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Guidelines and consensus:Jejunoileostomy for diabetes mellitussurgical norms and expert consensus(2023 version)

World Journal of Diabetes 2024年第11期15卷 2182-2188页

作者： Ji-Wei Shen Chun-Yong Ji xue-dong fang Bo Yang Tian Zhang Zheng-Cai Li Hua-Zhi Li Zhi-Yi Liu Jun Tang Chuan-Wen Liao Ji-Zhou Lu Xuan Yang Xin-Guo Zhang Department of General Surgery Heilongjiang Provincial People's HospitalHarbin 150036Heilongjiang ProvinceChina Department of General Surgery Zhengzhou Central HospitalZhengzhou 450007Henan ProvinceChina Department of General Surgery The Third Affiliated Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of General Surgery The Eighth Medical Center of the General Hospital of the People's Liberation ArmyBeijing 100091China Department of General Surgery 242 Affiliated Hospital of Shenyang Medical CollegeShenyang 110034Liaoning ProvinceChina Department of General Surgery Jingmen Petrochemical General Hospital in Hubei ProvinceJingmen 448001Hubei ProvinceChina Department of General Surgery Beijing Chuiyangliu Hospital Affiliated to Tsinghua UniversityBeijing 100022China Department of General Surgery The Fourth Hospital of Jilin UniversityChangchun 130011Jilin ProvinceChina Department of General Surgery The First People's Hospital of XiangtanXiangtan 411101Hunan ProvinceChina Department of General Surgery Jiangxi First People's HospitalNanchang 332000Jiangxi ProvinceChina Department of General Surgery The Third People's Hospital of Gansu ProvinceLanzhou 730020Gansu ProvinceChina Department of General Thoracic Surgery Liaoning Electric Power Center HospitalShenyang 110403Liaoning ProvinceChina Department of General Surgery The Third Medical Center of the General Hospital of the People's Liberation ArmyBeijing 100039China

Diabetes mellitus(DM)is a group of diseases characterized by high blood glucose caused by insufficient absolute or relative secretion of *** diagnosed,patients need long-term treatment with hypoglycemic ***,the existing first-line hypoglycemic drugs do not provide effective treatment for DM and its *** the past,the first generation and the second generation of weight loss surgery,such as gastric bypass and sleeve gastric surgery,had strict body mass index ***,post-surgery,patients are prone to fluctuating hypoglycemia,gastroesophageal reflux,and dumping ***,the curative effect of this type of surgery was compromised to a certain *** is a third-generation surgery for patients with DM,which has been shown to improve glucose and lipid metabolism,without changing the original gastrointestinal tract *** from previous weight loss surgeries,jejunoileostomy has been clinically observed to delay the development of DM-related ***,the postoperative complications are mild and do not affect the patient’s quality of *** on our clinical observations from multi-center large samples,our team developed a consensus on the operative period and perioperative management of jejunoileostomy as a reference for clinical researchers.

关键词： Surgical Diabetes Weight loss surgery Y-shaped anastomotic jejunal loops Jejunoileostomy

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Application of nanotechnology in reversing therapeutic resistance and controlling metastasis of colorectal cancer

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World Journal of Gastroenterology 2023年第13期29卷 1911-1941页

作者： Sheng-Nan Ren Zhan-Yi Zhang Rui-Jie Guo Da-Ren Wang fang-fang Chen xue-Bo Chen xue-dong fang Nanomedicine and Translational Research Center China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Bethune Third Clinical Medical College Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Gastrointestinal Colorectal and Anal SurgeryChina-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

