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中国循证医学杂志 2011年第1期11卷 2-6页

作者：李幼平刘雪梅四川大学华西医院中国循证医学中心成都610041 四川大学华西医院华西期刊社成都610041

1系统评价的概念系统评价最早源于研究合成（research synthesis）。早在1753年,苏格兰航海外科医生James lind就意识到研究合成在解释结果中减少偏倚的重要性。

关键词：系统外科医生苏格兰合成

Increased 5-hydroxymethylcytosine is a favorable prognostic factor of Helicobacter pylori-negative gastric cancer patients

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World Journal of Gastrointestinal Oncology 2022年第7期14卷 1295-1306页

作者： Ying-li Fu Yan-Hua Wu Dong-Hui Cao Zhi-Fang Jia Ao Shen Jing Jiang xue-Yuan Cao Division of Clinical Research The First Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina Department of Gastric and Colorectal Surgery The First Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina

BACKGROUND Most gastric cancer(GC)patients are diagnosed at middle or late stage because the symptoms in early stage are obscure,which causes higher mortality rates of *** pylori(***)was identified as a class I carcinogen and leads to aberrant DNA methylation/hydroxymethylation.5-hydroxymethylcytosine(5-hmC)plays complex roles in gene regulation of tumorigenesis and can be considered as an activating epigenetic mark of *** To explore the association between 5-hmC levels and the progression and prognosis of GC patients with or without *** *** A retrospective cohort study was conducted to estimate the predicted value of 5-hmC level in the progression and prognosis of GC patients with different *** infection status.A total of 144 GC patients were *** The levels of 5-hmC were significantly decreased in tumor tissues(0.076±0.048)compared with the matched control tissues(0.110±0.057,P=0.001).A high level of 5-hmC was an independent significant favorable predictor of overall survival in GC patients(hazard ratio=0.61,95% confidence interval:0.38-0.98,P=0.040),the ***-negative GC subgroup(hazard ratio=0.30,95% confidence interval:0.13-0.68,P=0.004)and the GC patients with TNM stage Ⅰ or Ⅱ(hazard ratio=0.32,95% confidence interval:0.13-0.77,P=0.011).CONCLUSION Increased 5-hmC is a favorable prognostic factor in GC,especially for ***-negative subgroups.

关键词： 5-hydroxymethylation 5-hydroxymethylcytosine Helicobacter pylori Gastric cancer Prognosis

Construction of [Cu_nI_n]-based coordination polymers via flexible benzimidazolyl-based ligands

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Science China Chemistry 2010年第10期53卷 2083-2090页

作者： li lingling, REN ZhiGang, Lü xue, WANG HeMing, CHANG YuJie, li HongXi, WU Bing & LANG JianPing College of Chemistry, Chemical Engineering and Materials Science, Suzhou University, Suzhou 215123, China College of Chemistry Chemical Engineering and Materials Science Suzhou University Suzhou China

Four new [CunIn]-based coordination polymers, [{Cu4(μ3-I)4(mbbm)2}·2DMF]n (1), [(CuI)2(mbbm)2]n (2), [{Cu2(μ-I)2-(ebbm)2}·2MeCN]n (3), and [Cu2(μ-I)2(prbbm)2]n (4), were prepared from solvothermal reactions of CuI with three flexible ligands [(bzim)(CH2)n(bzim)] (bzim = benzimidazole; n = 1, mbbm; n = 2, ebbm; n = 3, prbbm). These compounds were characterized by elemental analysis, IR and X-ray crystallography. 1 consists of cubanelike [Cu4(μ3-I)4] fragments that link the neighboring ones via mbbm bridges to form a 1D ladder-type chain. 2 contains mononuclear [CuI] fragments that are bridged by mbbm ligands to yield a 1D zigzag chain. 3 or 4 contains a [Cu2(μ-I)2] dimeric fragment, which works as a four-connecting node to link its four equivalent ones to form a 2D (4,4) network (3) or acts as a two-connecting node to connect its two equivalent ones via two pairs of prbbm bridges to form a 1D double chain (4). The photoluminescent properties of 1-4 in the solid state at ambient temperature were investigated.

