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Mechanism of Slag Composition Change During Electroslag Remelting Process

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Journal of Iron and Steel Research International 2011年第10期18卷 24-28,53页

作者： ZHAO jun-xue chen Yan-mei LI Xiao-ming CUI Ya-ru LU Xiao-tao School of Metallurgical Engineering Xi＇an University of Architecture and Technology Xi＇an 710055 Shannxi China

The mass loss rate of CaF2-CaO-Al2O3-SiO2-MgO slag system originated from ANF-6 was studied with CaF2, CaO, Al2O3, SiO2 or MgO content as variables. The method of quadratic regression orthogonal design was used for the design and analysis of the experiment. The experimental results indicated that mass loss rate of slag can be increased by 6% with CaF2 changing from 50%to 65%. Mass loss increases with SiO2 , Al2O3 and MgO adding and decreases with CaO content increasing. Because of the reaction between oxide and fluoride in the slag pool, apparent mass loss of CaF2-Al2O3 CaO-SiO2 MgO slag system appears at melting point. This will cause obvious composition change of electroslag. In addition, the segregation occurs in the slag skin forming process. This is another reason causing the composition change of electroslag.

关键词： electroslag DSC-TG analysis quadratic regression orthogonal design composition change

Venom gland of the ichneumonid Diadromus collaris： morphology, ultrastructure and age-related changes

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Insect Science 2006年第2期13卷 137-143页

作者： WEI-DI LI RUI-XIAN YU xue-XIN chen jun-HUA HE Institute of Applied Entomology Zhejiang University Hangzhou China

Females of the solitary parasitoid Diadromus collaris （Insecta： Hymenoptera： Ichneumonidae） lay eggs in the pupae of Plutella xylostella （Lepidoptera： Plutellidae）, and the venom is synchronously injected into hosts. The venom apparatus consists of two glandular tubules terminating in a common reservoir, A ductule connects the reservoir with the sting apparatus, by which the reservoir content enters the latter. Secretory units line the two glandular tubules. All secretory cells belong to dermal gland type Ⅲ. Dermal gland cells in glandular tubules are more abundant and developed than those in the reservoir. There are extensive rough endoplasmic reticulum and electrondense vesicles, and the microvilli are well developed. By the cuticle-lined central funnel secretion products of secretory units reach the reservoir. Moreover, the secretory apparatus undergoes age-related changes. The secretory units in the venom gland are better developed and more vigorous 7 days after eclosion than those 1 day after eclosion; autolytic processes occur 15 days after eclosion, and the tissue of the reservoir is more prostrate 15 day after eclosion than those 1 day after eclosion. The ovipostion peak of this parasitoid, about 3-7 days after eclosion, corresponds with the period when the venom gland is highly developed in the life span of the wasp.

关键词： age-related changes Diadromus collaris Ichneumonidae morphology,ultrastructure venom gland

Targeting cholesterol trafficking to mitigate axonal degeneration in hereditary spastic paraplegia

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Neural Regeneration Research 2025年第5期20卷 1397-1398页

作者： Zhenyu chen xue-jun Li Department of Biomedical Sciences University of Illinois College of Medicine RockfordRockfordILUSA Department of Bioengineering University of Illinois at ChicagoChicagoILUSA

Axonal degeneration underlies many debilitating diseases including hereditary spastic paraplegia(HSP),a genetically and clinically diverse group of disorders characterized by spasticity and weakness of the lower *** is one significant cause of chronic neurodisability due to the lack of effective treatments and a wide range of onset ages from early childhood to 70 years.

关键词： degeneration diseases hereditary

Design of Equal Precision Frequency Meter Based on FPGA

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Engineering（科研） 2012年第10期4卷 696-700页

作者： Yi-yuan Fang xue-jun chen College of Electrical and Electronic Engineering Shanghai University of Engineering Science Shanghai China

To overcome the shortcoming that the traditional frequency measurement method does not meet the requirement of equal precision, a design method of equal precision frequency meter based on FPGA is proposed. The system modules are all realized in Altera’s FPGA chip EP2C35F672C8. Experimental results show that the system can measure frequencies with equal precision in the whole frequency range, and the measurement error is small. It achieves the requirement of equal precision measurements.

关键词： FPGA Equal Precision Frequency Measurement

CagA^+ *** Induces Akt1 Phosphorylation and Inhibits Transcription of p21^(WAF1/CIP1) and p27^(KIP1) via PI3K/Akt1 Pathway

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Biomedical and Environmental Sciences 2010年第4期23卷 273-278页

作者： SHU-PING LI xue-jun chen AI-HUA SUN JIN-FANG ZHAO JIE YAN State Key Laboratory for Diagnosis and Treatment of Infectious Diseases the First Affiliated Hospital of Zhejiang University Hangzhou 310003 Zhejiang China Department of Clinical Laboratory The Children's Hospital of Zhejiang University Hangzhou 310003 Zhejiang China Faculty of Basic Medicine Zhejiang Medical College Hangzhou 310053 Zhejiang China Department of Medical Microbiology and Parasitology Medical College of Zhejiang University Hangzhou 310058 Zhejiang China