Colorectal cancer(CRC)is the most common digestive malignancy across the *** first-line treatments applied in the routine clinical setting include surgery,chemotherapy,radiotherapy,targeted therapy,and ***,resistance to therapy has been identified as the major clinical challenge that fails the treatment method,leading to recurrence and distant *** increasing number of studies have been attempting to explore the underlying mechanisms of the resistance of CRC cells to different therapies,which can be summarized into two aspects:(1)The intrinsic characters and adapted alterations of CRC cells before and during treatment that regulate the drug metabolism,drug transport,drug target,and the activation of signaling pathways;and(2)the suppressive features of the tumor microenvironment(TME).To combat the issue of therapeutic resistance,effective strategies are warranted with a focus on the restoration of CRC cells’sensitivity to specific treatments as well as reprogramming impressive TME into stimulatory *** date,nanotechnology seems promising with scope for improvement of drug mobility,treatment efficacy,and reduction of systemic *** instinctive advantages offered by nanomaterials enable the diversity of loading cargoes to increase drug concentration and targeting specificity,as well as offer a platform for trying the combination of different treatments to eventually prevent tumor recurrence,metastasis,and reversion of therapy *** present review intends to summarize the known mechanisms of CRC resistance to chemotherapy,radiotherapy,immunotherapy,and targeted therapy,as well as the process of *** have also emphasized the recent application of nanomaterials in combating therapeutic resistance and preventing metastasis either by combining with other treatment approaches or *** summary,nanomedicine is an emerging technology with potential for CRC treatment;hence,efforts should be devoted to targetin

关键词： Colorectal cancer Therapeutic resistance Nanotechnology Drug delivery system Combined treatment

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基于BOPPPS模型的雷达专业课程教学设计与实践

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教育教学论坛 2024年第34期 13-16页

作者：李苗胡文华薛东方赵喜陆军工程大学石家庄校区河北石家庄050003

针对雷达专业课程教学现状,尝试将注重互动和反馈的BOPPPS模型应用于专业课程教学中。首先,基于雷达专业课程教学现状,阐述了运用BOPPPS模型解决此现状的理论内涵,并以典型课程中“基本雷达方程”这一堂课为例,基于BOPPPS模型的六个环... 详细信息

针对雷达专业课程教学现状,尝试将注重互动和反馈的BOPPPS模型应用于专业课程教学中。首先,基于雷达专业课程教学现状,阐述了运用BOPPPS模型解决此现状的理论内涵,并以典型课程中“基本雷达方程”这一堂课为例,基于BOPPPS模型的六个环节完成了教学设计,以加深学生对基本雷达方程的理解。结合教学实践,发现应用BOPPPS模型开展雷达专业课程教学具有独特的优势,是一种行之有效的方法,为雷达专业课程教学提供了新思路。

关键词： BOPPPS教学模型雷达专业课程教学设计

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A New Method for Solving Nonlinear Partial Differential Equations Based on Liquid Time-Constant Networks

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Journal of Systems Science & Complexity 2024年第2期37卷 480-493页

作者： SUN Jiuyun dong Huanhe fang Yong College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

In this paper,physics-informed liquid networks(PILNs)are proposed based on liquid time-constant networks(LTC)for solving nonlinear partial differential equations(PDEs).In this approach,the network state is controlled via ordinary differential equations(ODEs).The significant advantage is that neurons controlled by ODEs are more expressive compared to simple activation *** addition,the PILNs use difference schemes instead of automatic differentiation to construct the residuals of PDEs,which avoid information loss in the neighborhood of sampling *** this method draws on both the traveling wave method and physics-informed neural networks(PINNs),it has a better physical ***,the KdV equation and the nonlinear Schr¨odinger equation are solved to test the generalization ability of the *** the best of the authors’knowledge,this is the first deep learning method that uses ODEs to simulate the numerical solutions of PDEs.

