a 2D system in microgravity *** results show the dispersion relation of the longitudinal and transverse impurity oscillation modes and their *** the macroscopic visibility of complex mesoscopic particle lattices,theoretical and experimental studies on this kind of complex plasma systems will help us further understand the physical nature of a wide range of condensed matters.

关键词： microgravity environment complex plasma lattice dispersion relation

Withered branch-like changes of intrahepatic bile ducts:a rare complication of acute severe biliary pancreatitis

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Hepatobiliary Surgery and Nutrition 2024年第5期13卷 913-916页

作者： kun He Xiaxiao yan Miaoyan Zhang Zhiwei Wang Dong wu Department of Gastroenterology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Eight-year Medical Doctor Program Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Internal Medicine Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Radiology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Secondary sclerosing cholangitis(SSC)is a chronic biliary disease characterized by inflammatory responses,fibrous occlusion,strictures,and progressive destruction of intrahepatic and/or extrahepatic bile ducts,which may lead to cholestasis and cirrhosis(1).Well-described causes of SSC include infectious,ischemic,toxic,immunologic,congenital disorders and so on(2,3).Here,we presented a rare case of sclerosing cholangitis secondary to acute severe biliary pancreatitis.

关键词： biliary acute pancreatitis

天津市PM_(2.5)碳组分空间差异性及来源解析

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环境科学 2024年第3期45卷 1328-1336页

作者：武甫亮吴建会戴启立肖致美冯银厂南开大学环境科学与工程学院国家环境保护城市空气颗粒物污染防治重点实验室天津300350 天津市生态环境监测中心天津300191

2021年在天津市不同功能区共设置4个点位同步采集细颗粒物(PM_(2.5))样品,测定了其中8种碳质亚组分的含量.结果表明,采样期间各点位ρ[有机碳(OC)]为3.7~4.4μg·m^(-3),ρ[元素碳(EC)]为1.6~1.7μg·m^(-3),OC浓度在中心城区最高,EC浓... 详细信息

2021年在天津市不同功能区共设置4个点位同步采集细颗粒物(PM_(2.5))样品,测定了其中8种碳质亚组分的含量.结果表明,采样期间各点位ρ[有机碳(OC)]为3.7~4.4μg·m^(-3),ρ[元素碳(EC)]为1.6~1.7μg·m^(-3),OC浓度在中心城区最高,EC浓度差别较小.采用最小比值法对二次有机碳(SOC)进行估算,结果表明环城区二次污染较为突出,SOC占OC的比例达48.8%.各功能区碳质亚组分间的相关性强弱呈现出外围区>中心城区>环城区的特征,均表现出EC1与OC2和EC1与OC4相关性最强.正定矩阵因子(PMF)来源解析结果显示,道路扬尘源(9.7%~23.5%)、燃煤源(10.2%~13.3%)、柴油车尾气(12.6%~20.2%)和汽油车尾气(18.9%~38.8%)是天津市PM_(2.5)中碳组分的主要来源.不同功能区碳组分污染源存在差异,中心城区和外围区主要受汽油车尾气影响;环城区受二次污染和柴油车尾气的影响更为突出.

关键词：天津 PM_(2.5) 碳组分空间差异来源解析

Novel machine learning paradigms-enabled methods for smart building operations in data-challenging contexts:Progress and perspectives

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National Science Open 2024年第3期3卷 88-109页

作者： Cheng Fan yutian Lei Jinhan Mo Huilong Wang Qiuting wu Jiena Cai key Laboratory for Resilient Infrastructures of Coastal Cities Ministry of EducationShenzhen University Sino-Australia Joint Research Center in BIM and Smart Construction Shenzhen University College of Civil and Transportation Engineering Shenzhen University

The increasing availability of building operational data has greatly encouraged the development of advanced data-driven technologies for smart building *** operational data typically suffer from data quality problems,such as insufficient labeled and imbalanced data,making them incompatible with conventional machine learning *** advances in data science have provided novel machine learning paradigms to tackle such data challenges for practical applications,such as transfer learning,semi-supervised learning,and generative *** review aims to present the progress and perspectives on the effective utilization of novel machine learning paradigms for three major building energy management tasks,i.e.,building energy predictions,fault detection and diagnosis,and control ***-depth discussions have been provided to demonstrate the pros and cons of different learning approaches in terms of data compatibility,modeling difficulties,and possible application scenarios,which could be helpful for enhancing the feasibility of data-driven technologies for smart building operations.

