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Frontiers in Energy 2021年第2期15卷 499-512页

作者： xueqing liu Xiaodong ZHAO Luyi LU Jianlan LI School of Energy and Power Engineering Huazhong University of Science and TechnologyWuhan 430074China

Solar energy is one of the most promising forms of renewable energy for solving the energy crisis and environmental problems. Dust deposition on photovoltaic mirrors has a serious negative impact on the photoelectric conversion efficiency of solar power stations. In this paper, the influence mechanism of the dynamic and static liquid bridge forces on particle deposition behaviors on solar photovoltaic mirrors is investigated. In addition, the expression and physical meaning of the particle critical separation velocity are proposed. The research results show that the static liquid bridge force can be the primary deposition force causing dust particles to adhere to photovoltaic mirrors. However, the dynamic liquid bridge force can act as a resistance force for the particle motion process and even make dust particles roll along and finally stay on the mirror. The contact force is the primary separation force that causes dust particles to flow away from the mirror. Whether dust particles adhere to the mirror depends on the relative size of the deposition and separating forces. The particle critical separation velocity describes the relative size of the collision-rebound effect and mirror adhesion effect and is expressed in Eq. (16). These research findings can provide theoretical guidance for mirror cleaning methods in the operation process of photovoltaic mirrors.

关键词： dust deposition discrete element method(DEM) photovoltaic mirrors solar energy

Preparing 3D Perovskite Li_(0.33)La_(0.557)TiO_(3)Nanotubes Framework Via Facile Coaxial Electro-Spinning Towards Reinforced Solid Polymer Electrolyte

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Energy & Environmental Materials 2023年第4期6卷 273-279页

作者： Yichun Zhao Lin Fan Biao Xiao Shaojun Cai Jingchao Chai xueqing liu Jiyan liu Zhihong liu Department of Polymer Material and Engineering Jianghan UniversityWuhan 430056China Key Laboratory of Optoelectronic Chemical Materials and Devices Ministry of EducationJianghan UniversityWuhan 430056China Flexible Display Materials and Technology Co-innovation Centre of Hubei Province Jianghan UniversityWuhan 430056China

It is of significance to construct continuous multiphase percolation channels with fast lithium-ion pathway in hybrid solid electrolytes.3D ceramic nanostructure frameworks have attracted great attention in this ***,the three-dimensional perovskite Li_(0.33)La_(0.557)TiO_(3)nanotubes framework(3D-LLTO-NT)is fabricated via a facile coaxial electro-spinning process followed by a calcination process at 800°*** hybrid polymer electrolyte of 3DLLTO-NT framework and poly(ethylene carbonate)(3D-LLTO-NT@PEC)shows improved ionic conductivity of 1.73×10^(-4)S cm^(-1)at ambient temperature,higher lithium-ion transference number(t_(Li)^(+))of 0.78 and electrochemical stability window up to 5.0 V vs Li/Li^(+).The all-solid-state cell of LiFePO_(4)/3D-LLTO-NT@PEC/Li delivers a high specific capacity of 140.2 mAh g^(-1)at 0.1 C at ambient *** outstanding performance is attributed to the 3D ceramic nanotubes frameworks which provide fast lithium ion transfer pathway and stable interfaces.

关键词： coaxial electro-spinning ion conductivity Li_(0.33)La_(0.557)TiO_(3) nanotubes solid composite electrolyte

Impact of Model Bias Correction on a Hybrid Data Assimilation System

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Journal of Meteorological Research 2020年第2期34卷 400-412页

作者： Yu XIA Jing CHEN Xiefei ZHI Lianglyu CHEN Yang ZHAO xueqing liu Nanjing University of Information Science&Technology Nanjing 210044 Numerical Weather Prediction Center China Meteorological AdministrationBeijing 100081 Chongqing Institute of Meteorological Sciences Chongqing 401147 State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081 Zhejiang Institution of Meteorological Sciences Hangzhou 310016