关键词： Nonlinear partial differential equations numerical solutions physics-informed liquid networks physics-informed neural networks

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Picotesla fiberized diamond-based AC magnetometer

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Photonics Research 2024年第6期12卷 1250-1261页

作者： SHAO-CHUN ZHANG YONG LIU LONG-KUN SHAN xue-dong GAO JIA-QI GENG CUI YU YANG dong XIANG-dong CHEN GUANG-CAN GUO fang-WEN SUN CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China National Key Laboratory of ASIC Hebei Semiconductor Research InstituteShijiazhuang 050051China Electric Power Quantum Sensing Joint Laboratory of Anhui Province State Grid Anhui Electric Power Research InstituteHefei 230601China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China

Portable quantum sensors are crucial for developing practical quantum sensing and metrology *** nitrogen-vacancy(NV)centers in diamonds have emerged as one of the most promising candidates for compact quantum ***,due to the difficulty of coherently controlling the ensemble spin and noise suppression in a large volume,it often faces problems such as reduced sensitivity and narrowed bandwidth in integrated lensless ***,we propose a fluorescence signal treatment method for NV spin ensemble manipulation by the exponential fitting of spin polarization processes,instead of integrating the photon *** enables spin state readout with a high signal-to-noise ratio and applies to the pulse sensing protocols for large-volume NV *** on this,we further developed a fiberized diamond-based AC *** an XY8-N dynamical decoupling pulse sequence,we demonstrated a T_(2)-limited sensitivity of 8pT/√Hz and T_(1)-limited frequency resolution of 90 Hz over a wide frequency band from 100 kHz to 3 *** integrated diamond sensor leverages quantum coherence to achieve enhanced sensitivity in detecting AC magnetic fields,making it suitable for implementation in a compact and portable endoscopic sensor.

关键词： magnetometer quantum ensemble

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Rational design of superior catalysts from topological semimetals with nontrivial energy window

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Rare Metals 2024年第5期43卷 1956-1964页

作者： Min Zhao Li-Rong Wang Wei Liu Ming-Hang Li Ying Liu xue-fang Dai Guo-dong Liu Xiao-Ming Zhang Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Materials Science and Engineering ManufacturingHebei University of TechnologyTianjin 300130China

Materials featuring topological energy bands and nontrivial surface states hold significant promise in unlocking unprecedented opportunities for innovating electrocatalytic ***,it remains a challenge to realize superior topological catalysts which can carry both high catalytic activity and excellent catalytic ***,we propose that a family of Ni-based binary materials hosting fantasying topological conjunct-nodalpoint state and a large nontrivial energy window(NEWD)represents an ideal choice for such superior topological catalysts in hydrogen evolution *** presence of conjunct-nodal-points ensures long Fermi arcs on the surface,thereby enabling an extremely high catalytic *** NEWD plays a crucial role in stabilizing the high catalytic activity against external perturbations,such as strain and electron/hole *** roles for conjunctnodal-points and NEWD are substantiated by the observable weakening of catalytic performance during topological phase transitions,which result in the removal of the conjunct-nodal-points,NEWD and their corresponding long Fermi *** work unveils a hidden mechanism and opens a feasible route for developing superior quantum catalysts from novel topology point of view.

关键词： First-principles modeling Topological semimetal Nontrivial surface states Hydrogen evolution reaction

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Physical informed memory networks for solving PDEs:implementation and applications

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Communications in Theoretical Physics 2024年第2期76卷 51-61页

作者： Jiuyun Sun Huanhe dong Yong fang College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

With the advent of physics informed neural networks(PINNs),deep learning has gained interest for solving nonlinear partial differential equations(PDEs)in recent *** this paper,physics informed memory networks(PIMNs)are proposed as a new approach to solving PDEs by using physical laws and dynamic behavior of *** the fully connected structure of the PINNs,the PIMNs construct the long-term dependence of the dynamics behavior with the help of the long short-term memory ***,the PDEs residuals are approximated using difference schemes in the form of convolution filter,which avoids information loss at the neighborhood of the sampling ***,the performance of the PIMNs is assessed by solving the Kd V equation and the nonlinear Schr?dinger equation,and the effects of difference schemes,boundary conditions,network structure and mesh size on the solutions are *** show that the PIMNs are insensitive to boundary conditions and have excellent solution accuracy even with only the initial conditions.

