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Prophylactic Pattern Scanning Laser Retinal Photocoagulation for Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats: Preliminary Experimental Results

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Journal of Diabetes Mellitus 2024年第3期14卷 153-165页

作者： Rina Takagi yoshiaki Tanaka Tetsuya hasegawa Masami Shinohara yasushi Kageyama Tomohiko Sasase Machiko Shimmura-Tomita Akihiro Kakehashi Toshikatsu Kaburaki Department of Ophthalmology Saitama Medical Center Jichi Medical University Saitama-shi Saitama-ken Japan Tokyo Animal & Diet Department CLEA Japan Inc. Tokyo Japan Biological/Pharmacological Research Laboratories Central Pharmaceutical Research Institute Japan Tobacco Inc. Takatsuki Osaka Japan

Research Background and Purpose: The number of diabetic patients is rapidly increasing, making it crucial to find methods to prevent diabetic retinopathy (DR), a leading cause of blindness. We investigated the effects of prophylactic pattern scanning laser retinal photocoagulation on DR development in Spontaneously Diabetic Torii (SDT) fatty rats as a new prevention approach. Methods: Photocoagulation was applied to the right eyes of 8-week-old Spontaneously Diabetic Torii (SDT) fatty rats, with the left eyes serving as untreated controls. Electroretinography at 9 and 39 weeks of age and pathological examinations, including immunohistochemistry for vascular endothelial growth factor and glial fibrillary acidic protein at 24 and 40 weeks of age, were performed on both eyes. Results: There were no significant differences in amplitude and prolongation of the OP waves between the right and left eyes in SDT fatty rats at 39 weeks of age. Similarly, no significant differences in pathology and immunohistochemistry were observed between the right and left eyes in SDT fatty rats at 24 and 40 weeks of age. Conclusion: Prophylactic pattern scanning retinal laser photocoagulation did not affect the development of diabetic retinopathy in SDT fatty rats.

关键词： Diabetes Pattern Scanning Laser Diabetic Retinopathy Spontaneously Diabetic Torii Fatty Rats Electroretinography

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Novel procedure for hepatic venous outflow block after liver resection:A case report

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World Journal of Clinical Cases 2024年第29期12卷 6320-6326页

作者： Hisanobu Higashi yuta Abe Kodai Abe yutaka Nakano Masayuki Tanaka Shutaro Hori yasushi hasegawa Hiroshi yagi Minoru Kitago yuko Kitagawa Department of Surgery National Hospital Organization Saitama HospitalWako 351-0102Japan Department of Surgery Keio University School of MedicineTokyo 160-8582Japan

BACKGROUND Postoperative complications like remnant hepatic vein(HV)outflow block and liver torsion can occur after right *** falciform ligament fixation is typically used to prevent liver *** report a novel procedure to manage outflow *** SUMMARy An 80-year-old man developed HV outflow block after remnant right hepatectomy,despite liver fixation and intraoperative HV flow *** had a history of cholangiocellular carcinoma and had undergone posterior segmentectomy and *** falciform ligament fixation was inadequate to maintain liver *** surgery was performed,using an omental flap and mobilized right side colon with ileocecal region to prevent liver dislocation due to intraabdominal *** postoperative course was *** This is the first report providing a novel surgical procedure when the falciform ligament is insufficient for remnant liver fixation.

关键词： Hepatectomy Postoperative complications Budd-Chiari syndrome Hepatic vein outflow block Emergency surgery Case report

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Complex-Valued Neural Networks:A Comprehensive Survey

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IEEE/CAA Journal of Automatica Sinica 2022年第8期9卷 1406-1426页

作者： Chiyan Lee Hideyuki hasegawa Shangce Gao Faculty of Engineering University of ToyamaToyama 930-8555Japan

Complex-valued neural networks(CVNNs)have shown their excellent efficiency compared to their real counterparts in speech enhancement,image and signal *** throughout the years have made many efforts to improve the learning algorithms and activation functions of *** CVNNs have proven to have better performance in handling the naturally complex-valued data and signals,this area of study will grow and expect the arrival of some effective improvements in the ***,there exists an obvious reason to provide a comprehensive survey paper that systematically collects and categorizes the advancement of *** this paper,we discuss and summarize the recent advances based on their learning algorithms,activation functions,which is the most challenging part of building a CVNN,and ***,we outline the structure and applications of complex-valued convolutional,residual and recurrent neural ***,we also present some challenges and future research directions to facilitate the exploration of the ability of CVNNs.