Hybrid data assimilation combines a conventional 3-D or 4-D variational system with background error covariance(BEC)generated from ensemble forecast *** order to achieve better BEC,three perturbation schemes,namely,the random combination of multiple physical paramterization schemes(referred to as MP),the MP plus stochastical perturbation on physical process tendencies(MP-SPPT),and the unified perturbation of stochastic physics with bias correction(UPSB,proposed by the authors of this paper in a previous work),were first used in a regional ensemble model,i.e.,the Global and Regional Assimilation and Prediction System-Regional Ensemble Prediction System(GRAPES-REPS),and the BECs thus obtained were compared for 7-day ensemble *** results show that UPSB,which is in fact an MP-SPPT but with the systematic model bias removed,has a better consistency,i.e.,the ratio between root-mean-square error(RMSE)and ensemble spread is much closer to 1,especially at low model levels,compared to the other two ***,the BEC derived from UPSB captured more reasonable distributions of forecast ***,performance of a hybrid data assimilation system(the GRAPES-MESO hybrid En-3DVar)was evaluated by using the BECs from the three perturbation schemes for 7-day hybrid data assimilation forecasts,and thus disclosing the effect of the model bias correction(assuming that the random stocastical features are in general offset in the three perturbation schemes)on the hybrid system forecasts.A covariance weight of 0.8 was prescribed,and this value was determined through sensitivity *** forecast results from the hybrid data assimilation system show that UPSB reduced the false correlation between distant *** quality of analysis fields of the UPSB scheme shows visible improvement,i.e.,the analysis fields produced by UPSB have much smaller RMSEs than those of the other two schemes,at all vertical model *** quality of the hybrid data assimilation

关键词： ensemble perturbation hybrid data assimilation background error covariance(BEC) model systematic bias stochastical perturbation on physical process tendencies(SPPT)

TGR5 deficiency activates antitumor immunity in non-small cell lung cancer via restraining M2 macrophage polarization

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Acta Pharmaceutica Sinica B 2022年第2期12卷 787-800页

作者： Lifang Zhao Hongyan Zhang xueqing liu Shan Xue Dongfang Chen Jing Zou Handong Jiang Department of Respiratory and Critical Care Medicine Ren Ji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China

The bile acid-responsive G-protein-coupled receptor TGR5 is expressed in monocytes and macrophages,and plays a critical role in regulating inflammatory *** previous work has shown its role in promoting the progression of non-small cell lung cancer(NSCLC),yet the mechanism remains ***,using Tgr5-knockout mice,we show that TGR5 is required for M2 polarization of tumorassociated macrophages(TAMs)and suppresses antitumor immunity in NSCLC via involving TAMsmediated CD8+T cell ***,we demonstrate that TGR5 promotes TAMs into protumorigenic M2-like phenotypes via activating c AMP-STAT3/STAT6 *** of c AMP production restores M2-like phenotypes in TGR5-deficient *** NSCLC tissues from human patients,the expression of TGR5 is associated with the infiltration of *** co-expression of TGR5 and high TAMs infiltration are associated with the prognosis and overall survival of NSCLC ***,this study provides molecular mechanisms for the protumor function of TGR5 in NSCLC,highlighting its potential as a target for TAMs-centric immunotherapy in NSCLC.

关键词： TGR5 Bile acids Tumor-associated macrophages(TAMs) Tumor microenvironment(TME) Non-small cell lung cancer(NSCLC) Antitumor immunity Immunotherapy c AMP-STAT3/STAT6

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脑灰质异位症研究进展

中国实用神经疾病杂志 2025年第1期28卷 109-113页

作者：刘雪晴赵娜岳伟杨丽琴丁朋天津医科大学神经内外科及神经康复临床学院天津300070 天津市环湖医院天津300350

脑灰质异位症可由遗传、辐射、药物等多种因素导致,其特征为正常神经元异常聚集于脑皮质以外的部位。依据异位灰质的形态及部位,可将脑灰质异位症分为脑室周围灰质异位、皮质下带状灰质异位和皮质下灰质异位。脑灰质异位症的临床表现包... 详细信息

脑灰质异位症可由遗传、辐射、药物等多种因素导致,其特征为正常神经元异常聚集于脑皮质以外的部位。依据异位灰质的形态及部位,可将脑灰质异位症分为脑室周围灰质异位、皮质下带状灰质异位和皮质下灰质异位。脑灰质异位症的临床表现包括癫痫、智力缺陷、认知及语言障碍等。磁共振成像为诊断脑灰质异位症的首选检查手段。目前,脑灰质异位症相关性癫痫的治疗多为药物治疗与手术治疗。近年来,立体脑电图引导的射频热凝越来越受到重视,针对认知、运动、语言的康复训练亦有利于改善患者的生活质量。