关键词： coordination polymers assembly flexible ligands solvothermal reactions photoluminescent properties

Characteristic of red eye related diseases of Han and Uygur population in Urumchi compared with Shanghai, China

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International Journal of Ophthalmology(English edition) 2022年第7期15卷 1165-1173页

作者： Hui Zhao Yi Shao Shi-Nan Wu li-Ying Tang Qi Zhang Chen Zhao xue-Yi Chen Jing Fu Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200092China Department of Ophthalmology the First Affiliated Hospital of Nanchang UniversityJiangxi Province Ocular Disease Clinical Research CenterNanchang 330006Jiangxi ProvinceChina Eye Institute of Xiamen University Xiamen 361102Fujian ProvinceChina The First Affiliated Hospital of Xin Jiang Medical University Urumqi 830011Xinjiang Uygur Autonomous RegionChina

AIM: To study the characteristics, relative distribution and to compare causes of red eye in ophthalmic clinics in Urumchi and Shanghai, ***: Data on continuous cases of red-eye patients admitted to the Ophthalmology Center of Xinhua Hospital Affiliated to Shanghai Jiao Tong University and the First Affiliated Hospital of Xinjiang Medical University were collected between November 2018 and September 2019. Demographic data, the incidence of red eye and related disease distribution of all cases were obtained. The independent t-test method was used for age comparison, while the Chi-square test was used to compare classified data ***: The information on 335 and 415 patients with red eyes in Shanghai and Urumchi were collected, respectively. The main causes of red eye were conjunctival disease and dry eye. The age of female patients with red eyes was significantly higher than that of males, and the proportion of female patients with dry eyes was also ***-eye-related diseases occurred more frequently in patients over 46 years old than in those under 18, and dry eye was more common with increasing age. The incidence of infectious conjunctivitis in Urumchi was significantly higher than that in Shanghai, and allergic conjunctivitis occurred more frequently in spring, summer, or autumn than in winter(all P<0.05).CONCLUSION: Significant differences exist in the distribution of red-eye-related diseases in Urumchi and Shanghai regions of China, and distribution varies with age and season, the latter being an important feature of allergic conjunctivitis.

关键词： distribution red-eye-related diseases characteristic

Experimental and numerical studies of titanium foil/steel explosively welded clad plate

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Defence Technology（防务技术） 2023年第7期25卷 192-202页

作者： Zhi-xiong Bi xue-jiao li Ke Yang Rong Kai Quan Wang Meng-ben Xu Ting-zhao Zhang Xian-de Dai Jing-ye Qian Yong Wu School of Civil Engineering Anhui University of Science and TechnologyHuainanAnhui232001PR China School of Chemical Engineering Anhui University of Science and TechnologyHuainanAnhui232001PR China School of Mining Engineering Anhui University of Science and TechnologyHuainanAnhui232001PR China

Ti/Fe clad plate had attracted extensive attention because of its important application. In order to reduce the titanium layer thickness, the explosive welding of TA1 titanium foil to Q235 steel plate was carried out. The interfacial bonding performance was analyzed by micromorphology analysis and mechanical property test, and the formation process of interfacial wave and molten block in the vortex was simulated by smoothed particle hydrodynamics(SPH) method. The results showed that salt as pressure transfer layer used in explosive welding could play a good buffer effect on the collision between flyer and base layers. Regular waveforms were formed on the bonding interface, and the titanium foil/steel clad plate exhibited good welding quality and bonding property. The crest of the observed interfacial wave moved 200 μm from the beginning to the final formation, and it was important of jet on the formation of interfacial waveform. The interface was mainly bonded in the form of molten layer, and the grains near the interface were streamlined. Molten block containing intermetallic compounds and metal oxides appeared in the vortex of wave crest.

关键词： Explosive welding Pressure transfer layer Titanium foil Simulation Bonding property

Three new Cu(Ⅱ)-Ln(Ⅲ) heterometallic coordination polymers constructed from quinolinic acid and nicotinic acid: Synthesis, structures, and magnetic properties

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中国科学:化学 2012年第6期42卷 933-934页

作者： liU SuiJun SONG WeiChao xue li HAN SongDe ZENG YongFei WANG liFu BU XianHe Department of Chemistry Tianjin Key Laboratory of Metal & Molecule-based Material Chemistry Nankai University Tianjin 300071 China

Three new Cu(II)-Ln(Ⅲ) heterometallic coordination polymers based on two N-heterocyclic carboxylic ligands, {[LnCu(L1)2(L2)(H2O)2]·mH2O}n (Ln = La(1), Nd(2), Gd(3), m = 2 (for 1), 1 (for 2, 3), H2L1 = quinolinic acid, HL2 = nicotinic acid), have been synthesized and characterized. 1 has a two-dimensional (2D) layer structure with a Schl?fli symbol of (44.62), while complexes 2 and 3 are isostructural and have three-dimensional (3D) structures with a Schl?fli symbol of (3.4.5)2(32.***.52.614.***.83.9)(32.63.7) of 3-nodal net. Magnetic investigations suggest that antiferromagnetic coupling exists between NdⅢ and CuII in 2, while weak ferromagnetic coupling between GdⅢ and CuII in 3. The difference of magnetic properties between 2 and 3 has been discussed.