关键词： nonlinear partial differential equations physics informed memory networks physics informed neural networks numerical solution

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Planning an adaptive reuse development of underutilized urban underground infrastructures:A case study of Qingdao,China

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Underground Space 2024年第1期14卷 18-33页

作者： Yong-Kang Qiao fang-Le Peng Yun-Hao dong Chun-fang Lu Research Center for Underground Space&Department of Geotechnical Engineering Tongji UniversityShanghai 200092China

Urban underground infrastructures(UUIs)are a vital component of built capital for urban ***,many cities are now home to a multitude of disused or underutilized UUIs,not least aged purpose-built underground facilities,causing a waste of valuable underground space resource *** the process of urban renewal,adaptive reuse can be an attractive solution to breathe new life into underutilized UUIs,while addressing some of the modern problems of the built environment by an economically feasible ***,there is a prevalent absence in the current literature of the overarching planning and decision-making approaches for an adaptive reuse development of underutilized *** the intention of addressing this shortfall,this paper first lays out development strategies,then sets the generic patterns for adaptive reuse of disused or underutilized *** the city of Qingdao,China as a case study,detailed planning and decision-making approaches with the aid of multi-source data and spatial analysis tools are *** is anticipated that the findings of this research will assist the adaptive reuse development of UUIs in providing theoretical guidance and empirical evidence,thereby enhancing the role of urban underground space use in contributing to urban revitalization and urban sustainability.

关键词： Urban underground infrastructures Underutilized Adaptive reuse Planning Urban renewal

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Finite Groups with Some Bounded Codegrees

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Acta Mathematica Sinica,English Series 2024年第7期40卷 1778-1784页

作者： dong fang YANG Yu ZENG Heng LV School of Mathematics and Statistics Southwest UniversityChongqing400715P.R.China Department of Mathematics Changshu Institute of TechnologyChangshu215500P.R.China

For a characterχof a finite group G,the number cod(χ) := ∣G:ker(χ)∣/χ(1)is called the codegree ofχ.In this paper,we give a solvability criterion for a finite group G depending on the minimum of the ratioχ(1)^(... 详细信息

关键词： Finite group codegree degree simple group

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Intensified warming suppressed the snowmelt in the Tibetan Plateau

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Advances in Climate Change Research 2024年第3期15卷 452-463页

作者： Xiang LI Peng CUI xue-Qin ZHANG fang ZHANG Key Lab of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China China‒Pakistan Joint Research Center on Earth Sciences Chinese Academy of Sciences and Higher Education CommissionIslamabad 45320Pakistan

Understanding how hydrological factors interrelate is crucial when examining the impact of climate warming on ***,these connections are often overlooked,leading to an unclear relationship between temperature and *** study investigates the complex interplay between temperature and snowmelt in the Tibetan Plateau from 1961 to 2020,focusing on how extreme high-temperature events affect the frequency of extreme *** a structural equation model,we detected three temperature-related factors that predominantly influenced snowmelt and extreme *** annual average temperature was found to have a significant indirect impact on snowmelt,mediated by changes in snowfall,snow depth and snow *** contrast,high-temperature days(daily maximum temperatures exceeding the 90th percentile)and heat waves(at least three consecutive high-temperature days)negatively affected extreme snowmelt directly or *** direct effect of increasing extreme temperature events was associated with an earlier onset of high-temperature periods,which accelerated snowmelt and shortened the duration of extreme snowmelt ***,the reduction in snow cover owing to warming emerged as a main factor suppressing snowmelt and extreme snowmelt *** also revealed spatiotemporal variations in the temperature‒snowmelt relationship that highly depended on changes in snowmelt *** study elucidated why warming suppresses snowmelt and extreme snowmelt events in the Tibetan Plateau,highlighting the mediating roles of snow-related and phenological *** findings will provide scientific support for climate simulation and water management policymaking in alpine regions worldwide.

关键词： Climate change Extreme temperature Snowmelt Structural equation model Tibetan Plateau

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