关键词：脑灰质异位症遗传学癫痫智力缺陷认知障碍语言障碍康复训练磁共振成像立体脑电图引导的射频热凝

NCAPD2 serves as a potential prognostic biomarker for lung adenocarcinoma and promotes cell proliferation,migration,invasion and cell cycle in vitro

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Oncology Research 2024年第9期32卷 1439-1452页

作者： PEILING WU LIFANG ZHAO HONGYAN ZHANG YUEYAN LOU DONGFANG CHEN SHAN XUE xueqing liu HANDONG JIANG Department of Respiratory and Critical Care Medicine Renji HospitalShanghai Jiao Tong University School of MedicineShanghai200127China

Objectives:The pro-oncogenic effects of NCAPD2 have been extensively studied across various tumor types;however,its precise role within the context of lung adenocarcinoma(LUAD)remains *** study aims to elucidate the biological functions of NCAPD2 in LUAD and unravel the underlying mechanistic ***:Utilizing bioinformatics methodologies,we explored the differential expression of NCAPD2 between normal and tumor samples,along with its correlations with clinical-pathological characteristics,survival prognosis,and immune ***:In the TCGA-LUAD dataset,tumor samples demonstrated significantly elevated levels of NCAPD2 expression compared to normal samples(p<0.001).Clinically,higher NCAPD2 expression was notably associated with advanced T,N,and M stages,pathologic stage,gender,smoking status,and diminished overall survival(OS).Moreover,differentially expressed genes(DEGs)associated with NCAPD2 were predominantly enriched in pathways related to cell *** infiltration analysis revealed that NCAPD2 expression levels were linked to the infiltration of memory B cells,naïve CD4+T cells,activated memory CD4+T cells,and M1 *** vitro experiments demonstrated that silencing NCAPD2 suppressed LUAD cell proliferation,migration,invasion,epithelial-mesenchymal transition(EMT),and cell cycle ***:In summary,NCAPD2 may represent a promising prognostic biomarker and novel therapeutic target for LUAD.

关键词： NCAPD2 LUAD Prognosis Immune infiltration Cell cycle

CircRNA expression profiles in decidual tissue of patients with early recurrent miscarriage

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Genes & Diseases 2020年第3期7卷 414-423页

作者： Chunli Li Xuemei Chen xueqing liu Xiaoli liu Junlin He Yubin Ding Chao Tong Chuan Peng Yingxiong Wang Rufei Gao Laboratory of Reproductive Biology School of Public Health and ManagementChongqing Medical UniversityChongqing400016China Department of Clinical Laboratory Chongqing Health Center for Women and ChildrenChongqing401174China Joint International Research Laboratory of Reproduction&Development Chongqing Medical UniversityChongqing400016China Department of Family Planning Chongqing Health Center for Women and ChildrenChongqing401174PR China Department of Obstetrics The First Affiliated Hospital of Chongqing Medical UniversityChongqing400016China Laboratory of Maternal and Fetal Medicine The First Affiliated Hospital of Chongqing Medical UniversityChongqing400016China

Circular RNAs(circRNAs)are a novel class of endogenous noncoding RNAs that play important roles in gene expression *** study aimed to evaluate the potential role of circRNAs in decidual tissue of patients with early recurrent miscarriage(RM).We constructed circRNA expression profiles in decidual tissue using microarray data.A total of 123 differentially expressed circRNAs,including 78 upregulated and 45 downregulated circRNAs were detected in the early RM group compared with the control group(P<0.05).Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis also revealed the enrichment of specific *** verified circRNA-targeted miRNA-mRNA network was constructed,most of the circRNAs harbored miRNA binding *** network involved 3 circRNAs,27 microRNAs and 82 ***_circRNA_103092-miR-224-PRLR network was selected to verify by *** results showed that circRNAs are aberrantly expressed in the decidual tissue in early RM patients and play potential roles in the development of early *** gives new insights into the mechanism of recurrent miscarriage.