关键词： smart building operations building energy management transfer learning semi-supervised learning generative learning

晋南地区煤系黏土岩中锂的赋存状态及其沉积环境

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地质学报 2024年第8期98卷 2395-2408页

作者：程宏飞武振晓长安大学地球科学与资源学院陕西西安710054

关键金属锂等战略资源及其引发的国家安全问题,在当今国际政治、经济、军事舞台中愈显突出和重要。华北克拉通是我国沉积型锂矿床主要分布区域之一,富锂黏土岩资源丰富,成为重要的沉积型锂资源勘探区域。本文以华北克拉通晋南地区的煤... 详细信息

关键金属锂等战略资源及其引发的国家安全问题,在当今国际政治、经济、军事舞台中愈显突出和重要。华北克拉通是我国沉积型锂矿床主要分布区域之一,富锂黏土岩资源丰富,成为重要的沉积型锂资源勘探区域。本文以华北克拉通晋南地区的煤系黏土岩为研究对象,利用X射线粉末衍射(XRD)、X射线荧光光谱(XRF)、电感耦合等离子体质谱(ICP-MS)、傅里叶变换红外光谱(FTIR)和魔角旋转固体核磁共振谱(MAS NMR)等表征技术,结合化学物相分析及黏土矿物分离提取实验对研究区本溪组黏土岩中锂的赋存状态及其沉积环境进行研究。发现黏土矿物是锂的主要载体矿物,其主要包括锂绿泥石、伊利石和高岭石;锂含量与锂绿泥石含量呈显著正相关关系,与伊利石和高岭石的含量呈微弱的正相关关系;样品中的锂主要赋存于锂绿泥石的氢氧化物八面体晶格中,部分赋存于伊利石和高岭石中。古盐度指标m值(100×(MgO/Al_(2)O_(3)))和1000×Rb/k_(2)O值显示研究区富锂黏土岩主要形成于淡水—半咸水环境;古氧化还原指标V/(V+Ni)和Th/U值显示研究区富锂黏土岩主要形成于缺氧和贫氧环境;古气候指标Sr/Cu、C值((V+Cr+Mn+Fe+Co+Ni)/(Na+Mg+k+Ca+Sr+Ba))和CIA值显示研究区富锂黏土岩主要形成于炎热潮湿的古沉积环境中。该研究有助于完善沉积型锂矿的成矿理论,也有利于攻克该类型锂资源高效分离与提取的技术瓶颈。

关键词：锂赋存状态煤系黏土岩沉积环境晋南地区

Quercetin inhibits truncated isoform of dopamine-and cAMP-regulated phosphoprotein as adjuvant treatment for trastuzumab therapy resistance in HER2-positive breast cancer

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Food Science and Human Wellness 2024年第5期13卷 2653-2667页

作者： Han-Sheng Chang Tzu-Chun Cheng Shih-Hsin Tu Chih-Hsiung wu you-Cheng Liao Jungshan Chang Min-Hsiung Pan Li-Ching Chen yuan-Soon Ho Department of Biological Science&Technology College of Life SciencesChina Medical UniversityTaichung 406TaiwanChina Institute of Biochemistry and Molecular Biology College of Life SciencesChina Medical UniversityTaichung 406TaiwanChina Department of Surgery School of MedicineCollege of MedicineTaipei Medical UniversityTaipei 110TaiwanChina Department of Surgery Taipei Medical University HospitalTaipei 110TaiwanChina Graduate Institute of Medical Sciences College of MedicineTaipei Medical UniversityTaipei 110TaiwanChina Institute of Food Sciences and Technology National Taiwan UniversityTaipei 106TaiwanChina