关键词： Complex activation function complex backpropagation algorithm complex-valued learning algorithm complex-valued neural network deep learning

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Reproducibility and Validity of a Chinese Food Frequency Questionnaire

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Biomedical and Environmental Sciences 2010年第S1期23卷 1-38页

作者： Water WILLETT Kyoko hasegawa Department of Nutrition Harvard School of Public Health Kagawa Nutrition University

Objectives This study was design to develop a semi-quantitative Chinese Food Frequency Questionnaire （FFQ） and to conduct a validation study for the questionnaire. Methods Based on the survey experience in recent years, a new Chinese food frequency questionnaire （FFQ） with 149 items in 17 food categories was developed. A validation study on this new FFQ was conducted in Jiangsu and Beijing of China between 1999 and 2001. The period of study covered 1 year and the FFQ was validated by comparing with data obtained by a six repeated 24-hour recalls for 3 consecutive days, or a totally 18-day 24- hour recall throughout the year. A total of 271 healthy adult subjects were enrolled in the study. Food and nutrient intakes measured by the 18-day dietary recalls and food frequency questionnaires （FFQs） were computed in the National Institute for Nutrition and Food Safety, China CDC using the existing nutrition database. The average daily intake of foods and nutrients over the 18-day recall was used to compare with FFQ1 and FFQ2, which was conducted at the beginning and the end of the year, respectively. All statistical analyses were carried out using SAS software version 6.12.

关键词： FFQ Reproducibility and Validity of a Chinese Food Frequency Questionnaire

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A technique utilizing chemical reagents for direct measurement of temperature at a local area and its engineering applications

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Acta Mechanica Sinica 2009年第2期25卷 149-160页

作者： M.Saka T.hasegawa Department of Nanomechanics Tohoku University

Temperature is one of the physical quantifies through which quantitative evaluation of the safety and reliability of industrial products can be achieved, and this has been used widely in practice. Under any environmental condifion, regardless of the size of the object to be inspected, accurate and reliable measurement of temperature is of great practical importance. This review article presents a simple and direct method of temperature measurement, that can be applied to the local areas with difficulty in measuring the temperature by using normal thermometers. In the present article, two different application examples are demonstrated. One addresses the study of the electromigration of solders which are used as bonding metals in electronic devices （micro-structures）. The application of the method to the shaft of a motor used in heavy industrial fields is explained as the second.

关键词： Temperature measurement Chemicalreagents Melting point Temperature distribution

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Retinal ganglion cell protection by hop-flower extract as a novel neuroprotective strategy for glaucoma

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Neural Regeneration Research 2022年第6期17卷 1267-1268页

作者： Tomoko hasegawa Hanako Ohashi Ikeda Department of Ophthalmology and Visual Sciences Kyoto University Graduate School of MedicineKyotoJapan Research Fellow of Japan Society for the Promotion of Science TokyoJapan

In glaucoma,a leading cause of blindness,retinal ganglion cells are progressively *** pressure reduction is the only established treatment for glaucoma(Collaborative Normal-Tension Glaucoma Study Group,1998;Vass et al.,2007).However,in some cases,visual field loss progresses despite sufficiently reduced intraocular pressure(Collaborative Normal-Tension Glaucoma Study Group,1998;Killer and Pircher,2018).While intraocular pressure and age are known risk factors for glaucoma(Ernest et al.,2013),the underlying mechanisms of glaucoma progression are not fully understood.