关键词： Circular RNAs Decidual tissue Early recurrent miscarriage Expression profiles Microarray

Electrocatalytic cleavage of a lignin β-O-4 model compound and coupling with nitrogen-containing aromatics using Prussian blue analogue-derived nickel–cobalt spinel

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Journal of Energy Chemistry 2025年第1期100卷 628-636页

作者： Yi Qi Xueying Chen Bowen liu Xuliang Lin xueqing Qiu Yanlin Qin Guangdong Provincial Key Laboratory of Plant Resources Biorefinery School of Chemical Engineering and Light Industry Guangdong University of Technology Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center Guangdong Basic Research Center of Excellence for Ecological Security and Green Development Guangdong University of Technology

Electrochemical conversion of lignin for the production of high-value heterocyclic aromatic compounds has great *** demonstrate the targeted synthesis and cation modulation of NiCo2O4spinel nanoboxes,synthesized via cation exchange and calcination *** catalysts exhibit excellent efficacy in the electrocatalytic conversion of lignin model compounds,specifically 2-phenoxy-1-phenylethanol,into nitrogen-containing aromatics,achieving high conversion rates and *** catalysts were synthesized via a cation exchange and calcination oxidation process,using Prussian blue nanocubes as *** porous architecture and polymetallic composition of the NiCo2O4spinel demonstrated superior performance in electrocatalytic oxidative coupling,achieving a 99.2 wt%conversion rate of the 2-phenoxy-1-phenylethanol with selectivities of 37.5 wt%for quinoline derivatives and 31.5 wt%for *** innovations include the development of a sustainable one-pot synthesis method for quinoline derivatives,the elucidation of a multistage reaction pathway involving CAO bond cleavage,hydroxyaldol condensation,and CAN bond formation,and a deeper mechanistic understanding derived from DFT *** work establishes a new strategy for lignin valorization,offering a sustainable route to produce high-value nitrogen-containing aromatics from renewable biomass under mild conditions,without the need for additional reagents.

关键词： Spinel Biomass valorization Electrocatalysis Lignin oxidation Coupling

Study on Calculation Method of Compressional Velocities Based on Field Well Logs

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International Journal of Geosciences 2016年第7期7卷 928-937页

作者： Feizhou Shi Yanchun Wang xueqing liu School of Geophysics and Information Technology China University of Geosciences (Beijing) Beijing China

In the past, most of the studies for compressional velocities are based on experimental measurements, which lack the support of field data. The purpose of this study is to estimate the compressional velocities based on well log data of delta front subfacies of Lower Tertiary ages of Ji-Dong oil field, China. At initial stage, we have chosen the well log parameters (effect factors) which strongly influence on compressional velocities and established a new modified equation for compressional velocities, which is based on these effect factors. Then Gardner, De-hua Han and this newly established equation were utilized to calculate the compressional velocities in each well. Finally, Least-square regression was carried out to check the fitting of each equation. Regression results clearly indicate that our purposed equation shows better fitting as compared to Gardner and De-hua Han equations.

关键词： Compressional Velocities Well Logs Calculation Method

Trend,seasonal and diurnal variations of atmospheric CO_2 in Beijing

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Chinese Science Bulletin 2002年第24期47卷 2050-2055页

作者： WANG Yuesi, WANG Changke, GUO xueqing, liu Guangren & HUANG YaoLAPC, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100083, China Department of Chemistry, Capital Normal University, Beijing 100037, China LAPC Institute of Atmospheric Physics Chinese Academy of Sciences Beijing China Department of Chemistry Capital Normal University Beijing China

The concentration of atmospheric CO2 in Beijing increased rapidly at a mean growth rate of 3.7%·a-1 from 1993 to 1995. After displaying a peak of (409.7±25.9) μmol·mol-1 in 1995, it decreased slowly. Both the almost stable anthropogenic CO2 source and increasing biotic CO2 sink contribute to the drop of CO2 concentration from 1995 to 2000. The seasonal variation of CO2 concentration exhibits a clear cycle with a maximum in winter, averaging (426.8± 20.6)μmol·mol-1, and a minimum in summer, averaging (369.1±6.1)μmol·mol-1. The seasonal variation of CO2 concentration is mainly controlled by phenology. The mean diurnal variation of atmospheric CO2 concentration for a year in Beijing is highly clear: daily maximum CO2 concentration usually occurs at night, but daily minimum CO2 concentration does in the daytime, with a mean diurnal difference more than 34.7μmol·mol-1. It has been revealed that the interannual variations of atmospheric CO2 concentration in winter and autumn regulated the

关键词： atmospheric CO2 annual variation seasonal variation diurnal variation urban environment.