Objective Cytotoxin-associated protein （CagA） of H. pylori has been confirmed to be closely associated with gastric inflammation and tumorigenesis, but the mechanism behind it is little understood. In this study, we try to determine roles of CagA＋ strain in activating PI3K/Akt1 signaling pathway, and affecting expression of p21WAF1/CIP1 and p27KIP1, and also in releasing IL-8 in host cells. Methods Akt1 phosphorylation and IL-8 levels of CagA＋ and CagAˉ strain infected AGS cells were detected by ELISAs. Two quantitative RT-PCRs were established to measure p21WAF1/CIP1 and p27KIP1 mRNA levels in the CagA＋ and CagAˉ strain infected cells. LY294002, an inhibitor of PI3K/Akt pathway, was used to define effect of the pathway in IL-8 release. Results CagA＋ strain could induce an obvious elevation of Akt1 phosphorylation in the infected AGS cells while CagAˉ strain failed to do so. The CagA＋ H. pylori strain infected AGS cells showed significant drops both in p21WAF1/CIP1 and p27KIP1 mRNA levels, whereas the CagAˉ H. pylori strain caused a remarkable increase in p21WAF1/CIP1 mRNA without affecting p27KIP1 gene transcription in the AGS cells. Both the CagA＋ and CagAˉ H. pylori strains enabled AGS cells to produce close elevated levels of IL-8, and the LY294002 block resulted in unexpected elevations of IL-8 levels. Conclusion CagA can activate PI3K/Akt1 pathway that plays an inhibitory role in IL-8 release in H. pylori infected AGS cells. Activation of PI3K/Akt1 pathway and subsequent negative regulation of p21^WAF1/CIP1 and p27^KIP1 expression might be involved in CagA-associated carcinogenesis.

关键词： Helicobater pylori CagA PI3K Akt1 p21^WAF1/CIP1 p27^KIP1 IL-8

Study of angiogenesis induced by metastatic and non-metastatic liver cancer by corneal micropocket model in nude mice

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World Journal of Gastroenterology 1999年第2期5卷 28-30页

作者： SUN Hui Chuan, LI Xiao Ming, xue Qiong, chen jun, GAO Dong Mei and TANG Zhao You

AIM To study the angiogenesis induced by liver cancer with different metastatic potentials using corneal micropocket model in nude *** Corneal micropockets were created in nude mice. Tumor tissues and liver tissues were implanted into the corneal micropockets. Angiogenesis was observed using a digital camera under slit-lamp biomicroscope, and compared among different grafts and incision alone. Vascular responses were recorded in regard to the range, number and length of new blood vessels toward the grafts or *** Vascular responses induced by tumor tissues were greater than those by incision alone and liver tissue grafts. LCI-D20 induced more intensive angiogenesis than *** Highly metastatic liver cancer LCI D20 was more angiogenic than low metastatic cancer LCI D35 and liver tissue. Micropocket was a useful model to study dynamic process of angiogenesis in vivo.

关键词： liver neoplasms angiogenesis corneal micropocket model neoplasms metastasis

Expression of soluble triggering receptor expression on myeloid cells-1 in pleural effusion

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Chinese Medical Journal 2008年第17期121卷 1656-1661页

作者： HUANG Lu-ying SHI Huan-zhong LIANG Qiu-li WU Yan-bin QIN xue-jun chen Yi-qiang Institute of Respiratory Diseases First Affiliated Hospital Guangxi Medical University Nanning Guangxi 530021 China

Background Triggering receptors expressed on myeloid cells （TREM） proteins are a family of cell surface receptors expressed broadly by cells of the myeloid lineage. The aim of this study was to investigate the clinical significance of soluble TREM-1 （sTREM-1） in pleural effusions, and to determine the effects of pneumonia on pleural sTREM-1 concentrations. Methods Pleural fluid was collected from 109 patients who presented to the respiratory institute （35 with malignant pleural effusion, 31 with tuberculous pleural effusion, 21 with bacterial pleural effusion, and 22 with transudate）. The concentrations of sTREM-1, tumor necrosis factor-a （TNF-a） and interleukin-113 （IL-113） were determined in effusion and serum samples by enzyme linked immunosorbent assay （ELISA）. Results The concentrations of sTREM-1 in bacterial pleural effusion were significantly higher than those in malignant, tuberculous, and transudative groups （all P 〈0.001）. An sTREM-1 cutoff value of 768.1 ng/L had a sensitivity of 86% and a specificity of 93%. Pleural sTREM-1 levels were positively correlated with levels of TNF-a and IL-113. Patients with complicating bacterial pneumonia did not have elevated concentration of sTREM-1 in pleural effusion when compared with patients without pneumonia. Conclusions Determination of pleural sTREM-1 may improve the ability of clinicians to differentiate pleural effusion patients of bacterial origin from those with other etiologies. The occurrence of bacterial pneumonia did not affect pleural sTREM-1 concentrations.

关键词： pleural effusion empyema infection

Protection of the Person: Value Cornerstone of the Chinese Civil Code under Compilation

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Social Sciences in China 2007年第1期28卷 27-37页

作者： xue jun chen Yongyi and Zhang Zhiping

I. ＂Protection of the Person＂ as the Value Cornerstone of Law All civil codes tend to mirror a certain sense of ethical value typical of a given society, a sense that in macroscopic terms determines the intrinsic spirit underlying the civil code in question and, in specific terms, exercises a profound impact on the concrete provisions designed therein. China needs to define its own civil code taking into account the characteristics of the era and its own cultural traditions, so different from those of the European continent in the 19^th century, when civil codes were there in the making.

关键词：中国民法典价值基础人的保护行为法律编纂模式

Research on interfacial cracking of a Cr coating/steel substrate with and without laser pre-quenching treatment under thermal fatigue loading

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Research on interfacial cracking of a Cr coating/steel subst...