关键词： glaucoma al. protective

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NUMERICAL SIMULATION ON COMPRESSIBLE TURBULENCE By SPECTRAL METHOD

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Acta Mechanica Sinica 1998年第3期14卷 193-207页

作者：王健平 Tatsuya hasegawa State Key Laboratory for Turbulence Research Department of Mechanics and Engineering SciencePeking UniversityBeijing 100871China Department of Mechanical Engineering Nagoya Institute of TechnologyGokiso-choShowa-kuNagoya 466Japan

The numerical and physical issues of simulations on compressible turbulence are reviewed in the present paper. An outline of the global spectral methods and the progress of recent local spectral methods are illustrated. Several typical subjects in this field are studied, including homogeneous isotropic turbulence, autoignition in premixed turbulence, interaction between flames and turbulence, and shock wave in turbulence. The results of the numerical simulations are discussed, enabling us to discover and to understand the physical phenomena which have not been solved by experiments.

关键词： compressible turbulence turbulent flame spectral method

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Effect of additional element and heat treating temperature on micro-structure and mechanical behavior of Ag alloy thin film

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中国有色金属学会会刊：英文版 2006年第B1期16卷 217-219页

作者： ISHIGURO S A RIZONO T hasegawa K Department of Material Science and Engineering Saitama Institute of TechnologyFusaiji 1690OkabeSaitamaJapan 369-0293 Ishifuku Metal Industry Co Ltd Kana 3-20-7Chiyoda-kuTokyoJapan

For Ag alloy film used for the storage media, it is required to have heat-resistance, anti-constant temperature and anti-constant humidity characteristics, corrosion resistance, while high reflectivity over Al is maintained. An Ag alloy thin film (additive element Pd, Cu, P) was created on glass substrates, and various heat treatment was conducted. Then, fine structure was observed on this thin film using AFM, and fine structure evaluation of the inside was carried out by the in-plane diffractometry and X-ray diffractometry, and in addition, residual stress analysis was carried out. These results were compared and were examined, and fine structure and physical property in a metallic thin film were evaluated, and usefulness of evaluation method was verified.

关键词：银合金薄膜添加元素热处理温度显微结构力学行为

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Prevalence and characteristics of Kawasaki disease before and during the COVID-19 pandemic

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World Journal of Pediatrics 2021年第2期17卷 215-217页

作者： Rintaro Ono Daisuke hasegawa Department of Pediatrics St.Luke's International Hospital9-1 AkashichoChuo-kuTokyo 104-8560Japan

Kawasaki disease(KD)is a febrile disease with unclear *** far,KD has been considered to be trig-gered,at least in part,by an infection[1].In 2020,corona-virus disease 2019(COVID-19)became a global pandemic and lifestyles changed ***,the preva-lence of common infection has decreased *** epidemiological change prompted us to postulate that major variations of common pediatric infections would affect the incidence of KD.

关键词： prompt characteristics Kawasaki

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Synthesis of a stroboscopic image from a hand-held camera sequence for a sports analysis

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Computational Visual Media 2016年第3期2卷 277-289页

作者： Kunihiro hasegawa Hideo Saito Keio University

This paper presents a method for synthesizing a stroboscopic image of a moving sports player from a hand-held camera sequence. This method has three steps: synthesis of background image,synthesis of stroboscopic image, and removal of player's shadow. In synthesis of background image step, all input frames masked a bounding box of the player are stitched together to generate a background image. The player is extracted by an HOG-based people *** synthesis of stroboscopic image step, the background image, the input frame, and a mask of the player synthesize a stroboscopic image. In removal of shadow step, we remove the player's shadow which negatively affects an analysis by using mean-shift. In our previous work, synthesis of background image has been timeconsuming. In this paper, by using the bounding box of the player detected by HOG and by subtracting the images for synthesizing a mask, computational speed and accuracy can be improved. These have contributed greatly to the improvement from the previous *** are main improvements and novelty points from our previous method. In experiments, we confirmed the effectiveness of the proposed method, measured the player's speed and stride length, and made a footprint image. The image sequence was captured under a simple condition that no other people were in the background and the person controlling the video camera was standing still, such like a motion parallax was not occurred. In addition, we applied the synthesis method to various scenes to confirm its versatility.

关键词： sports vision stroboscopic image stitching mask synthesis

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