Trastuzumab resistance is one of the causes of poor prognosis in patients with human epidermal growth factor receptor 2(HER2)-positive(HER2+)breast cancer(BC).The truncated isoform of dopamine-and cAMPregulated phosphoprotein(t-DARPP)has been reported to be involved in trastuzumab therapy resistance and promoting tumor *** evaluate the t-DARPP expression in BC,paired tumors and surrounding normal tissues were analyzed by real-time polymerase chain reaction and confirmed higher DARPP-32 kDa family mRNA expression in HER2+BC tumor *** established 2 patient-derived xenografts(PDX)mice models to test the efficacy of trastuzumab,named model 1(non-responder)and model 2(responder).t-DARPP and p95-HER2 protein-protein interactions were detected in PDX tumor tissue from non-responders using Förster resonance energy transfer ***,there is no response from the ***,mechanistic studies using transwell and western blot assays demonstrated that t-DARPP could upregulate epithelial-mesenchymal transition signaling proteins,enhance p95-HER2 expression and promote cell *** found that quercetin effectively reduced t-DARPP expression in HER2+BC *** t-DARPP ShRNA-suppressed cells,quercetin synergistically enhanced trastuzumab-induced apoptotic cell death and G2/M phase *** conclusion,the combination of quercetin and trastuzumab treatment by targeting t-DARPP in HER2+BC patients has the potential as a biomarker for mitigating drug resistance.

关键词： p95-Human epidermal growth factor receptor 2 (HER2) HER2-positive breast cancer Quercetin Trastuzumab resistance Truncated isoform of dopamine-and cAMPregulated phosphoprotein

Effects of Sodium Cyclohexyl Sulfamate on Growth and Development of Drosophila melanogaster

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Agricultural Biotechnology 2024年第4期13卷 65-69页

作者： Lei WEI Danni MA Guobao JIANG Jiayu wu Na FENG College of Life Science and Food Engineering Shaanxi Xueqian Normal UniversityXi'an 710100China

[Objectives]This study was conducted to investigate the effects of different concentrations of sodium cyclohexyl sulfamate on the growth and development of Drosophila melanogaster.[Methods]Different concentrations of sodium cyclohexyl sulfamate were added to the culture medium,and the effects of different concentrations of sodium cyclohexyl sulfamate on the development time and weight of *** in various life stages were statistically analyzed.[Results]High concentration of sodium cyclohexyl sulfamate delayed the time of pupation and eclosion of ***,which made *** lose *** number of male *** in the first generation was much larger than that of female individuals,which indicated that the effect of sodium cyclohexyl sulfamate on male *** was greater than that of female *** a word,high concentration of sodium cyclohexyl sulfamate significantly inhibited the growth and development of ***.[Conclusions]This study provides some reference data for the research perspective of food additives and the safe use of sodium cyclohexyl sulfamate.

关键词： Drosophila melanogaster Sodium cyclohexyl sulfamate Pupation Eclosion

Laryngeal leiomyoma:A case report and review of literature

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World Journal of Clinical Cases 2024年第18期12卷 3529-3533页

作者： yu wu Jing-Man Li Tian-Jiao Zhang Xin Wang Department of Otolaryngology Head and Neck SurgeryThe First Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina

BACkGROUND Leiomyomas(LMs)are mesenchymal tumors that arise from smooth muscle *** most commonly arise in organs with an abundance of smooth muscle such as the uterus and gastrointestinal ***,LMs are rarely detected in the head and neck *** this study,we report a rare case of laryngeal LM(LLM)and summarized the clinical characteristics of reported LLMs to help clinicians better understand this rare disease and improve its diagnosis,treatment,and postoperative *** SUMMARy A 49-year-old man was admitted to our ENT outpatient clinic with a chief complaint of pharynx discomfort for 2 *** performed under topical anesthesia revealed a solitary,pink mass at the tubercle of *** via laryngeal endoscopy was performed under general anesthesia,and the lesion was excised *** immunohistochemical staining for desmin and smooth-muscle actin indicated a smooth muscle origin and the diagnosis was laryngeal *** surgery,the patient’s condition was stable,and he was discharged 2 d after *** the 1-year postoperative period,the patient’s condition remained stable without evidence of *** Surgical resection is the preferred treatment for LLMs,its early diagnosis and differential diagnosis have important clinical significance.

关键词： Leiomyoma Larynx Smooth tumor Endoscopic surgery Case report