关键词：配位聚合物磁学性质层结构喹啉酸烟酸合成反铁磁耦合构造

Dynamical Complexity Analysis in a Model of Electroencephalogram

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Chinese Journal of Biomedical Engineering(English Edition) 2017年第1期26卷 5-10页

作者： li Chun-sheng ZHANG xue School of Electrical Engineering Shenyang University of Technology School of Science Northeastern University

This paper studies a dynamical model of electroencephalogram(EEG).By linearizing the EEG model conditions for the stability of equilibrium point are obtained. Choosing excitatory inputs as bifurcation parameters, numerical simulations show that the EEG model exhibits a series of complex dynamics, including limit cycle,periodic doubling bifurcation, periodic halving bifurcation, chaotic bands with periodic windows.

关键词： EEG dynamical model stability bifurcation diagram Lyapunov exponent chaos

Precision measurement of the Newtonian gravitational constant

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National Science Review 2020年第12期7卷 1803-1817页

作者： Chao xue Jian-Ping liu Qing li Jun-Fei Wu Shan-Qing Yang Qi liu Cheng-Gang Shao liang-Cheng Tu Zhong-Kun Hu Jun Luo Tian Qin Research Center for Gravitational Physics & School of Physics and Astronomy Sun Yat-sen University(Zhuhai Campus) MOE Key Laboratory of Fundamental Physical Quantities Measurement & Hubei Key Laboratory of Gravitation and Quantum Physics PGMF and School of PhysicsHuazhong University of Science and Technology

The Newtonian gravitational constant G,which is one of the most important fundamental physical constants in nature,plays a significant role in the fields of theoretical physics,geophysics,astrophysics and *** G was the first physical constant to be introduced in the history of science,it is considered to be one of the most difficult to measure accurately so *** the past two decades,eleven precision measurements of the gravitational constant have been performed,and the latest recommended value for G published by the Committee on Data for Science and Technology(CODATA) is(6.674 08 ±0.000 31) × 10m~3 kgswith a relative uncertainty of 47 parts per *** uncertainty is the smallest compared with previous CODATA recommended values of G;however,it remains a relatively large uncertainty among other fundamental physical *** this paper we briefly review the history of the G measurement,and introduce eleven values of G adopted in CODATA 2014 after 2000 and our latest two values published in 2018 using two independent methods.

关键词： precision measurement Newtonian gravitational constant CODATA

KOH-assisted aqueous synthesis of ZIF-67 with high-yield and its derived cobalt selenide/carbon composites for high-performance li-ion batteries

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Chinese Journal of Chemical Engineering 2023年第5期57卷 214-223页

作者： Kai xue Yanchun xue Jing Wang Shuya Zhang Xingmei Guo Xiangjun Zheng Fu Cao Qinghong Kong Junhao Zhang Zhong Jin School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China MOE Key Laboratory of Mesoscopic Chemistry MOE Key Laboratory of High Performance Polymer Materials and TechnologyJiangsu Key Laboratory of Advanced Organic MaterialsSuzhou Tierui New Energy Technology Co.LtdSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China School of the Environment and Safety Engineering Jiangsu UniversityZhenjiang 212013China

To solve the environmental pollution and low yield during the sythesis of zeolitic imidazolate frameworks(ZIFs)and their derived materials,a KOH-assisted aqueous strategy is proposed to synthesize cobalt zeolitic imidazolate framework(ZIF-67)polyhedrons,which are used as precursors to prepare cobalt selenide/carbon composites with different crystal phases(Co_(0.85)Se,CoSe_2).When evaluated as anode material for lithium ion batteries,Co_(0.85)Se/C composites deliver a reversible capacity of 758.7 m A·h·g^(-1)with a capacity retention rate of 90.5%at 1.0 A·g^(-1)after 500 cycles,and the superior rate capability is 620 m A·h·g^(-1)at 2.0 A·g^(-1).The addition of KOH accelerates the production of ZIF-67 crystals by boosting deprotonation of dimethylimidazole,resulting in rapid growth and structures transition from two-dimensional to three-dimensional of ZIF-67 in aqueous solution,which greatly promotes the application of MOFs in the field of energy storage and conversion.

关键词： KOH-assisted strategy Synthesis Aqueous solution Nanostructure lithium-ion batteries Long cycle performance